Carnosic Acid Induces Anti-Inflammatory Effects in Paraquat-Treated SH-SY5Y Cells Through a Mechanism Involving a Crosstalk Between the Nrf2/HO-1 Axis and NF-κB

Sulforaphane protects against acrolein-induced oxidative stress and inflammatory responses: modulation of Nrf-2 and COX-2 expression

(2016) Wang-Sen Qin et al.   Archives of Medical Science

Resveratrol and the mitochondria: From triggering the intrinsic apoptotic pathway to inducing mitochondrial biogenesis, a mechanistic view

(2016) Marcos Roberto de Oliveira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nrf2 activation in the treatment of neurodegenerative diseases: a focus on its role in mitochondrial bioenergetics and function

(2016) Noemí Esteras et al.   BIOLOGICAL CHEMISTRY

Carnosic acid nanoparticles suppress liver ischemia/reperfusion injury by inhibition of ROS, Caspases and NF-κB signaling pathway in mice

(2016) Hui Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Relevance of carnosic acid to the treatment of several health disorders: Molecular targets and mechanisms

(2016) Sana Bahri et al.   BIOMEDICINE & PHARMACOTHERAPY

Quercetin and the mitochondria: A mechanistic view

(2016) Marcos Roberto de Oliveira et al.   BIOTECHNOLOGY ADVANCES

Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions

(2016) Francesco Maione et al.   BRITISH JOURNAL OF PHARMACOLOGY

Carvedilol attenuates paraquat-induced lung injury by inhibition of proinflammatory cytokines, chemokine MCP-1, NF-κB activation and oxidative stress mediators

(2016) Keyvan Amirshahrokhi et al.   CYTOKINE

Perfluorocarbon attenuates inflammatory cytokines, oxidative stress and histopathologic changes in paraquat-induced acute lung injury in rats

(2016) Zahra Khalighi et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Curcumin by down-regulating NF-kB and elevating Nrf2, reduces brain edema and neurological dysfunction after cerebral I/R

(2016) Wei Li et al.   MICROVASCULAR RESEARCH

Tanshinone I Induces Mitochondrial Protection through an Nrf2-Dependent Mechanism in Paraquat-TreatedHuman Neuroblastoma SH-SY5Y Cells

(2016) Marcos Roberto de Oliveira et al.   MOLECULAR NEUROBIOLOGY

Carnosic Acid Protects Mitochondria of Human Neuroblastoma SH-SY5Y Cells Exposed to Paraquat Through Activation of the Nrf2/HO-1Axis

(2016) Marcos Roberto de Oliveira et al.   MOLECULAR NEUROBIOLOGY

Pinocembrin Provides Mitochondrial Protection by the Activation of the Erk1/2-Nrf2 Signaling Pathway in SH-SY5Y Neuroblastoma Cells Exposed to Paraquat

(2016) Marcos Roberto de Oliveira et al.   MOLECULAR NEUROBIOLOGY

Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome

(2016) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Nrf2—a Promising Therapeutic Target for Defensing Against Oxidative Stress in Stroke

(2016) Rongrong Zhang et al.   MOLECULAR NEUROBIOLOGY

Carnosol and Related Substances Modulate Chemokine and Cytokine Production in Macrophages and Chondrocytes

(2016) Joseph Schwager et al.   MOLECULES

The Effects of Ellagic Acid upon Brain Cells: A Mechanistic View and Future Directions

(2016) Marcos Roberto de Oliveira   NEUROCHEMICAL RESEARCH

Oxidative stress and mitochondrial dysfunction are the underlying events of dopaminergic neurodegeneration in homocysteine rat model of Parkinson's disease

(2016) Nivedita Bhattacharjee et al.   NEUROCHEMISTRY INTERNATIONAL

Nrf2 Is an Attractive Therapeutic Target for Retinal Diseases

(2016) Yasuhiro Nakagami   Oxidative Medicine and Cellular Longevity

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

(2016) Pierpaola Davalli et al.   Oxidative Medicine and Cellular Longevity

Modulation of mitochondrial dysfunction in neurodegenerative diseases via activation of nuclear factor erythroid-2-related factor 2 by food-derived compounds

(2016) Isabel Denzer et al.   PHARMACOLOGICAL RESEARCH

Epigallocatechin gallate and mitochondria—A story of life and death

(2016) Marcos Roberto de Oliveira et al.   PHARMACOLOGICAL RESEARCH

Protective effect of carnosic acid against paraquat-induced redox impairment and mitochondrial dysfunction in SH-SY5Y cells: Role for PI3K/Akt/Nrf2 pathway

(2016) Marcos Roberto de Oliveira et al.   TOXICOLOGY IN VITRO

Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

(2015) Marcos Roberto de Oliveira et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Dietary Components Carnosic Acid and Carnosol as Neuroprotective Agents: a Mechanistic View

(2015) Marcos Roberto de Oliveira   MOLECULAR NEUROBIOLOGY

Formation and Implications of Alpha-Synuclein Radical in Maneb- and Paraquat-Induced Models of Parkinson’s Disease

(2015) Ashutosh Kumar et al.   MOLECULAR NEUROBIOLOGY

Characterization of the lipopolysaccharide induced model of Parkinson's disease: Role of oxidative stress and neuroinflammation

(2015) Neha Sharma et al.   NEUROCHEMISTRY INTERNATIONAL

Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation

(2015) Yang Bai et al.   Oxidative Medicine and Cellular Longevity

The effects of baicalein and baicalin on mitochondrial function and dynamics: A review

(2015) Marcos Roberto de Oliveira et al.   PHARMACOLOGICAL RESEARCH

Neuroinflammation and demyelination from the point of nitrosative stress as a new target for neuroprotection

(2015) Srdjan Ljubisavljevic et al.   REVIEWS IN THE NEUROSCIENCES

Biliverdin reductase isozymes in metabolism

(2015) Luke O’Brien et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Natural Antioxidant Betanin Protects Rats from Paraquat-Induced Acute Lung Injury Interstitial Pneumonia

(2015) Junyan Han et al.   Biomed Research International

NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review

(2015) Ruey-Horng Shih et al.   Frontiers in Molecular Neuroscience

Protective effect of Xuebijing injection on paraquat-induced pulmonary injury via down-regulating the expression of p38 MAPK in rats

(2015) Ming-wei Liu et al.   BMC Complementary and Alternative Medicine

Transcription Factors NRF2 and NF-κB Are Coordinated Effectors of the Rho Family, GTP-binding Protein RAC1 during Inflammation

(2014) Antonio Cuadrado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Stress and Neurobiology of Demyelination

(2014) Srdjan Ljubisavljevic   MOLECULAR NEUROBIOLOGY

The Glutathione System: A New Drug Target in Neuroimmune Disorders

(2014) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases—A mechanistic approach

(2014) Maria Teresa Baltazar et al.   TOXICOLOGY LETTERS

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells — up regulation of Nrf2 expression and down regulation of NF-κB and COX-2

(2013) Periasamy Ramyaa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Toll-like receptors: Role in inflammation and therapeutic potential

(2013) Emma Kay et al.   BIOFACTORS

Nitric oxide and energy metabolism in mammals

(2013) Zhaolai Dai et al.   BIOFACTORS

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

The Role of Inflammatory and Oxidative Stress Mechanisms in the Pathogenesis of Parkinson’s Disease: Focus on Astrocytes

(2013) Rituraj Niranjan   MOLECULAR NEUROBIOLOGY

Neurodegeneration in Parkinson's Disease: Interactions of Oxidative Stress, Tryptophan Catabolites and Depression with Mitochondria and Sirtuins

(2013) George Anderson et al.   MOLECULAR NEUROBIOLOGY

The mechanisms of carnosic acid attenuates tumor necrosis factor-α-mediated inflammation and insulin resistance in 3T3-L1 adipocytes

(2013) Chia-Wen Tsai et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Neuroinflammation and oxidative stress: Co-conspirators in the pathology of Parkinson’s disease

(2013) Juliet M. Taylor et al.   NEUROCHEMISTRY INTERNATIONAL

Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells

(2013) Roberta Foresti et al.   PHARMACOLOGICAL RESEARCH

Glutathione synthesis

(2012) Shelly C. Lu   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The effects of vitamin A supplementation for 3 months on adult rat nigrostriatal axis: Increased monoamine oxidase enzyme activity, mitochondrial redox dysfunction, increased β-amyloid1–40 peptide and TNF-α contents, and susceptibility of mitochondria to an in vitro H2O2 challenge

(2012) Marcos Roberto de Oliveira et al.   BRAIN RESEARCH BULLETIN

Syk/Src Pathway-Targeted Inhibition of Skin Inflammatory Responses by Carnosic Acid

(2012) Jueun Oh et al.   MEDIATORS OF INFLAMMATION

The Absence of Nrf2 Enhances NF-B-Dependent Inflammation following Scratch Injury in Mouse Primary Cultured Astrocytes

(2012) Hao Pan et al.   MEDIATORS OF INFLAMMATION

Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: Plausible role of NF-κB

(2012) Muneeb U. Rehman et al.   TOXICOLOGY LETTERS

Biological targets of isothiocyanates

(2011) Kristin K. Brown et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

CO metabolism, sensing, and signaling

(2011) Francesca Gullotta et al.   BIOFACTORS

Increased 3-nitrotyrosine levels in mitochondrial membranes and impaired respiratory chain activity in brain regions of adult female rats submitted to daily vitamin A supplementation for 2 months

(2011) Marcos Roberto de Oliveira et al.   BRAIN RESEARCH BULLETIN

The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-aging

(2011) Cheng Luo et al.   MEDICAL HYPOTHESES

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

Role of nitric oxide produced by iNOS through NF-κB pathway in migration of cerebellar granule neurons induced by Lipopolysaccharide

(2010) Daniela Arias-Salvatierra et al.   CELLULAR SIGNALLING

Total and Mitochondrial Nitrosative Stress, Decreased Brain-Derived Neurotrophic Factor (BDNF) Levels and Glutamate Uptake, and Evidence of Endoplasmic Reticulum Stress in the Hippocampus of Vitamin A-Treated Rats

(2010) Marcos Roberto de Oliveira et al.   NEUROCHEMICAL RESEARCH

Paraquat induces cyclooxygenase-2 (COX-2) implicated toxicity in human neuroblastoma SH-SY5Y cells

(2010) Wonsuk Yang et al.   TOXICOLOGY LETTERS

The vicious circle between oxidative stress and inflammation in atherosclerosis

(2009) Maarten Hulsmans et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of cyclooxygenase-2 expression and prostaglandin E2 production in chondrocytes by avocado soybean unsaponifiables and epigallocatechin gallate

(2009) L.F. Heinecke et al.   OSTEOARTHRITIS AND CARTILAGE

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY

Oxidative and Inflammatory Pathways in Parkinson’s Disease

(2008) Rebecca L. Miller et al.   NEUROCHEMICAL RESEARCH

Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1

(2007) Takumi Satoh et al.   JOURNAL OF NEUROCHEMISTRY