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Ferulic Acid Regulates the Nrf2/Heme Oxygenase-1 System and Counteracts Trimethyltin-Induced Neuronal Damage in the Human Neuroblastoma Cell Line SH-SY5Y

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Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

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Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability

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HO-1 Signaling Activation by Pterostilbene Treatment Attenuates Mitochondrial Oxidative Damage Induced by Cerebral Ischemia Reperfusion Injury

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The Dietary Components Carnosic Acid and Carnosol as Neuroprotective Agents: a Mechanistic View

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Induction of the pi class of glutathione S-transferase by carnosic acid in rat Clone 9 cells via the p38/Nrf2 pathway

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The protective role of NAD(P)H:quinone oxidoreductase 1 on acetaminophen-induced liver injury is associated with prevention of adenosine triphosphate depletion and improvement of mitochondrial dysfunction

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Resveratrol Partially Prevents Rotenone-Induced Neurotoxicity in Dopaminergic SH-SY5Y Cells through Induction of Heme Oxygenase-1 Dependent Autophagy

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Heme oxygenase-1 protects against Alzheimer’s amyloid-β1-42-induced toxicity via carbon monoxide production

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Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells

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The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease

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Carnosic Acid Prevents 6-Hydroxydopamine-Induced Cell Death in SH-SY5Y Cells via Mediation of Glutathione Synthesis

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Administration of the Nrf2–ARE activators sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo

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Increased 3-nitrotyrosine levels in mitochondrial membranes and impaired respiratory chain activity in brain regions of adult female rats submitted to daily vitamin A supplementation for 2 months

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L-NAME cotreatment did prevent neither mitochondrial impairment nor behavioral abnormalities in adult Wistar rats treated with vitamin A supplementation

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Carnosic Acid Induces the NAD(P)H: Quinone Oxidoreductase 1 Expression in Rat Clone 9 Cells through the p38/Nuclear Factor Erythroid-2 Related Factor 2 Pathway

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Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress

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Vitamin A supplementation at pharmacological doses induces nitrosative stress on the hypothalamus of adult Wistar rats

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Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells

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Nitric Oxide-Mediated Toxicity in Paraquat-Exposed SH-SY5Y Cells: A Protective Role of 7-Nitroindazole

(2009) Miguel A. Ortiz-Ortiz et al.   NEUROTOXICITY RESEARCH

Regulation of apoptosis by the redox state of cytochrome c

(2008) Guy C. Brown et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Heme Oxygenase and Carbon Monoxide: Medicine Chemistry and Biological Effects Guest Editor: Yuji Naito Integrative Survival Response Evoked by Heme Oxygenase-1 and Heme Metabolites

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Identification of Genes Associated with Paraquat-Induced Toxicity in SH-SY5Y Cells by PCR Array Focused on Apoptotic Pathways

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Do Mitochondriotropic Antioxidants Prevent Chlorinative Stress-Induced Mitochondrial and Cellular Injury?

(2007) Matthew Whiteman et al.   ANTIOXIDANTS & REDOX SIGNALING

Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1

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