The determinants of alternative RNA splicing in human cells

Alternative Splicing May Not Be the Key to Proteome Complexity

(2017) Michael L. Tress et al.   TRENDS IN BIOCHEMICAL SCIENCES

Control of gene expression through the nonsense-mediated RNA decay pathway

(2017) Andrew Nickless et al.   Cell and Bioscience

Functional impact of splice isoform diversity in individual cells

(2016) K. Yap et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Connecting the dots: chromatin and alternative splicing in EMT

(2016) Jessica A. Warns et al.   Biochemistry and Cell Biology

Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II

(2016) Fernando Carrillo Oesterreich et al.   CELL

A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1

(2016) Rene Geissler et al.   GENES & DEVELOPMENT

Defective control of pre–messenger RNA splicing in human disease

(2016) Benoit Chabot et al.   JOURNAL OF CELL BIOLOGY

Nonsense-mediated mRNA decay in humans at a glance

(2016) Tatsuaki Kurosaki et al.   JOURNAL OF CELL SCIENCE

Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing

(2016) Tassa Saldi et al.   JOURNAL OF MOLECULAR BIOLOGY

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia

(2016) Sheng Li et al.   NATURE MEDICINE

Spatio-temporal regulations and functions of neuronal alternative RNA splicing in developing and adult brains

(2016) Takatoshi Iijima et al.   NEUROSCIENCE RESEARCH

Robust detection of alternative splicing in a population of single cells

(2016) Joshua D. Welch et al.   NUCLEIC ACIDS RESEARCH

Mechanism and regulation of the nonsense-mediated decay pathway

(2016) Nele Hug et al.   NUCLEIC ACIDS RESEARCH

Coupling between alternative polyadenylation and alternative splicing is limited to terminal introns

(2016) Maliheh Movassat et al.   RNA Biology

Brief Report: Alternative Splicing of Extra Domain A (EIIIA) of Fibronectin Plays a Tissue-Specific Role in Hematopoietic Homeostasis

(2016) Alessandro Malara et al.   STEM CELLS

Involvement of PARP1 in the regulation of alternative splicing

(2016) Elena Matveeva et al.   Cell Discovery

Computational Identification of Tissue-Specific Splicing Regulatory Elements in Human Genes from RNA-Seq Data

(2016) Eman Badr et al.   PLoS One

TALE-directed local modulation of H3K9 methylation shapes exon recognition

(2016) Nicole I. Bieberstein et al.   Scientific Reports

Splicing regulation in spinal muscular atrophy by an RNA structure formed by long-distance interactions

(2015) Natalia N. Singh et al.   Annals of the New York Academy of Sciences

Mechanisms and Regulation of Alternative Pre-mRNA Splicing

(2015) Yeon Lee et al.   Annual Review of Biochemistry

Accurate inference of isoforms from multiple sample RNA-Seq data

(2015) Masruba Tasnim et al.   BMC GENOMICS

Global variability in gene expression and alternative splicing is modulated by mitochondrial content

(2015) Raul Guantes et al.   GENOME RESEARCH

Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast

(2015) Danny A. Bitton et al.   GENOME RESEARCH

Unmasking alternative splicing inside protein-coding exons defines exitrons and their role in proteome plasticity

(2015) Yamile Marquez et al.   GENOME RESEARCH

Decoding of exon splicing patterns in the human RUNX1–RUNX1T1 fusion gene

(2015) Vasily V. Grinev et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Coupling and Coordination in Gene Expression Processes with Pre-mRNA Splicing

(2015) Kewu Pan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

p54nrb/NONO Regulates Cyclic AMP-Dependent Glucocorticoid Production by Modulating Phosphodiesterase mRNA Splicing and Degradation

(2015) Jia Yang Lu et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Splicing Factors by Alternative Splicing and NMD Is Conserved between Kingdoms Yet Evolutionarily Flexible

(2015) Liana F. Lareau et al.   MOLECULAR BIOLOGY AND EVOLUTION

Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status

(2015) Kristin Moore et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of alternative splicing at the single-cell level

(2015) L. Faigenbloom et al.   Molecular Systems Biology

Recursive splicing in long vertebrate genes

(2015) Christopher R. Sibley et al.   NATURE

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

(2015) Silvana Konermann et al.   NATURE

Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events

(2015) Hagen Tilgner et al.   NATURE BIOTECHNOLOGY

A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature

(2015) Inma Gonzalez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles

(2015) Bushra Raj et al.   NEURON

Splicing of many human genes involves sites embedded within introns

(2015) Steven Kelly et al.   NUCLEIC ACIDS RESEARCH

Regulation of mammalian transcription and splicing by Nuclear RNAi

(2015) Roya Kalantari et al.   NUCLEIC ACIDS RESEARCH

Widespread alternative and aberrant splicing revealed by lariat sequencing

(2015) Nicholas Stepankiw et al.   NUCLEIC ACIDS RESEARCH

Defective histone supply causes changes in RNA polymerase II elongation rate and cotranscriptional pre-mRNA splicing

(2015) Silvia Jimeno-González et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators

(2015) Qinghong Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP

(2015) Yong Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease-associated mutation inSRSF2misregulates splicing by altering RNA-binding affinities

(2015) Jian Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-sequential and multi-step splicing of the dystrophin transcript

(2015) Isabella Gazzoli et al.   RNA Biology

The role of short RNA loops in recognition of a single-hairpin exon derived from a mammalian-wide interspersed repeat

(2015) Jana Kralovicova et al.   RNA Biology

From polyadenylation to splicing: Dual role for mRNA 3' end formation factors

(2015) Ashish Misra et al.   RNA Biology

Long-range RNA pairings contribute to mutually exclusive splicing

(2015) Yuan Yue et al.   RNA

An alternative splicing event amplifies evolutionary differences between vertebrates

(2015) S. Gueroussov et al.   SCIENCE

A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature

(2015) Inma Gonzalez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HP1 Is Involved in Regulating the Global Impact of DNA Methylation on Alternative Splicing

(2015) Ahuvi Yearim et al.   Cell Reports

Genetic Interaction Mapping Reveals a Role for the SWI/SNF Nucleosome Remodeler in Spliceosome Activation in Fission Yeast

(2015) Kristin L. Patrick et al.   PLoS Genetics

Assessing long-distance RNA sequence connectivity via RNA-templated DNA–DNA ligation

(2015) Christian K Roy et al.   eLife

Full-length single-cell RNA-seq applied to a viral human cancer: applications to HPV expression and splicing analysis in HeLa S3 cells

(2015) Liang Wu et al.   GigaScience

Cosplicing network analysis of mammalian brain RNA-Seq data utilizing WGCNA and Mantel correlations

(2015) Ovidiu D. Iancu et al.   Frontiers in Genetics

Histone modifications involved in cassette exon inclusions: a quantitative and interpretable analysis

(2015) Hui Liu et al.   BMC GENOMICS

Building Robust Transcriptomes with Master Splicing Factors

(2014) Mohini Jangi et al.   CELL

Structural studies of the spliceosome: zooming into the heart of the machine

(2014) Wojciech P Galej et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate

(2014) Gilad Fuchs et al.   GENOME RESEARCH

Widespread intron retention in mammals functionally tunes transcriptomes

(2014) Ulrich Braunschweig et al.   GENOME RESEARCH

PMD patient mutations reveal a long-distance intronic interaction that regulates PLP1/DM20 alternative splicing

(2014) Jennifer R. Taube et al.   HUMAN MOLECULAR GENETICS

Protecting the proteome: Eukaryotic cotranslational quality control pathways

(2014) Jens Lykke-Andersen et al.   JOURNAL OF CELL BIOLOGY

Integrative analysis of many RNA-seq datasets to study alternative splicing

(2014) Wenyuan Li et al.   METHODS

Phosphoproteomics Screen Reveals Akt Isoform-Specific Signals Linking RNA Processing to Lung Cancer

(2014) Ioannis Sanidas et al.   MOLECULAR CELL

How Slow RNA Polymerase II Elongation Favors Alternative Exon Skipping

(2014) Gwendal Dujardin et al.   MOLECULAR CELL

A Splicing-Dependent Transcriptional Checkpoint Associated with Prespliceosome Formation

(2014) Keerthi T. Chathoth et al.   MOLECULAR CELL

Physiological state co-regulates thousands of mammalian mRNA splicing events at tandem splice sites and alternative exons

(2014) Karol Szafranski et al.   NUCLEIC ACIDS RESEARCH

Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing

(2014) Jeremy C. Davis-Turak et al.   NUCLEIC ACIDS RESEARCH

Oligophrenin-1 (OPHN1), a Gene Involved in X-Linked Intellectual Disability, Undergoes RNA Editing and Alternative Splicing during Human Brain Development

(2014) Sabina Barresi et al.   PLoS One

Defining a personal, allele-specific, and single-molecule long-read transcriptome

(2014) Hagen Tilgner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crosslinking-immunoprecipitation (iCLIP) analysis reveals global regulatory roles of hnRNP L

(2014) Oliver Rossbach et al.   RNA Biology

Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans

(2014) Sina Mozaffari-Jovin et al.   RNA Biology

De Novo Prediction of PTBP1 Binding and Splicing Targets Reveals Unexpected Features of Its RNA Recognition and Function

(2014) Areum Han et al.   PLoS Computational Biology

The functional consequences of intron retention: Alternative splicing coupled to NMD as a regulator of gene expression

(2013) Ying Ge et al.   BIOESSAYS

Inference of alternative splicing from RNA-Seq data with probabilistic splice graphs

(2013) Laura H. LeGault et al.   BIOINFORMATICS

Mechanistic insights into mutually exclusive splicing in dynamin 1

(2013) Mikita Suyama   BIOINFORMATICS

Alternative splicing of mutually exclusive exons—A review

(2013) Martin Pohl et al.   BIOSYSTEMS

Dynamic Integration of Splicing within Gene Regulatory Pathways

(2013) Ulrich Braunschweig et al.   CELL

Orchestrated Intron Retention Regulates Normal Granulocyte Differentiation

(2013) Justin J.-L. Wong et al.   CELL

Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

(2013) Alika K Maunakea et al.   CELL RESEARCH

Mechano-Regulation of Alternative Splicing

(2013) Huan Liu et al.   CURRENT GENOMICS

Spliceosome-mediated decay (SMD) regulates expression of nonintronic genes in budding yeast

(2013) A. Volanakis et al.   GENES & DEVELOPMENT

Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin

(2013) P. Mallinjoud et al.   GENOME RESEARCH

From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing

(2013) G. K. Marinov et al.   GENOME RESEARCH

Acquired Mutations That Affect Pre-mRNA Splicing in Hematologic Malignancies and Solid Tumors

(2013) L. M. Scott et al.   JNCI-Journal of the National Cancer Institute

Regulation of gene expression in mammalian nervous system through alternative pre-mRNA splicing coupled with RNA quality control mechanisms

(2013) Karen Yap et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing

(2013) G Barry et al.   MOLECULAR PSYCHIATRY

Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

(2013) Alex K. Shalek et al.   NATURE

A single-molecule long-read survey of the human transcriptome

(2013) Donald Sharon et al.   NATURE BIOTECHNOLOGY

Alternative splicing: a pivotal step between eukaryotic transcription and translation

(2013) Alberto R. Kornblihtt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

(2013) Michael T Lovci et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of alternative splicing by local histone modifications: potential roles for RNA-guided mechanisms

(2013) H.-L. Zhou et al.   NUCLEIC ACIDS RESEARCH

Pre-mRNA Splicing Is a Determinant of Nucleosome Organization

(2013) Hadas Keren-Shaul et al.   PLoS One

Modeling Exon Expression Using Histone Modifications

(2013) Shijia Zhu et al.   PLoS One

RNA splicing regulates the temporal order of TNF-induced gene expression

(2013) S. Hao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR)

(2013) O. Solomon et al.   RNA

RNA sequencing of cancer reveals novel splicing alterations

(2013) Jeyanthy Eswaran et al.   Scientific Reports

Cytoplasmic intron retention, function, splicing, and the sentinel RNA hypothesis

(2013) Peter T. Buckley et al.   Wiley Interdisciplinary Reviews-RNA

Phenotypic noise: effects of post-transcriptional regulatory processes affecting mRNA

(2013) Rinat Arbel-Goren et al.   Wiley Interdisciplinary Reviews-RNA

Tailoring of Membrane Proteins by Alternative Splicing of Pre-mRNA

(2012) Kathleen F. Mittendorf et al.   BIOCHEMISTRY

Integrating many co-splicing networks to reconstruct splicing regulatory modules

(2012) Chao Dai et al.   BMC Systems Biology

Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention

(2012) K. Yap et al.   GENES & DEVELOPMENT

Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs

(2012) H. Tilgner et al.   GENOME RESEARCH

NMD: a multifaceted response to premature translational termination

(2012) Stephanie Kervestin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A complex network of factors with overlapping affinities represses splicing through intronic elements

(2012) Yang Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intronic splicing enhancers, cognate splicing factors and context-dependent regulation rules

(2012) Yang Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mutually exclusive splicing regulates the Nav 1.6 sodium channel function through a combinatorial mechanism that involves three distinct splicing regulatory elements and their ligands

(2012) Lorena Zubović et al.   NUCLEIC ACIDS RESEARCH

HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing

(2012) Marco Preußner et al.   NUCLEIC ACIDS RESEARCH

A Multi-Exon-Skipping Detection Assay Reveals Surprising Diversity of Splice Isoforms of Spinal Muscular Atrophy Genes

(2012) Natalia N. Singh et al.   PLoS One

Perturbation of Chromatin Structure Globally Affects Localization and Recruitment of Splicing Factors

(2012) Ignacio E. Schor et al.   PLoS One

Nascent RNA structure modulates the transcriptional dynamics of RNA polymerases

(2012) B. Zamft et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6

(2012) I. Evsyukova et al.   RNA

Staying on message: ensuring fidelity in pre-mRNA splicing

(2012) Daniel R. Semlow et al.   TRENDS IN BIOCHEMICAL SCIENCES

A complex ‘mRNA degradation code’ controls gene expression during animal development

(2012) Claudio R. Alonso   TRENDS IN GENETICS

An RNA architectural locus control region involved in Dscam mutually exclusive splicing

(2012) Xuebin Wang et al.   Nature Communications

First Exon Length Controls Active Chromatin Signatures and Transcription

(2012) Nicole I. Bieberstein et al.   Cell Reports

Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins

(2012) Stephanie C. Huelga et al.   Cell Reports

Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing

(2012) Madapura M. Pradeepa et al.   PLoS Genetics

Degradation of mRNAs that lack a stop codon: a decade of nonstop progress

(2012) A. Alejandra Klauer et al.   Wiley Interdisciplinary Reviews-RNA

Exon and intron definition in pre-mRNA splicing

(2012) Laura De Conti et al.   Wiley Interdisciplinary Reviews-RNA

Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns

(2012) Joachim Weischenfeldt et al.   GENOME BIOLOGY

GC content around splice sites affects splicing through pre-mRNA secondary structures

(2011) Jing Zhang et al.   BMC GENOMICS

ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

(2011) Liuqing Yang et al.   CELL

Epigenetics in Alternative Pre-mRNA Splicing

(2011) Reini F. Luco et al.   CELL

RNA structure and the mechanisms of alternative splicing

(2011) C Joel McManus et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

SpliceAid 2: A database of human splicing factors expression data and RNA target motifs

(2011) Francesco Piva et al.   HUMAN MUTATION

Regulation of the Mutually Exclusive Exons 8a and 8 in the CaV1.2 Calcium Channel Transcript by Polypyrimidine Tract-binding Protein

(2011) Zhen Zhi Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA Helicase p68 (DDX5) Regulates tau Exon 10 Splicing by Modulating a Stem-Loop Structure at the 5' Splice Site

(2011) A. Kar et al.   MOLECULAR AND CELLULAR BIOLOGY

Cell-to-cell variability of alternative RNA splicing

(2011) Z. Waks et al.   Molecular Systems Biology

CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing

(2011) Sanjeev Shukla et al.   NATURE

Functional consequences of developmentally regulated alternative splicing

(2011) Auinash Kalsotra et al.   NATURE REVIEWS GENETICS

RNA secondary structure in mutually exclusive splicing

(2011) Yun Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone Deacetylase Activity Modulates Alternative Splicing

(2011) Jarmila Hnilicová et al.   PLoS One

Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner

(2011) H.-L. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic histone acetylation is critical for cotranscriptional spliceosome assembly and spliceosomal rearrangements

(2011) Felizza Q. Gunderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pre-mRNA splicing is a determinant of histone H3K36 methylation

(2011) S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Context-dependent splicing regulation

(2011) Shengdong Ke et al.   RNA Biology

The emerging role of pre-messenger RNA splicing in stress responses: Sending alternative messages and silent messengers

(2011) Martin Dutertre et al.   RNA Biology

Evidence for widespread association of mammalian splicing and conserved long-range RNA structures

(2011) D. D. Pervouchine et al.   RNA

An Alternative Splicing Network Links Cell-Cycle Control to Apoptosis

(2010) Michael J. Moore et al.   CELL

Interleukin and Interleukin Receptor Diversity: Role of Alternative Splicing

(2010) Anupama Sahoo et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Asf1 Can Promote Trimethylation of H3 K36 by Set2

(2010) L.-j. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

Splicing-Dependent RNA Polymerase Pausing in Yeast

(2010) Ross D. Alexander et al.   MOLECULAR CELL

Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons

(2010) Fernando Carrillo Oesterreich et al.   MOLECULAR CELL

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

(2010) Vidisha Tripathi et al.   MOLECULAR CELL

Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Overlapping splicing regulatory motifs—combinatorial effects on splicing

(2010) Amir Goren et al.   NUCLEIC ACIDS RESEARCH

Single molecule analysis of combinatorial splicing

(2010) Tim Conze et al.   NUCLEIC ACIDS RESEARCH

A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination

(2010) Sérgio F. de Almeida et al.   NUCLEIC ACIDS RESEARCH

Dual coding in alternative reading frames correlates with intrinsic protein disorder

(2010) E. Kovacs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spliceosomes walk the line: Splicing errors and their impact on cellular function

(2010) Shu-Ning Hsu et al.   RNA Biology

Competing RNA secondary structures are required for mutually exclusive splicing of the Dscam exon 6 cluster

(2010) G. E. May et al.   RNA

Regulation of Alternative Splicing by Histone Modifications

(2010) R. F. Luco et al.   SCIENCE

Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1

(2010) Marianna Teplova et al.   STRUCTURE

Genome-Wide Association between Branch Point Properties and Alternative Splicing

(2010) André Corvelo et al.   PLoS Computational Biology

Noisy Splicing Drives mRNA Isoform Diversity in Human Cells

(2010) Joseph K. Pickrell et al.   PLoS Genetics

An active role for splicing in 3′-end formation

(2010) Harold G. Martinson   Wiley Interdisciplinary Reviews-RNA

Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene

(2009) S.-C. Huang et al.   BLOOD

Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay

(2009) Zhenguo Zhang et al.   BMC BIOLOGY

Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response

(2009) A. Uemura et al.   JOURNAL OF CELL SCIENCE

Developmental Control of CaV1.2 L-Type Calcium Channel Splicing by Fox Proteins

(2009) Z. Z. Tang et al.   MOLECULAR AND CELLULAR BIOLOGY

Auto- and Cross-Regulation of the hnRNP L Proteins by Alternative Splicing

(2009) O. Rossbach et al.   MOLECULAR AND CELLULAR BIOLOGY

Biased Chromatin Signatures around Polyadenylation Sites and Exons

(2009) Noah Spies et al.   MOLECULAR CELL

Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

(2009) Mo Chen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Control of alternative splicing through siRNA-mediated transcriptional gene silencing

(2009) Mariano Alló et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional and Evolutionary Insights into Human Brain Development through Global Transcriptome Analysis

(2009) Matthew B. Johnson et al.   NEURON

Stochastic noise in splicing machinery

(2009) Eugene Melamud et al.   NUCLEIC ACIDS RESEARCH

A global comparison between nuclear and cytosolic transcriptomes reveals differential compartmentalization of alternative transcript isoforms

(2009) Liang Chen   NUCLEIC ACIDS RESEARCH

Structural implication of splicing stochastics

(2009) E. Melamud et al.   NUCLEIC ACIDS RESEARCH

Splice-site pairing is an intrinsically high fidelity process

(2009) Kristi L. Fox-Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing

(2009) M. B. Warf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection

(2009) J.-F. Fisette et al.   RNA

Nucleosomal Fluctuations Govern the Transcription Dynamics of RNA Polymerase II

(2009) C. Hodges et al.   SCIENCE

Role of RNA structure in regulating pre-mRNA splicing

(2009) M. Bryan Warf et al.   TRENDS IN BIOCHEMICAL SCIENCES

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

The multiple lives of NMD factors: balancing roles in gene and genome regulation

(2008) Olaf Isken et al.   NATURE REVIEWS GENETICS

Alternative Promoters Influence Alternative Splicing at the Genomic Level

(2008) Dedong Xin et al.   PLoS One

Conserved RNA secondary structures promote alternative splicing

(2008) P. J. Shepard et al.   RNA

Intronic Alus Influence Alternative Splicing

(2008) Galit Lev-Maor et al.   PLoS Genetics