Oligophrenin-1 (OPHN1), a Gene Involved in X-Linked Intellectual Disability, Undergoes RNA Editing and Alternative Splicing during Human Brain Development

Neuropathological features in a female fetus with OPHN1 deletion and cerebellar hypoplasia

(2013) Delphine Rocas et al.   European Journal of Medical Genetics

Rho GTPase signaling at the synapse: Implications for intellectual disability

(2013) Wei Ba et al.   EXPERIMENTAL CELL RESEARCH

A-to-I editing of protein coding and noncoding RNAs

(2012) Arka Mallela et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis

(2012) F Galeano et al.   ONCOGENE

Spatio-temporal regulation of ADAR editing during development in porcine neural tissues

(2012) Morten Venø et al.   RNA Biology

ADARs: allies or enemies? The importance of A-to-I RNA editing in human disease: from cancer to HIV-1

(2011) Angela Gallo et al.   BIOLOGICAL REVIEWS

Deregulation of the A-to-I RNA editing mechanism in psychiatric disorders

(2011) Gilad Silberberg et al.   HUMAN MOLECULAR GENETICS

Insertion of 16 amino acids in the BAR domain of the oligophrenin 1 protein causes mental retardation and cerebellar hypoplasia in an Italian family

(2011) Filomena Pirozzi et al.   HUMAN MUTATION

A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα

(2011) Pamela Valnegri et al.   NATURE NEUROSCIENCE

Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein

(2011) Balpreet Bhogal et al.   NATURE NEUROSCIENCE

A-to-I RNA editing and cancer: From pathology to basic science

(2011) Angela Gallo et al.   RNA Biology

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

DARNED: a DAtabase of RNa EDiting in humans

(2010) A. Kiran et al.   BIOINFORMATICS

Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats

(2010) Shoshana Greenberger et al.   BMC GENOMICS

Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats

(2010) Ling-Ling Chen et al.   CELL CYCLE

Novel intragenic deletion in OPHN1 in a family causing XLMR with cerebellar hypoplasia and distinctive facial appearance

(2010) M Al-Owain et al.   CLINICAL GENETICS

Inosine cyanoethylation identifies A-to-I RNA editing sites in the human transcriptome

(2010) Masayuki Sakurai et al.   Nature Chemical Biology

Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader–Willi syndrome

(2010) Michael V. Morabito et al.   NEUROBIOLOGY OF DISEASE

Alternative Splicing and Extensive RNA Editing of Human TPH2 Transcripts

(2010) Maik Grohmann et al.   PLoS One

Molecular diversity through RNA editing: a balancing act

(2010) Sanaz Farajollahi et al.   TRENDS IN GENETICS

The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors

(2009) N. Nadif Kasri et al.   GENES & DEVELOPMENT

Large-scale mRNA sequencing determines global regulation of RNA editing during brain development

(2009) H. Wahlstedt et al.   GENOME RESEARCH

Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour

(2009) Christine M. Doe et al.   HUMAN MOLECULAR GENETICS

Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation

(2009) Malik Khelfaoui et al.   HUMAN MOLECULAR GENETICS

Normal Development of Brain Circuits

(2009) Gregory Z Tau et al.   NEUROPSYCHOPHARMACOLOGY

Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing

(2009) J. B. Li et al.   SCIENCE

Association of syndromic mental retardation with an Xq12q13.1 duplication encompassing the oligophrenin 1 gene

(2008) Maria Francesca Bedeschi et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family

(2008) Alexander Eberth et al.   BIOCHEMICAL JOURNAL

Down-regulation of RNA Editing in Pediatric Astrocytomas

(2008) Caterina Cenci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function

(2008) Tim D. Werry et al.   PHARMACOLOGY & THERAPEUTICS

Intronic Alus Influence Alternative Splicing

(2008) Galit Lev-Maor et al.   PLoS Genetics

RNA editing in regulating gene expression in the brain

(2007) James E.C. Jepson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms