Control of gene expression through the nonsense-mediated RNA decay pathway
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Control of gene expression through the nonsense-mediated RNA decay pathway
Authors
Keywords
Nonsense-mediated decay, RNA surveillance, Gene expression, Human disease
Journal
Cell and Bioscience
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-05-19
DOI
10.1186/s13578-017-0153-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay
- (2016) Eleen Y. Shum et al. CELL
- Nonsense-mediated mRNA decay in humans at a glance
- (2016) Tatsuaki Kurosaki et al. JOURNAL OF CELL SCIENCE
- The nonsense-mediated RNA decay pathway is disrupted in inflammatory myofibroblastic tumors
- (2016) JingWei Lu et al. JOURNAL OF CLINICAL INVESTIGATION
- Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay
- (2016) Jana Sieber et al. MOLECULAR & CELLULAR PROTEOMICS
- Nonsense-Mediated Decay Restricts LncRNA Levels in Yeast Unless Blocked by Double-Stranded RNA Structure
- (2016) Maxime Wery et al. MOLECULAR CELL
- Mechanism and regulation of the nonsense-mediated decay pathway
- (2016) Nele Hug et al. NUCLEIC ACIDS RESEARCH
- Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact
- (2016) Evangelos D. Karousis et al. Wiley Interdisciplinary Reviews-RNA
- Degradation of Gadd45 mRNA by nonsense-mediated decay is essential for viability
- (2016) Jonathan O Nelson et al. eLife
- Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate
- (2016) Chih-Hong Lou et al. Stem Cell Reports
- Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story
- (2015) Feng He et al. Annual Review of Genetics
- Selenocysteine incorporation: A trump card in the game of mRNA decay
- (2015) Sumangala P. Shetty et al. BIOCHIMIE
- Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay
- (2015) T. Li et al. EMBO JOURNAL
- The unfolded protein response is shaped by the NMD pathway
- (2015) R. Karam et al. EMBO REPORTS
- A Combined Proteomics/Genomics Approach Links Hepatitis C Virus Infection with Nonsense-Mediated mRNA Decay
- (2015) Holly R. Ramage et al. MOLECULAR CELL
- Antisense oligonucleotide–directed inhibition of nonsense-mediated mRNA decay
- (2015) Tomoki T Nomakuchi et al. NATURE BIOTECHNOLOGY
- Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes
- (2015) Søren Lykke-Andersen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1
- (2015) Sami J. Barmada et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of elements in human long 3′ UTRs that inhibit nonsense-mediated decay
- (2015) Kalodiah G. Toma et al. RNA
- RNA degradation in antiviral immunity and autoimmunity
- (2015) Rachel E. Rigby et al. TRENDS IN IMMUNOLOGY
- Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics
- (2015) Maximilian W. Popp et al. Nature Communications
- Full UPF3B function is critical for neuronal differentiation of neural stem cells
- (2015) Tahani Alrahbeni et al. Molecular Brain
- A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy
- (2015) Qing Feng et al. eLife
- Quality control of transcription start site selection by nonsense-mediated-mRNA decay
- (2015) Christophe Malabat et al. eLife
- Identification and Characterization of Small Molecules That Inhibit Nonsense-Mediated RNA Decay and Suppress Nonsense p53 Mutations
- (2014) L. Martin et al. CANCER RESEARCH
- Nonsense-Mediated Decay Serves as a General Viral Restriction Mechanism in Plants
- (2014) Damien Garcia et al. Cell Host & Microbe
- The Host Nonsense-Mediated mRNA Decay Pathway Restricts Mammalian RNA Virus Replication
- (2014) Giuseppe Balistreri et al. Cell Host & Microbe
- Retroviral strategy to stabilize viral RNA
- (2014) Bao Lin Quek et al. CURRENT OPINION IN MICROBIOLOGY
- 5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion
- (2014) M. Bhuvanagiri et al. EMBO Molecular Medicine
- Regulation of Natural mRNAs by the Nonsense-Mediated mRNA Decay Pathway
- (2014) Megan Peccarelli et al. EUKARYOTIC CELL
- Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis
- (2014) K L Jackson et al. GENE THERAPY
- Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes
- (2014) Søren Lykke-Andersen et al. GENES & DEVELOPMENT
- Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway
- (2014) Ashton Trey Belew et al. NATURE
- The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma
- (2014) Chen Liu et al. NATURE MEDICINE
- Intracellular calcium regulates nonsense-mediated mRNA decay
- (2014) Andrew Nickless et al. NATURE MEDICINE
- Identification of SMG6 cleavage sites and a preferred RNA cleavage motif by global analysis of endogenous NMD targets in human cells
- (2014) Skye A. Schmidt et al. NUCLEIC ACIDS RESEARCH
- Stress-induced inhibition of nonsense-mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11
- (2014) L Martin et al. ONCOGENE
- Most Human Proteins Made in Both Nucleus and Cytoplasm Turn Over within Minutes
- (2014) Sabyasachi Baboo et al. PLoS One
- Nonsense-mediated decay factors are involved in the regulation of selenoprotein mRNA levels during selenium deficiency
- (2014) Ali Seyedali et al. RNA
- Translation of Small Open Reading Frames within Unannotated RNA Transcripts in Saccharomyces cerevisiae
- (2014) Jenna E. Smith et al. Cell Reports
- Posttranscriptional Control of the Stem Cell and Neurogenic Programs by the Nonsense-Mediated RNA Decay Pathway
- (2014) Chih H. Lou et al. Cell Reports
- Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes
- (2014) Sebastiaan van Heesch et al. GENOME BIOLOGY
- Orchestrated Intron Retention Regulates Normal Granulocyte Differentiation
- (2013) Justin J.-L. Wong et al. CELL
- Regulation of Axon Guidance by Compartmentalized Nonsense-Mediated mRNA Decay
- (2013) Dilek Colak et al. CELL
- Long Noncoding RNAs: Cellular Address Codes in Development and Disease
- (2013) Pedro J. Batista et al. CELL
- Ribosome profiling reveals resemblance between long non-coding RNAs and 5′ leaders of coding RNAs
- (2013) Guo-Liang Chew et al. DEVELOPMENT
- The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2
- (2013) B. Loh et al. GENES & DEVELOPMENT
- Temporal and spatial characterization of nonsense-mediated mRNA decay
- (2013) T. Trcek et al. GENES & DEVELOPMENT
- Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay
- (2013) J. A. Hurt et al. GENOME RESEARCH
- Contribution of copy number variants involving nonsense-mediated mRNA decay pathway genes to neuro-developmental disorders
- (2013) Lam S. Nguyen et al. HUMAN MOLECULAR GENETICS
- The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth
- (2013) Lachlan A. Jolly et al. HUMAN MOLECULAR GENETICS
- Expression of new antigens on tumor cells by inhibiting nonsense-mediated mRNA decay
- (2013) Eli Gilboa IMMUNOLOGIC RESEARCH
- Viral interference with host mRNA surveillance, the nonsense-mediated mRNA decay (NMD) pathway, through a new function of HTLV-1 Rex: implications for retroviral replication
- (2013) Kazumi Nakano et al. MICROBES AND INFECTION
- Inhibition of Nonsense-Mediated RNA Decay Activates Autophagy
- (2013) J. Wengrod et al. MOLECULAR AND CELLULAR BIOLOGY
- The genetic landscape of high-risk neuroblastoma
- (2013) Trevor J Pugh et al. NATURE GENETICS
- DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans
- (2013) Dasa Longman et al. NUCLEIC ACIDS RESEARCH
- The RNA Degradation Pathway Regulates the Function of GAS5 a Non-Coding RNA in Mammalian Cells
- (2013) Hidenori Tani et al. PLoS One
- Attenuation of Nonsense-Mediated mRNA Decay Enhances In Vivo Nonsense Suppression
- (2013) Kim M. Keeling et al. PLoS One
- Smg1 haploinsufficiency predisposes to tumor formation and inflammation
- (2013) Tara L. Roberts et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translation of pre-spliced RNAs in the nuclear compartment generates peptides for the MHC class I pathway
- (2013) S. Apcher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay
- (2013) Kusum K Singh et al. RNA Biology
- Gene Expression Regulation by Upstream Open Reading Frames and Human Disease
- (2013) Cristina Barbosa et al. PLoS Genetics
- Staufen-mediated mRNA decay
- (2013) Eonyoung Park et al. Wiley Interdisciplinary Reviews-RNA
- Identification of pyrimidine derivatives as hSMG-1 inhibitors
- (2012) Ariamala Gopalsamy et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Exome sequencing identifiesUPF3Bas the causative gene for a Chinese non-syndrome mental retardation pedigree
- (2012) X Xu et al. CLINICAL GENETICS
- The Human T-Lymphotropic Virus Type 1 Tax Protein Inhibits Nonsense-Mediated mRNA Decay by Interacting with INT6/EIF3E and UPF1
- (2012) V. Mocquet et al. JOURNAL OF VIROLOGY
- Landscape of transcription in human cells
- (2012) Sarah Djebali et al. NATURE
- SMG5–PNRC2 is functionally dominant compared with SMG5–SMG7 in mammalian nonsense-mediated mRNA decay
- (2012) Hana Cho et al. NUCLEIC ACIDS RESEARCH
- Rescue of nonsense mutations by amlexanox in human cells
- (2012) Sara Gonzalez-Hilarion et al. Orphanet Journal of Rare Diseases
- Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability
- (2012) Hidenori Tani et al. RNA Biology
- CWC22 Connects Pre-mRNA Splicing and Exon Junction Complex Assembly
- (2012) Anna-Lena Steckelberg et al. Cell Reports
- Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns
- (2012) Joachim Weischenfeldt et al. GENOME BIOLOGY
- Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
- (2011) Nicholas T. Ingolia et al. CELL
- Inhibition of Nonsense-Mediated RNA Decay by the Tumor Microenvironment Promotes Tumorigenesis
- (2011) D. Wang et al. MOLECULAR AND CELLULAR BIOLOGY
- RNA Homeostasis Governed by Cell Type-Specific and Branched Feedback Loops Acting on NMD
- (2011) Lulu Huang et al. MOLECULAR CELL
- Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay
- (2011) Ivone G. Bruno et al. MOLECULAR CELL
- Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish
- (2011) Corina Anastasaki et al. NUCLEIC ACIDS RESEARCH
- N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD
- (2011) Yukiko Okada-Katsuhata et al. NUCLEIC ACIDS RESEARCH
- Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice
- (2011) P. A. Frischmeyer-Guerrerio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autoregulation of the nonsense-mediated mRNA decay pathway in human cells
- (2011) H. Yepiskoposyan et al. RNA
- High-Resolution View of the Yeast Meiotic Program Revealed by Ribosome Profiling
- (2011) G. A. Brar et al. SCIENCE
- Upf1 Senses 3′UTR Length to Potentiate mRNA Decay
- (2010) J. Robert Hogg et al. CELL
- Post-transcriptional Defects of Antioxidant Selenoenzymes Cause Oxidative Stress under Methylmercury Exposure
- (2010) Fusako Usuki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nonsense-Mediated RNA Decay Regulation by Cellular Stress: Implications for Tumorigenesis
- (2010) L. B. Gardner MOLECULAR CANCER RESEARCH
- A novel frameshift mutation in UPF3B identified in brothers affected with childhood onset schizophrenia and autism spectrum disorders
- (2010) A M Addington et al. MOLECULAR PSYCHIATRY
- Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay
- (2010) Fernando Pastor et al. NATURE
- Endogenous ribosomal frameshift signals operate as mRNA destabilizing elements through at least two molecular pathways in yeast
- (2010) Ashton T. Belew et al. NUCLEIC ACIDS RESEARCH
- UPF2 Is a Critical Regulator of Liver Development, Function and Regeneration
- (2010) Lina A. Thoren et al. PLoS One
- Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay
- (2010) D. R. McIlwain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Nonsense-mediated mRNA Decay by the Natural Product Pateamine A through Eukaryotic Initiation Factor 4AIII
- (2009) Yongjun Dang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nonsense-Mediated mRNA Decay Effectors Are Essential for Zebrafish Embryonic Development and Survival
- (2009) N. Wittkopp et al. MOLECULAR AND CELLULAR BIOLOGY
- Mutations of the UPF3B gene, which encodes a protein widely expressed in neurons, are associated with nonspecific mental retardation with or without autism
- (2009) F Laumonnier et al. MOLECULAR PSYCHIATRY
- Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
- (2009) Mitchell Guttman et al. NATURE
- PRFdb: A database of computationally predicted eukaryotic programmed -1 ribosomal frameshift signals
- (2008) Ashton T Belew et al. BMC GENOMICS
- NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
- (2008) J. Weischenfeldt et al. GENES & DEVELOPMENT
- SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs
- (2008) C. Gong et al. GENES & DEVELOPMENT
- Nonsense Codons Trigger an RNA Partitioning Shift
- (2008) Angela D. Bhalla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Multiple Core Spliceosomal Proteins by Alternative Splicing-Coupled Nonsense-Mediated mRNA Decay
- (2008) A. L. Saltzman et al. MOLECULAR AND CELLULAR BIOLOGY
- Hypoxic Inhibition of Nonsense-Mediated RNA Decay Regulates Gene Expression and the Integrated Stress Response
- (2008) L. B. Gardner MOLECULAR AND CELLULAR BIOLOGY
- SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells
- (2008) Andrea B Eberle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers
- (2008) R Karam et al. ONCOGENE
- Nonsense-Mediated mRNA Decay Impacts MSI-Driven Carcinogenesis and Anti-Tumor Immunity in Colorectal Cancers
- (2008) Jamila El-Bchiri et al. PLoS One
- SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan
- (2008) E. Huntzinger et al. RNA
- A Competition between Stimulators and Antagonists of Upf Complex Recruitment Governs Human Nonsense-Mediated mRNA Decay
- (2008) Guramrit Singh et al. PLOS BIOLOGY
- Posttranscriptional Gene Regulation by Spatial Rearrangement of the 3′ Untranslated Region
- (2008) Andrea B Eberle et al. PLOS BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now