Human Antimicrobial Peptides in Bodily Fluids: Current Knowledge and Therapeutic Perspectives in the Postantibiotic Era

Development of a catheter functionalized by a polydopamine peptide coating with antimicrobial and antibiofilm properties

(2015) Kaiyang Lim et al.   Acta Biomaterialia

Eotaxin-3 (CCL26) exerts innate host defense activities that are modulated by mast cell proteases

(2015) A. Gela et al.   ALLERGY

Novel endosomolytic peptides for enhancing gene delivery in nanoparticles

(2015) Aqeel Ahmad et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Human Basal Tear Peptidome Characterization by CID, HCD, and ETD Followed by in Silico and in Vitro Analyses for Antimicrobial Peptide Identification

(2015) Mikel Azkargorta et al.   JOURNAL OF PROTEOME RESEARCH

Salivary peptidomic as a tool to disclose new potential antimicrobial peptides

(2015) Fábio Trindade et al.   Journal of Proteomics

APD3: the antimicrobial peptide database as a tool for research and education

(2015) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

Antimicrobial peptide resistance mediates resilience of prominent gut commensals during inflammation

(2015) T. W. Cullen et al.   SCIENCE

Anti-Staphylococcal Biofilm Effects of Human Cathelicidin Peptides

(2015) Biswajit Mishra et al.   ACS Medicinal Chemistry Letters

Antimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide Synthetases

(2014) Jeremy C. Henderson et al.   ACS Chemical Biology

Vipericidins: a novel family of cathelicidin-related peptides from the venom gland of South American pit vipers

(2014) C. B. Falcao et al.   AMINO ACIDS

Impedimetric Detection of Pathogenic Gram-Positive Bacteria Using an Antimicrobial Peptide from Class IIa Bacteriocins

(2014) Hashem Etayash et al.   ANALYTICAL CHEMISTRY

Effective Control of Salmonella Infections by Employing Combinations of Recombinant Antimicrobial Human β-Defensins hBD-1 and hBD-2

(2014) Soumitra Maiti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sonorensin: an Antimicrobial Peptide, Belonging to the Heterocycloanthracin Subfamily of Bacteriocins, from a New Marine Isolate, Bacillus sonorensis MT93

(2014) Lipsy Chopra et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Baceridin, a Cyclic Hexapeptide from an EpiphyticBacillusStrain, Inhibits the Proteasome

(2014) Jutta Niggemann et al.   CHEMBIOCHEM

New Role for Human α-Defensin 5 in the Fight against Hypervirulent Clostridium difficile Strains

(2014) Lucinda Furci et al.   INFECTION AND IMMUNITY

Phosphoethanolamine Decoration of Neisseria gonorrhoeae Lipid A Plays a Dual Immunostimulatory and Protective Role during Experimental Genital Tract Infection

(2014) M. Packiam et al.   INFECTION AND IMMUNITY

Site-Specific Mutation of the Sensor Kinase GraS in Staphylococcus aureus Alters the Adaptive Response to Distinct Cationic Antimicrobial Peptides

(2014) Ambrose L. Cheung et al.   INFECTION AND IMMUNITY

NAD-dependent ADP-ribosylation of the human antimicrobial and immune-modulatory peptide LL-37 by ADP-ribosyltransferase-1

(2014) Monica Picchianti et al.   Innate Immunity

Silicon microfluidic flow focusing devices for the production of size-controlled PLGA based drug loaded microparticles

(2014) Kieran Keohane et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A Cleavage-potentiated Fragment of Tear Lacritin Is Bactericidal

(2014) Robert L. McKown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LL-37 Peptide Enhancement of Signal Transduction by Toll-like Receptor 3 Is Regulated by pH

(2014) Divyendu Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Copsin, a Novel Peptide-based Fungal Antibiotic Interfering with the Peptidoglycan Synthesis

(2014) Andreas Essig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design and Evaluation of Peptide Nucleic Acid Probes for Specific Identification of Candida albicans

(2014) Hyun-Joong Kim et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Citrullination Alters Immunomodulatory Function of LL-37 Essential for Prevention of Endotoxin-Induced Sepsis

(2014) J. Koziel et al.   JOURNAL OF IMMUNOLOGY

Fetal Human Keratinocytes Produce Large Amounts of Antimicrobial Peptides: Involvement of Histone-Methylation Processes

(2014) Maria Gschwandtner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Liquefaction of Semen Generates and Later Degrades a Conserved Semenogelin Peptide That Enhances HIV Infection

(2014) N. R. Roan et al.   JOURNAL OF VIROLOGY

Differential profiles of salivary proteins with affinity toStreptococcus mutanslipoteichoic acid in caries-free and caries-positive human subjects

(2014) S.W. Hong et al.   Molecular Oral Microbiology

Biocompatibility of Antimicrobial Melimine Lenses

(2014) Debarun Dutta et al.   OPTOMETRY AND VISION SCIENCE

Gageotetrins A–C, Noncytotoxic Antimicrobial Linear Lipopeptides from a Marine Bacterium Bacillus subtilis

(2014) Fakir Shahidullah Tareq et al.   ORGANIC LETTERS

N-acylated Peptides Derived from Human Lactoferricin Perturb Organization of Cardiolipin and Phosphatidylethanolamine in Cell Membranes and Induce Defects in Escherichia coli Cell Division

(2014) Dagmar Zweytick et al.   PLoS One

1,25-Dihydroxyvitamin D3 Induces LL-37 and HBD-2 Production in Keratinocytes from Diabetic Foot Ulcers Promoting Wound Healing: An In Vitro Model

(2014) Irma Gonzalez-Curiel et al.   PLoS One

Molecular Grafting onto a Stable Framework Yields Novel Cyclic Peptides for the Treatment of Multiple Sclerosis

(2013) Conan K. Wang et al.   ACS Chemical Biology

Identification and Characterization of a Bacitracin Resistance Network in Enterococcus faecalis

(2013) Susanne Gebhard et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cationic Host Defence Peptides: Potential as Antiviral Therapeutics

(2013) Emily Gwyer Findlay et al.   BIODRUGS

Jmjd3 Controls Mesodermal and Cardiovascular Differentiation of Embryonic Stem Cells

(2013) Kisho Ohtani et al.   CIRCULATION RESEARCH

The differential diagnostic model for serous peptidomics in HBV carriers established by MALDI-TOF-MS analysis

(2013) Liyuan Tian et al.   CLINICAL BIOCHEMISTRY

Antimicrobial peptides and gut microbiota in homeostasis and pathology

(2013) Maureen J. Ostaff et al.   EMBO Molecular Medicine

Sequestration and Scavenging of Iron in Infection

(2013) Nermi L. Parrow et al.   INFECTION AND IMMUNITY

The Novel Human β-Defensin 114 Regulates Lipopolysaccharide (LPS)-mediated Inflammation and Protects Sperm from Motility Loss

(2013) Heguo Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyproline-II Helix in Proteins: Structure and Function

(2013) Alexei A. Adzhubei et al.   JOURNAL OF MOLECULAR BIOLOGY

Extensive in vivo Human Milk Peptidomics Reveals Specific Proteolysis Yielding Protective Antimicrobial Peptides

(2013) David C. Dallas et al.   JOURNAL OF PROTEOME RESEARCH

Antiviral Activity of Trappin-2 and Elafin In Vitro and In Vivo against Genital Herpes

(2013) A. G. Drannik et al.   JOURNAL OF VIROLOGY

Immune modulation by multifaceted cationic host defense (antimicrobial) peptides

(2013) Ashley L Hilchie et al.   Nature Chemical Biology

The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus

(2013) Silke M. Currie et al.   PLoS One

Chromogranin A-Derived Peptides Are Involved in Innate Immunity

(2012) R. Aslam et al.   CURRENT MEDICINAL CHEMISTRY

Lack of Lipid A Pyrophosphorylation and FunctionallptAReduces Inflammation by Neisseria Commensals

(2012) Constance M. John et al.   INFECTION AND IMMUNITY

θ-Defensins: Cyclic Peptides with Endless Potential: FIGURE 1.

(2012) Robert I. Lehrer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design of a Novel Cyclotide-Based CXCR4 Antagonist with Anti-Human Immunodeficiency Virus (HIV)-1 Activity

(2012) Teshome L. Aboye et al.   JOURNAL OF MEDICINAL CHEMISTRY

Human β-defensin 3 inhibits antibiotic-resistant Staphylococcus biofilm formation

(2012) Chen Zhu et al.   JOURNAL OF SURGICAL RESEARCH

Alpha-amylase is a human salivary protein with affinity to lipopolysaccharide ofAggregatibacter actinomycetemcomitans

(2012) J.E. Baik et al.   Molecular Oral Microbiology

PEP-FOLD: an updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides

(2012) P. Thevenet et al.   NUCLEIC ACIDS RESEARCH

The effect of histatin 5, adsorbed on PMMA and hydroxyapatite, onCandida albicanscolonization

(2012) D. Vukosavljevic et al.   YEAST

The Mechanism of Action of Antimicrobial Peptides: Lipid Vesicles vs. Bacteria

(2012) Manuel N. Melo et al.   Frontiers in Immunology

GraXSR Proteins Interact with the VraFG ABC Transporter To Form a Five-Component System Required for Cationic Antimicrobial Peptide Sensing and Resistance in Staphylococcus aureus

(2011) Mélanie Falord et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action

(2011) Marco Scocchi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Antimicrobial and antibiofilm activity of LL-37 and its truncated variants against Burkholderia pseudomallei

(2011) Sakawrat Kanthawong et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Coevolution of ABC Transporters and Two-Component Regulatory Systems as Resistance Modules against Antimicrobial Peptides in Firmicutes Bacteria

(2011) S. Dintner et al.   JOURNAL OF BACTERIOLOGY

Peptidomics-Based Discovery of an Antimicrobial Peptide Derived from Insulin-Like Growth Factor-Binding Protein 5

(2011) Tsukasa Osaki et al.   JOURNAL OF PROTEOME RESEARCH

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1

(2011) Bjoern O. Schroeder et al.   NATURE

Effects of cathelicidin and its fragments on three key enzymes of HIV-1

(2011) Jack Ho Wong et al.   PEPTIDES

Lipooligosaccharide Structure is an Important Determinant in the Resistance of Neisseria Gonorrhoeae to Antimicrobial Agents of Innate Host Defense

(2011) Jacqueline T. Balthazar et al.   Frontiers in Microbiology

Porous Polymer Monolithic Column with Surface-Bound Gold Nanoparticles for the Capture and Separation of Cysteine-Containing Peptides

(2010) Yan Xu et al.   ANALYTICAL CHEMISTRY

An Antimicrobial Peptide That Targets DNA Repair Intermediates In Vitro Inhibits Salmonella Growth within Murine Macrophages

(2010) L. Y. Su et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Probing the “Charge Cluster Mechanism” in Amphipathic Helical Cationic Antimicrobial Peptides

(2010) Raquel F. Epand et al.   BIOCHEMISTRY

Immunocytochemical and immunoelectron microscopic demonstration of cathepsin B in human malignant melanoma

(2010) E. FRÖHLICH et al.   BRITISH JOURNAL OF DERMATOLOGY

Optimization and High-Throughput Screening of Antimicrobial Peptides

(2010) Sylvie E. Blondelle et al.   CURRENT PHARMACEUTICAL DESIGN

Human  -Defensin 3 Inhibits Cell Wall Biosynthesis in Staphylococci

(2010) V. Sass et al.   INFECTION AND IMMUNITY

Phosphoryl Moieties of Lipid A from Neisseria meningitidis and N. gonorrhoeae Lipooligosaccharides Play an Important Role in Activation of Both MyD88- and TRIF-Dependent TLR4-MD-2 Signaling Pathways

(2010) M. Liu et al.   JOURNAL OF IMMUNOLOGY

Bacterial membrane lipids in the action of antimicrobial agents

(2010) Richard M. Epand et al.   JOURNAL OF PEPTIDE SCIENCE

The endogenous peptides of normal human serum extracted from the acetonitrile-insoluble precipitate using modified aqueous buffer with analysis by LC–ESI–Paul ion trap and Qq-TOF

(2010) Monika Tucholska et al.   Journal of Proteomics

The appearance of dermcidin isoform 2, a novel platelet aggregating agent in the circulation in acute myocardial infarction that inhibits insulin synthesis and the restoration by acetyl salicylic acid of its effects

(2010) Rajeshwary Ghosh et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease

(2010) David M. Good et al.   MOLECULAR & CELLULAR PROTEOMICS

The human cathelicidin hCAP18/LL-37: A multifunctional peptide involved in mycobacterial infections

(2010) Patricia Méndez-Samperio   PEPTIDES

Uropathogenic Escherichia coli Modulates Immune Responses and Its Curli Fimbriae Interact with the Antimicrobial Peptide LL-37

(2010) Ylva Kai-Larsen et al.   PLoS Pathogens

Sensitivity of Candida albicans biofilm cells grown on denture acrylic to antifungal proteins and chlorhexidine

(2009) Christopher R. Pusateri et al.   ARCHIVES OF ORAL BIOLOGY

Immunoassays for the incretin hormones GIP and GLP-1

(2009) Carolyn F. Deacon et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2

(2009) M. Nairz et al.   BLOOD

Methionine-enkephalin secreted by human colorectal cancer cells suppresses T lymphocytes

(2009) Hitoshi Ohmori et al.   CANCER SCIENCE

Low Plasma Level of Cathelicidin Antimicrobial Peptide (hCAP18) Predicts Increased Infectious Disease Mortality in Patients Undergoing Hemodialysis

(2009) Adrian F. Gombart et al.   CLINICAL INFECTIOUS DISEASES

CAP37-Derived Antimicrobial Peptides HaveIn VitroAntiviral Activity against Adenovirus and Herpes Simplex Virus Type 1

(2009) Y. Jerold Gordon et al.   CURRENT EYE RESEARCH

Salivary antimicrobial peptides (LL-37 and alpha-defensins HNP1–3), antimicrobial and IgA responses to prolonged exercise

(2009) Glen Davison et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Hepcidin Revisited, Disulfide Connectivity, Dynamics, and Structure

(2009) John B. Jordan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

(2009) Yuping Lai et al.   TRENDS IN IMMUNOLOGY

Capillary electrophoresis-electrospray-mass spectrometry in peptide analysis and peptidomics

(2008) Miguel Herrero et al.   ELECTROPHORESIS

Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation

(2008) J. Overhage et al.   INFECTION AND IMMUNITY

Mast Cell and Monocyte Recruitment by S100A12 and Its Hinge Domain

(2008) Wei Xing Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of Human Host Defense Cathelicidin LL-37 and Its Smallest Antimicrobial Peptide KR-12 in Lipid Micelles

(2008) Guangshun Wang   JOURNAL OF BIOLOGICAL CHEMISTRY

Capsule polysaccharide is a bacterial decoy for antimicrobial peptides

(2008) E. Llobet et al.   MICROBIOLOGY-SGM

Antioxidant Peptidomics Reveals Novel Skin Antioxidant System

(2008) Hailong Yang et al.   MOLECULAR & CELLULAR PROTEOMICS

Uptake of the antifungal cationic peptide Histatin 5 byCandida albicansSsa2p requires binding to non-conventional sites within the ATPase domain

(2008) Jianing N. Sun et al.   MOLECULAR MICROBIOLOGY

Identification of novel semenogelin I-derived antimicrobial peptide from liquefied human seminal plasma

(2008) Hui Zhao et al.   PEPTIDES

The Antimicrobial Peptide Histatin-5 Causes a Spatially Restricted Disruption on the Candida albicans Surface, Allowing Rapid Entry of the Peptide into the Cytoplasm

(2008) A. Brian Mochon et al.   PLoS Pathogens

A simple model for polyproline II structure in unfolded states of alanine-based peptides

(2002) Rohit V. Pappu et al.   PROTEIN SCIENCE