Immune modulation of some autoimmune diseases: the critical role of macrophages and neutrophils in the innate and adaptive immunity

Elevated Leukocyte Azurophilic Enzymes in Human Diabetic Ketoacidosis Plasma Degrade Cerebrovascular Endothelial Junctional Proteins*

(2016) Martin M. H. Woo et al.   CRITICAL CARE MEDICINE

Environmental risk factors for type 1 diabetes

(2016) Marian Rewers et al.   LANCET

Neutrophils in type 1 diabetes

(2016) Juan Huang et al.   Journal of Diabetes Investigation

Plasticity of neutrophils reveals modulatory capacity

(2015) S.M. Perobelli et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Monocyte trafficking across the vessel wall

(2015) Teresa Gerhardt et al.   CARDIOVASCULAR RESEARCH

Lactoferrin Inhibits IL-1β-Induced Chondrocyte Apoptosis Through AKT1-Induced CREB1 Activation

(2015) Huaming Xue et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The CXCR1/2 Pathway: Involvement in Diabetes Pathophysiology and Potential Target for T1D Interventions

(2015) Antonio Citro et al.   Current Diabetes Reports

Macrophage-T Cell Interactions Mediate Neuropathic Pain through the Glucocorticoid-induced Tumor Necrosis Factor Ligand System

(2015) Yuka Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of human autoimmunity

(2015) Michael D. Rosenblum et al.   JOURNAL OF CLINICAL INVESTIGATION

Angiogenesis and lymphangiogenesis in inflammatory skin disorders

(2015) Gilda Varricchi et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Intestinal Monocyte-Derived Macrophages Control Commensal-Specific Th17 Responses

(2015) Casandra Panea et al.   Cell Reports

The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis

(2015) Ceri A. Roberts et al.   Frontiers in Immunology

CXCL1/CXCL8 (GROα/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro

(2014) Tatsushi Omatsu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages

(2014) Yasutaka Okabe et al.   CELL

Role of cathepsin B in regulating migration and invasion of fibroblast-like synoviocytes into inflamed tissue from patients with rheumatoid arthritis

(2014) B. Tong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CXCR1/2 Inhibition Blocks and Reverses Type 1 Diabetes in Mice

(2014) Antonio Citro et al.   DIABETES

Increased Neutrophil Elastase and Proteinase 3 and Augmented NETosis Are Closely Associated With  -Cell Autoimmunity in Patients With Type 1 Diabetes

(2014) Y. Wang et al.   DIABETES

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

(2014) Slava Epelman et al.   IMMUNITY

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Role of immune system in type 1 diabetes mellitus pathogenesis

(2014) Leszek Szablewski   INTERNATIONAL IMMUNOPHARMACOLOGY

Macrophage Polarization in Inflammatory Diseases

(2014) Yan-Cun Liu et al.   International Journal of Biological Sciences

Neutrophil contribution to spinal cord injury and repair

(2014) Virginie Neirinckx et al.   Journal of Neuroinflammation

The heterogenic properties of monocytes/macrophages and neutrophils in inflammatory response in diabetes

(2014) Xiaoquan Rao et al.   LIFE SCIENCES

TLR2 Elicits IL-17-Mediated RANKL Expression, IL-17, and OPG Production in Neutrophils from Arthritic Mice

(2014) Viktoriya Milanova et al.   MEDIATORS OF INFLAMMATION

Macrophage subsets in atherosclerosis

(2014) Giulia Chinetti-Gbaguidi et al.   Nature Reviews Cardiology

The multifactorial role of neutrophils in rheumatoid arthritis

(2014) Helen L. Wright et al.   Nature Reviews Rheumatology

Interleukin-10 attenuation of collagen-induced arthritis is associated with suppression of interleukin-17 and retinoid-related orphan receptor γt production in macrophages and repression of classically activated macrophages

(2014) Liang Ye et al.   ARTHRITIS RESEARCH & THERAPY

Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?

(2014) Michael James Kraakman et al.   Frontiers in Immunology

Complement, C1q, and C1q-Related Molecules Regulate Macrophage Polarization

(2014) Suzanne S. Bohlson et al.   Frontiers in Immunology

Antibodies from patients with rheumatoid arthritis target citrullinated histone 4 contained in neutrophils extracellular traps

(2013) Federico Pratesi et al.   ANNALS OF THE RHEUMATIC DISEASES

Heightened immune response to autocitrullinatedPorphyromonas gingivalispeptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis

(2013) Anne-Marie Quirke et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophils and type 1 autoimmune diabetes

(2013) Manuela Battaglia   CURRENT OPINION IN HEMATOLOGY

Reduction of Circulating Neutrophils Precedes and Accompanies Type 1 Diabetes

(2013) A. Valle et al.   DIABETES

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Diverse novel functions of neutrophils in immunity, inflammation, and beyond

(2013) Attila Mócsai   JOURNAL OF EXPERIMENTAL MEDICINE

Cross-linking of IgGs bound on circulating neutrophils leads to an activation of endothelial cells: possible role of rheumatoid factors in rheumatoid arthritis-associated vascular dysfunction

(2013) Emmanuelle Rollet-Labelle et al.   Journal of Inflammation-London

Neutrophils in local and systemic antibody-dependent inflammatory and anaphylactic reactions

(2013) Friederike Jönsson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Genetics and epigenetics of rheumatoid arthritis

(2013) Sebastien Viatte et al.   Nature Reviews Rheumatology

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Neutrophils in innate and adaptive immunity

(2013) Sébastien Jaillon et al.   Seminars in Immunopathology

Role of neutrophils in systemic autoimmune diseases

(2013) Mariana J Kaplan   ARTHRITIS RESEARCH & THERAPY

Structural Changes and Antibody Enrichment in the Lungs Are Early Features of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis

(2013) Gudrun Reynisdottir et al.   Arthritis & Rheumatology

Association of age-related changes in circulating intermediary lipid metabolites, inflammatory and oxidative stress markers, and arterial stiffness in middle-aged men

(2012) Ji Young Kim et al.   AGE

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Neutrophil extracellular traps in sterile inflammation: the story after dying?

(2012) Bei-Bei Cui et al.   AUTOIMMUNITY

Efferocytosis Is an Innate Antibacterial Mechanism

(2012) Constance J. Martin et al.   Cell Host & Microbe

Plasma high sensitivity C-reactive protein and its relationship with cytokine levels in children with newly diagnosed type 1 diabetes and ketoacidosis

(2012) Kyriaki Karavanaki et al.   CLINICAL BIOCHEMISTRY

Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

(2012) Baptiste N. Jaeger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17 and TNF-  Sustain Neutrophil Recruitment during Inflammation through Synergistic Effects on Endothelial Activation

(2012) G. K. Griffin et al.   JOURNAL OF IMMUNOLOGY

Alternatively Activated Macrophages in Types 1 and 2 Diabetes

(2012) Arlett Espinoza-Jiménez et al.   MEDIATORS OF INFLAMMATION

Early ontogenic origin of the hematopoietic stem cell lineage

(2012) Y. Tanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting monocytes/macrophages in the treatment of rheumatoid arthritis

(2012) J.-L. Davignon et al.   RHEUMATOLOGY

Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis

(2012) Carmen A Ambarus et al.   ARTHRITIS RESEARCH & THERAPY

Managing Macrophages in Rheumatoid Arthritis by Reform or Removal

(2012) Jun Li et al.   Current Rheumatology Reports

Neutrophils and Macrophages: the Main Partners of Phagocyte Cell Systems

(2012) Manuel T. Silva et al.   Frontiers in Immunology

Macrophages and Tissue Injury: Agents of Defense or Destruction?

(2011) Debra L. Laskin et al.   Annual Review of Pharmacology and Toxicology

Sex differences in spontaneous versus induced animal models of autoimmunity

(2011) Tai-Ping Lee et al.   AUTOIMMUNITY REVIEWS

Macrophages and neutrophils in SLE—An online molecular catalog

(2011) Jacob Orme et al.   AUTOIMMUNITY REVIEWS

Serum CXCL1 concentrations are elevated in type 1 diabetes mellitus, possibly reflecting activity of anti-islet autoimmune activity

(2011) Kazuma Takahashi et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Mouse neutrophils are professional antigen-presenting cells programmed to instruct Th1 and Th17 T-cell differentiation

(2011) D. S. Abi Abdallah et al.   INTERNATIONAL IMMUNOLOGY

Restoration of anti-Aspergillus defense by neutrophil extracellular traps in human chronic granulomatous disease after gene therapy is calprotectin-dependent

(2011) Matteo Bianchi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Myeloperoxidase associated with neutrophil extracellular traps is active and mediates bacterial killing in the presence of hydrogen peroxide

(2011) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

(2011) Irene Puga et al.   NATURE IMMUNOLOGY

The neutrophil in vascular inflammation

(2011) Mia Phillipson et al.   NATURE MEDICINE

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute Lung Injury: How Macrophages Orchestrate Resolution of Inflammation and Tissue Repair

(2011) Susanne Herold et al.   Frontiers in Immunology

What do we mean when we write “senescence,”“apoptosis,”“necrosis,” or “clearance of dying cells”?

(2010) Dror Mevorach et al.   Annals of the New York Academy of Sciences

Changes in expression of membrane TNF, NF- B activation and neutrophil apoptosis during active and resolved inflammation

(2010) H. L. Wright et al.   ANNALS OF THE RHEUMATIC DISEASES

Human neutrophils interact with both 6-sulfo LacNAc+ DC and NK cells to amplify NK-derived IFN : role of CD18, ICAM-1, and ICAM-3

(2010) C. Costantini et al.   BLOOD

CCR7 is involved in the migration of neutrophils to lymph nodes

(2010) C. Beauvillain et al.   BLOOD

IFNγ primes macrophages for inflammatory activation by high molecular weight hyaluronan

(2010) Mark A. Wallet et al.   CELLULAR IMMUNOLOGY

Correlation of a multi-cytokine panel with clinical disease activity in patients with rheumatoid arthritis

(2010) Nataliya Milman et al.   CLINICAL BIOCHEMISTRY

Biology of interleukin-10

(2010) Robert Sabat et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Neutrophils, from Marrow to Microbes

(2010) Niels Borregaard   IMMUNITY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Neutrophil activation and survival are modulated by interaction with NK cells

(2010) C. Costantini et al.   INTERNATIONAL IMMUNOLOGY

Neutrophils: Cinderella of innate immune system

(2010) V. Kumar et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Expression of CD147 (EMMPRIN) on neutrophils in rheumatoid arthritis enhances chemotaxis, matrix metalloproteinase production and invasiveness of synoviocytes

(2010) Cong-Hua Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

(2010) Kyle J. Eash et al.   JOURNAL OF CLINICAL INVESTIGATION

Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums

(2010) Kodi S. Ravichandran   JOURNAL OF EXPERIMENTAL MEDICINE

Production of Vascular Endothelial Growth Factors from Human Lung Macrophages Induced by Group IIA and Group X Secreted Phospholipases A2

(2010) F. Granata et al.   JOURNAL OF IMMUNOLOGY

Neutrophils Influence the Level of Antigen Presentation during the Immune Response to Protein Antigens in Adjuvants

(2010) C.-W. Yang et al.   JOURNAL OF IMMUNOLOGY

A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs

(2010) M. F. Denny et al.   JOURNAL OF IMMUNOLOGY

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preclinical Rheumatoid Arthritis: Identification, Evaluation, and Future Directions for Investigation

(2010) Kevin D. Deane et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Neutrophil function in inflammation and inflammatory diseases

(2010) H. L. Wright et al.   RHEUMATOLOGY

Absence of a classically activated macrophage cytokine signature in peripheral spondylarthritis, including psoriatic arthritis

(2009) Bernard Vandooren et al.   ARTHRITIS AND RHEUMATISM

The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases

(2009) John A. Hamilton et al.   ARTHRITIS AND RHEUMATISM

The role of innate immune responses in autoimmune disease development

(2009) Hanspeter Waldner   AUTOIMMUNITY REVIEWS

Surface RANKL of Toll-like receptor 4-stimulated human neutrophils activates osteoclastic bone resorption

(2009) A. Chakravarti et al.   BLOOD

Evidence for a cross-talk between human neutrophils and Th17 cells

(2009) M. Pelletier et al.   BLOOD

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

(2009) Noelia A-Gonzalez et al.   IMMUNITY

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

(2009) Andrew M. Smith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Extracellular Chromatin Release from Neutrophils

(2009) Indira Neeli et al.   Journal of Innate Immunity

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Genetics of Type 1A Diabetes

(2009) Patrick Concannon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism

(2008) M B Goldring et al.   ANNALS OF THE RHEUMATIC DISEASES

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis

(2008) J. L. Eyles et al.   BLOOD

Hematopoietic cytokines

(2008) D. Metcalf   BLOOD

The phagocytes: neutrophils and monocytes

(2008) D. C. Dale et al.   BLOOD

Migration across the sinusoidal endothelium regulates neutrophil mobilization in response to ELR + CXC chemokines

(2008) Peter C. E. Burdon et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk: Analysis of the Type 1 Diabetes Genetics Consortium Families

(2008) H. Erlich et al.   DIABETES

Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Rα, IL-13Rα1, and γc regulates relative cytokine sensitivity

(2008) Ilkka S. Junttila et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark

Regulation of B-cell-activating factor (BAFF)/B lymphocyte stimulator (BLyS) expression in human neutrophils

(2007) Patrizia Scapini et al.   IMMUNOLOGY LETTERS

A quantitative comparison of rates of phagocytosis and digestion of apoptotic cells by macrophages from normal (BALB/c) and diabetes-prone (NOD) mice

(2007) Athanasius F. M. Marée et al.   JOURNAL OF APPLIED PHYSIOLOGY

Single Residue Determines the Specificity of Neutrophil Elastase for Shigella Virulence Factors

(2007) Petra Averhoff et al.   JOURNAL OF MOLECULAR BIOLOGY

Tumor necrosis factor antagonist mechanisms of action: A comprehensive review

(2007) Daniel Tracey et al.   PHARMACOLOGY & THERAPEUTICS