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Title
Non-human primate models of PD to test novel therapies
Authors
Keywords
Non-human primate, Parkinson, Levodopa, Dyskinesia, Pharmacotherapy, MPTP
Journal
JOURNAL OF NEURAL TRANSMISSION
Volume 125, Issue 3, Pages 291-324
Publisher
Springer Nature
Online
2017-04-08
DOI
10.1007/s00702-017-1722-y
References
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Note: Only part of the references are listed.- Parkinson’s disease as a multisystem disorder
- (2017) Lisa Klingelhoefer et al. JOURNAL OF NEURAL TRANSMISSION
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- (2016) K. Kalinderi et al. ACTA NEUROLOGICA SCANDINAVICA
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- (2016) Marc Morissette et al. BIOCHEMICAL PHARMACOLOGY
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- (2009) Mélanie Bourque et al. FRONTIERS IN NEUROENDOCRINOLOGY
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- (2009) Jamie L. Eberling et al. HUMAN GENE THERAPY
- Clinically Relevant Effects of Convection-Enhanced Delivery of AAV2-GDNF on the Dopaminergic Nigrostriatal Pathway in Aged Rhesus Monkeys
- (2009) Louisa C. Johnston et al. HUMAN GENE THERAPY
- Safety Evaluation of AAV2-GDNF Gene Transfer into the Dopaminergic Nigrostriatal Pathway in Aged and Parkinsonian Rhesus Monkeys
- (2009) Xiaomin Su et al. HUMAN GENE THERAPY
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- (2009) J. Utikal et al. JOURNAL OF CELL SCIENCE
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- (2009) Xin Yang et al. JOURNAL OF GENE MEDICINE
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- (2009) L Alvarez et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Pathologic Modifications of α-Synuclein in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Squirrel Monkeys
- (2009) Alison L. McCormack et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
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- (2009) N. Liu et al. JOURNAL OF NEUROSCIENCE METHODS
- Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
- (2009) Dennis W Dickson et al. LANCET NEUROLOGY
- Diffusion tensor and perfusion MRI of non-human primates
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- No Lewy pathology in monkeys with over 10 years of severe MPTP Parkinsonism
- (2009) Glenda Halliday et al. MOVEMENT DISORDERS
- Generation of transgenic non-human primates with germline transmission
- (2009) Erika Sasaki et al. NATURE
- Medical Treatment of Parkinson Disease
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- Course in Parkinson disease subtypes: A 39-year clinicopathologic study
- (2009) A. H. Rajput et al. NEUROLOGY
- Safety and tolerability of putaminal AADC gene therapy for Parkinson disease
- (2009) C. W. Christine et al. NEUROLOGY
- Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: Common implication of striatal neuropeptides
- (2009) Mohamed Khalil Tamim et al. NEUROPHARMACOLOGY
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- (2009) Christopher D. Herzog et al. NEUROSURGERY
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- (2009) Anthony H.V. Schapira PARKINSONISM & RELATED DISORDERS
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- (2009) Laurent Grégoire et al. PARKINSONISM & RELATED DISORDERS
- Thalamic changes in Parkinson's disease
- (2009) Glenda M. Halliday PARKINSONISM & RELATED DISORDERS
- Dopamine Gene Therapy for Parkinson's Disease in a Nonhuman Primate Without Associated Dyskinesia
- (2009) B. Jarraya et al. Science Translational Medicine
- A critical evaluation of the Braak staging scheme for Parkinson's disease
- (2008) Robert E. Burke et al. ANNALS OF NEUROLOGY
- Tesofensine (NS 2330), a Monoamine Reuptake Inhibitor, in Patients With Advanced Parkinson Disease and Motor Fluctuations
- (2008) Olivier Rascol ARCHIVES OF NEUROLOGY
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- (2008) Gilbert Bensimon et al. BRAIN
- Enhancing Aromatic L-amino Acid Decarboxylase Activity: Implications for L-DOPA Treatment in Parkinson's Disease
- (2008) Maria Hadjiconstantinou et al. CNS Neuroscience & Therapeutics
- Dopamine agonists in Parkinson’s disease - focus on non-motor symptoms
- (2008) P. Jenner EUROPEAN JOURNAL OF NEUROLOGY
- Continuous delivery of ropinirole reverses motor deficits without dyskinesia induction in MPTP-treated common marmosets
- (2008) K.A. Stockwell et al. EXPERIMENTAL NEUROLOGY
- Implication of NMDA Receptors in the Antidyskinetic Activity of Cabergoline, CI-1041, and Ro 61-8048 in MPTP Monkeys with Levodopa-induced Dyskinesias
- (2008) Bazoumana Ouattara et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Dynamic Changes in the Cortex-Basal Ganglia Network After Dopamine Depletion in the Rat
- (2008) Cyril Dejean et al. JOURNAL OF NEUROPHYSIOLOGY
- Parkinsonian Beta Oscillations in the External Globus Pallidus and Their Relationship with Subthalamic Nucleus Activity
- (2008) N. Mallet et al. JOURNAL OF NEUROSCIENCE
- Quantitative evaluation of MPTP-treated nonhuman parkinsonian primates in the HALLWAY task
- (2008) Aurelio Campos-Romo et al. JOURNAL OF NEUROSCIENCE METHODS
- Non-dopaminergic treatments in development for Parkinson's disease
- (2008) Susan H Fox et al. LANCET NEUROLOGY
- Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
- (2008) William J Marks et al. LANCET NEUROLOGY
- Transgene Expression, Bioactivity, and Safety of CERE-120 (AAV2-Neurturin) Following Delivery to the Monkey Striatum
- (2008) Christopher D Herzog et al. MOLECULAR THERAPY
- Placebo influences on dyskinesia in Parkinson's disease
- (2008) Christopher G. Goetz et al. MOVEMENT DISORDERS
- Towards a transgenic model of Huntington’s disease in a non-human primate
- (2008) Shang-Hsun Yang et al. NATURE
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Molecular mechanisms of L-DOPA-induced dyskinesia
- (2008) Peter Jenner NATURE REVIEWS NEUROSCIENCE
- Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism
- (2008) t. chaumette et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Invited Article: Nervous system pathology in sporadic Parkinson disease
- (2008) H. Braak et al. NEUROLOGY
- Fourteen-year final report of the randomized PDRG-UK trial comparing three initial treatments in PD
- (2008) R. Katzenschlager et al. NEUROLOGY
- Results from a phase I safety trial of hAADC gene therapy for Parkinson disease
- (2008) J. L. Eberling et al. NEUROLOGY
- Lewy body pathology in long-term fetal nigral transplants: is parkinson's disease transmitted from one neural system to another?
- (2008) Jeffrey H Kordower et al. NEUROPSYCHOPHARMACOLOGY
- The 6-hydroxydopamine model: News from the past
- (2008) Fabio Blandini et al. PARKINSONISM & RELATED DISORDERS
- The association between motor subtypes and psychopathology in Parkinson's disease
- (2008) J.S.A.M. Reijnders et al. PARKINSONISM & RELATED DISORDERS
- Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys
- (2007) L GREGOIRE et al. BEHAVIOURAL BRAIN RESEARCH
- Beneficial effects of dietary omega-3 polyunsaturated fatty acid on toxin-induced neuronal degeneration in an animal model of Parkinson’s disease
- (2007) M. Bousquet et al. FASEB JOURNAL
- mGluR5 metabotropic glutamate receptors and dyskinesias in MPTP monkeys
- (2007) Pershia Samadi et al. NEUROBIOLOGY OF AGING
- Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson’s disease
- (2007) D.E. Redmond et al. NEUROBIOLOGY OF DISEASE
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