Improved Cell Therapy Protocols for Parkinson's Disease Based on Differentiation Efficiency and Safety of hESC-, hiPSC-, and Non-Human Primate iPSC-Derived Dopaminergic Neurons

Intracerebral Transplantation of Differentiated Human Embryonic Stem Cells to Hemiparkinsonian Monkeys

(2013) Marina E. Emborg et al.   CELL TRANSPLANTATION

Identification of embryonic stem cell–derived midbrain dopaminergic neurons for engraftment

(2012) Yosif M. Ganat et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease

(2012) O. Cooper et al.   Science Translational Medicine

Specification of Midbrain Dopamine Neurons from Primate Pluripotent Stem Cells

(2012) Jiajie Xi et al.   STEM CELLS

Prolonged Maturation Culture Favors a Reduction in the Tumorigenicity and the Dopaminergic Function of Human ESC-Derived Neural Cells in a Primate Model of Parkinson's Disease

(2012) Daisuke Doi et al.   STEM CELLS

Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions

(2012) Agnete Kirkeby et al.   Cell Reports

Immunogenicity of induced pluripotent stem cells

(2011) Tongbiao Zhao et al.   NATURE

Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A

(2011) Masataka Fujiwara et al.   PLoS One

Cell-Surface Marker Signatures for the Isolation of Neural Stem Cells, Glia and Neurons Derived from Human Pluripotent Stem Cells

(2011) Shauna H. Yuan et al.   PLoS One

Development of Histocompatible Primate-Induced Pluripotent Stem Cells for Neural Transplantation

(2011) Michela Deleidi et al.   STEM CELLS

Efficient Derivation of Functional Floor Plate Tissue from Human Embryonic Stem Cells

(2010) Christopher A. Fasano et al.   Cell Stem Cell

Markers of Pluripotency and Differentiation in Human Neural Precursor Cells Derived from Embryonic Stem Cells and CNS Tissue

(2010) M. Sundberg et al.   CELL TRANSPLANTATION

Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid

(2010) Oliver Cooper et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Epigenetic memory in induced pluripotent stem cells

(2010) K. Kim et al.   NATURE

Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

(2010) G. Hargus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Similarly derived and cultured hESC lines show variation in their developmental potential towards neuronal cells in long-term culture

(2010) Riikka S Lappalainen et al.   Regenerative Medicine

Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants

(2010) M. Politis et al.   Science Translational Medicine

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

(2009) Frank Soldner et al.   CELL

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

(2009) Hongyan Zhou et al.   Cell Stem Cell

Dopamine Cell Implantation in Parkinson's Disease: Long-Term Clinical and 18F-FDOPA PET Outcomes

(2009) Y. Ma et al.   JOURNAL OF NUCLEAR MEDICINE

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

(2009) Keisuke Kaji et al.   NATURE

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

(2009) Knut Woltjen et al.   NATURE

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

The blood–brain barrier is intact after levodopa-induced dyskinesias in parkinsonian primates—Evidence from in vivo neuroimaging studies

(2009) Arnar Astradsson et al.   NEUROBIOLOGY OF DISEASE

Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

(2009) J. Yu et al.   SCIENCE

Mitochondria: Determinants of Stem Cell Fate?

(2009) Graham C. Parker et al.   STEM CELLS AND DEVELOPMENT

Isolation and Production of Cells Suitable for Human Therapy: Challenges Ahead

(2008) Lars Ährlund-Richter et al.   Cell Stem Cell

CD marker expression profiles of human embryonic stem cells and their neural derivatives, determined using flow-cytometric analysis, reveal a novel CD marker for exclusion of pluripotent stem cells

(2008) Maria Sundberg et al.   Stem Cell Research

Embryonic Stem Cell-Derived Pitx3-Enhanced Green Fluorescent Protein Midbrain Dopamine Neurons Survive Enrichment by Fluorescence-Activated Cell Sorting and Function in an Animal Model of Parkinson's Disease

(2008) Eva Hedlund et al.   STEM CELLS