A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury

P2X1-regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration

(2016) Ramesh Kudira et al.   HEPATOLOGY

Therapeutic Role of Interleukin 22 in Experimental Intra-abdominal Klebsiella pneumoniae Infection in Mice

(2016) Mingquan Zheng et al.   INFECTION AND IMMUNITY

RORγt+ IL-22-producing NKp46+ cells protect from hepatic ischemia reperfusion injury in mice

(2016) Elke Eggenhofer et al.   JOURNAL OF HEPATOLOGY

Transcription Factor HIF-1α Controls Expression of the Cytokine IL-22 in CD4 T Cells

(2016) Scott A. Budda et al.   JOURNAL OF IMMUNOLOGY

Biological and pathological activities of interleukin-22

(2016) Mirna Perusina Lanfranca et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A pathogenic role for T cell–derived IL-22BP in inflammatory bowel disease

(2016) Penelope Pelczar et al.   SCIENCE

Up-regulation of interleukin-22 mediates liver fibrosis via activating hepatic stellate cells in patients with hepatitis C

(2015) Li-Yuan Wu et al.   CLINICAL IMMUNOLOGY

IL-22 and IL-22 binding protein (IL-22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections

(2015) Mathieu Sertorio et al.   HEPATOLOGY

IL-22BP is produced by eosinophils in human gut and blocks IL-22 protective actions during colitis

(2015) J C Martin et al.   Mucosal Immunology

Complementarity and redundancy of IL-22-producing innate lymphoid cells

(2015) Lucille C Rankin et al.   NATURE IMMUNOLOGY

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Plasmacytoid dendritic cell-derived IFN-α promotes murine liver ischemia/reperfusion injury by induction of hepatocyte IRF-1

(2014) Antonino Castellaneta et al.   HEPATOLOGY

Acute and Chronic Effects of IL-22 on Acetaminophen-Induced Liver Injury

(2014) Dechun Feng et al.   JOURNAL OF IMMUNOLOGY

Application of Interleukin-22 Mediates Protection in Experimental Acetaminophen-Induced Acute Liver Injury

(2013) Patrick Scheiermann et al.   AMERICAN JOURNAL OF PATHOLOGY

Pathological functions of interleukin-22 in chronic liver inflammation and fibrosis with hepatitis B virus infection by promoting T helper 17 cell recruitment

(2013) Juanjuan Zhao et al.   HEPATOLOGY

Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid

(2013) J CJ Martin et al.   Mucosal Immunology

Therapeutic opportunities of the IL-22–IL-22R1 system

(2013) Robert Sabat et al.   NATURE REVIEWS DRUG DISCOVERY

IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets

(2012) Malte Bachmann et al.   BIOCHEMICAL PHARMACOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study

(2012) Bernd Kronenberger et al.   BMC Medicine

Interleukin-22 Promotes Proliferation of Liver Stem/Progenitor Cells in Mice and Patients With Chronic Hepatitis B Virus Infection

(2012) Dechun Feng et al.   GASTROENTEROLOGY

IL-22 Promotes Fibroblast-Mediated Wound Repair in the Skin

(2012) Heather M. McGee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

(2012) Samuel Huber et al.   NATURE

Interleukin-22

(2012) Paul J. Chestovich et al.   TRANSPLANTATION

Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate-Adaptive Immune-Mediated Tissue Inflammation

(2011) Y. Zhai et al.   AMERICAN JOURNAL OF TRANSPLANTATION

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

A Proinflammatory Role for Interleukin-22 in the Immune Response to Hepatitis B Virus

(2011) Ye Zhang et al.   GASTROENTEROLOGY

In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression

(2011) Ogyi Park et al.   HEPATOLOGY

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

(2011) Samuel Huber et al.   IMMUNITY

Elevated Th22 Cells Correlated with Th17 Cells in Patients with Rheumatoid Arthritis

(2011) Lei Zhang et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Memory/effector (CD45RBlo) CD4 T cells are controlled directly by IL-10 and cause IL-22–dependent intestinal pathology

(2011) Masahito Kamanaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22

(2011) Gregory F Sonnenberg et al.   NATURE IMMUNOLOGY

Interleukin-22: A cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection

(2010) Ellen Witte et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3

(2010) Sung Hwan Ki et al.   HEPATOLOGY

Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion

(2010) Zubin M. Bamboat et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-22 Induces an Acute-Phase Response

(2010) S. C. Liang et al.   JOURNAL OF IMMUNOLOGY

IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-γ are not

(2009) Kerstin Wolk et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Mouse model of liver ischemia and reperfusion injury: method for studying reactive oxygen and nitrogen metabolites in vivo

(2008) Y ABE et al.   FREE RADICAL BIOLOGY AND MEDICINE

The importance of immune dysfunction in determining outcome in acute liver failure

(2008) Charalambos Gustav Antoniades et al.   JOURNAL OF HEPATOLOGY

Structure of IL-22 Bound to Its High-Affinity IL-22R1 Chain

(2008) Brandi C. Jones et al.   STRUCTURE