Platelets as autonomous drones for hemostatic and immune surveillance

The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors

(2017) Emma Lefrançais et al.   NATURE

A systems approach to hemostasis: 4. How hemostatic thrombi limit the loss of plasma-borne molecules from the microvasculature

(2016) J. D. Welsh et al.   BLOOD

Taking the stock of granule cargo: Platelet releasate proteomics

(2016) Oliver Pagel et al.   PLATELETS

Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response

(2016) Jan Rossaint et al.   Nature Communications

Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor

(2016) Wei Deng et al.   Nature Communications

Platelets Guide Leukocytes to Their Sites of Extravasation

(2016) Gabriele Zuchtriegel et al.   PLOS BIOLOGY

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

(2016) Xiaoyan Robert Bao et al.   eLife

Rupture Forces among Human Blood Platelets at different Degrees of Activation

(2016) Thi-Huong Nguyen et al.   Scientific Reports

Dengue virus binding and replication by platelets

(2015) A. Y. Simon et al.   BLOOD

Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice

(2015) A. Gros et al.   BLOOD

Platelet secretion: From haemostasis to wound healing and beyond

(2015) Ewelina M. Golebiewska et al.   BLOOD REVIEWS

Imaging the dynamic platelet-neutrophil response in sterile liver injury and repair in mice

(2015) Ingrid Slaba et al.   HEPATOLOGY

Platelet-neutrophil complex formation-a detailed in vitro analysis of murine and human blood samples

(2015) Maximilian Mauler et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Platelet secretory behaviour: as diverse as the granules … or not?

(2015) H. Heijnen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5

(2015) Jean-Eric Alard et al.   Science Translational Medicine

Poly (I:C) downregulates platelet production and function through type I interferon

(2015) Leonardo Rivadeneyra et al.   THROMBOSIS AND HAEMOSTASIS

The inflammatory role of platelets via their TLRs and Siglec receptors

(2015) Fabrice Cognasse   Frontiers in Immunology

Are Platelets Cells? And if Yes, are They Immune Cells?

(2015) Olivier Garraud et al.   Frontiers in Immunology

Platelet Mechanosensing of Collagen Matrices

(2015) Matthew F. Kee et al.   PLoS One

A tour through the transcriptional landscape of platelets

(2014) S. Schubert et al.   BLOOD

Emerging roles for platelets as immune and inflammatory cells

(2014) C. N. Morrell et al.   BLOOD

CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections

(2014) Nadja Bakocevic et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation

(2014) Adlen Foudi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation

(2014) Yongzhi Qiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophils scan for activated platelets to initiate inflammation

(2014) Vinatha Sreeramkumar et al.   SCIENCE

Phagocytosis by Thrombocytes is a Conserved Innate Immune Mechanism in Lower Vertebrates

(2014) Takahiro Nagasawa et al.   Frontiers in Immunology

Activated platelets can deliver mRNA regulatory Ago2bulletmicroRNA complexes to endothelial cells via microparticles

(2013) B. Laffont et al.   BLOOD

Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap-mediated sterile inflammation

(2013) J. Rossaint et al.   BLOOD

Circulating microparticles: square the circle

(2013) Natasha S Barteneva et al.   BMC CELL BIOLOGY

The complex transcriptional landscape of the anucleate human platelet

(2013) Paul F Bray et al.   BMC GENOMICS

The incredible journey: From megakaryocyte development to platelet formation

(2013) Kellie R. Machlus et al.   JOURNAL OF CELL BIOLOGY

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life

(2013) Paul R. Hess et al.   JOURNAL OF CLINICAL INVESTIGATION

Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

(2013) Brett H. Herzog et al.   NATURE

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

Platelet Granule Exocytosis: A Comparison with Chromaffin Cells

(2013) Jennifer L. Fitch-Tewfik et al.   Frontiers in Endocrinology

On the Origin of Microparticles: From “Platelet Dust” to Mediators of Intercellular Communication

(2013) Leslie A. Hargett et al.   Pulmonary Circulation

Blood Clots Are Rapidly Assembled Hemodynamic Sensors

(2012) Ryan W. Muthard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelets and platelet-like particles mediate intercellular RNA transfer

(2012) A. Risitano et al.   BLOOD

Platelets can enhance vascular permeability

(2012) N. Cloutier et al.   BLOOD

Human platelets can discriminate between various bacterial LPS isoforms via TLR4 signaling and differential cytokine secretion

(2012) Julien Berthet et al.   CLINICAL IMMUNOLOGY

Platelet Activation Receptor CLEC-2 Regulates Blood/Lymphatic Vessel Separation by Inhibiting Proliferation, Migration, and Tube Formation of Lymphatic Endothelial Cells

(2012) Makoto Osada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Purinergic Signaling during Inflammation

(2012) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Platelet Factor 4 and Duffy Antigen Required for Platelet Killing of Plasmodium falciparum

(2012) B. J. McMorran et al.   SCIENCE

Quantitative immunofluorescence mapping reveals little functional coclustering of proteins within platelet  -granules

(2011) J. Kamykowski et al.   BLOOD

Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular disease

(2011) A. A. Schmaier et al.   BLOOD

Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes

(2011) J. W. Rowley et al.   BLOOD

How platelets safeguard vascular integrity

(2011) B. HO-TIN-NOÉ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Monocyte-Platelet Interaction Induces a Pro-Inflammatory Phenotype in Circulating Monocytes

(2011) Gabriella Passacquale et al.   PLoS One

Clinical relevance of microparticles from platelets and megakaryocytes

(2010) Joseph E Italiano et al.   CURRENT OPINION IN HEMATOLOGY

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet α-granules: Basic biology and clinical correlates

(2009) Price Blair et al.   BLOOD REVIEWS

The platelet as an immune cell—CD40 ligand and transfusion immunomodulation

(2009) Neil Blumberg et al.   IMMUNOLOGIC RESEARCH

Comparative Morphology, Development, and Function of Blood Cells in Nonmammalian Vertebrates

(2009) Juan A. Claver et al.   Journal of Exotic Pet Medicine

Dual roles for hepatic lectin receptors in the clearance of chilled platelets

(2009) Viktoria Rumjantseva et al.   NATURE MEDICINE

Platelets Kill Intraerythrocytic Malarial Parasites and Mediate Survival to Infection

(2009) B. J. McMorran et al.   SCIENCE

Novel and unexpected clearance mechanisms for cold platelets

(2009) Viktoria Rumjantseva et al.   TRANSFUSION AND APHERESIS SCIENCE

Genome size, cell size, and the evolution of enucleated erythrocytes in attenuate salamanders

(2008) Rachel Lockridge Mueller et al.   ZOOLOGY