Taking the stock of granule cargo: Platelet releasate proteomics

Simultaneous Metabolite, Protein, Lipid Extraction (SIMPLEX): A Combinatorial Multimolecular Omics Approach for Systems Biology

(2016) Cristina Coman et al.   MOLECULAR & CELLULAR PROTEOMICS

Parallel reaction monitoring using quadrupole-Orbitrap mass spectrometer: Principle and applications

(2016) Adele Bourmaud et al.   PROTEOMICS

Evaluating Multiplexed Quantitative Phosphopeptide Analysis on a Hybrid Quadrupole Mass Filter/Linear Ion Trap/Orbitrap Mass Spectrometer

(2015) Brian K. Erickson et al.   ANALYTICAL CHEMISTRY

Highly Sensitive Phosphoproteomics by Tailoring Solid-Phase Extraction to Electrostatic Repulsion-Hydrophilic Interaction Chromatography

(2015) Stefan Loroch et al.   ANALYTICAL CHEMISTRY

Platelet-Associated Matrix Metalloproteinases Regulate Thrombus Formation and Exert Local Collagenolytic ActivitySignificance

(2015) Tom G. Mastenbroek et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet geometry sensing spatially regulates  -granule secretion to enable matrix self-deposition

(2015) Y. Sakurai et al.   BLOOD

Platelet secretion: From haemostasis to wound healing and beyond

(2015) Ewelina M. Golebiewska et al.   BLOOD REVIEWS

Current strategies and findings in clinically relevant post-translational modification-specific proteomics

(2015) Oliver Pagel et al.   Expert Review of Proteomics

Platelet serotonin modulates immune functions

(2015) M. Mauler et al.   Hamostaseologie

Quantitative proteome analysis of Caenorhabditis elegans upon exposure to nematicidal Bacillus thuringiensis

(2015) Christian Treitz et al.   Journal of Proteomics

Differences in the resting platelet proteome and platelet releasate between healthy children and adults

(2015) Charmaine Cini et al.   Journal of Proteomics

Spatiotemporal regulation of coagulation and platelet activation during the hemostatic responsein vivo

(2015) L. Ivanciu et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Multiple Reaction Monitoring Enables Precise Quantification of 97 Proteins in Dried Blood Spots

(2015) Andrew G. Chambers et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantitation with chemical tagging reagents in biomarker studies

(2015) Jules A. Westbrook et al.   Proteomics Clinical Applications

Recent advances in targeted proteomics for clinical applications

(2015) Bruno Domon et al.   Proteomics Clinical Applications

Is label-free LC-MS/MS ready for biomarker discovery?

(2015) Marianne Sandin et al.   Proteomics Clinical Applications

A 2D-DIGE-based proteomic analysis reveals differences in the platelet releasate composition when comparing thrombin and collagen stimulations

(2015) Paula Vélez et al.   Scientific Reports

Supporting Roles of Platelet Thrombospondin-1 and CD36 in Thrombus Formation on Collagen

(2014) Marijke J.E. Kuijpers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Quantitative proteomics analysis reveals similar release profiles following specific PAR-1 or PAR-4 stimulation of platelets

(2014) Thijs C. van Holten et al.   CARDIOVASCULAR RESEARCH

Microvesicles as Cell–Cell Messengers in Cardiovascular Diseases

(2014) Xavier Loyer et al.   CIRCULATION RESEARCH

Single-step Enrichment by Ti4+-IMAC and Label-free Quantitation Enables In-depth Monitoring of Phosphorylation Dynamics with High Reproducibility and Temporal Resolution

(2014) Erik L. de Graaf et al.   MOLECULAR & CELLULAR PROTEOMICS

Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach

(2014) Steven A. Carr et al.   MOLECULAR & CELLULAR PROTEOMICS

Mass spectrometry based biomarker discovery, verification, and validation - Quality assurance and control of protein biomarker assays

(2014) Carol E. Parker et al.   Molecular Oncology

Platelets: at the nexus of antimicrobial defence

(2014) Michael R. Yeaman   NATURE REVIEWS MICROBIOLOGY

High Precision Platelet Releasate Definition by Quantitative Reversed Protein Profiling—Brief Report

(2013) Patrick Wijten et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Biomarkers for prediction of venous thromboembolism in cancer

(2013) I. Pabinger et al.   BLOOD

Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation

(2013) E. D. Hottz et al.   BLOOD

Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways

(2013) F. Beck et al.   BLOOD

Novel Highly Sensitive, Specific, and Straightforward Strategy for Comprehensive N-Terminal Proteomics Reveals Unknown Substrates of the Mitochondrial Peptidase Icp55

(2013) A. Saskia Venne et al.   JOURNAL OF PROTEOME RESEARCH

Platelet-derived CXCL12 (SDF-1α): basic mechanisms and clinical implications

(2013) M. Chatterjee et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Deciphering of ADP-induced, phosphotyrosine-dependent signaling networks in human platelets by Src-homology 2 region (SH2)-profiling

(2013) Hardy Schweigel et al.   PROTEOMICS

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways

(2012) J. M. Burkhart et al.   BLOOD

Granule exocytosis is required for platelet spreading: differential sorting of  -granules expressing VAMP-7

(2012) C. G. Peters et al.   BLOOD

Platelet secretion is kinetically heterogeneous in an agonist-responsive manner

(2012) D. Jonnalagadda et al.   BLOOD

T granules in human platelets function in TLR9 organization and signaling

(2012) Jonathan N. Thon et al.   JOURNAL OF CELL BIOLOGY

TiSH — a robust and sensitive global phosphoproteomics strategy employing a combination of TiO2, SIMAC, and HILIC

(2012) Kasper Engholm-Keller et al.   Journal of Proteomics

Human neutrophil alpha-defensins induce formation of fibrinogen and thrombospondin-1 amyloid-like structures and activate platelets via glycoprotein IIb/IIIa

(2012) M. HORN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet-Derived Microvesicles: Multitalented Participants in Intercellular Communication

(2012) Maria Aatonen et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Quantitative immunofluorescence mapping reveals little functional coclustering of proteins within platelet  -granules

(2011) J. Kamykowski et al.   BLOOD

Platelet granules: surprise packages

(2011) S. W. Whiteheart   BLOOD

Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis

(2011) E. M. Battinelli et al.   BLOOD

Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli

(2011) M. Chatterjee et al.   BLOOD

The role of platelets in defence against pathogens

(2011) K. J. Clemetson   Hamostaseologie

An integrated proteomics and genomics analysis to unravel a heterogeneous platelet secretion defect

(2011) Michela Di Michele et al.   Journal of Proteomics

Extracellular protein disulfide isomerase regulates feedback activation of platelet thrombin generation via modulation of coagulation factor binding

(2011) K. JURK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

NBEAL2 is mutated in gray platelet syndrome and is required for biogenesis of platelet α-granules

(2011) Meral Gunay-Aygun et al.   NATURE GENETICS

Deciphering the human platelet sheddome

(2010) K. P. Fong et al.   BLOOD

Proteomics Strategy for Identifying Candidate Bioactive Proteins in Complex Mixtures: Application to the Platelet Releasate

(2010) Roisin O'Connor et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

The α-granule proteome: novel proteins in normal and ghost granules in gray platelet syndrome

(2010) D. M. MAYNARD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The platelet contribution to cancer progression

(2010) N. M. BAMBACE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Novel integrin-dependent platelet malfunction in siblings with leukocyte adhesion deficiency-III (LAD-III) caused by a point mutation in FERMT3

(2010) Kerstin Jurk et al.   THROMBOSIS AND HAEMOSTASIS

Preparation of monodisperse immobilized Ti4+ affinity chromatography microspheres for specific enrichment of phosphopeptides

(2009) Zhiyuan Yu et al.   ANALYTICA CHIMICA ACTA

Lys-N and Trypsin Cover Complementary Parts of the Phosphoproteome in a Refined SCX-Based Approach

(2009) Sharon Gauci et al.   ANALYTICAL CHEMISTRY

Platelet protein disulfide isomerase is localized in the dense tubular system and does not become surface expressed after activation

(2009) H. E. van Nispen tot Pannerden et al.   BLOOD

Platelet α-granules: Basic biology and clinical correlates

(2009) Price Blair et al.   BLOOD REVIEWS

Tissue inhibitors of matrix metalloproteinases in platelets and megakaryocytes: A novel organization for these secreted proteins

(2009) Julien Villeneuve et al.   EXPERIMENTAL HEMATOLOGY

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

(2009) Rory R Koenen et al.   NATURE MEDICINE

Role of the platelet chemokine platelet factor 4 (PF4) in hemostasis and thrombosis

(2009) M. Anna Kowalska et al.   THROMBOSIS RESEARCH

Platelet Chemokines in Vascular Disease

(2008) Christian A. Gleissner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proteomics of the TRAP-induced platelet releasate

(2008) Sander R. Piersma et al.   Journal of Proteomics

Application of 2-dimensional difference gel electrophoresis (2D-DIGE) to the study of thrombin-activated human platelet secretome

(2008) Anna Della Corte et al.   PLATELETS

Electrostatic Repulsion Hydrophilic Interaction Chromatography for Isocratic Separation of Charged Solutes and Selective Isolation of Phosphopeptides

(2007) Andrew J. Alpert   ANALYTICAL CHEMISTRY