Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone inC. elegans

NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans

(2017) Collin Yvès Ewald et al.   eLife

Antioxidants reveal an inverted U-shaped dose-response relationship between reactive oxygen species levels and the rate of aging inCaenorhabditis elegans

(2016) David Desjardins et al.   AGING CELL

Repression of the Antioxidant NRF2 Pathway in Premature Aging

(2016) Nard Kubben et al.   CELL

Pyrroloquinoline quinone enhances the resistance to oxidative stress and extends lifespan upon DAF-16 and SKN-1 activities in C. elegans

(2016) J.Z. Wu et al.   EXPERIMENTAL GERONTOLOGY

Roles for ROS and hydrogen sulfide in the longevity response to germline loss inCaenorhabditis elegans

(2016) Yuehua Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis

(2016) Jorge Iván Castillo-Quan et al.   Cell Reports

Recent progress in studies on the health benefits of pyrroloquinoline quinone

(2015) Mitsugu Akagawa et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

ROS-dependent signal transduction

(2015) Colleen R Reczek et al.   CURRENT OPINION IN CELL BIOLOGY

SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans

(2015) T. Keith Blackwell et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial dysfunction and longevity in animals: Untangling the knot

(2015) Y. Wang et al.   SCIENCE

Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan

(2015) Claire E. Schaar et al.   PLoS Genetics

Localization of the Dual Oxidase BLI-3 and Characterization of Its NADPH Oxidase Domain during Infection of Caenorhabditis elegans

(2015) Ransome van der Hoeven et al.   PLoS One

The Intrinsic Apoptosis Pathway Mediates the Pro-Longevity Response to Mitochondrial ROS in C. elegans

(2014) Callista Yee et al.   CELL

Mitohormesis

(2014) Jeanho Yun et al.   Cell Metabolism

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Tetraspanins at a glance

(2014) S. Charrin et al.   JOURNAL OF CELL SCIENCE

Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity

(2014) Collin Y. Ewald et al.   NATURE

Unraveling the Truth About Antioxidants: Mitohormesis explains ROS-induced health benefits

(2014) Michael Ristow   NATURE MEDICINE

Unraveling the Truth About Antioxidants: ROS and disease: finding the right balance

(2014) Hiroyuki Kawagishi et al.   NATURE MEDICINE

Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity inCaenorhabditis elegans

(2014) Ara B. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

D-Glucosamine supplementation extends life span of nematodes and of ageing mice

(2014) Sandra Weimer et al.   Nature Communications

The BLI-3/TSP-15/DOXA-1 Dual Oxidase Complex Is Required for Iodide Toxicity in Caenorhabditis elegans

(2014) Zhaofa Xu et al.   G3-Genes Genomes Genetics

Bacteria and the Aging and Longevity of Caenorhabditis elegans

(2013) Dennis H. Kim   Annual Review of Genetics

Roles of DUOX-Mediated Hydrogen Peroxide in Metabolism, Host Defense, and Signaling

(2013) Xavier De Deken et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive oxygen species, ageing and the hormesis police

(2013) Paula Ludovico et al.   FEMS YEAST RESEARCH

The Myth of Antioxidants

(2013) Melinda Wenner Moyer   SCIENTIFIC AMERICAN

A cytoprotective perspective on longevity regulation

(2013) David E. Shore et al.   TRENDS IN CELL BIOLOGY

A Fasting-Responsive Signaling Pathway that Extends Life Span in C. elegans

(2013) Masaharu Uno et al.   Cell Reports

The Caenorhabditis elegans JNK Signaling Pathway Activates Expression of Stress Response Genes by Derepressing the Fos/HDAC Repressor Complex

(2013) Ayuna Hattori et al.   PLoS Genetics

Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?

(2012) David Gems et al.   ANTIOXIDANTS & REDOX SIGNALING

Increased Levels of Hydrogen Peroxide Induce a HIF-1-dependent Modification of Lipid Metabolism in AMPK Compromised C. elegans Dauer Larvae

(2012) Meng Xie et al.   Cell Metabolism

Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal

(2012) Kim Zarse et al.   Cell Metabolism

Crystal structure and characterization of pyrroloquinoline quinone disodium trihydrate

(2012) Kazuto Ikemoto et al.   Chemistry Central Journal

The role of the gut microbiota in nutrition and health

(2012) Harry J. Flint et al.   Nature Reviews Gastroenterology & Hepatology

Tetraspanin Is Required for Generation of Reactive Oxygen Species by the Dual Oxidase System in Caenorhabditis elegans

(2012) Hiroki Moribe et al.   PLoS Genetics

Cellular stress response pathways and ageing: intricate molecular relationships

(2011) Nikos Kourtis et al.   EMBO JOURNAL

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

(2011) William Mair et al.   NATURE

Extension of Lifespan in C. elegans by Naphthoquinones That Act through Stress Hormesis Mechanisms

(2011) Piper R. Hunt et al.   PLoS One

Ce-Duox1/BLI-3 Generated Reactive Oxygen Species Trigger Protective SKN-1 Activity via p38 MAPK Signaling during Infection in C. elegans

(2011) Ransome van der Hoeven et al.   PLoS Pathogens

Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans

(2010) Wen Yang et al.   AGING CELL

Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity

(2010) Seung-Jae Lee et al.   CURRENT BIOLOGY

Functional Consequences of Dual Oxidase-Thyroperoxidase Interaction at the Plasma Membrane

(2010) Rodrigo Soares Fortunato et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

A Peroxidase/Dual Oxidase System Modulates Midgut Epithelial Immunity in Anopheles gambiae

(2010) S. Kumar et al.   SCIENCE

The rise of antioxidant signaling—The evolution and hormetic actions of Nrf2

(2010) Jonathan Maher et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

(2010) Wen Yang et al.   PLOS BIOLOGY

Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1

(2009) Sang-Kyu Park et al.   AGING CELL

Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis

(2009) Kai Hartwig et al.   Genes and Nutrition

Ce-Duox1/BLI-3 Generates Reactive Oxygen Species as a Protective Innate Immune Mechanism in Caenorhabditis elegans

(2009) V. Chavez et al.   INFECTION AND IMMUNITY

Combined Extracellular Matrix Cross-linking Activity of the Peroxidase MLT-7 and the Dual Oxidase BLI-3 Is Critical for Post-embryonic Viability inCaenorhabditis elegans

(2009) Melanie C. Thein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells

(2009) S. Luxen et al.   JOURNAL OF CELL SCIENCE

DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses

(2009) S. Lipinski et al.   JOURNAL OF CELL SCIENCE

Association of Duoxes with Thyroid Peroxidase and Its Regulation in Thyrocytes

(2009) Yue Song et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone

(2009) Aaron J. Przybysz et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Caenorhabditis elegans FOS-1 and JUN-1 Regulate plc-1 Expression in the Spermatheca to Control Ovulation

(2009) Susan M. Hiatt et al.   MOLECULAR BIOLOGY OF THE CELL

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Measuring Caenorhabditis elegans Life Span on Solid Media

(2009) George L. Sutphin et al.   Jove-Journal of Visualized Experiments

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

(2008) Jennifer M.A. Tullet et al.   CELL

Stress-Response Hormesis and Aging: “That which Does Not Kill Us Makes Us Stronger”

(2008) David Gems et al.   Cell Metabolism

Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation

(2008) Stanislas Morand et al.   FASEB JOURNAL

Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species

(2008) Hideki Sumimoto   FEBS Journal

Clustering of Genetically Defined Allele Classes in the Caenorhabditis elegans DAF-2 Insulin/IGF-1 Receptor

(2008) D. S. Patel et al.   GENETICS

Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans

(2008) Sakiko Honjoh et al.   NATURE