Roles of DUOX-Mediated Hydrogen Peroxide in Metabolism, Host Defense, and Signaling
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Title
Roles of DUOX-Mediated Hydrogen Peroxide in Metabolism, Host Defense, and Signaling
Authors
Keywords
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Journal
ANTIOXIDANTS & REDOX SIGNALING
Volume 20, Issue 17, Pages 2776-2793
Publisher
Mary Ann Liebert Inc
Online
2013-09-08
DOI
10.1089/ars.2013.5602
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Note: Only part of the references are listed.- The Pseudomonas Toxin Pyocyanin Inhibits the Dual Oxidase-Based Antimicrobial System as It Imposes Oxidative Stress on Airway Epithelial Cells
- (2014) B. Rada et al. JOURNAL OF IMMUNOLOGY
- IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH Oxidase-mediated airway antiviral response
- (2013) Karin Fink et al. CELL RESEARCH
- Calcium Flashes Orchestrate the Wound Inflammatory Response through DUOX Activation and Hydrogen Peroxide Release
- (2013) William Razzell et al. CURRENT BIOLOGY
- Recent Insights into the Cell Biology of Thyroid Angiofollicular Units
- (2013) Ides M. Colin et al. ENDOCRINE REVIEWS
- NADPH Oxidase Biology and the Regulation of Tyrosine Kinase Receptor Signaling and Cancer Drug Cytotoxicity
- (2013) Rafael Paletta-Silva et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody
- (2013) YONGHZONG WU et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Conserved Cysteine Residues Provide a Protein-Protein Interaction Surface in Dual Oxidase (DUOX) Proteins
- (2013) Jennifer L. Meitzler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of TLR4 Is Required for the Synergistic Induction of Dual Oxidase 2 and Dual Oxidase A2 by IFN- and Lipopolysaccharide in Human Pancreatic Cancer Cell Lines
- (2013) Y. Wu et al. JOURNAL OF IMMUNOLOGY
- Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration
- (2013) Nick R. Love et al. NATURE CELL BIOLOGY
- ATP-Mediated Transactivation of the Epidermal Growth Factor Receptor in Airway Epithelial Cells Involves DUOX1-Dependent Oxidation of Src and ADAM17
- (2013) Derek Sham et al. PLoS One
- The Role of Reactive Oxygen Species in Anopheles aquasalis Response to Plasmodium vivax Infection
- (2013) Ana C. Bahia et al. PLoS One
- Iron Status and Its Determinants in a Nationally Representative Sample of Pregnant Women
- (2013) Stefanie Vandevijvere et al. Journal of the Academy of Nutrition and Dietetics
- Dual Oxidase 2 Bidirectional Promoter Polymorphisms Confer Differential Immune Responses in Airway Epithelia
- (2012) Changhong Xu et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Dual Oxidase–1 Is Required for Airway Epithelial Cell Migration and Bronchiolar Reepithelialization after Injury
- (2012) Stefan H. Gorissen et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Spatial and Temporal Analysis of NADPH Oxidase-Generated Hydrogen Peroxide Signals by Novel Fluorescent Reporter Proteins
- (2012) Balázs Enyedi et al. ANTIOXIDANTS & REDOX SIGNALING
- Redox Regulation of Epidermal Growth Factor Receptor Signaling through Cysteine Oxidation
- (2012) Thu H. Truong et al. BIOCHEMISTRY
- Neutrophil-Delivered Myeloperoxidase Dampens the Hydrogen Peroxide Burst after Tissue Wounding in Zebrafish
- (2012) Luke Pase et al. CURRENT BIOLOGY
- The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA
- (2012) Candice Hoste et al. EXPERIMENTAL CELL RESEARCH
- Expression of lactoperoxidase in differentiated mouse colon epithelial cells
- (2012) Byung-Wook Kim et al. FREE RADICAL BIOLOGY AND MEDICINE
- Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2and its maturation factorDUOXA2
- (2012) Houssam Raad et al. FREE RADICAL BIOLOGY AND MEDICINE
- NIP/DuoxA is essential for Drosophila embryonic development and regulates oxidative stress response
- (2012) Xiaojun Xie et al. International Journal of Biological Sciences
- A novel dual oxidase maturation factor 2 gene mutation for congenital hypothyroidism
- (2012) RU-HAI YI et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish
- (2012) Sa Kan Yoo et al. JOURNAL OF CELL BIOLOGY
- Congenital hypothyroidism caused by a novel mutation of the dual oxidase 2 (DUOX2) gene
- (2012) Atsuko Yoshizawa-Ogasawara et al. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
- Functional inactivation of thyroid transcription factor-1 in PCCl3 thyroid cells
- (2012) Christiane Christophe-Hobertus et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Mice Deficient in Dual Oxidase Maturation Factors Are Severely Hypothyroid
- (2012) Helmut Grasberger et al. MOLECULAR ENDOCRINOLOGY
- Reactive Oxygen Species Regulate the Levels of Dual Oxidase (Duox1-2) in Human Neuroblastoma Cells
- (2012) Simona Damiano et al. PLoS One
- Analysis of Candidate Colitis Genes in the Gdac1 Locus of Mice Deficient in Glutathione Peroxidase-1 and -2
- (2012) R. Steven Esworthy et al. PLoS One
- mRNA Expression in Papillary and Anaplastic Thyroid Carcinoma: Molecular Anatomy of a Killing Switch
- (2012) Aline Hébrant et al. PLoS One
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- (2012) Geneviève Dom et al. THYROID
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- (2012) Akira Kawashima et al. THYROID
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- (2012) Do-Yeon Cho et al. International Forum of Allergy & Rhinology
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- (2012) Hiroki Moribe et al. PLoS Genetics
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- (2011) Lifen Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
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- (2011) Anthony J. Fischer et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
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- Cell biology of H2O2 generation in the thyroid: Investigation of the control of dual oxidases (DUOX) activity in intact ex vivo thyroid tissue and cell lines
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- TSH Receptor Function Is Required for Normal Thyroid Differentiation in Zebrafish
- (2011) Robert Opitz et al. MOLECULAR ENDOCRINOLOGY
- Lyn is a redox sensor that mediates leukocyte wound attraction in vivo
- (2011) Sa Kan Yoo et al. NATURE
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- (2011) Can-Liang Lu et al. TUMOR BIOLOGY
- Hydrogen Peroxide Promotes Injury-Induced Peripheral Sensory Axon Regeneration in the Zebrafish Skin
- (2011) Sandra Rieger et al. PLOS BIOLOGY
- Duox, Flotillin-2, and Src42A Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in Drosophila
- (2011) Michelle T. Juarez et al. PLoS Genetics
- Blood Meal-Derived Heme Decreases ROS Levels in the Midgut of Aedes aegypti and Allows Proliferation of Intestinal Microbiota
- (2011) Jose Henrique M. Oliveira et al. PLoS Pathogens
- All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium
- (2010) Angela Lee Linderholm et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- IFNγ mediates DUOX2 expression via a STAT-independent signaling pathway
- (2010) Thomas Hill et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties
- (2010) Maria Vega Flores et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Stimulation by P2X7 receptors of calcium-dependent production of reactive oxygen species (ROS) in rat submandibular glands
- (2010) U. Fontanils et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Role of H2O2 in RET/PTC1 Chromosomal Rearrangement Produced by Ionizing Radiation in Human Thyroid Cells
- (2010) R. Ameziane-El-Hassani et al. CANCER RESEARCH
- RETRACTED: REDOX regulation of IL-13 signaling in intestinal epithelial cells: Usage of alternate pathways mediates distinct gene expression patterns
- (2010) Debasmita Mandal et al. CELLULAR SIGNALLING
- Prioritization of Competing Damage and Developmental Signals by Migrating Macrophages in the Drosophila Embryo
- (2010) Severina Moreira et al. CURRENT BIOLOGY
- Topographical distribution of antimicrobial genes in the zebrafish intestine
- (2010) Stefan H. Oehlers et al. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
- Urothelial cells produce hydrogen peroxide through the activation of Duox1
- (2010) Ágnes Donkó et al. FREE RADICAL BIOLOGY AND MEDICINE
- Compound heterozygosity for a novel hemizygous missense mutation and a partial deletion affecting the catalytic core of the H2O2-generating enzyme DUOX2 associated with transient congenital hypothyroidism
- (2010) Candice Hoste et al. HUMAN MUTATION
- Mammalian Numb-interacting Protein 1/Dual Oxidase Maturation Factor 1 Directs Neuronal Fate in Stem Cells
- (2010) Karen A. M. Kennedy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Perturbed Heme Binding Is Responsible for the Blistering Phenotype Associated with Mutations in theCaenorhabditis elegansDual Oxidase 1 (DUOX1) Peroxidase Domain
- (2010) Jennifer L. Meitzler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional Consequences of Dual Oxidase-Thyroperoxidase Interaction at the Plasma Membrane
- (2010) Rodrigo Soares Fortunato et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Double-Stranded RNA Induces Shedding of the 34-kDa Soluble TNFR1 from Human Airway Epithelial Cells via TLR3-TRIF-RIP1-Dependent Signaling: Roles for Dual Oxidase 2- and Caspase-Dependent Pathways
- (2010) M. Yu et al. JOURNAL OF IMMUNOLOGY
- Delimitation and functional characterization of the bidirectional THOX–DUOXA promoter regions in thyrocytes
- (2010) Christiane Christophe-Hobertus et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Genetics and phenomics of hypothyroidism and goiter due to TPO mutations
- (2010) Carrie Ris-Stalpers et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Defects of thyroidal hydrogen peroxide generation in congenital hypothyroidism
- (2010) Helmut Grasberger MOLECULAR AND CELLULAR ENDOCRINOLOGY
- NF-κB p65 Subunit Mediates Lipopolysaccharide-Induced Na+/I−Symporter Gene Expression by Involving Functional Interaction with the Paired Domain Transcription Factor Pax8
- (2010) Juan Pablo Nicola et al. MOLECULAR ENDOCRINOLOGY
- Lipid Rafts As a Membrane-Organizing Principle
- (2010) D. Lingwood et al. SCIENCE
- A Peroxidase/Dual Oxidase System Modulates Midgut Epithelial Immunity in Anopheles gambiae
- (2010) S. Kumar et al. SCIENCE
- The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling
- (2010) J. Kwon et al. Science Signaling
- Dual oxidase in mucosal immunity and host–microbe homeostasis
- (2010) Yun Soo Bae et al. TRENDS IN IMMUNOLOGY
- Mechanisms and Function of DUOX in Epithelia of the Lung
- (2009) Horst Fischer ANTIOXIDANTS & REDOX SIGNALING
- Targeting and Regulation of Reactive Oxygen Species Generation by Nox Family NADPH Oxidases
- (2009) Thomas L. Leto et al. ANTIOXIDANTS & REDOX SIGNALING
- NIP1/DUOXA1 expression in epithelial breast cancer cells: regulation of cell adhesion and actin dynamics
- (2009) Elena A. Ostrakhovitch et al. BREAST CANCER RESEARCH AND TREATMENT
- Hydrogen peroxide induces DNA single- and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ
- (2009) Natacha Driessens et al. ENDOCRINE-RELATED CANCER
- Oxidative epithelial host defense is regulated by infectious and inflammatory stimuli
- (2009) Monica Valencia Gattas et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ce-Duox1/BLI-3 Generates Reactive Oxygen Species as a Protective Innate Immune Mechanism in Caenorhabditis elegans
- (2009) V. Chavez et al. INFECTION AND IMMUNITY
- ATP-mediated Activation of the NADPH Oxidase DUOX1 Mediates Airway Epithelial Responses to Bacterial Stimuli
- (2009) Agnes W. Boots et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Caenorhabditis elegansand Human Dual Oxidase 1 (DUOX1) “Peroxidase” Domains
- (2009) Jennifer L. Meitzler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Combined Extracellular Matrix Cross-linking Activity of the Peroxidase MLT-7 and the Dual Oxidase BLI-3 Is Critical for Post-embryonic Viability inCaenorhabditis elegans
- (2009) Melanie C. Thein et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of Dual Oxidases Duox1 and Duox2
- (2009) Sabrina Rigutto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells
- (2009) S. Luxen et al. JOURNAL OF CELL SCIENCE
- DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses
- (2009) S. Lipinski et al. JOURNAL OF CELL SCIENCE
- Association of Duoxes with Thyroid Peroxidase and Its Regulation in Thyrocytes
- (2009) Yue Song et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- NADPH Oxidase 2 Interaction with TLR2 Is Required for Efficient Innate Immune Responses to Mycobacteria via Cathelicidin Expression
- (2009) C.-S. Yang et al. JOURNAL OF IMMUNOLOGY
- Potential role of Noxes in the protection of mucosae: H2O2 as abacterial repellent
- (2009) A. Botteaux et al. MICROBES AND INFECTION
- A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
- (2009) Philipp Niethammer et al. NATURE
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- (2009) Abdelmounaaïm Allaoui et al. TRENDS IN MOLECULAR MEDICINE
- Implication of the Mosquito Midgut Microbiota in the Defense against Malaria Parasites
- (2009) Yuemei Dong et al. PLoS Pathogens
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- (2008) Jonathan L. Koff et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
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- (2008) Ina Helmcke et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2008) S. Luxen et al. CANCER RESEARCH
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- (2008) Sylvie Poncin et al. ENDOCRINOLOGY
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- (2008) Stanislas Morand et al. FASEB JOURNAL
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- (2008) Pankaj Sharma et al. IMMUNITY
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- (2008) Sandrine Pacquelet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Yoshihiro Maruo et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2008) Eric Ogier-Denis et al. Seminars in Immunopathology
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- (2007) Ilaria Zamproni et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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