Alternative Pre-mRNA Splicing in Mammals and Teleost Fish: A Effective Strategy for the Regulation of Immune Responses Against Pathogen Infection

Characterization and expression profiling of NOD-like receptor C3 (NLRC3) in mucosal tissues of turbot ( Scophthalmus maximus L.) following bacterial challenge

(2017) Zhumei Hou et al.   FISH & SHELLFISH IMMUNOLOGY

The antiviral signaling mediated by black carp MDA5 is positively regulated by LGP2

(2017) Ji Liu et al.   FISH & SHELLFISH IMMUNOLOGY

Molecular cloning of MDA5, phylogenetic analysis of RIG-I-like receptors (RLRs) and differential gene expression of RLRs, interferons and proinflammatory cytokines after in vitro challenge with IPNV, ISAV and SAV in the salmonid cell line TO

(2017) I-K G Nerbøvik et al.   JOURNAL OF FISH DISEASES

Insights into the diversity of NOD-like receptors: Identification and expression analysis of NLRC3, NLRC5 and NLRX1 in rainbow trout

(2017) Claudio A. Álvarez et al.   MOLECULAR IMMUNOLOGY

NOD1 deficiency impairs CD44a/Lck as well as PI3K/Akt pathway

(2017) Yi Wei Hu et al.   Scientific Reports

Grass Carp Laboratory of Genetics and Physiology 2 Serves As a Negative Regulator in Retinoic Acid-Inducible Gene I- and Melanoma Differentiation-Associated Gene 5-Mediated Antiviral Signaling in Resting State and Early Stage of Grass Carp Reovirus Infection

(2017) Youliang Rao et al.   Frontiers in Immunology

MITA/STING and Its Alternative Splicing Isoform MRP Restrict Hepatitis B Virus Replication

(2017) Shuhui Liu et al.   PLoS One

Identification and characterization of the melanoma differentiation – associated gene 5 in sea perch, Lateolabrax japonicus

(2016) Peng Jia et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Molecular characterization and functional analysis of IRF3 in tilapia (Oreochromis niloticus)

(2016) Yi-Feng Gu et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Molecular characterization and expression analysis of mitochondrial antiviral signaling protein gene in sea perch, Lateolabrax japonicus

(2016) Peng Jia et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The evolution and functional characterization of miiuy croaker cytosolic gene LGP2 involved in immune response

(2016) Jingjing Han et al.   FISH & SHELLFISH IMMUNOLOGY

Antiviral function of grouper MDA5 against iridovirus and nodavirus

(2016) Youhua Huang et al.   FISH & SHELLFISH IMMUNOLOGY

Negative regulation of the antiviral response by grouper LGP2 against fish viruses

(2016) Yepin Yu et al.   FISH & SHELLFISH IMMUNOLOGY

LGP2 of black carp plays an important role in the innate immune response against SVCV and GCRV

(2016) Jun Xiao et al.   FISH & SHELLFISH IMMUNOLOGY

Identification and functional characterization of miiuy croaker IRF3 as an inducible protein involved regulation of IFN response

(2016) Chang Shu et al.   FISH & SHELLFISH IMMUNOLOGY

TBK1-like transcript negatively regulates the production of IFN and IFN-stimulated genes through RLRs-MAVS-TBK1 pathway

(2016) Lin Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Molecular characterization and expression analyses of three RIG-I-like receptor signaling pathway genes (MDA5, LGP2 and MAVS) in Larimichthys crocea

(2016) Bin Shen et al.   FISH & SHELLFISH IMMUNOLOGY

Identification of Nod like receptor C3 (NLRC3) in Asian seabass, Lates calcarifer: Characterisation, ontogeny and expression analysis after experimental infection and ligand stimulation

(2016) Anutosh Paria et al.   FISH & SHELLFISH IMMUNOLOGY

Identification and characterization of a novel NOD-like receptor family CARD domain containing 3 gene in response to extracellular ATP stimulation and its role in regulating LPS-induced innate immune response in Japanese flounder (Paralichthys olivaceus) head kidney macrophages

(2016) Shuo Li et al.   FISH & SHELLFISH IMMUNOLOGY

Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure

(2016) Sheryl Coutermarsh-Ott et al.   JOURNAL OF GENERAL VIROLOGY

The P Protein of Spring Viremia of Carp Virus Negatively Regulates the Fish Interferon Response by Inhibiting the Kinase Activity of TANK-Binding Kinase 1

(2016) Shun Li et al.   JOURNAL OF VIROLOGY

NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer

(2016) Rajendra Karki et al.   NATURE

The neurogenetics of alternative splicing

(2016) Celine K. Vuong et al.   NATURE REVIEWS NEUROSCIENCE

Involvement of zebrafish RIG-I in NF-κB and IFN signaling pathways: Insights into functional conservation of RIG-I in antiviral innate immunity

(2015) Li Nie et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

MAVS splicing variants contribute to the induction of interferon and interferon-stimulated genes mediated by RIG-I-like receptors

(2015) Wen Qin Chen et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Antiviral role of grouper STING against iridovirus infection

(2015) Youhua Huang et al.   FISH & SHELLFISH IMMUNOLOGY

Expression profiles and interaction suggest TBK1 can be regulated by Nrdp1 in response to immune stimulation in large yellow croaker Larimichthys crocea

(2015) Dong Ling Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Fish IRF3 up-regulates the transcriptional level of IRF1, IRF2, IRF3 and IRF7 in CIK cells

(2015) Xiaowen Xu et al.   FISH & SHELLFISH IMMUNOLOGY

Higher antiviral response of RIG-I through enhancing RIG-I/MAVS-mediated signaling by its long insertion variant in zebrafish

(2015) Peng Fei Zou et al.   FISH & SHELLFISH IMMUNOLOGY

Molecular characterization and expression analysis of eleven interferon regulatory factors in half-smooth tongue sole, Cynoglossus semilaevis

(2015) Jian Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Identification and characterization of MAVS from black carp Mylopharyngodon piceus

(2015) Wei Zhou et al.   FISH & SHELLFISH IMMUNOLOGY

Characterization of NLR-A subfamily members in miiuy croaker and comparative genomics revealed NLRX1 underwent duplication and lose in actinopterygii

(2015) Jinrui Li et al.   FISH & SHELLFISH IMMUNOLOGY

Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7

(2015) Long-Feng Lu et al.   FISH & SHELLFISH IMMUNOLOGY

Characterization and expression analysis of laboratory of genetics and physiology 2 gene in sea perch, Lateolabrax japonicus

(2015) Peng Jia et al.   FISH & SHELLFISH IMMUNOLOGY

Molecular cloning, characterisation and expression analysis of melanoma differentiation associated gene 5 (MDA5) of green chromide, Etroplus suratensis

(2015) Aadil Bhat et al.   GENE

DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity

(2015) Anetta Härtlova et al.   IMMUNITY

Abortive Infection of Snakehead Fish Vesiculovirus in ZF4 Cells Was Associated with the RLRs Pathway Activation by Viral Replicative Intermediates

(2015) Wenwen Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Steroid responsive regulation of IFNγ2 alternative splicing and its possible role in germ cell proliferation in medaka

(2015) Sipra Mohapatra et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module

(2015) Kristina Ludigs et al.   PLoS Genetics

A Bicistronic MAVS Transcript Highlights a Class of Truncated Variants in Antiviral Immunity

(2014) Sky W. Brubaker et al.   CELL

Regulation of alternative splicing of CD44 in cancer

(2014) Lubomir Prochazka et al.   CELLULAR SIGNALLING

Expression and functional characterization of PGRP6 splice variants in grass carp Ctenopharyngodon idella

(2014) Zhang Long Yu et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Molecular characterizations of grass carp (Ctenopharyngodon idella) TBK1 gene and its roles in regulating IFN-I pathway

(2014) Xiaoli Feng et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection

(2014) Priya Ranjan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NOD-like receptors interfacing the immune and reproductive systems

(2014) Hanne Van Gorp et al.   FEBS Journal

Cloning and expression analyses of interferon regulatory factor (IRF) 3 and 7 genes in European eel, Anguilla anguilla with the identification of genes involved in IFN production

(2014) Bei Huang et al.   FISH & SHELLFISH IMMUNOLOGY

NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING

(2014) Lu Zhang et al.   IMMUNITY

NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease

(2014) Roberta Caruso et al.   IMMUNITY

NLR proteins and parasitic disease

(2014) Gwendolyn M. Clay et al.   IMMUNOLOGIC RESEARCH

NOD-Like Receptors in Intestinal Homeostasis and Epithelial Tissue Repair

(2014) Marianna Parlato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An Alternative Splicing Isoform of MITA Antagonizes MITA-Mediated Induction of Type I IFNs

(2014) H. Chen et al.   JOURNAL OF IMMUNOLOGY

Rhinovirus-Induced Calcium Flux Triggers NLRP3 and NLRC5 Activation in Bronchial Cells

(2013) Kathy Triantafilou et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Selective modulation of MHC class II chaperons by a novel IFN-γ-inducible class II transactivator variant in lung adenocarcinoma A549 cells

(2013) Bau-Lin Chiu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular cloning and functional characterization of peptidoglycan recognition protein 6 in grass carp Ctenopharyngodon idella

(2013) Jun Hua Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Peptidoglycan recognition proteins in Drosophila immunity

(2013) Shoichiro Kurata   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Negative regulation of TBK1-mediated antiviral immunity

(2013) Wei Zhao   FEBS LETTERS

Mechanisms of NOD-like Receptor-Associated Inflammasome Activation

(2013) Haitao Wen et al.   IMMUNITY

The expanding role of NLRs in antiviral immunity

(2013) Christopher Lupfer et al.   IMMUNOLOGICAL REVIEWS

Control of alternative splicing in immune responses: many regulators, many predictions, much still to learn

(2013) Nicole M. Martinez et al.   IMMUNOLOGICAL REVIEWS

Melanoma differentiation-associated gene 5 in zebrafish provoking higher interferon-promoter activity through signalling enhancing of its shorter splicing variant

(2013) Peng Fei Zou et al.   IMMUNOLOGY

An Anti-inflammatory NOD-like Receptor Is Required for Microglia Development

(2013) Celia E. Shiau et al.   Cell Reports

Intracellular Interferons in Fish: A Unique Means to Combat Viral Infection

(2013) Ming-Xian Chang et al.   PLoS Pathogens

The Interplay between NLRs and Autophagy in Immunity and Inflammation

(2013) Leticia A. M. Carneiro et al.   Frontiers in Immunology

Pathogen recognition receptors in channel catfish: II. Identification, phylogeny and expression of retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs)

(2012) K.V. Rajendran et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Cloning and expression analysis of interferon regulatory factor (IRF) 3 and 7 in large yellow croaker, Larimichthys crocea

(2012) Cui-Luan Yao et al.   FISH & SHELLFISH IMMUNOLOGY

Expression profiles of NODs in channel catfish (Ictalurus punctatus) after infection with Edwardsiella tarda, Aeromonas hydrophila, Streptococcus iniae and channel catfish hemorrhage reovirus

(2012) Min Li et al.   FISH & SHELLFISH IMMUNOLOGY

Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity

(2012) Sayuri Nitta et al.   HEPATOLOGY

Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding

(2012) Songying Ouyang et al.   IMMUNITY

Tissue- and Ligand-Specific Sensing of Gram-Negative Infection in Drosophila by PGRP-LC Isoforms and PGRP-LE

(2012) C. Neyen et al.   JOURNAL OF IMMUNOLOGY

NLRs, inflammasomes, and viral infection

(2012) S. R. Jacobs et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Pivotal Role of TBK1 in Inflammatory Responses Mediated by Macrophages

(2012) Tao Yu et al.   MEDIATORS OF INFLAMMATION

Class II, major histocompatibility complex, transactivator (CIITA) in channel catfish: identification and expression patterns responding to different pathogens

(2012) Yang Liu et al.   MOLECULAR BIOLOGY REPORTS

Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING

(2012) Qian Yin et al.   MOLECULAR CELL

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

(2012) Monika Schneider et al.   NATURE IMMUNOLOGY

Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system

(2012) Chang Shu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP

(2012) Guijun Shang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Both STING and MAVS Fish Orthologs Contribute to the Induction of Interferon Mediated by RIG-I

(2012) Stéphane Biacchesi et al.   PLoS One

Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity

(2012) Chia-Yi Yu et al.   PLoS Pathogens

DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

(2012) Sebastian Aguirre et al.   PLoS Pathogens

Identification of novel alternative splicing variants of interferon regulatory factor 3

(2011) Yong Li et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers

(2011) Eleonor Olsson et al.   BMC CANCER

Interferon regulatory factor 3-CL, an isoform of IRF3, antagonizes activity of IRF3

(2011) Chunhua Li et al.   Cellular & Molecular Immunology

Inflammasome activation via intracellular NLRs triggered by bacterial infection

(2011) Yukiko Koizumi et al.   CELLULAR MICROBIOLOGY

Activation of RIG-I-like receptor signal transduction

(2011) Annie M. Bruns et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Alternative splicing takes shape during neuronal development

(2011) Paula Grabowski   CURRENT OPINION IN GENETICS & DEVELOPMENT

Characterization of a TnMAVS protein from Tetraodon nigroviridis

(2011) Zhiming Xiang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Teleost fish interferons and their role in immunity

(2011) Jun Zou et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Transcriptional regulation of type I interferon gene expression by interferon regulatory factor-3 in Japanese flounder, Paralichthys olivaceus

(2011) Maki Ohtani et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Pathogen recognition receptors in channel catfish: I. Identification, phylogeny and expression of NOD-like receptors

(2011) K.V. Rajendran et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish

(2011) S. H. Oehlers et al.   Disease Models & Mechanisms

Identification of a retinoic acid-inducible gene I from grass carp (Ctenopharyngodon idella) and expression analysis in vivo and in vitro

(2011) Chunrong Yang et al.   FISH & SHELLFISH IMMUNOLOGY

Expression profiles of carp IRF-3/-7 correlate with the up-regulation of RIG-I/MAVS/TRAF3/TBK1, four pivotal molecules in RIG-I signaling pathway

(2011) Hong Feng et al.   FISH & SHELLFISH IMMUNOLOGY

Antiviral protection mechanisms mediated by ginbuna crucian carp interferon gamma isoforms 1 and 2 through two distinct interferon gamma-receptors

(2011) Takeshi Yabu et al.   JOURNAL OF BIOCHEMISTRY

Fish MITA Serves as a Mediator for Distinct Fish IFN Gene Activation Dependent on IRF3 or IRF7

(2011) F. Sun et al.   JOURNAL OF IMMUNOLOGY

Expression and Functional Characterization of the RIG-I-Like Receptors MDA5 and LGP2 in Rainbow Trout (Oncorhynchus mykiss)

(2011) M. Chang et al.   JOURNAL OF VIROLOGY

NLRC5: a newly discovered MHC class I transactivator (CITA)

(2011) Torsten B. Meissner et al.   MICROBES AND INFECTION

STING is a direct innate immune sensor of cyclic di-GMP

(2011) Dara L. Burdette et al.   NATURE

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

(2011) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

TBK1 Mediates Crosstalk Between the Innate Immune Response and Autophagy

(2011) H. Weidberg et al.   Science Signaling

RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity

(2011) Hilario J Ramos et al.   Current Opinion in Virology

NLRC5 Negatively Regulates the NF-κB and Type I Interferon Signaling Pathways

(2010) Jun Cui et al.   CELL

Activation of host pattern recognition receptors by viruses

(2010) Kiva Brennan et al.   CURRENT OPINION IN MICROBIOLOGY

IL-28A, IL-28B, and IL-29: Promising cytokines with type I interferon-like properties

(2010) Katrin Witte et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Molecular cloning and antiviral activity of IFN-β promoter stimulator-1 (IPS-1) gene in Japanese flounder, Paralichthys olivaceus

(2010) Rhoda Mae C. Simora et al.   FISH & SHELLFISH IMMUNOLOGY

Molecular cloning and immune responsive expression of MDA5 gene, a pivotal member of the RLR gene family from grass carp Ctenopharyngodon idella

(2010) Jianguo Su et al.   FISH & SHELLFISH IMMUNOLOGY

Identification and expression profiling analysis of grass carp Ctenopharyngodon idella LGP2 cDNA

(2010) Teng Huang et al.   FISH & SHELLFISH IMMUNOLOGY

Molecular cloning, characterization and expression analysis of interferon-β promoter stimulator 1 (IPS-1) gene from grass carp Ctenopharyngodon idella

(2010) Jianguo Su et al.   FISH & SHELLFISH IMMUNOLOGY

Cloning of two rainbow trout nucleotide-binding oligomerization domain containing 2 (NOD2) splice variants and functional characterization of the NOD2 effector domains

(2010) Mingxian Chang et al.   FISH & SHELLFISH IMMUNOLOGY

Interleukin and Interleukin Receptor Diversity: Role of Alternative Splicing

(2010) Anupama Sahoo et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

A Role for the Human Nucleotide-binding Domain, Leucine-rich Repeat-containing Family Member NLRC5 in Antiviral Responses

(2010) Andreas Neerincx et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolutional Conservation of Molecular Structure and Antiviral Function of a Viral RNA Receptor, LGP2, in Japanese Flounder, Paralichthys olivaceus

(2010) M. Ohtani et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: NLRC5-Dependent Activation of the Inflammasome

(2010) B. K. Davis et al.   JOURNAL OF IMMUNOLOGY

The Nucleotide-Binding Oligomerization Domain-Like Receptor NLRC5 Is Involved in IFN-Dependent Antiviral Immune Responses

(2010) Sven Kuenzel et al.   JOURNAL OF IMMUNOLOGY

NLRC5 Deficiency Does Not Influence Cytokine Induction by Virus and Bacteria Infections

(2010) H. Kumar et al.   JOURNAL OF IMMUNOLOGY

Role of Differential Expression of Interferon Receptor Isoforms on the Response of Multiple Sclerosis Patients to Therapy with Interferon Beta

(2010) Francesca Gilli   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The characterization of two novel IRF-3 transcripts starting from intron 2 of the wild type of IRF-3

(2010) Wei Ren et al.   MOLECULAR BIOLOGY REPORTS

Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

(2010) T. Satoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NOD-like subfamily of the nucleotide-binding domain and leucine-rich repeat containing family receptors and their expression in channel catfish

(2009) Zhenxia Sha et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Interleukin-7 (IL-7) and IL-7 splice variants affect differentiation of human neural progenitor cells

(2009) M Moors et al.   GENES AND IMMUNITY

TANK-binding kinase 1 mediates phosphorylation of insulin receptor at serine residue 994: a potential link between inflammation and insulin resistance

(2009) Marina C Muñoz et al.   JOURNAL OF ENDOCRINOLOGY

TANK-Binding Kinase-1 Plays an Important Role during In Vitro and In Vivo Type I IFN Responses to DNA Virus Infections

(2009) A. K. Miyahira et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Antiviral Signaling Protein Plays a Major Role in Induction of the Fish Innate Immune Response against RNA and DNA Viruses

(2009) S. Biacchesi et al.   JOURNAL OF VIROLOGY

Molecular characterization of novel interferon gamma receptor 1 isoforms in zebrafish (Danio rerio) and goldfish (Carassius auratus L.)

(2009) Leon Grayfer et al.   MOLECULAR IMMUNOLOGY

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

(2009) W. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of an Atlantic salmon IFN multigene cluster encoding three IFN subtypes with very different expression properties

(2008) Baojian Sun et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Zebrafish peptidoglycan recognition protein SC (zfPGRP-SC) mediates multiple intracellular signaling pathways

(2008) M.X. Chang et al.   FISH & SHELLFISH IMMUNOLOGY

Characterization of the interferon genes in homozygous rainbow trout reveals two novel genes, alternate splicing and differential regulation of duplicated genes

(2008) Maureen K. Purcell et al.   FISH & SHELLFISH IMMUNOLOGY

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

Pattern recognition receptors and control of adaptive immunity

(2008) Noah W. Palm et al.   IMMUNOLOGICAL REVIEWS

Interferons: Signaling, antiviral and viral evasion

(2008) Cláudio A. Bonjardim et al.   IMMUNOLOGY LETTERS

Negative Regulation of Virus-triggered IFN-β Signaling Pathway by Alternative Splicing of TBK1

(2008) Weiwen Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling☆

(2008) Sonya P. Lad et al.   MOLECULAR IMMUNOLOGY

Inhibition of the IFN-β Response in Hepatocellular Carcinoma by Alternative Spliced Isoform of IFN Regulatory Factor-3

(2008) Sabrina Marozin et al.   MOLECULAR THERAPY

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

Evolution of MDA-5/RIG-I-dependent innate immunity: Independent evolution by domain grafting

(2008) D. Sarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

(2008) M. U. Gack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNAi suppression of zebrafish peptidoglycan recognition protein 6 (zfPGRP6) mediated differentially expressed genes involved in Toll-like receptor signaling pathway and caused increased susceptibility to Flavobacterium columnare

(2008) M.X. Chang et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY