Molecular cloning of MDA5, phylogenetic analysis of RIG-I-like receptors (RLRs) and differential gene expression of RLRs, interferons and proinflammatory cytokines after in vitro challenge with IPNV, ISAV and SAV in the salmonid cell line TO

Molecular characterization and expression analyses of three RIG-I-like receptor signaling pathway genes (MDA5, LGP2 and MAVS) in Larimichthys crocea

(2016) Bin Shen et al.   FISH & SHELLFISH IMMUNOLOGY

NOD2 in zebrafish functions in antibacterial and also antiviral responses via NF-κB, and also MDA5, RIG-I and MAVS

(2016) Peng Fei Zou et al.   FISH & SHELLFISH IMMUNOLOGY

Fish viruses make dsRNA in fish cells: characterization of dsRNA production in rainbow trout (Oncorhynchus mykiss) cells infected with viral haemorrhagic septicaemia virus, chum salmon reovirus and frog virus 3

(2016) L Doherty et al.   JOURNAL OF FISH DISEASES

RIG-I-Like Receptors: One STrEP Forward

(2016) Charlotte Lässig et al.   TRENDS IN MICROBIOLOGY

Comparative analysis of viral RNA signatures on different RIG-I-like receptors

(2016) Raul Y Sanchez David et al.   eLife

De novo assembly and transcriptome analysis of Atlantic salmon macrophage/dendritic-like TO cells following type I IFN treatment and Salmonid alphavirus subtype-3 infection

(2015) Cheng Xu et al.   BMC GENOMICS

Viral RNA detection by RIG-I-like receptors

(2015) Mitsutoshi Yoneyama et al.   CURRENT OPINION IN IMMUNOLOGY

Characterization of interleukin-1β as a proinflammatory cytokine in grass carp (Ctenopharyngodon idella)

(2015) Yun-Xuan Bo et al.   FISH & SHELLFISH IMMUNOLOGY

The expanding repertoire of the IL-12 cytokine family in teleost fish: Identification of three paralogues each of the p35 and p40 genes in salmonids, and comparative analysis of their expression and modulation in Atlantic salmon Salmo salar

(2014) Tiehui Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Effects of TLR agonists and viral infection on cytokine and TLR expression in Atlantic salmon (Salmo salar)

(2014) Marianne Arnemo et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Toll-like receptor recognition of bacteria in fish: Ligand specificity and signal pathways

(2014) Jie Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Teleost TLR22 Recognizes RNA Duplex to Induce IFN and Protect Cells from Birnaviruses

(2014) A. Matsuo et al.   JOURNAL OF IMMUNOLOGY

CDD: NCBI's conserved domain database

(2014) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Innate immune responses of salmonid fish to viral infections

(2013) Bertrand Collet   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Flow cytometry detection of infectious pancreatic necrosis virus (IPNV) within subpopulations of Atlantic salmon (Salmo salar L.) leucocytes after vaccination and during the time course of experimental infection

(2013) Anita Rønneseth et al.   FISH & SHELLFISH IMMUNOLOGY

Innate immunity of finfish: Primordial conservation and function of viral RNA sensors in teleosts

(2013) Takashi Aoki et al.   FISH & SHELLFISH IMMUNOLOGY

The Antiviral Innate Immune Response in Fish: Evolution and Conservation of the IFN System

(2013) Christelle Langevin et al.   JOURNAL OF MOLECULAR BIOLOGY

Signalling C-Type Lectins in Antimicrobial Immunity

(2013) Rebecca A. Drummond et al.   PLoS Pathogens

Countermeasures against viral diseases of farmed fish

(2012) Frederick S.B. Kibenge et al.   ANTIVIRAL RESEARCH

Why does the immune system of Atlantic cod lack MHC II?

(2012) Bastiaan Star et al.   BIOESSAYS

Unipro UGENE: a unified bioinformatics toolkit

(2012) Konstantin Okonechnikov et al.   BIOINFORMATICS

Pathogen recognition receptors in channel catfish: II. Identification, phylogeny and expression of retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs)

(2012) K.V. Rajendran et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

CD40L – A costimulatory molecule involved in the maturation of antigen presenting cells in Atlantic salmon (Salmo salar)

(2012) Leidy X. Lagos et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Atlantic Salmon Type I IFN Subtypes Show Differences in Antiviral Activity and Cell-Dependent Expression: Evidence for High IFNb/IFNc-Producing Cells in Fish Lymphoid Tissues

(2012) T. Svingerud et al.   JOURNAL OF IMMUNOLOGY

Sensing of RNA Viruses: a Review of Innate Immune Receptors Involved in Recognizing RNA Virus Invasion

(2012) S. Jensen et al.   JOURNAL OF VIROLOGY

Functional Characterizations of RIG-I to GCRV and Viral/Bacterial PAMPs in Grass Carp Ctenopharyngodon idella

(2012) Lijun Chen et al.   PLoS One

Antiviral Sensing in Teleost Fish

(2011) Jun Zou et al.   CURRENT PHARMACEUTICAL DESIGN

Teleost fish interferons and their role in immunity

(2011) Jun Zou et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Toll-like receptors in bony fish: From genomics to function

(2011) Yniv Palti   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Early antiviral response and virus-induced genes in fish

(2011) Eloi R. Verrier et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Identification of a retinoic acid-inducible gene I from grass carp (Ctenopharyngodon idella) and expression analysis in vivo and in vitro

(2011) Chunrong Yang et al.   FISH & SHELLFISH IMMUNOLOGY

Expression and Functional Characterization of the RIG-I-Like Receptors MDA5 and LGP2 in Rainbow Trout (Oncorhynchus mykiss)

(2011) M. Chang et al.   JOURNAL OF VIROLOGY

Evolutional Conservation of Molecular Structure and Antiviral Function of a Viral RNA Receptor, LGP2, in Japanese Flounder, Paralichthys olivaceus

(2010) M. Ohtani et al.   JOURNAL OF IMMUNOLOGY

The fight between the teleost fish immune response and aquatic viruses

(2010) Samuel T. Workenhe et al.   MOLECULAR IMMUNOLOGY

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

(2010) Yanli Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Origin and evolution of the RIG-I like RNA helicase gene family

(2009) Jun Zou et al.   BMC EVOLUTIONARY BIOLOGY

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Reference genes evaluated for use in infectious pancreatic necrosis virus real-time RT-qPCR assay applied during different stages of an infection

(2009) K. Julin et al.   JOURNAL OF VIROLOGICAL METHODS

Mitochondrial Antiviral Signaling Protein Plays a Major Role in Induction of the Fish Innate Immune Response against RNA and DNA Viruses

(2009) S. Biacchesi et al.   JOURNAL OF VIROLOGY

Activation of innate immune antiviral responses by Nod2

(2009) Ahmed Sabbah et al.   NATURE IMMUNOLOGY

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

(2009) A. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of an Atlantic salmon IFN multigene cluster encoding three IFN subtypes with very different expression properties

(2008) Baojian Sun et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

A highly phagocytic cell line TO from Atlantic salmon is CD83 positive and M-CSFR negative, indicating a dendritic-like cell type

(2008) Eirin Fausa Pettersen et al.   FISH & SHELLFISH IMMUNOLOGY

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE