NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection

Unusual Structural Features Revealed by the Solution NMR Structure of the NLRC5 Caspase Recruitment Domain

(2014) Petrus G. M. Gutte et al.   BIOCHEMISTRY

An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages

(2014) Faruk Sheikh et al.   JOURNAL OF LEUKOCYTE BIOLOGY

RIG-I Goes Beyond Naked Recognition

(2013) J. Bradford Bowzard et al.   Cell Host & Microbe

Incoming RNA Virus Nucleocapsids Containing a 5′-Triphosphorylated Genome Activate RIG-I and Antiviral Signaling

(2013) Michaela Weber et al.   Cell Host & Microbe

Expression regulation and function of NLRC5

(2013) Yikun Yao et al.   Protein & Cell

The nucleotide-binding domain of NLRC5 is critical for nuclear import and transactivation activity

(2012) Torsten B. Meissner et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NLRC5 knockdown in chicken macrophages alters response to LPS and poly (I:C) stimulation

(2012) Ling Lian et al.   BMC Veterinary Research

NLRC5: a NOD-like receptor protein with many faces in immune regulation

(2012) Yue Zhao et al.   CELL RESEARCH

NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens

(2012) Yikun Yao et al.   CELL RESEARCH

Enhanced TLR-induced NF-κB signaling and type I interferon responses in NLRC5 deficient mice

(2012) Yanzheng Tong et al.   CELL RESEARCH

Regulation of Class I Major Histocompatibility Complex (MHC) by Nucleotide-binding Domain, Leucine-rich Repeat-containing (NLR) Proteins

(2012) Gregory R. Robbins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NLRC5 Controls Basal MHC Class I Gene Expression in an MHC Enhanceosome-Dependent Manner

(2012) A. Neerincx et al.   JOURNAL OF IMMUNOLOGY

NLRC5 Deficiency Selectively Impairs MHC Class I- Dependent Lymphocyte Killing by Cytotoxic T Cells

(2012) F. Staehli et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Impaired MHC Class I Expression in Mice Deficient for Nlrc5/Class I Transactivator

(2012) A. Biswas et al.   JOURNAL OF IMMUNOLOGY

NLRC5 Cooperates with the RFX Transcription Factor Complex To Induce MHC Class I Gene Expression

(2012) T. B. Meissner et al.   JOURNAL OF IMMUNOLOGY

LPS Regulates SOCS2 Transcription in a Type I Interferon Dependent Autocrine-Paracrine Loop

(2012) Jin Hu et al.   PLoS One

NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

(2011) Irving C. Allen et al.   IMMUNITY

Regulation of immune pathways by the NOD-like receptor NLRC5

(2011) Mohamed Lamkanfi et al.   IMMUNOBIOLOGY

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Influenza C virus NS1 protein counteracts RIG-I-mediated IFN signalling

(2011) Karin Pachler et al.   Virology Journal

RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications

(2011) Reneé C. Ireton et al.   Viruses-Basel

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

NLRC5 Negatively Regulates the NF-κB and Type I Interferon Signaling Pathways

(2010) Jun Cui et al.   CELL

Activation of cytokine-producing and antitumor activities of natural killer cells and macrophages by engagement of Toll-like and NOD-like receptors

(2010) Fu Qiu et al.   Innate Immunity

A Role for the Human Nucleotide-binding Domain, Leucine-rich Repeat-containing Family Member NLRC5 in Antiviral Responses

(2010) Andreas Neerincx et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatocytes express functional NOD1 and NOD2 receptors: A role for NOD1 in hepatocyte CC and CXC chemokine production

(2010) Melanie J. Scott et al.   JOURNAL OF HEPATOLOGY

NLRC5 Limits the Activation of Inflammatory Pathways

(2010) S. Benko et al.   JOURNAL OF IMMUNOLOGY

The Nucleotide-Binding Oligomerization Domain-Like Receptor NLRC5 Is Involved in IFN-Dependent Antiviral Immune Responses

(2010) Sven Kuenzel et al.   JOURNAL OF IMMUNOLOGY

NLRC5 Deficiency Does Not Influence Cytokine Induction by Virus and Bacteria Infections

(2010) H. Kumar et al.   JOURNAL OF IMMUNOLOGY

Respiratory Syncytial Virus-Mediated NF- B p65 Phosphorylation at Serine 536 Is Dependent on RIG-I, TRAF6, and IKK 

(2010) F. Yoboua et al.   JOURNAL OF VIROLOGY

Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication

(2010) K. V. Chakravarthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes

(2010) T. B. Meissner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of RIG-I with innate immunity of ducks to influenza

(2010) M. R. W. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication

(2010) Priya Ranjan et al.   Virology Journal

Cytoplasmic nucleic acid sensors in antiviral immunity

(2009) Priya Ranjan et al.   TRENDS IN MOLECULAR MEDICINE

RIG-I activation inhibits ebolavirus replication

(2009) Christina F. Spiropoulou et al.   VIROLOGY

Sabotage of antiviral signaling and effectors by influenza viruses

(2008) Thorsten Wolff et al.   BIOLOGICAL CHEMISTRY

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses

(2008) Kiyohiro Takahasi et al.   MOLECULAR CELL

Amantadine-resistance among H5N1 avian influenza viruses isolated in Northern China

(2007) Guimei He et al.   ANTIVIRAL RESEARCH