Mucosal immune tolerance at the ocular surface in health and disease

Desiccating stress-induced disruption of ocular surface immune tolerance drives dry eye disease

(2016) M. Guzmán et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Mucosal tolerance disruption favors disease progression in an extraorbital lacrimal gland excision model of murine dry eye

(2016) Mauricio Guzmán et al.   EXPERIMENTAL EYE RESEARCH

Identification, Isolation, and Functional Assay of Regulatory T Cells

(2016) Maryam Azimi et al.   IMMUNOLOGICAL INVESTIGATIONS

Immunity and Tolerance Induced by Intestinal Mucosal Dendritic Cells

(2016) Julio Aliberti   MEDIATORS OF INFLAMMATION

Impact of Microbiome on Ocular Health

(2016) Abirami Kugadas et al.   Ocular Surface

Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation

(2016) Asiel Arce-Sillas et al.   Journal of Immunology Research

Altered Mucosal Microbiome Diversity and Disease Severity in Sjögren Syndrome

(2016) Cintia S. de Paiva et al.   Scientific Reports

Impact of wildfire smoke in Buenos Aires, Argentina, on ocular surface

(2015) Martin Berra et al.   ARQUIVOS BRASILEIROS DE OFTALMOLOGIA

Prevention of allergic conjunctivitis in mice by a rice-based edible vaccine containing modified Japanese cedar pollen allergens

(2015) Ken Fukuda et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Airway responses towards allergens - from the airway epithelium to T cells

(2015) D. Papazian et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Homeostatic NF-κB Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance

(2015) Myriam Baratin et al.   IMMUNITY

Oral Delivery of Particulate Transforming Growth Factor Beta 1 and All-Trans Retinoic Acid Reduces Gut Inflammation in Murine Models of Inflammatory Bowel Disease

(2015) Thomas F. Conway et al.   Journal of Crohns & Colitis

Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16

(2015) B B Menon et al.   Mucosal Immunology

Three cheers for the goblet cell: maintaining homeostasis in mucosal epithelia

(2015) Heather A. McCauley et al.   TRENDS IN MOLECULAR MEDICINE

Immunomodulatory Cross-Talk between Conjunctival Goblet Cells and Dendritic Cells

(2015) Laura Contreras-Ruiz et al.   PLoS One

Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye

(2015) Aditi Bauskar et al.   PLoS One

Considerations in Understanding the Ocular Surface Microbiome

(2014) Michael E. Zegans et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Oral azithromycin versus doxycycline in meibomian gland dysfunction: a randomised double-masked open-label clinical trial

(2014) Mohsen Bahmani Kashkouli et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Trends in prevalence and treatment of ocular allergy

(2014) Paulo J. Gomes   Current Opinion in Allergy and Clinical Immunology

T helper subsets in allergic eye disease

(2014) Nancy J. Reyes et al.   Current Opinion in Allergy and Clinical Immunology

A potential link between bacterial pathogens and allergic conjunctivitis by dendritic cells

(2014) Ruzhi Deng et al.   EXPERIMENTAL EYE RESEARCH

Regulatory T cells and their roles in immune dysregulation and allergy

(2014) Laurence Pellerin et al.   IMMUNOLOGIC RESEARCH

Dendritic cell-epithelial cell crosstalk in the gut

(2014) Maria Rescigno   IMMUNOLOGICAL REVIEWS

Autoimmunity in Dry Eye Is Due to Resistance of Th17 to Treg Suppression

(2014) S. K. Chauhan et al.   JOURNAL OF IMMUNOLOGY

Desiccating Stress–Induced Chemokine Expression in the Epithelium Is Dependent on Upregulation of NKG2D/RAE-1 and Release of IFN-γ in Experimental Dry Eye

(2014) Terry G. Coursey et al.   JOURNAL OF IMMUNOLOGY

Subsets of regulatory T cells and their roles in allergy

(2014) Huiyun Zhang et al.   Journal of Translational Medicine

Outdoor air pollution and asthma

(2014) Michael Guarnieri et al.   LANCET

Regulation of Toll-Like Receptor Expression in Human Conjunctival Epithelial Cells

(2014) Jing Li et al.   MEDIATORS OF INFLAMMATION

Bystander immunotherapy as a strategy to control allergen-driven airway inflammation

(2014) S Navarro et al.   Mucosal Immunology

The gut microbiota and inflammatory bowel disease

(2014) Katsuyoshi Matsuoka et al.   Seminars in Immunopathology

The ocular surface epithelial barrier and other mechanisms of mucosal protection

(2013) Flavio Mantelli et al.   Current Opinion in Allergy and Clinical Immunology

Characterization of the normal microbiota of the ocular surface

(2013) Mark D.P. Willcox   EXPERIMENTAL EYE RESEARCH

Antimicrobial compounds in tears

(2013) Alison M. McDermott   EXPERIMENTAL EYE RESEARCH

Emerging therapies in allergic conjunctivitis and dry eye syndrome

(2013) Michael Nye et al.   EXPERT OPINION ON PHARMACOTHERAPY

Intestinal epithelial cells as mediators of the commensal-host immune crosstalk

(2013) Yoshiyuki Goto et al.   IMMUNOLOGY AND CELL BIOLOGY

Dry Eye as a Mucosal Autoimmune Disease

(2013) Michael E. Stern et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Soluble antigen traffics rapidly and selectively from the corneal surface to the eye draining lymph node and activates T cells when codelivered with CpG oligonucleotides

(2013) Zexu Dang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CD8+ cells regulate the T helper-17 response in an experimental murine model of Sjögren syndrome

(2013) X Zhang et al.   Mucosal Immunology

Chronic dry eye disease is principally mediated by effector memory Th17 cells

(2013) Y Chen et al.   Mucosal Immunology

Role of Hyperosmolarity in the Pathogenesis and Management of Dry Eye Disease: Proceedings of the OCEAN Group Meeting

(2013) Christophe Baudouin et al.   Ocular Surface

Ocular Mucosal CD11b+ and CD103+ Mouse Dendritic Cells under Normal Conditions and in Allergic Immune Responses

(2013) Payal Khandelwal et al.   PLoS One

Staphylococcus aureus Activates the NLRP3 Inflammasome in Human and Rat Conjunctival Goblet Cells

(2013) Victoria E. McGilligan et al.   PLoS One

Chemokine Receptors CCR6 and CXCR3 Are Necessary for CD4+ T Cell Mediated Ocular Surface Disease in Experimental Dry Eye Disease

(2013) Terry G. Coursey et al.   PLoS One

Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

(2013) M. Shan et al.   SCIENCE

Effects of diesel exhaust particles on primary cultured healthy human conjunctival epithelium

(2012) Hiroshi Fujishima et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Safety and Efficacy of Antigen-Specific Regulatory T-Cell Therapy for Patients With Refractory Crohn's Disease

(2012) Pierre Desreumaux et al.   GASTROENTEROLOGY

Role of NF-κB in epithelial biology

(2012) Manolis Pasparakis   IMMUNOLOGICAL REVIEWS

Benzalkonium chloride breaks down conjunctival immunological tolerance in a murine model

(2012) J G Galletti et al.   Mucosal Immunology

Oral tolerance to food protein

(2012) O Pabst et al.   Mucosal Immunology

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

(2012) Jeremiah R. McDole et al.   NATURE

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Nuclear Factor-κB: Central Regulator in Ocular Surface Inflammation and Diseases

(2012) Wanwen Lan et al.   Ocular Surface

NK Cells Promote Th-17 Mediated Corneal Barrier Disruption in Dry Eye

(2012) Xiaobo Zhang et al.   PLoS One

Ocular surface inflammation is regulated by innate immunity

(2012) Mayumi Ueta et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Strategies of mucosal immunotherapy for allergic diseases

(2011) Yi-Ling Ye et al.   Cellular & Molecular Immunology

Modulation of the canonical Wnt pathway by Benzalkonium Chloride in corneal epithelium

(2011) Yueping Zhou et al.   EXPERIMENTAL EYE RESEARCH

Toll-like receptor activation modulates antimicrobial peptide expression by ocular surface cells

(2011) Rachel L. Redfern et al.   EXPERIMENTAL EYE RESEARCH

Interferon-γ-secreting NK cells promote induction of dry eye disease

(2011) Yihe Chen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pulmonary CD103+ dendritic cells prime Th2 responses to inhaled allergens

(2011) H Nakano et al.   Mucosal Immunology

Distribution of Primed T Cells and Antigen-Loaded Antigen Presenting Cells Following Intranasal Immunization in Mice

(2011) Annalisa Ciabattini et al.   PLoS One

Disruption of TGF-β Signaling Improves Ocular Surface Epithelial Disease in Experimental Autoimmune Keratoconjunctivitis Sicca

(2011) Cintia S. De Paiva et al.   PLoS One

Modulation of epithelial immunity by mucosal fluid

(2011) James J. Mun et al.   Scientific Reports

NF-κB in the regulation of epithelial homeostasis and inflammation

(2010) Andy Wullaert et al.   CELL RESEARCH

Nasolacrimal Duct Closure Modulates Ocular Mucosal and Systemic CD4+ T-Cell Responses Induced following Topical Ocular or Intranasal Immunization

(2010) A. A. Chentoufi et al.   Clinical and Vaccine Immunology

Dendritic cell physiology and function in the eye

(2010) John V. Forrester et al.   IMMUNOLOGICAL REVIEWS

Eye Mucosa: An Efficient Vaccine Delivery Route for Inducing Protective Immunity

(2010) K. Y. Seo et al.   JOURNAL OF IMMUNOLOGY

Epithelial decision makers: in search of the 'epimmunome'

(2010) Mahima Swamy et al.   NATURE IMMUNOLOGY

Immune Privilege of Corneal Allografts

(2010) Jerry Y. Niederkorn et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Preservatives in eyedrops: The good, the bad and the ugly

(2010) Christophe Baudouin et al.   PROGRESS IN RETINAL AND EYE RESEARCH

In vivoconfocal microscopy of the bulbar conjunctiva

(2009) Nathan Efron et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Analysis of Inflammatory Cytokines in the Tears of Dry Eye Patients

(2009) Morgan L Massingale et al.   CORNEA

Concomitant Inhalation of Cigarette Smoke and Aerosolized Protein Activates Airway Dendritic Cells and Induces Allergic Airway Inflammation in a TLR-Independent Way

(2009) L. J. Robays et al.   JOURNAL OF IMMUNOLOGY

T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade

(2008) Dmitry V. Ostanin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tear cytokine and ocular surface alterations following brief passive cigarette smoke exposure

(2008) Van Tuan Rummenie et al.   CYTOKINE

Alterations of the tear film and ocular surface health in chronic smokers

(2008) Y Matsumoto et al.   EYE