Journal
OCULAR SURFACE
Volume 14, Issue 3, Pages 342-349Publisher
ELSEVIER
DOI: 10.1016/j.jtos.2016.04.004
Keywords
contact lenses; IgA; microbiota; ocular surface
Categories
Funding
- Public Health Service grant from the National Eye Institute [EY022054]
- American Association of Immunology Fellowship [2015D001576]
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The ocular surface is continuously exposed to the environment and, therefore, it is surprising that it harbors only few commensals with low degree of diversity. This unique aspect of the ocular surface physiology prompts the question whether there are core ocular commensal communities and how they affect ocular immunity. The purpose of this review is to provide an overview of what is known about the ocular surface commensals in health and disease and what we would like to learn in the near future. In addition, we discuss how microbiota at sites other than the eye may influence ocular immune responses. The information discussed in the review has been gathered using PubMed searches for literature published from January 1982 to December 2015.
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