Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires

Ultra-high-throughput sequencing of the immune receptor repertoire from millions of lymphocytes

(2016) Jonathan R McDaniel et al.   Nature Protocols

λ Light Chain Bias Associated With Enhanced Binding and Function of Anti-HIV Env Glycoprotein Antibodies

(2015) Mohammad M. Sajadi et al.   JOURNAL OF INFECTIOUS DISEASES

Restricted, canonical, stereotyped and convergent immunoglobulin responses

(2015) Carole J. Henry Dunand et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales

(2015) Gur Yaari et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

In-Depth Assessment of Within-Individual and Inter-Individual Variation in the B Cell Receptor Repertoire

(2015) Jacob D. Galson et al.   Frontiers in Immunology

Analysis of B Cell Repertoire Dynamics Following Hepatitis B Vaccination in Humans, and Enrichment of Vaccine-specific Antibody Sequences

(2015) Jacob D. Galson et al.   EBioMedicine

Human Responses to Influenza Vaccination Show Seroconversion Signatures and Convergent Antibody Rearrangements

(2014) Katherine J.L. Jackson et al.   Cell Host & Microbe

The promise and challenge of high-throughput sequencing of the antibody repertoire

(2014) George Georgiou et al.   NATURE BIOTECHNOLOGY

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

(2014) Brandon J DeKosky et al.   NATURE MEDICINE

Sequencing the functional antibody repertoire—diagnostic and therapeutic discovery

(2014) William H. Robinson   Nature Reviews Rheumatology

Redistribution of Flexibility in Stabilizing Antibody Fragment Mutants Follows Le Châtelier’s Principle

(2014) Tong Li et al.   PLoS One

Identification and characterization of the constituent human serum antibodies elicited by vaccination

(2014) Jason J. Lavinder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution modeling of antibody structures by a combination of bioinformatics, expert knowledge, and molecular simulations

(2014) Hiroki Shirai et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Antibody modeling assessment II. Structures and models

(2014) Alexey Teplyakov et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Blind prediction performance of RosettaAntibody 3.0: Grafting, relaxation, kinematic loop modeling, and full CDR optimization

(2014) Brian D. Weitzner et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

AutomatedAufbauof antibody structures from given sequences using Macromoltek's SmrtMolAntibody

(2014) Monica Berrondo et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Antibody structure determination using a combination of homology modeling, energy-based refinement, and loop prediction

(2014) Kai Zhu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Differences in the Composition of the Human Antibody Repertoire by B Cell Subsets in the Blood

(2014) Eva Szymanska Mroczek et al.   Frontiers in Immunology

Convergent Antibody Signatures in Human Dengue

(2013) Poornima Parameswaran et al.   Cell Host & Microbe

Intrinsic bias and public rearrangements in the human immunoglobulin Vλ light chain repertoire

(2013) K H Hoi et al.   GENES AND IMMUNITY

Igs Expressed by Chronic Lymphocytic Leukemia B Cells Show Limited Binding-Site Structure Variability

(2013) P. Marcatili et al.   JOURNAL OF IMMUNOLOGY

Antibody and Antigen Contact Residues Define Epitope and Paratope Size and Structure

(2013) J. W. Stave et al.   JOURNAL OF IMMUNOLOGY

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

(2013) Brandon J DeKosky et al.   NATURE BIOTECHNOLOGY

The Shape of the Lymphocyte Receptor Repertoire: Lessons from the B Cell Receptor

(2013) Katherine J. L. Jackson et al.   Frontiers in Immunology

IgM memory B cells: a mouse/human paradox

(2012) Claude-Agnès Reynaud et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

High-throughput antibody sequencing reveals genetic evidence of global regulation of the naïve and memory repertoires that extends across individuals

(2012) B S Briney et al.   GENES AND IMMUNITY

Fully human monoclonal antibodies from antibody secreting cells after vaccination with Pneumovax®23 are serotype specific and facilitate opsonophagocytosis

(2012) Kenneth Smith et al.   IMMUNOBIOLOGY

Global analysis of B cell selection using an immunoglobulin light chain–mediated model of autoreactivity

(2012) Sarah F. Andrews et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antibody Repertoires in Humanized NOD-scid-IL2Rγnull Mice and Human B Cells Reveals Human-Like Diversification and Tolerance Checkpoints in the Mouse

(2012) Gregory C. Ippolito et al.   PLoS One

Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

(2012) A. G. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germline VH/VL pairing in antibodies

(2012) N. Jayaram et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Advances in Human B Cell Phenotypic Profiling

(2012) Denise A. Kaminski et al.   Frontiers in Immunology

Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells

(2011) Katherine Jean Louise Jackson et al.   IMMUNOGENETICS

High-Resolution Description of Antibody Heavy-Chain Repertoires in Humans

(2011) Ramy Arnaout et al.   PLoS One

Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation

(2011) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Relationship between CD27 Negative and Positive B Cell Populations in Human Peripheral Blood

(2011) Yu-Chang Bryan Wu et al.   Frontiers in Immunology

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

(2010) Y.-C. Wu et al.   BLOOD

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

The influence of the framework core residues on the biophysical properties of immunoglobulin heavy chain variable domains

(2009) Annemarie Honegger et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Conserved amino acid networks involved in antibody variable domain interactions

(2008) Norman Wang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS