Control of hepatocyte proliferation and survival by Fgf receptors is essential for liver regeneration in mice

Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations

(2014) Howard R. Mellor   LIVER INTERNATIONAL

Knockdown and knockout of β1-integrin in hepatocytes impairs liver regeneration through inhibition of growth factor signalling

(2014) Tobias Speicher et al.   Nature Communications

FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration

(2013) H. M. Takase et al.   GENES & DEVELOPMENT

Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice

(2013) Iker Uriarte et al.   GUT

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

(2012) Muthusamy Jayaraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice

(2012) Lisheng Zhang et al.   HEPATOLOGY

Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

(2012) Anja Zeigerer et al.   NATURE

Targeting FGFR4 Inhibits Hepatocellular Carcinoma in Preclinical Mouse Models

(2012) Dorothy M. French et al.   PLoS One

Forkhead Box M1 (FoxM1) Gene Is a New STAT3 Transcriptional Factor Target and Is Essential for Proliferation, Survival and DNA Repair of K562 Cell Line

(2012) André L. Mencalha et al.   PLoS One

Regulation of liver regeneration by growth factors and cytokines

(2010) Friederike Böhm et al.   EMBO Molecular Medicine

FGF Receptors 1 and 2 Control Chemically Induced Injury and Compound Detoxification in Regenerating Livers of Mice

(2010) Friederike Böhm et al.   GASTROENTEROLOGY

Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

(2010) Akin Akinc et al.   MOLECULAR THERAPY

Lipid-like materials for low-dose, in vivo gene silencing

(2010) K. T. Love et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of hepatic transporters in prevention of bile acid toxicity after partial hepatectomy in mice

(2009) Iván L. Csanaky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation

(2009) Xinle Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention

(2008) Han Kiat Ho et al.   JOURNAL OF HEPATOLOGY

Significance and Mechanism of CYP7a1 Gene Regulation during the Acute Phase of Liver Regeneration

(2008) Lisheng Zhang et al.   MOLECULAR ENDOCRINOLOGY