Review
Food Science & Technology
Zahra Kazemi-Taskooh, Mehdi Varidi
Summary: Protein carriers enhance iron bioavailability and reduce pro-oxidant role, while carbohydrates lead to slow iron release. Iron-loaded lipid-based vehicles face issues of oxidation and leakage, which are decreased in the presence of composite systems.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Ana Ciric, Dorde Medarevic, Bojan Calija, Vladimir Dobricic, Milena Rmandic, Tanja Barudzija, Andelija Malenovic, Ljiljana Djekic
Summary: The entrapment procedure of a poorly water soluble drug was studied to investigate its effect on the physicochemical and drug release performances of chitosan/xanthan polyelectrolyte complexes (PECs). Different drug entrapment procedures and chitosan-to-xanthan mass ratios were observed to affect the formation of PECs, leading to controlled drug release with zero-order kinetics.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Jinglei Li, Haishan Wu, Kexin Jiang, Yuting Liu, Liu Yang, Hyun Jin Park
Summary: An effective delivery system for oral insulin administration was developed using alginate microbeads containing chitosan nanoparticles (CNP) for controlled release of insulin. The optimized CNP with a size around 150 nm and encapsulation efficiency of 23.70% showed promising potential for oral insulin delivery. The insulin-loaded alginate microbeads significantly lowered blood glucose level in hyperglycemia model mice in a controlled manner for up to 96 hours, demonstrating the potential for extended release of insulin.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Rim Nasri, Marwa Hamdi, Sana Touir, Suming Li, Maha Karra-Chaabouni, Moncef Nasri
Summary: This study aimed to encapsulate goby fish protein hydrolysate with antioxidant activity into microparticles using ionic gelation process. The loaded microparticles showed improved encapsulation efficiency and reduced particle size with increasing GPH concentration. Additionally, the encapsulated biopeptides exhibited enhanced thermal stability and followed a diffusion-controlled mechanism for release kinetics, leading to improved antioxidant activity compared to unloaded microparticles.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Food Science & Technology
Sareh Boostani, Seid Mahdi Jafari
Summary: This study comprehensively reviews the principles and design methods of controlled release systems in the food sector, emphasizing the importance of CR systems in enhancing the performance of bioactive food ingredients. Different release mechanisms and potential carriers are discussed, providing insights into the rational design of controlled delivery formulas.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Review
Pharmacology & Pharmacy
Jiaqi Weng, Alain Durand, Stephane Desobry
Summary: This article reviews the state of the art in using chitosan (CS) for preparing particulate carriers for drug delivery applications. It discusses the relationship between targeted controlled activity, preparation process, and release kinetics, focusing on matrix particles and capsules. The article emphasizes the relationship between the size/structure of CS-based particles and drug release kinetics, and reviews various techniques for characterizing particle properties. Mathematical models play a crucial role in understanding release mechanisms and identifying key structural characteristics, leading to the development of a novel design strategy for drug delivery devices.
Review
Biochemistry & Molecular Biology
Eduardo Silveira Ribeiro, Bruna Silva de Farias, Tito Roberto Sant'Anna Cadaval Junior, Luiz Antonio de Almeida Pinto, Patricia Silva Diaz
Summary: Chitosan-based nanofibers exhibit outstanding properties for enzyme immobilization, enhancing stability and efficiency. Different methods of enzyme immobilization, such as adsorption, cross-linking, and entrapment, each have their own advantages and challenges that need to be addressed. The application of chitosan-based nanofibers in enzyme immobilization offers opportunities to improve catalytic activity and extend the lifetime of enzymes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Ivan M. Savic, Ivana M. Savic Gajic, Miljana G. Milovanovic, Stanko Zerajic, Dragoljub G. Gajic
Summary: This study optimized the ultrasound-assisted extraction of antioxidants from orange peels and improved the release of antioxidants through encapsulation. The encapsulated beads can be applied as natural active ingredients in food, cosmetics, and pharmaceutical products.
Article
Biochemistry & Molecular Biology
Darikha Kudasova, Botagoz Mutaliyeva, Kristina Vlahovicek-Kahlina, Slaven Juric, Marijan Marijan, Svetlana V. Khalus, Alexander V. Prosyanik, Suzana Segota, Nikola Spanic, Marko Vincekovic
Summary: The newly synthesized Cu(II) complex has significant effects on plant growth depending on the culture type and concentration, particularly in promoting the development of corn roots. The use of chitosan-coated microcapsules allows effective delivery of Cu(II) complex to plants, with Fickian diffusion being the main release mechanism.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Weiwei Li, Di Liu, Laicui Song, Hao Li, Shijie Dai, Ya Su, Qianjin Li, Jianlin Li, Tiesong Zheng
Summary: Surface modified pH-responsive porous silicon (PSi) carriers were developed for efficient delivery of lutein. The chitosan-coated oxidized PSi can effectively deliver lutein in a targeted and controlled manner and show good biocompatibility in vivo.
Article
Chemistry, Applied
Hujun Xie, Chengzhi Liu, Jian Gao, Jieyu Shi, Fangfang Ni, Xin Luo, Ying He, Gerui Ren, Zisheng Luo
Summary: Complex nanoparticles of Zein-Lecithin-EGCG were successfully fabricated, showing high encapsulation efficiency and antioxidative capacity. The release of EGCG in simulated gastric and intestinal fluids behaved closely to Fick and First release mechanisms, respectively. The encapsulation of EGCG by Z-L nanocomplexes was achieved through electrostatic, hydrophobic, and hydrogen bonding interactions, leading to excellent stability and sustained release performance for potential applications in the food industry.
Article
Biotechnology & Applied Microbiology
Helton Jose Wiggers, Pascale Chevallier, Francesco Copes, Fernanda Heloisa Simch, Felipe da Silva Veloso, Giovana Maria Genevro, Diego Mantovani
Summary: Natural polymer-based films, specifically chitosan films, have been extensively studied as coatings for biomedical applications due to their favorable biological and mechanical properties. In this study, chitosan films crosslinked with quercetin were used as controlled release systems for the antibiotic drug trimethoprim. The results show that quercetin increases the crosslinking degree of chitosan films in a dose-dependent manner, affecting the release kinetics of the loaded drug while maintaining its antibacterial effects. This work demonstrates the potential of quercetin-crosslinked chitosan films as antibiotic-releasing coatings for biomedical applications.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Zahra Kaboudi, Seyed Hadi Peighambardoust, Himan Nourbakhsh, Maral Soltanzadeh
Summary: In this study, the essential oil from Ferulago angulata was stabilized within chitosan nanoparticles using ionic-gelation technique. The major components of the essential oil were identified as alpha-pinene, beta-ocimene, bornyl acetate, and thymol. The essential oil exhibited strong antibacterial activity against S. aureus and E. coli. The chitosan to essential oil ratio of 1:1.25 showed the highest encapsulation efficiency and loading capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Pharmacology & Pharmacy
Taha Umair Wani, Altaf Hussain Pandith, Faheem A. Sheikh
Summary: The review highlights the importance of chitosan in biomedical applications, discussing its physicochemical properties and their impact on formulation development. The charge density and physicochemical properties of chitosan play a crucial role in determining the effectiveness of its applications.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
M. Rahim, M. R. H. Mas Haris
Summary: A green biocomposite was prepared with chitosan dispersed in partially cross-linked natural rubber matrices. Chitosan was well dispersed in the matrices, indicating successful stabilization of natural rubber latex by sodium dodecyl sulfate. The biocomposites showed good swelling properties and were used for controlled release of urea.
MATERIALS TODAY CHEMISTRY
(2021)
Review
Food Science & Technology
Niamh M. Murray, Jean Christophe Jacquier, Michael O'Sullivan, Aine Hallihan, Eoin Murphy, Emma L. Feeney, Dolores O'Riordan
FOOD QUALITY AND PREFERENCE
(2019)
Article
Chemistry, Applied
Dongdong Yuan, E. Dolores O'Riordan, Jean Christophe Jacquier
Article
Food Science & Technology
Dongdong Yuan, Chengtao Wang, Ya Liu, Sheng Lei, Yanjun Wen
JOURNAL OF FOOD SCIENCE
(2019)
Review
Food Science & Technology
Fernando Luis Barroso da Silva, Paolo Carloni, David Cheung, Grazia Cottone, Serena Donnini, E. Allen Foegeding, Muhammad Gulzar, Jean Christophe Jacquier, Vladimir Lobaskin, Donal MacKernan, Zeynab Mohammad Hosseini Naveh, Ravi Radhakrishnan, Erik E. Santiso
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11
(2020)
Review
Food Science & Technology
Konstantinos Papoutsis, Simona Grasso, Ajay Menon, Nigel P. Brunton, James G. Lyng, Jean-Christophe Jacquier, Deep Jyoti Bhuyan
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2020)
Article
Chemistry, Applied
Dongdong Yuan, Sheng Lei, Li Gao, Ya Liu, Guorong Liu, Chengtao Wang
Article
Food Science & Technology
Yang Li, Yan Li, Dongdong Yuan, Yunna Wang, Meiling Li, Liebing Zhang
INTERNATIONAL DAIRY JOURNAL
(2020)
Article
Food Science & Technology
Yanhui Zhang, Hao Yang, Hongxia Zheng, Dongdong Yuan, Like Mao
Summary: Emulsion gels with potato starch in the continuous phase and octenyl succinic anhydride (OSA) starch at the interface were developed to modulate salt release. Increasing emulsion volume led to gels with higher storage modulus and stiffness, affecting the speed and amount of salt release.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Review
Nutrition & Dietetics
Liang Zhao, Arshad Mehmood, Dongdong Yuan, Muhammad Usman, Mian Anjum Murtaza, Sanabil Yaqoob, Chengtao Wang
Summary: Alcoholic liver disease is a serious liver condition caused by alcohol consumption, which can progress to severe liver damage. Current therapeutic interventions are limited, but studies suggest that edible food plants and their bioactive compounds may offer protective effects against ALD.
Article
Nanoscience & Nanotechnology
Rong Nie, Xu Hao, Guorong Liu, Zhao Wang, Zekang Zhu, Dongdong Yuan, Duoxia Xu
Summary: This study focused on the preparation and characterization of anti-microbial biodegradable films based on PVA-CS incorporated with Bifidocin A for active food packaging. The release kinetics of Bifidocin A were studied, showing faster release at higher temperature and concentration, with endothermic and spontaneous release according to thermodynamic parameters. The results indicated that the composite films had better mechanical properties and anti-microbial activity at 50% Bifidocin A content, but inclusion of glycerol was necessary to prevent structural impairment.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2021)
Article
Food Science & Technology
Ruoning Zhang, Mengnan Cui, Jingjin Ye, Dongdong Yuan, Like Mao
Summary: Oleogel-in-water emulsions prepared using monoglyceride (GMS) oleogel as the oil phase and tween-20 (TW) as the emulsifier showed that an increase in emulsifier content led to decreased particle size, enhanced shearing viscosity and storage modulus. Emulsions with higher TW content exhibited minor size changes after thermal treatment, while an increase in ionic strength led to larger droplet size with TW inhibiting phase separation. The emulsions were stable over a pH range of 6 to 10, but significant increases in droplet size were seen after freeze-thaw cycles, with slight oiling off. Incorporating 13-carotene into the emulsions showed better retention in systems with higher TW content, even after thermal treatment or light exposure.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Applied
Dongdong Yuan, Xu Hao, Guorong Liu, Ying Yue, Jiaojiao Duan
Summary: A novel edible composite film was developed by incorporating a double emulsion into a chitosan film. The film exhibited persistent antibacterial activity and increased tensile strength. It displayed significant inhibitory effects on both Gram-positive and Gram-negative bacteria.
Article
Multidisciplinary Sciences
Daniel Mwangi Waweru, Joshua Mbaabu Arimi, Eunice Marete, Jean-Christophe Jacquier, Niamh Harbourne
Summary: This study chemically characterizes Dovyalis caffra and Dovyalis abyssinica fruits. The results showed that D. caffra had higher soluble solids, ascorbic acid content, and antioxidant activity, making it suitable for direct consumption. D. abyssinica had higher ash content and lower protein and fat contents.
Article
Agriculture, Multidisciplinary
Michelle Kearns, Jean-Christophe Jacquier, Sabine M. Harrison, Raquel Cama-Moncunill, Tommy M. Boland, Helen Sheridan, Alan K. Kelly, Simona Grasso, Frank J. Monahan
Summary: This study found that feeding steers a botanically-diverse diet consisting of six plant species can increase the n-3 fatty acid and polyunsaturated fatty acid concentration in beef, thereby affecting the susceptibility of cooked beef to oxidation.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.