Arginase: an emerging key player in the mammalian immune system

Arginine Deiminase as a Novel Therapy for Prostate Cancer Induces Autophagy and Caspase-Independent Apoptosis

(2009) R. H. Kim et al.   CANCER RESEARCH

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

(2008) K. Movahedi et al.   BLOOD

Characterization of Bacillus anthracis arginase: effects of pH, temperature, and cell viability on metal preference

(2008) Ryan J Viator et al.   BMC BIOCHEMISTRY

Airway epithelial cells modify immune responses by inducing an anti-inflammatory microenvironment

(2008) Anja K. Mayer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Th2 Cytokine-Induced Alterations in Intestinal Smooth Muscle Function Depend on Alternatively Activated Macrophages

(2008) Aiping Zhao et al.   GASTROENTEROLOGY

Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives

(2008) Paulo C. Rodríguez et al.   IMMUNOLOGICAL REVIEWS

Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase

(2008) Tawnya L. Bowles et al.   INTERNATIONAL JOURNAL OF CANCER

Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection

(2008) Abhishek Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

“Re-educating” tumor-associated macrophages by targeting NF-κB

(2008) Thorsten Hagemann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Arginase I Induction by Modified Lipoproteins in Macrophages: A Peroxisome Proliferator-Activated Receptor-γ/δ-Mediated Effect that Links Lipid Metabolism and Immunity

(2008) Alejandro Gallardo-Soler et al.   MOLECULAR ENDOCRINOLOGY

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY

Age-Related Alteration of Arginase Activity Impacts on Severity of Leishmaniasis

(2008) Ingrid Müller et al.   PLoS Neglected Tropical Diseases

Cationic Amino Acid Transporter-2 Regulates Immunity by Modulating Arginase Activity

(2008) Robert W. Thompson et al.   PLoS Pathogens

Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism

(2007) Edzard Schwedhelm et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Inhibition of NADPH oxidase by apocynin inhibits lipopolysaccharide (LPS) induced up-regulation of arginase in rat alveolar macrophages

(2007) Sonja Matthiesen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of arginase-1 expression in macrophages by a protein kinase a type I and histone deacetylase dependent pathway

(2007) Ivonne Haffner et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Red blood cell arginase suppresses Jurkat (T cell) proliferation by depleting arginine

(2007) Andrew Bernard et al.   SURGERY