Utilizing nutritional genomics to tailor diets for the prevention of cardiovascular disease: a guide for upcoming studies and implementations

Interaction of an S100A9 gene variant with saturated fat and carbohydrates to modulate insulin resistance in 3 populations of different ancestries

(2016) Ruth Blanco-Rojo et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Interactions between genetic variants associated with adiposity traits and soft drinks in relation to longitudinal changes in body weight and waist circumference

(2016) Nanna J Olsen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Genetic susceptibility to diabetes and long-term improvement of insulin resistance and β cell function during weight loss: the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial

(2016) Tao Huang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Sugar-sweetened beverage intake, chromosome 9p21 variants, and risk of myocardial infarction in Hispanics

(2016) Yan Zheng et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Multiple Healthful Dietary Patterns and Type 2 Diabetes in the Women's Health Initiative

(2016) Elizabeth M. Cespedes et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Association between parental history and genetic risk scores for coronary heart disease prediction: The population-based CoLaus study

(2016) Panagiotis Antiochos et al.   ATHEROSCLEROSIS

Reproducibility of data-driven dietary patterns in two groups of adult Spanish women from different studies

(2016) Adela Castelló et al.   BRITISH JOURNAL OF NUTRITION

Dairy consumption and CVD: a systematic review and meta-analysis

(2016) Dominik D. Alexander et al.   BRITISH JOURNAL OF NUTRITION

CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial

(2016) Dolores Corella et al.   Cardiovascular Diabetology

Opportunities for the Cardiovascular Community in the Precision Medicine Initiative: Table.

(2016) Svati H. Shah et al.   CIRCULATION

The American Heart Association’s New Institute for Precision Cardiovascular Medicine

(2016) Steven R. Houser   CIRCULATION

Are Genetic Tests for Atherosclerosis Ready for Routine Clinical Use?

(2016) Nina P. Paynter et al.   CIRCULATION RESEARCH

Genetics of Coronary Artery Disease

(2016) Ruth McPherson et al.   CIRCULATION RESEARCH

Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment

(2016) Jane F. Ferguson et al.   Circulation-Cardiovascular Genetics

Do Genetic Factors Modify the Relationship Between Obesity and Hypertriglyceridemia?CLINICAL PERSPECTIVE

(2016) Ashfaq Ali et al.   Circulation-Cardiovascular Genetics

Common and Rare Genetic Variation inCCR2,CCR5, orCX3CR1and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic TraitsCLINICAL PERSPECTIVE

(2016) Jessica R. Golbus et al.   Circulation-Cardiovascular Genetics

The importance of gene-environment interactions in human obesity

(2016) H. Reddon et al.   CLINICAL SCIENCE

Early nutrition, epigenetics, and cardiovascular disease

(2016) Elena Loche et al.   CURRENT OPINION IN LIPIDOLOGY

Genetic susceptibility to dyslipidemia and incidence of cardiovascular disease depending on a diet quality index in the Malmö Diet and Cancer cohort

(2016) Sophie Hellstrand et al.   Genes and Nutrition

Improved prediction of complex diseases by common genetic markers: state of the art and further perspectives

(2016) Bent Müller et al.   HUMAN GENETICS

A comparison of the dietary patterns derived by principal component analysis and cluster analysis in older Australians

(2016) Maree G. Thorpe et al.   International Journal of Behavioral Nutrition and Physical Activity

Familial hypercholesterolemia/autosomal dominant hypercholesterolemia: Molecular defects, the LDL-C continuum, and gradients of phenotypic severity

(2016) JoAnne M. Foody et al.   Journal of Clinical Lipidology

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant inANGPTL4determining fasting TG levels

(2016) Elisabeth M van Leeuwen et al.   JOURNAL OF MEDICAL GENETICS

Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition

(2016) Lynnette R. Ferguson et al.   Journal of Nutrigenetics and Nutrigenomics

Next generation sequencing: implications in personalized medicine and pharmacogenomics

(2016) Bahareh Rabbani et al.   Molecular BioSystems

Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease

(2016) Anna Helgadottir et al.   NATURE GENETICS

Precision medicine in cardiology

(2016) Elliott M. Antman et al.   Nature Reviews Cardiology

The role of diet and exercise in the transgenerational epigenetic landscape of T2DM

(2016) Romain Barrès et al.   Nature Reviews Endocrinology

Uncertainty in the Era of Precision Medicine

(2016) David J. Hunter   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

(2016) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

(2016) Fatima Cardoso et al.   NEW ENGLAND JOURNAL OF MEDICINE

The effect of interaction between Melanocortin-4 receptor polymorphism and dietary factors on the risk of metabolic syndrome

(2016) Gelareh Koochakpoor et al.   Nutrition & Metabolism

Marine n-3 polyunsaturated fatty acids lower plasma proprotein convertase subtilisin kexin type 9 levels in pre- and postmenopausal women: A randomised study

(2016) Christina B. Graversen et al.   VASCULAR PHARMACOLOGY

Does diet interact with genotype to cause epigenetic modification of angiogenesis genes, on the trajectory to obesity?

(2016) Joanna D Holbrook   Epigenomics

Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores

(2016) Dolores Corella et al.   Nutrients

Nutrition and Cardiovascular Disease: Finding the Perfect Recipe for Cardiovascular Health

(2016) Alice Ravera et al.   Nutrients

Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment

(2016) Jane F. Ferguson et al.   Circulation-Cardiovascular Genetics

Do Genetic Factors Modify the Relationship Between Obesity and Hypertriglyceridemia?CLINICAL PERSPECTIVE

(2016) Ashfaq Ali et al.   Circulation-Cardiovascular Genetics

Common and Rare Genetic Variation inCCR2,CCR5, orCX3CR1and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic TraitsCLINICAL PERSPECTIVE

(2016) Jessica R. Golbus et al.   Circulation-Cardiovascular Genetics

The association between adherence to the New Nordic Diet and diet quality

(2016) Helga Birgit Bjørnarå et al.   Food & Nutrition Research

Impact of Nonoptimal Intakes of Saturated, Polyunsaturated, and Trans Fat on Global Burdens of Coronary Heart Disease

(2016) Qianyi Wang et al.   Journal of the American Heart Association

Genetics and Genomics of Coronary Artery Disease

(2016) Milos Pjanic et al.   Current Cardiology Reports

Genetic susceptibility to dyslipidemia and incidence of cardiovascular disease depending on a diet quality index in the Malmö Diet and Cancer cohort

(2016) Sophie Hellstrand et al.   Genes and Nutrition

The US Food and Drug Administration and the Future of Cardiovascular Medicine

(2016) Mona Fiuzat et al.   JAMA Cardiology

Association of Empirically Derived Dietary Patterns with Cardiovascular Risk Factors: A Comparison of PCA and RRR Methods

(2016) Nicolas Sauvageot et al.   PLoS One

Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians

(2015) Amanda M Fretts et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Epigenetics in the Vascular EndotheliumSignificance

(2015) Matthew S. Yan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetics of cardiovascular disease: Importance of sex and ethnicity

(2015) Stacey J. Winham et al.   ATHEROSCLEROSIS

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

(2015) Chi-Fa Hung et al.   BMC Medicine

Dietary patterns interact with APOA1/APOC3 polymorphisms to alter the risk of the metabolic syndrome: the Tehran Lipid and Glucose Study

(2015) Firoozeh Hosseini-Esfahani et al.   BRITISH JOURNAL OF NUTRITION

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk FactorsNovelty and Significance

(2015) Marissa LeBlanc et al.   CIRCULATION RESEARCH

Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomised controlled trial

(2015)   DIABETOLOGIA

Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history

(2015) Hayato Tada et al.   EUROPEAN HEART JOURNAL

FTO gene variation, macronutrient intake and coronary heart disease risk: a gene–diet interaction analysis

(2015) Jaana Gustavsson et al.   EUROPEAN JOURNAL OF NUTRITION

Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry

(2015) Jennifer A. Nettleton et al.   HUMAN MOLECULAR GENETICS

Incremental predictive value of 152 single nucleotide polymorphisms in the 10-year risk prediction of incident coronary heart disease: the Rotterdam Study

(2015) P. S. de Vries et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genome-wide association studies of late-onset cardiovascular disease

(2015) J.Gustav Smith et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Dietary Patterns Methods Project: Synthesis of Findings across Cohorts and Relevance to Dietary Guidance

(2015) Angela D Liese et al.   JOURNAL OF NUTRITION

Use of genetic data to guide therapy in arterial disease

(2015) S. Ross et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Gene-diet interaction of a commonFADS1variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men

(2015) Markus J. Takkunen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

An integrated map of structural variation in 2,504 human genomes

(2015) Peter H. Sudmant et al.   NATURE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

A New Initiative on Precision Medicine

(2015) Francis S. Collins et al.   NEW ENGLAND JOURNAL OF MEDICINE

SLC2A9 Genotype Is Associated with SLC2A9 Gene Expression and Urinary Uric Acid Concentration

(2015) Erin B. Ware et al.   PLoS One

The Association between Carbohydrate-Rich Foods and Risk of Cardiovascular Disease Is Not Modified by Genetic Susceptibility to Dyslipidemia as Determined by 80 Validated Variants

(2015) Emily Sonestedt et al.   PLoS One

Role of Imaging in the Evaluation of Patients at Risk for Sudden Cardiac Death

(2015) Sherif F. Nagueh et al.   JACC-Cardiovascular Imaging

Diet Quality as Assessed by the Healthy Eating Index, the Alternate Healthy Eating Index, the Dietary Approaches to Stop Hypertension Score, and Health Outcomes: A Systematic Review and Meta-Analysis of Cohort Studies

(2015) Lukas Schwingshackl et al.   Journal of the Academy of Nutrition and Dietetics

MicroRNA-410 regulated lipoprotein lipase variant rs13702 is associated with stroke incidence and modulated by diet in the randomized controlled PREDIMED trial

(2014) Dolores Corella et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

How does the Mediterranean diet promote cardiovascular health? Current progress toward molecular mechanisms

(2014) Dolores Corella et al.   BIOESSAYS

The chromosome 9p21 variant interacts with vegetable and wine intake to influence the risk of cardiovascular disease: a population based cohort study

(2014) George Hindy et al.   BMC Medical Genetics

The association between Mediterranean Diet Score and glucokinase regulatory protein gene variation on the markers of cardiometabolic risk: an analysis in the European Prospective Investigation into Cancer (EPIC)-Norfolk study

(2014) Mercedes Sotos-Prieto et al.   BRITISH JOURNAL OF NUTRITION

SORT1 Protective Allele Is Associated With Attenuated Postprandial: Lipaemia in Young Adults

(2014) K. E. Connors et al.   Circulation-Cardiovascular Genetics

Amino Acid Change in the Carbohydrate Response Element Binding Protein Is Associated With Lower Triglycerides and Myocardial Infarction Incidence Depending on Level of Adherence to the Mediterranean Diet in the PREDIMED Trial

(2014) C. Ortega-Azorin et al.   Circulation-Cardiovascular Genetics

Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis of the Polygenic Form of Clinical Familial Hypercholesterolemia and Replication in Samples from 6 Countries

(2014) M. Futema et al.   CLINICAL CHEMISTRY

PCSK7Genotype Modifies Effect of a Weight-Loss Diet on 2-Year Changes of Insulin Resistance: The POUNDS LOST Trial

(2014) Tao Huang et al.   DIABETES CARE

Type 2 diabetes-related genetic risk scores associated with variations in fasting plasma glucose and development of impaired glucose homeostasis in the prospective DESIR study

(2014) Martine Vaxillaire et al.   DIABETOLOGIA

A genetic risk score for hypertension associates with the risk of ischemic stroke in a Swedish case–control study

(2014) Cristiano Fava et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The Challenge for the Next Generation of Medical Geneticists

(2014) Thierry Frebourg   HUMAN MUTATION

Genetic Variation in FADS1 Has Little Effect on the Association between Dietary PUFA Intake and Cardiovascular Disease

(2014) Sophie Hellstrand et al.   JOURNAL OF NUTRITION

Polymorphism at the TNF-alpha gene interacts with Mediterranean diet to influence triglyceride metabolism and inflammation status in metabolic syndrome patients: From the CORDIOPREV clinical trial

(2014) Francisco Gomez-Delgado et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Omega-3 fatty acids and the genetic risk of early onset acute coronary syndrome

(2014) S.S.L. Leung Yinko et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Interaction between Genetic Predisposition to Adiposity and Dietary Protein in Relation to Subsequent Change in Body Weight and Waist Circumference

(2014) Mikkel Z. Ankarfeldt et al.   PLoS One

Predicting Stroke Through Genetic Risk Functions

(2014) Carla A. Ibrahim-Verbaas et al.   STROKE

Saturated Fat Intake Modulates the Association between an Obesity Genetic Risk Score and Body Mass Index in Two US Populations

(2014) Patricia Casas-Agustench et al.   Journal of the Academy of Nutrition and Dietetics

Variants in glucose- and circadian rhythm–related genes affect the response of energy expenditure to weight-loss diets: the POUNDS LOST Trial

(2013) Khadijeh Mirzaei et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Egg consumption in relation to risk of cardiovascular disease and diabetes: a systematic review and meta-analysis

(2013) Jang Yel Shin et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Advances in Measuring the Effect of Individual Predictors of Cardiovascular Risk: The Role of Reclassification Measures

(2013) Nancy R. Cook et al.   ANNALS OF INTERNAL MEDICINE

Quantifying Diet for Nutrigenomic Studies

(2013) Katherine L. Tucker et al.   Annual Review of Nutrition

Multilocus Genetic Risk Scores for Coronary Heart Disease Prediction

(2013) Andrea Ganna et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Risk Scores of Common Genetic Variants for Lipid Levels Influence Atherosclerosis and Incident Coronary Heart Disease

(2013) Aaron Isaacs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetic predisposition to obesity and lifestyle factors – the combined analyses of twenty-six known BMI- and fourteen known waist:hip ratio (WHR)-associated variants in the Finnish Diabetes Prevention Study

(2013) Tiina Jääskeläinen et al.   BRITISH JOURNAL OF NUTRITION

Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence: A randomized controlled trial in a high-cardiovascular-risk population

(2013) D. Corella et al.   DIABETES CARE

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet

(2013) Ramón Estruch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease

(2013) Martin Dichgans et al.   STROKE

Egg consumption and risk of coronary heart disease and stroke: dose-response meta-analysis of prospective cohort studies

(2013) Y. Rong et al.   BMJ-British Medical Journal

Association of PLA2G4A with myocardial infarction is modulated by dietary PUFAs

(2012) Jaana Hartiala et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Meta-Analysis Investigating Associations Between Healthy Diet and Fasting Glucose and Insulin Levels and Modification by Loci Associated With Glucose Homeostasis in Data From 15 Cohorts

(2012) Jennifer A. Nettleton et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site

(2012) Kris Richardson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetics of Human Cardiovascular Disease

(2012) Sekar Kathiresan et al.   CELL

A Genetic Risk Score Is Associated With Incident Cardiovascular Disease and Coronary Artery Calcium

(2012) George Thanassoulis et al.   Circulation-Cardiovascular Genetics

Neuropeptide Y Promoter Polymorphism Modifies Effects of a Weight-Loss Diet on 2-Year Changes of Blood Pressure

(2012) Xiaomin Zhang et al.   HYPERTENSION

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

Sugar-Sweetened Beverages and Genetic Risk of Obesity

(2012) Qibin Qi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Statistical and Biological Gene-Lifestyle Interactions of MC4R and FTO with Diet and Physical Activity on Obesity: New Effects on Alcohol Consumption

(2012) Dolores Corella et al.   PLoS One

Influence of Dairy Product and Milk Fat Consumption on Cardiovascular Disease Risk: A Review of the Evidence

(2012) Peter J. Huth et al.   Advances in Nutrition

Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids

(2011) C.G. Walker et al.   ATHEROSCLEROSIS

Genetic variations at the lipoprotein lipase gene influence plasma lipid concentrations and interact with plasma n-6 polyunsaturated fatty acids to modulate lipid metabolism

(2011) Antonio Garcia-Rios et al.   ATHEROSCLEROSIS

A High Intake of Saturated Fatty Acids Strengthens the Association between the Fat Mass and Obesity-Associated Gene and BMI

(2011) Dolores Corella et al.   JOURNAL OF NUTRITION

A Short Screener Is Valid for Assessing Mediterranean Diet Adherence among Older Spanish Men and Women

(2011) Helmut Schröder et al.   JOURNAL OF NUTRITION

The PLIN4 Variant rs8887 Modulates Obesity Related Phenotypes in Humans through Creation of a Novel miR-522 Seed Site

(2011) Kris Richardson et al.   PLoS One

Effect of interaction between PPARG, PPARA and ADIPOQ gene variants and dietary fatty acids on plasma lipid profile and adiponectin concentration in a large intervention study

(2011) Aseel AlSaleh et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

The Effect of Chromosome 9p21 Variants on Cardiovascular Disease May Be Modified by Dietary Intake: Evidence from a Case/Control and a Prospective Study

(2011) Ron Do et al.   PLOS MEDICINE

Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease

(2010) Dawn M. Waterworth et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dietary Guidelines in the 21st Century—a Time for Food

(2010) Dariush Mozaffarian et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association Between a Literature-Based Genetic Risk Score and Cardiovascular Events in Women

(2010) Nina P. Paynter   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

APOA2, Dietary Fat, and Body Mass Index

(2009) Dolores Corella   ARCHIVES OF INTERNAL MEDICINE

Nutrigenomics in Cardiovascular Medicine

(2009) Dolores Corella et al.   Circulation-Cardiovascular Genetics

Learning from the Past and Looking to the Future

(2009) Alexander M. Capron   Journal of Nutrigenetics and Nutrigenomics

Genetic Predisposition, Nongenetic Risk Factors, and Coronary Infarct

(2008) Antonia Trichopoulou et al.   ARCHIVES OF INTERNAL MEDICINE

Carbohydrate intake modifies associations between ANGPTL4[E40K] genotype and HDL-cholesterol concentrations in White men from the Atherosclerosis Risk in Communities (ARIC) study

(2008) Jennifer A. Nettleton et al.   ATHEROSCLEROSIS

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events

(2008) Sekar Kathiresan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Session 2: Personalised nutrition Epigenomics: a basis for understanding individual differences?

(2008) John C. Mathers   PROCEEDINGS OF THE NUTRITION SOCIETY