Statistical and Biological Gene-Lifestyle Interactions of MC4R and FTO with Diet and Physical Activity on Obesity: New Effects on Alcohol Consumption

β2-Adrenergic Receptor Thr164Ile Polymorphism, Obesity, and Diabetes: Comparison withFTO,MC4R, andTMEM18Polymorphisms in More Than 64,000 Individuals

(2012) Mette Thomsen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

High Dietary Saturated Fat Intake Accentuates Obesity Risk Associated with the Fat Mass and Obesity–Associated Gene in Adults

(2012) Catherine M. Phillips et al.   JOURNAL OF NUTRITION

Association Between FTO Variant and Change in Body Weight and Its Interaction With Dietary Factors: The DiOGenes Study

(2012) Karani S. Vimaleswaran et al.   Obesity

The Effect of Elevated Body Mass Index on Ischemic Heart Disease Risk: Causal Estimates from a Mendelian Randomisation Approach

(2012) Børge G. Nordestgaard et al.   PLOS MEDICINE

Assessment of Voluntary Ethanol Consumption and the Effects of a Melanocortin (MC) Receptor Agonist on Ethanol Intake in Mutant C57BL/6J Mice Lacking the MC-4 Receptor

(2011) Montserrat Navarro et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Influence of Physical Inactivity on Associations Between Single Nucleotide Polymorphisms and Genetic Predisposition to Childhood Obesity

(2011) B. Xi et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

FTO gene polymorphisms and obesity risk: a meta-analysis

(2011) Sihua Peng et al.   BMC Medicine

FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life: A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies

(2011) J. K. Hertel et al.   DIABETES

Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians

(2011) H. Li et al.   DIABETOLOGIA

Characterization of the Hyperphagic Response to Dietary Fat in the MC4R Knockout Mouse

(2011) Dollada Srisai et al.   ENDOCRINOLOGY

Influence of common variants in FTO and near INSIG2 and MC4R on growth curves for adiposity in African– and European–American youth

(2011) Gaifen Liu et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

The genetic epidemiology of melanocortin 4 receptor variants

(2011) Ruth J.F. Loos   EUROPEAN JOURNAL OF PHARMACOLOGY

A High Intake of Saturated Fatty Acids Strengthens the Association between the Fat Mass and Obesity-Associated Gene and BMI

(2011) Dolores Corella et al.   JOURNAL OF NUTRITION

A Short Screener Is Valid for Assessing Mediterranean Diet Adherence among Older Spanish Men and Women

(2011) Helmut Schröder et al.   JOURNAL OF NUTRITION

Common Variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 Show Evidence of Association With Adult Obesity in the Greek Population

(2011) Konstantinos Rouskas et al.   Obesity

Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children

(2011) Tuomas O. Kilpeläinen et al.   PLOS MEDICINE

Inverse association of the obesity predisposing FTO rs9939609 genotype with alcohol consumption and risk for alcohol dependence

(2010) Agnieszka Sobczyk-Kopciol et al.   ADDICTION

FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth

(2010) Gaifen Liu et al.   BMC Medical Genetics

Relative validity of a semi-quantitative food-frequency questionnaire in an elderly Mediterranean population of Spain

(2010) Joan D. Fernández-Ballart et al.   BRITISH JOURNAL OF NUTRITION

The Meaning of Interaction

(2010) Xuefeng Wang et al.   HUMAN HEREDITY

Cohort Profile: Design and methods of the PREDIMED study

(2010) M. A. Martinez-Gonzalez et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Obesity due to Melanocortin 4 Receptor (MC4R) Deficiency Is Associated with Increased Linear Growth and Final Height, Fasting Hyperinsulinemia, and Incompletely Suppressed Growth Hormone Secretion

(2010) Carlos E. Martinelli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A Variant in the Fat Mass and Obesity-Associated Gene (FTO) and Variants near the Melanocortin-4 Receptor Gene (MC4R) Do Not Influence Dietary Intake

(2010) Ann L. Hasselbalch et al.   JOURNAL OF NUTRITION

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

Statistical interaction in human genetics: how should we model it if we are looking for biological interaction?

(2010) Xuefeng Wang et al.   NATURE REVIEWS GENETICS

Education modulates the association of the FTO rs9939609 polymorphism with body mass index and obesity risk in the Mediterranean population

(2010) D. Corella et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Melanocortin activity in the amygdala influences alcohol intake

(2010) D.A. York et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

(2010) Yi-Chun Loraine Tung et al.   PLoS One

Influence of common variants near INSIG2, in FTO, and near MC4R genes on overweight and the metabolic profile in adolescence: the TRAILS (TRacking Adolescents’ Individual Lives Survey) Study

(2009) Eryn T Liem et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Evidence that multiple genetic variants of MC4R play a functional role in the regulation of energy expenditure and appetite in Hispanic children

(2009) Shelley A Cole et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity

(2009) Emily Sonestedt et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Prevalence of pathogenetic MC4R mutations in Italian children with early Onset obesity, tall stature and familial history of obesity

(2009) Nicola Santoro et al.   BMC Medical Genetics

Nutrigenomics in Cardiovascular Medicine

(2009) Dolores Corella et al.   Circulation-Cardiovascular Genetics

Life course variations in the associations between FTO and MC4R gene variants and body size

(2009) R. Hardy et al.   HUMAN MOLECULAR GENETICS

FTO Genotype Is Associated with Body Mass Index after the Age of Seven Years But Not with Energy Intake or Leisure-Time Physical Activity

(2009) Maarit Hakanen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations

(2009) Stéphane Cauchi et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Physical Activity and the Association of Common FTO Gene Variants With Body Mass Index and Obesity

(2008) Evadnie Rampersaud et al.   ARCHIVES OF INTERNAL MEDICINE

Gene–environment interactions for complex traits: definitions, methodological requirements and challenges

(2008) Astrid Dempfle et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Variation in the FTO Gene Influences Food Intake but not Energy Expenditure

(2008) A. Haupt et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women

(2008) L. Qi et al.   HUMAN MOLECULAR GENETICS

Common genetic variants at the MC4R locus are associated with obesity, but not with dietary energy intake or colorectal cancer in the Scottish population

(2008) A Tenesa et al.   INTERNATIONAL JOURNAL OF OBESITY

Common variants near MC4R are associated with fat mass, weight and risk of obesity

(2008) Ruth J F Loos et al.   NATURE GENETICS

An Obesity-AssociatedFTOGene Variant and Increased Energy Intake in Children

(2008) Joanne E. Cecil et al.   NEW ENGLAND JOURNAL OF MEDICINE