When evolution is the solution to pollution: Key principles, and lessons from rapid repeated adaptation of killifish (Fundulus heteroclitus ) populations

Impacts of Petroleum-Derived Pollutants on Fish Development

(2017) Gary N. Cherr et al.   Annual Review of Animal Biosciences

Cross-resistance in Gulf killifish (Fundulus grandis) populations resistant to dioxin-like compounds

(2016) Elias M. Oziolor et al.   AQUATIC TOXICOLOGY

Integrating Monitoring and Genetic Methods To Infer Historical Risks of PCBs and DDE to Common and Roseate Terns Nesting Near the New Bedford Harbor Superfund Site (Massachusetts, USA)

(2016) Diane E. Nacci et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The probability of parallel genetic evolution from standing genetic variation

(2016) A. MacPherson et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Genetic basis for rapidly evolved tolerance in the wild: adaptation to toxic pollutants by an estuarine fish species

(2016) Diane Nacci et al.   MOLECULAR ECOLOGY

The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish

(2016) N. M. Reid et al.   SCIENCE

Can Population Genetics Adapt to Rapid Evolution?

(2016) Philipp W. Messer et al.   TRENDS IN GENETICS

AhR signaling activation disrupts migration and dendritic growth of olfactory interneurons in the developing mouse

(2016) Eiki Kimura et al.   Scientific Reports

Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure

(2016) S. C. T. Nicklisch et al.   Science Advances

Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA

(2015) Erika B. Fritsch et al.   AQUATIC TOXICOLOGY

Regulation of pregnane-X-receptor, CYP3A and P-glycoprotein genes in the PCB-resistant killifish (Fundulus heteroclitus) population from New Bedford Harbor

(2015) Johanna Gräns et al.   AQUATIC TOXICOLOGY

The Elizabeth River Story: A Case Study in Evolutionary Toxicology

(2015) Richard T. Di Giulio et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Genetic compensation induced by deleterious mutations but not gene knockdowns

(2015) Andrea Rossi et al.   NATURE

Mutation and duplication of arthropod acetylcholinesterase: Implications for pesticide resistance and tolerance

(2015) Si Hyeock Lee et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Ah receptor pathway intricacies; signaling through diverse protein partners and DNA-motifs

(2015) D. P. Jackson et al.   Toxicology Research

The Ah receptor in stem cell cycling, regulation, and quiescence

(2014) Thomas A. Gasiewicz et al.   Annals of the New York Academy of Sciences

The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

(2014) Brigitta Stockinger et al.   Annual Review of Immunology

Evolved resistance to PCB- and PAH-induced cardiac teratogenesis, and reduced CYP1A activity in Gulf killifish (Fundulus grandis) populations from the Houston Ship Channel, Texas

(2014) Elias M. Oziolor et al.   AQUATIC TOXICOLOGY

Chronic exposure of killifish to a highly polluted environment desensitizes estrogen-responsive reproductive and biomarker genes

(2014) Sean M. Bugel et al.   AQUATIC TOXICOLOGY

Targeted approach to identify genetic loci associated with evolved dioxin tolerance in Atlantic Killifish (Fundulus heteroclitus)

(2014) Dina A Proestou et al.   BMC EVOLUTIONARY BIOLOGY

Genetic variation at aryl hydrocarbon receptor (AHR) loci in populations of Atlantic killifish (Fundulus heteroclitus) inhabiting polluted and reference habitats

(2014) Adam M Reitzel et al.   BMC EVOLUTIONARY BIOLOGY

Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists

(2014) Daniel R. Brown et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

(2014) Alban Bessede et al.   NATURE

AhR sensing of bacterial pigments regulates antibacterial defence

(2014) Pedro Moura-Alves et al.   NATURE

PNAS Plus: From the Cover: Deepwater Horizon crude oil impacts the developing hearts of large predatory pelagic fish

(2014) J. P. Incardona et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crude Oil Impairs Cardiac Excitation-Contraction Coupling in Fish

(2014) F. Brette et al.   SCIENCE

The Genomic Landscape of Compensatory Evolution

(2014) Béla Szamecz et al.   PLOS BIOLOGY

The Population Genetics of Evolutionary Rescue

(2014) H. Allen Orr et al.   PLoS Genetics

Genomic Evidence of Rapid and Stable Adaptive Oscillations over Seasonal Time Scales in Drosophila

(2014) Alan O. Bergland et al.   PLoS Genetics

A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector

(2014) Jacob M Riveron et al.   GENOME BIOLOGY

Genomic and physiological responses to strong selective pressure during late organogenesis: few gene expression changes found despite striking morphological differences

(2013) Goran Bozinovic et al.   BMC GENOMICS

Differential sensitivity to pro-oxidant exposure in two populations of killifish (Fundulus heteroclitus)

(2013) Rachel C. Harbeitner et al.   ECOTOXICOLOGY

The Molecular Genetics of Insecticide Resistance

(2013) Richard H. ffrench-Constant   GENETICS

Bioaccumulation of polychlorinated biphenyls and organochlorine pesticides in young-of-the-year bluefish (Pomatomus saltatrix) in the vicinity of a Superfund Site in New Bedford Harbor, Massachusetts, and in the adjacent waters

(2013) Ashok D. Deshpande et al.   MARINE POLLUTION BULLETIN

Evolutionary rescue from extinction is contingent on a lower rate of environmental change

(2013) Haley A. Lindsey et al.   NATURE

Loss of Aryl Hydrocarbon Receptor Promotes Gene Changes Associated with Premature Hematopoietic Stem Cell Exhaustion and Development of a Myeloproliferative Disorder in Aging Mice

(2013) Kameshwar P. Singh et al.   STEM CELLS AND DEVELOPMENT

Regulation of zebrafish CYP3A65 transcription by AHR2

(2013) Chin-Teng Chang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression

(2012) Timothy V. Beischlag et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Inhibition of cellular efflux pumps involved in multi xenobiotic resistance (MXR) in echinoid larvae as a possible mode of action for increased ecotoxicological risk of mixtures

(2012) Henrique M. R. Anselmo et al.   ECOTOXICOLOGY

Impact of environment on mosquito response to pyrethroid insecticides: Facts, evidences and prospects

(2012) Theresia Estomih Nkya et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Evolutionary rescue and the limits of adaptation

(2012) G. Bell   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

AHR2 Mutant Reveals Functional Diversity of Aryl Hydrocarbon Receptors in Zebrafish

(2012) Britton C. Goodale et al.   PLoS One

Amino Acid Sequence of the Ligand-Binding Domain of the Aryl Hydrocarbon Receptor 1 Predicts Sensitivity of Wild Birds to Effects of Dioxin-Like Compounds

(2012) Reza Farmahin et al.   TOXICOLOGICAL SCIENCES

Decreased vitellogenin inducibility and 17β-estradiol levels correlated with reduced egg production in killifish (Fundulus heteroclitus) from Newark Bay, NJ

(2011) Sean M. Bugel et al.   AQUATIC TOXICOLOGY

Transcriptomic assessment of resistance to effects of an aryl hydrocarbon receptor (AHR) agonist in embryos of Atlantic killifish (Fundulus heteroclitus) from a marine Superfund site

(2011) Marjorie F Oleksiak et al.   BMC GENOMICS

Fundulus heteroclitus adapted to PAHs are cross-resistant to multiple insecticides

(2011) Bryan W. Clark et al.   ECOTOXICOLOGY

Quantitative genetics approaches to study evolutionary processes in ecotoxicology; a perspective from research on the evolution of resistance

(2011) Paul L. Klerks et al.   ECOTOXICOLOGY

Differential resistance of insect sodium channels with kdr mutations to deltamethrin, permethrin and DDT

(2011) Mark J. Burton et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

AIP and its interacting partners

(2011) Giampaolo Trivellin et al.   JOURNAL OF ENDOCRINOLOGY

Reproductive and developmental toxicity of dioxin in fish

(2011) Tisha C. King-Heiden et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ecologically and Evolutionarily Important SNPs Identified in Natural Populations

(2011) L. M. Williams et al.   MOLECULAR BIOLOGY AND EVOLUTION

Gene amplification and insecticide resistance

(2011) Chris Bass et al.   PEST MANAGEMENT SCIENCE

A Dominant Negative Zebrafish Ahr2 Partially Protects Developing Zebrafish from Dioxin Toxicity

(2011) Kevin A. Lanham et al.   PLoS One

Genomic mechanisms of evolved physiological plasticity in killifish distributed along an environmental salinity gradient

(2011) A. Whitehead et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common mechanism underlies repeated evolution of extreme pollution tolerance

(2011) A. Whitehead et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mechanistic Basis of Resistance to PCBs in Atlantic Tomcod from the Hudson River

(2011) I. Wirgin et al.   SCIENCE

Genetic Architecture of Susceptibility to PCB126-Induced Developmental Cardiotoxicity in Zebrafish

(2011) Eric R. Waits et al.   TOXICOLOGICAL SCIENCES

Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

(2011) Michael S. Denison et al.   TOXICOLOGICAL SCIENCES

Cardiac toxicity of 5-ring polycyclic aromatic hydrocarbons is differentially dependent on the aryl hydrocarbon receptor 2 isoform during zebrafish development

(2011) John P. Incardona et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mammalian Per-Arnt-Sim Proteins in Environmental Adaptation

(2010) Brian E. McIntosh et al.   Annual Review of Physiology

Embryonic gene expression among pollutant resistant and sensitive Fundulus heteroclitus populations

(2010) Goran Bozinovic et al.   AQUATIC TOXICOLOGY

Estrogen responses in killifish (Fundulus heteroclitus) from polluted and unpolluted environments are site- and gene-specific

(2010) Sarah R. Greytak et al.   AQUATIC TOXICOLOGY

AHR2 mediates cardiac teratogenesis of polycyclic aromatic hydrocarbons and PCB-126 in Atlantic killifish (Fundulus heteroclitus)

(2010) Bryan W. Clark et al.   AQUATIC TOXICOLOGY

Endocrine Disrupting Chemicals Targeting Estrogen Receptor Signaling: Identification and Mechanisms of Action

(2010) Erin K. Shanle et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Adaptation of the Estuarine Fish Fundulus heteroclitus (Atlantic Killifish) to Polychlorinated Biphenyls (PCBs)

(2010) Diane E. Nacci et al.   Estuaries and Coasts

The Aryl Hydrocarbon Receptor-interacting Protein (AIP) Is Required for Dioxin-induced Hepatotoxicity but Not for the Induction of theCyp1a1andCyp1a2Genes

(2010) Manabu Nukaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative transcriptomics implicates mechanisms of evolved pollution tolerance in a killifish population

(2010) A. WHITEHEAD et al.   MOLECULAR ECOLOGY

Aryl Hydrocarbon Receptor Nuclear Translocator in Hepatocytes Is Required for Aryl Hydrocarbon Receptor–Mediated Adaptive and Toxic Responses in Liver

(2010) Manabu Nukaya et al.   TOXICOLOGICAL SCIENCES

Pest Toxicology: The Primary Mechanisms of Pesticide Action

(2009) John E. Casida   CHEMICAL RESEARCH IN TOXICOLOGY

Evolutionary rescue can prevent extinction following environmental change

(2009) Graham Bell et al.   ECOLOGY LETTERS

Drug Discovery Using Chemical Systems Biology: Identification of the Protein-Ligand Binding Network To Explain the Side Effects of CETP Inhibitors

(2009) Li Xie et al.   PLoS Computational Biology

Fitness Costs of Insect Resistance toBacillus thuringiensis

(2008) Aaron J. Gassmann et al.   Annual Review of Entomology

Changes in gene expression due to chronic exposure to environmental pollutants

(2008) Marjorie F. Oleksiak   AQUATIC TOXICOLOGY

Development of the morpholino gene knockdown technique in Fundulus heteroclitus: A tool for studying molecular mechanisms in an established environmental model

(2008) C MATSON et al.   AQUATIC TOXICOLOGY

The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways

(2008) Alvaro Puga et al.   BIOCHEMICAL PHARMACOLOGY

Evolution of tolerance to PCBs and susceptibility to a bacterial pathogen (Vibrio harveyi) in Atlantic killifish (Fundulus heteroclitus) from New Bedford (MA, USA) harbor

(2008) Diane Nacci et al.   ENVIRONMENTAL POLLUTION

Relative influences of historical and contemporary forces shaping the distribution of genetic variation in the Atlantic killifish, Fundulus heteroclitus

(2008) DAVID D. DUVERNELL et al.   MOLECULAR ECOLOGY

Detecting genetic responses to environmental change

(2008) Ary A. Hoffmann et al.   NATURE REVIEWS GENETICS

A Possible Role of Multidrug Resistance–Associated Protein 2 (Mrp2) in Hepatic Excretion of PCB126, an Environmental Contaminant: PBPK/PD Modeling

(2008) Manupat Lohitnavy et al.   TOXICOLOGICAL SCIENCES

Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

(2008) Maureen K. Bunger et al.   TOXICOLOGICAL SCIENCES

Adaptation from standing genetic variation

(2007) R BARRETT et al.   TRENDS IN ECOLOGY & EVOLUTION