Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression

(2012) Timothy V. Beischlag et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cells

(2011) Edward Dere et al.   BMC GENOMICS

Genome-Wide Computational Analysis of Dioxin Response Element Location and Distribution in the Human, Mouse, and Rat Genomes

(2011) Edward Dere et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis—Persistent pollutants affect programmed cell death

(2011) Martin Chopra et al.   CRITICAL REVIEWS IN TOXICOLOGY

Identification of a High-Affinity Ligand That Exhibits Complete Aryl Hydrocarbon Receptor Antagonism

(2011) K. J. Smith et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Thiol-Based Redox Switches and Gene Regulation

(2010) Haike Antelmann et al.   ANTIOXIDANTS & REDOX SIGNALING

The aryl hydrocarbon receptor nuclear translocator-interacting protein 2 suppresses the estrogen receptor signaling via an Arnt-dependent mechanism

(2010) Yanjie Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells

(2010) Leslie M. Tompkins et al.   BIOCHEMICAL PHARMACOLOGY

Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation

(2010) Stéphane Pierre et al.   BIOCHEMICAL PHARMACOLOGY

Aryl Hydrocarbon Receptor Functions as a Potent Coactivator of E2F1-Dependent Trascription Activity

(2010) Yuichi Watabe et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Development of a Selective Modulator of Aryl Hydrocarbon (Ah) Receptor Activity that Exhibits Anti-Inflammatory Properties

(2010) Iain A. Murray et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cytochrome P450 1A1 gene regulation by UVB involves crosstalk between the aryl hydrocarbon receptor and nuclear factor κB

(2010) S. Luecke et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dioxins, the aryl hydrocarbon receptor and the central regulation of energy balance

(2010) Jere Lindén et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Identification of the Aryl Hydrocarbon Receptor Target GeneTiPARPas a Mediator of Suppression of Hepatic Gluconeogenesis by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and of Nicotinamide as a Corrective Agent for This Effect

(2010) Silvia Diani-Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Glucocorticoid Receptor modulators

(2010) Karolien De Bosscher   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Amino Acid Substitutions in the Aryl Hydrocarbon Receptor Ligand Binding Domain Reveal YH439 As an Atypical AhR Activator

(2010) F. Whelan et al.   MOLECULAR PHARMACOLOGY

Suppression of Cytokine-Mediated Complement Factor Gene Expression through Selective Activation of the Ah Receptor with 3',4'-Dimethoxy- -naphthoflavone

(2010) I. A. Murray et al.   MOLECULAR PHARMACOLOGY

Mechanism-based common reactivity pattern (COREPA) modelling of aryl hydrocarbon receptor binding affinity

(2010) P.I. Petkov et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

(2010) Anthony E. Boitano et al.   SCIENCE

Differential Gene Regulation by the Human and Mouse Aryl Hydrocarbon Receptor

(2010) Colin A. Flaveny et al.   TOXICOLOGICAL SCIENCES

Automated Dose-Response Analysis and Comparative Toxicogenomic Evaluation of the Hepatic Effects Elicited by TCDD, TCDF, and PCB126 in C57BL/6 Mice

(2010) Anna K. Kopec et al.   TOXICOLOGICAL SCIENCES

CH223191 Is a Ligand-Selective Antagonist of the Ah (Dioxin) Receptor

(2010) Bin Zhao et al.   TOXICOLOGICAL SCIENCES

3-Methylcholanthrene Induces Differential Recruitment of Aryl Hydrocarbon Receptor to Human Promoters

(2010) Andrea Pansoy et al.   TOXICOLOGICAL SCIENCES

Cytochrome P4501A1 Is Required for Vascular Dysfunction and Hypertension Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

(2010) Phillip G. Kopf et al.   TOXICOLOGICAL SCIENCES

An Integrated Genomic Analysis of Aryl Hydrocarbon Receptor-Mediated Inhibition of B-Cell Differentiation

(2010) K. Nadira De Abrew et al.   TOXICOLOGICAL SCIENCES

Aryl Hydrocarbon Receptor Nuclear Translocator in Hepatocytes Is Required for Aryl Hydrocarbon Receptor–Mediated Adaptive and Toxic Responses in Liver

(2010) Manabu Nukaya et al.   TOXICOLOGICAL SCIENCES

Kynurenic Acid Is a Potent Endogenous Aryl Hydrocarbon Receptor Ligand that Synergistically Induces Interleukin-6 in the Presence of Inflammatory Signaling

(2010) Brett C. DiNatale et al.   TOXICOLOGICAL SCIENCES

Detection of the TCDD Binding-Fingerprint within the Ah Receptor Ligand Binding Domain by Structurally Driven Mutagenesis and Functional Analysis

(2009) Alessandro Pandini et al.   BIOCHEMISTRY

The Uremic Toxin 3-Indoxyl Sulfate Is a Potent Endogenous Agonist for the Human Aryl Hydrocarbon Receptor

(2009) Jennifer C. Schroeder et al.   BIOCHEMISTRY

Differential Presentation of Protein Interaction Surfaces on the Androgen Receptor Defines the Pharmacological Actions of Bound Ligands

(2009) John David Norris et al.   CHEMISTRY & BIOLOGY

Hormonal regulation of CYP1A expression

(2009) Katalin Monostory et al.   DRUG METABOLISM REVIEWS

High-throughput evaluation of aryl hydrocarbon receptor-binding sites selected via chromatin immunoprecipitation-based screening in Hepa-1c1c7 cells stimulated with 2,3,7,8-tetrachlorodibenzo-p-dioxin

(2009) Masaki Kinehara et al.   GENES & GENETIC SYSTEMS

The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

(2009) Emily A. Stevens et al.   IMMUNOLOGY

2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Induces Calcium Influx Through T-type Calcium Channel and Enhances Lysosomal Exocytosis and Insulin Secretion in INS-1 Cells

(2009) Youn-Hee Kim et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Aryl hydrocarbon receptor-mediated induction of the cytosolic phospholipase A2α gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse hepatoma Hepa-1c1c7 cells

(2009) Masaki Kinehara et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

An Overview of the Effects of Dioxins and Dioxin-Like Compounds on Vertebrates, as Documented in Human and Ecological Epidemiology

(2009) SALLY S. WHITE et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands

(2009) William H. Bisson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evidence for Ligand-Mediated Selective Modulation of Aryl Hydrocarbon Receptor Activity

(2009) I. A. Murray et al.   MOLECULAR PHARMACOLOGY

Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity

(2009) L -C Bui et al.   ONCOGENE

The pleiotropy of dioxin toxicity — Xenobiotic misappropriation of the aryl hydrocarbon receptor's alternative physiological roles

(2009) Sebastian G.B. Furness et al.   PHARMACOLOGY & THERAPEUTICS

Dioxin-Dependent and Dioxin-Independent Gene Batteries: Comparison of Liver and Kidney in AHR-Null Mice

(2009) Paul C. Boutros et al.   TOXICOLOGICAL SCIENCES

Dioxin Increases the Interaction Between Aryl Hydrocarbon Receptor and Estrogen Receptor Alpha at Human Promoters

(2009) Shaimaa Ahmed et al.   TOXICOLOGICAL SCIENCES

AhR and ARNT modulate ER signaling

(2009) Elin Swedenborg et al.   TOXICOLOGY

Molecular determinants of species-specific agonist and antagonist activity of a substituted flavone towards the aryl hydrocarbon receptor

(2008) E.C. Henry et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The mouse and human Ah receptor differ in recognition of LXXLL motifs

(2008) Colin Flaveny et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Phosphodiesterases link the aryl hydrocarbon receptor complex to cyclic nucleotide signaling

(2008) Simone Kobe de Oliveira et al.   BIOCHEMICAL PHARMACOLOGY

Ah receptor and NF-κB interplay on the stage of epigenome

(2008) Yanan Tian   BIOCHEMICAL PHARMACOLOGY

Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways

(2008) Thomas Haarmann-Stemmann et al.   BIOCHEMICAL PHARMACOLOGY

AHR-mediated immunomodulation: The role of altered gene transcription

(2008) Nancy I. Kerkvliet   BIOCHEMICAL PHARMACOLOGY

Regulation of constitutive and inducible AHR signaling: Complex interactions involving the AHR repressor

(2008) Mark E. Hahn et al.   BIOCHEMICAL PHARMACOLOGY

The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways

(2008) Alvaro Puga et al.   BIOCHEMICAL PHARMACOLOGY

The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects

(2008) Fumio Matsumura   BIOCHEMICAL PHARMACOLOGY

Significance of the Nongenomic, Inflammatory Pathway in Mediating the Toxic Action of TCDD To Induce Rapid and Long-Term Cellular Responses in 3T3-L1 Adipocytes†

(2008) Wen Li et al.   BIOCHEMISTRY

Role of mitogen-activated protein kinases in aryl hydrocarbon receptor signaling

(2008) Pavla Henklová et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dioxins and Cardiovascular Disease Mortality

(2008) Olivier Humblet et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Prevalence of Metabolic Syndrome Associated with Body Burden Levels of Dioxin and Related Compounds among Japan’s General Population

(2008) Hirokazu Uemura et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Commentary on the association of polychlorinated biphenyls with hypertension

(2008) C.J. Everett et al.   ENVIRONMENTAL RESEARCH

Key Amino Acids in the Aryl Hydrocarbon Receptor Predict Dioxin Sensitivity in Avian Species

(2008) Jessica A. Head et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The Suggested Physiologic Aryl Hydrocarbon Receptor Activator and Cytochrome P4501 Substrate 6-Formylindolo[3,2-b]carbazole Is Present in Humans

(2008) Emma Wincent et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the Per/Arnt/Sim Domains in Ligand-dependent Transformation of the Aryl Hydrocarbon Receptor

(2008) Anatoly Soshilov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dioxin-mediated tumor progression through activation of mitochondria-to-nucleus stress signaling

(2008) G. Biswas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

(2008) Maureen K. Bunger et al.   TOXICOLOGICAL SCIENCES

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

(2007) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Molecular mechanisms of p21 and p27 induction by 3-methylcholanthrene, an aryl-hydrocarbon receptor agonist, involved in antiproliferation of human umbilical vascular endothelial cells

(2007) Pai-Huei Pang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Transcription Factor Aryl Hydrocarbon Receptor Nuclear Translocator Functions as an Estrogen Receptor β-Selective Coactivator, and Its Recruitment to Alternative Pathways Mediates Antiestrogenic Effects of Dioxin

(2007) Joëlle Rüegg et al.   MOLECULAR ENDOCRINOLOGY

Ligand-dependent interactions of the Ah receptor with coactivators in a mammalian two-hybrid assay

(2007) Shu Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY