Emerging Roles for MicroRNAs in Diabetic Microvascular Disease: Novel Targets for Therapy

Recent progress toward the use of circulating microRNAs as clinical biomarkers

(2016) Vikas Ghai et al.   ARCHIVES OF TOXICOLOGY

MicroRNA-181b Improves Glucose Homeostasis and Insulin Sensitivity by Regulating Endothelial Function in White Adipose TissueNovelty and Significance

(2016) Xinghui Sun et al.   CIRCULATION RESEARCH

Plasticity of Arterial and Venous Endothelial Cell Identity

(2016) Basak Icli et al.   CIRCULATION RESEARCH

MicroRNA Regulation of Atherosclerosis

(2016) Mark W. Feinberg et al.   CIRCULATION RESEARCH

Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?

(2016) F. Prattichizzo et al.   DIABETES OBESITY & METABOLISM

MicroRNA-181b inhibits thrombin-mediated endothelial activation and arterial thrombosis by targeting caspase recruitment domain family member 10

(2016) Jibin Lin et al.   FASEB JOURNAL

miR-204 Targets PERK and Regulates UPR Signaling and β-Cell Apoptosis

(2016) Guanlan Xu et al.   MOLECULAR ENDOCRINOLOGY

Anti–Vascular Endothelial Growth Factor Agents in the Treatment of Retinal Disease

(2016) Peter A. Campochiaro et al.   OPHTHALMOLOGY

miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy

(2016) Shawn S. Badal et al.   Nature Communications

Vascular microRNA-204 is remotely governed by the microbiome and impairs endothelium-dependent vasorelaxation by downregulating Sirtuin1

(2016) Ajit Vikram et al.   Nature Communications

miR‐342‐5p Is a Notch Downstream Molecule and Regulates Multiple Angiogenic Pathways Including Notch, Vascular Endothelial Growth Factor and Transforming Growth Factor β Signaling

(2016) Xian‐Chun Yan et al.   Journal of the American Heart Association

E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis

(2016) Shuangtao Ma et al.   Scientific Reports

MicroRNA-130b improves renal tubulointerstitial fibrosis via repression of Snail-induced epithelial-mesenchymal transition in diabetic nephropathy

(2016) Xiaoyan Bai et al.   Scientific Reports

Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE–/– Mice

(2015) Azadeh Kheirolomoom et al.   ACS Nano

Impairment of Wound Healing in Patients With Type 2 Diabetes Mellitus Influences Circulating MicroRNA Patterns via Inflammatory Cytokines

(2015) S. Dangwal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Altered microRNAs expression profiling in mice with diabetic neuropathic pain

(2015) Qingjuan Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The changes in miR-130b levels in human serum and the correlation with the severity of diabetic nephropathy

(2015) Chuan Lv et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Silencing of miR-195 reduces diabetic cardiomyopathy in C57BL/6 mice

(2015) Dong Zheng et al.   DIABETOLOGIA

The MicroRNAs in the Pathogenesis of Metabolic Memory

(2015) Xueyu Zhong et al.   ENDOCRINOLOGY

MicroRNA profiling unveils hyperglycaemic memory in the diabetic heart

(2015) Sarah Costantino et al.   EUROPEAN HEART JOURNAL

Human aqueous humor exosomes

(2015) W. Michael Dismuke et al.   EXPERIMENTAL EYE RESEARCH

MiR-26b modulates insulin sensitivity in adipocytes by interrupting the PTEN/PI3K/AKT pathway

(2015) G Xu et al.   INTERNATIONAL JOURNAL OF OBESITY

MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids

(2015) Xianghui Fu et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators

(2015) Ulrike Flierl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of Circulating miR-101, miR-375 and miR-802 as Biomarkers for Type 2 Diabetes

(2015) Chigusa Higuchi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

miRNAs in atherosclerotic plaque initiation, progression, and rupture

(2015) Ioannis Andreou et al.   TRENDS IN MOLECULAR MEDICINE

miRNA-103: Molecular link between insulin resistance and nonalcoholic fatty liver disease

(2015) Qian Xu   WORLD JOURNAL OF GASTROENTEROLOGY

MicroRNA-21 Regulates PI3K/Akt/mTOR Signaling by Targeting TGFβI during Skeletal Muscle Development in Pigs

(2015) Lijing Bai et al.   PLoS One

Common polymorphisms in MIR146a, MIR128a and MIR27a genes contribute to neuropathy susceptibility in type 2 diabetes

(2014) Cinzia Ciccacci et al.   ACTA DIABETOLOGICA

miR-92a inhibits vascular smooth muscle cell apoptosis: role of the MKK4–JNK pathway

(2014) Lan Zhang et al.   APOPTOSIS

MicroRNA-24 Regulates Macrophage Behavior and Retards Atherosclerosis

(2014) Karina Di Gregoli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MiRNA-145 is involved in the development of resistin-induced insulin resistance in HepG2 cells

(2014) Fengyun Wen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inherent lipid metabolic dysfunction in glycogen storage disease IIIa

(2014) Xin-Hua Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nonalcoholic fatty liver disease: A main driver of insulin resistance or a dangerous liaison?

(2014) Nanda Gruben et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cardiovascular microRNAs: as modulators and diagnostic biomarkers of diabetic heart disease

(2014) Shruti Rawal et al.   Cardiovascular Diabetology

Vitamin D manipulates miR-181c, miR-20b and miR-15a in human umbilical vein endothelial cells exposed to a diabetic-like environment

(2014) Tali Zitman-Gal et al.   Cardiovascular Diabetology

MiR-29b Protects Dorsal Root Ganglia Neurons from Diabetic Rat

(2014) Xiaona Zhang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Mineralocorticoid Receptor Blockade Improves Coronary Microvascular Function in Individuals With Type 2 Diabetes

(2014) Rajesh Garg et al.   DIABETES

Profiling of Circulating MicroRNAs Reveals Common MicroRNAs Linked to Type 2 Diabetes That Change With Insulin Sensitization

(2014) Francisco J. Ortega et al.   DIABETES CARE

MiR-135a promotes renal fibrosis in diabetic nephropathy by regulating TRPC1

(2014) Feng He et al.   DIABETOLOGIA

miR-195 regulates SIRT1-mediated changes in diabetic retinopathy

(2014) Rokhsana Mortuza et al.   DIABETOLOGIA

microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis

(2014) R. M. de Guia et al.   EMBO JOURNAL

Differential Expression of MicroRNAs in Omental Adipose Tissue From Gestational Diabetes Mellitus Subjects Reveals miR-222 as a Regulator of ERα Expression in Estrogen-Induced Insulin Resistance

(2014) Zhonghua Shi et al.   ENDOCRINOLOGY

Revisiting the metabolic syndrome and paving the way for microRNAs in non-alcoholic fatty liver disease

(2014) Duarte M. S. Ferreira et al.   FEBS Journal

Induction of miR-29a by saturated fatty acids impairs insulin signaling and glucose uptake through translational repression of IRS-1 in myocytes

(2014) Won-Mo Yang et al.   FEBS LETTERS

The Role of Circulating MicroRNA-126 (miR-126): A Novel Biomarker for Screening Prediabetes and Newly Diagnosed Type 2 Diabetes Mellitus

(2014) Yang Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Improved repair of dermal wounds in mice lacking microRNA-155

(2014) Coen van Solingen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Microvesicle-Shuttled miR-130b Reduces Fat Deposition in Recipient Primary Cultured Porcine Adipocytes by Inhibiting PPAR-γ Expression

(2014) Shifeng Pan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diabetes-Associated MicroRNAs in Pediatric Patients With Type 1 Diabetes Mellitus: A Cross-Sectional Cohort Study

(2014) Julia Osipova et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Down-regulation of miR-34a alleviates mesangial proliferation in vitro and glomerular hypertrophy in early diabetic nephropathy mice by targeting GAS1

(2014) Le Zhang et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

miRNA-1 regulates endothelin-1 in diabetes

(2014) Biao Feng et al.   LIFE SCIENCES

MicroRNA-492 reverses high glucose-induced insulin resistance in HUVEC cells through targeting resistin

(2014) Cai Ying et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The over-expression of miR-200a in the hypothalamus of ob/ob mice is linked to leptin and insulin signaling impairment

(2014) Delphine Crépin et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Up-Regulation of MicroRNA-190b Plays a Role for Decreased IGF-1 That Induces Insulin Resistance in Human Hepatocellular Carcinoma

(2014) Tzu-Min Hung et al.   PLoS One

An Agomir of miR-144-3p Accelerates Plaque Formation through Impairing Reverse Cholesterol Transport and Promoting Pro-Inflammatory Cytokine Production

(2014) Yan-Wei Hu et al.   PLoS One

Protective Effects of Let-7a and Let-7b on Oxidized Low-Density Lipoprotein Induced Endothelial Cell Injuries

(2014) Mei-hua Bao et al.   PLoS One

Targeting miR-146a to Treat Delayed Wound Healing in Human Diabetic Organ-Cultured Corneas

(2014) Michael A. Winkler et al.   PLoS One

MicroRNAs Control Macrophage Formation and Activation: The Inflammatory Link between Obesity and Cardiovascular Diseases

(2014) Richard Chang et al.   Cells

MiR-9 reduces human acyl-coenzyme A:cholesterol acyltransferase-1 to decrease THP-1 macrophage-derived foam cell formation

(2013) J. Xu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

MicroRNA miR-27b Rescues Bone Marrow–Derived Angiogenic Cell Function and Accelerates Wound Healing in Type 2 Diabetes Mellitus

(2013) Jie-Mei Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes

(2013) Robert Stöhr et al.   BIOCHEMICAL JOURNAL

miR-135a targets IRS2 and regulates insulin signaling and glucose uptake in the diabetic gastrocnemius skeletal muscle

(2013) Priyanka Agarwal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MicroRNA-26a Regulates Pathological and Physiological Angiogenesis by Targeting BMP/SMAD1 Signaling

(2013) Basak Icli et al.   CIRCULATION RESEARCH

Systemic Delivery of MicroRNA-181b Inhibits Nuclear Factor-κB Activation, Vascular Inflammation, and Atherosclerosis in Apolipoprotein E–Deficient Mice

(2013) Xinghui Sun et al.   CIRCULATION RESEARCH

Endothelial MicroRNAs and Atherosclerosis

(2013) Xinghui Sun et al.   Current Atherosclerosis Reports

MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways

(2013) Henry S. Cheng et al.   EMBO Molecular Medicine

Circulating miR-375 as a Biomarker of β-Cell Death and Diabetes in Mice

(2013) Suheda Erener et al.   ENDOCRINOLOGY

MiR-21 is Overexpressed in Response to High Glucose and Protects Endothelial Cells from Apoptosis

(2013) J. Zeng et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

MiRNA-199a-3p Regulates C2C12 Myoblast Differentiation through IGF-1/AKT/mTOR Signal Pathway

(2013) Long Jia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Exosomes in tumor microenvironment influence cancer progression and metastasis

(2013) Christoph Kahlert et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

(2013) Jan-Wilhelm Kornfeld et al.   NATURE

Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

(2013) Guanlan Xu et al.   NATURE MEDICINE

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

High Glucose Induced Alteration of SIRTs in Endothelial Cells Causes Rapid Aging in a p300 and FOXO Regulated Pathway

(2013) Rokhsana Mortuza et al.   PLoS One

MicroRNA-99 Family Targets AKT/mTOR Signaling Pathway in Dermal Wound Healing

(2013) Yi Jin et al.   PLoS One

Deep Sequencing of Small RNA Repertoires in Mice Reveals Metabolic Disorders-Associated Hepatic miRNAs

(2013) Tingming Liang et al.   PLoS One

Argonaute-3 activates the let-7a passenger strand microRNA

(2013) Julia Winter et al.   RNA Biology

Role of miR-181 family in regulating vascular inflammation and immunity

(2013) Xinghui Sun et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Body Fat Distribution and Insulin Resistance

(2013) Pavankumar Patel et al.   Nutrients

MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling

(2012) Fabiola Olivieri et al.   AGE

Downregulation of Endothelial MicroRNA-200b Supports Cutaneous Wound Angiogenesis By Desilencing GATA Binding Protein 2 and Vascular Endothelial Growth Factor Receptor 2

(2012) Yuk Cheung Chan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pro-Inflammatory Role of MicroRNA-200 in Vascular Smooth Muscle Cells From Diabetic Mice

(2012) Marpadga A. Reddy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Angiotensin-(1–7) decreases glycated albumin-induced endothelial interleukin-6 expression via modulation of miR-146a

(2012) Huang-Joe Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AngiomiR-126 expression and secretion from circulating CD34+ and CD14+ PBMCs: role for proangiogenic effects and alterations in type 2 diabetics

(2012) P. Mocharla et al.   BLOOD

Blockade of the Nuclear Factor-κB Pathway in the Endothelium Prevents Insulin Resistance and Prolongs Life Spans

(2012) Yutaka Hasegawa et al.   CIRCULATION

Association Between Coronary Vascular Dysfunction and Cardiac Mortality in Patients With and Without Diabetes Mellitus

(2012) Venkatesh L. Murthy et al.   CIRCULATION

Developing MicroRNA Therapeutics

(2012) Eva van Rooij et al.   CIRCULATION RESEARCH

MicroRNA biogenesis: regulating the regulators

(2012) Emily F. Finnegan et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

MiRNA-21 Reverses High Glucose and High Insulin Induced Insulin Resistance in 3T3-L1 Adipocytes through Targeting Phosphatase and Tensin Homologue

(2012) H.-y. Ling et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid

(2012) Yoon Mee Yang et al.   HEPATOLOGY

Essential Role of MicroRNA-155 in Regulating Endothelium-Dependent Vasorelaxation by Targeting Endothelial Nitric Oxide Synthase

(2012) Hai-Xiang Sun et al.   HYPERTENSION

Positive Surface Charge Enhances Selective Cellular Uptake and Anticancer Efficacy of Selenium Nanoparticles

(2012) Bo Yu et al.   INORGANIC CHEMISTRY

Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver

(2012) Angela M. Hall et al.   JOURNAL OF LIPID RESEARCH

Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1

(2012) S. Meng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Diabetic neuropathy: clinical manifestations and current treatments

(2012) Brian C Callaghan et al.   LANCET NEUROLOGY

The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes

(2012) Alessia Gallo et al.   PLoS One

MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A

(2011) C. Urbich et al.   BLOOD

MicroRNA-24 Regulates Vascularity After Myocardial Infarction

(2011) Jan Fiedler et al.   CIRCULATION

MicroRNA-200b Regulates Vascular Endothelial Growth Factor-Mediated Alterations in Diabetic Retinopathy

(2011) K. McArthur et al.   DIABETES

miR-146a–Mediated Extracellular Matrix Protein Production in Chronic Diabetes Complications

(2011) Biao Feng et al.   DIABETES

MicroRNA therapeutics

(2011) J A Broderick et al.   GENE THERAPY

MicroRNA-29c Is a Signature MicroRNA under High Glucose Conditions That Targets Sprouty Homolog 1, and Itsin VivoKnockdown Prevents Progression of Diabetic Nephropathy

(2011) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes

(2011) Nirmalya Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells

(2011) Guangdong Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cardiovascular Importance of the MicroRNA-23/27/24 Family

(2011) CLAUDIA BANG et al.   MICROCIRCULATION

Dicer recognizes the 5′ end of RNA for efficient and accurate processing

(2011) Jong-Eun Park et al.   NATURE

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

(2011) Sabine D. Jordan et al.   NATURE CELL BIOLOGY

MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus

(2011) Dwi Setyowati Karolina et al.   PLoS One

Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23 27 24 clusters

(2011) Q. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia

(2010) Anatoliy I. Masyuk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

Generation of somatic sensory neuron diversity and implications on sensory coding

(2010) Yang Liu et al.   CURRENT OPINION IN NEUROBIOLOGY

Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

(2010) L. M. Villeneuve et al.   DIABETES

Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription

(2010) Jason M. Aliotta et al.   EXPERIMENTAL HEMATOLOGY

Identification of MicroRNA-93 as a Novel Regulator of Vascular Endothelial Growth Factor in Hyperglycemic Conditions

(2010) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial

(2010) Frederick J Raal et al.   LANCET

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

Emerging roles of fibronectin in thrombosis

(2010) Lisa M. Maurer et al.   THROMBOSIS RESEARCH

Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes

(2010) Iain J Gallagher et al.   Genome Medicine

MicroRNA expression profiling in diabetic GK rat model

(2009) B. Huang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction

(2009) Jing Ai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Villous Trophoblasts Express and Secrete Placenta-Specific MicroRNAs into Maternal Circulation via Exosomes1

(2009) Shan-Shun Luo et al.   BIOLOGY OF REPRODUCTION

Posttranscriptional Crossregulation between Drosha and DGCR8

(2009) Jinju Han et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Effect of surface charge of magnetite nanoparticles on their internalization into breast cancer and umbilical vein endothelial cells

(2009) Tetsuya Osaka et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Hypothesis: the “metabolic memory”, the new challenge of diabetes

(2009) Antonio Ceriello   DIABETES RESEARCH AND CLINICAL PRACTICE

The deep evolution of metazoan microRNAs

(2009) Benjamin M. Wheeler et al.   EVOLUTION & DEVELOPMENT

MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2

(2009) J. Hou et al.   JOURNAL OF IMMUNOLOGY

Human aortic smooth muscle cells are insulin resistant at the receptor level but sensitive to IGF1 and IGF2

(2009) S I Chisalita et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

The Pathologic Continuum of Diabetic Vascular Disease

(2009) Gabriela Orasanu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Genome-wide identification of targets of the drosha-pasha/DGCR8 complex

(2009) S. Kadener et al.   RNA

MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

(2009) A. Bonauer et al.   SCIENCE

MicroRNA-320 EXPRESSION IN MYOCARDIAL MICROVASCULAR ENDOTHELIAL CELLS AND ITS RELATIONSHIP WITH INSULIN-LIKE GROWTH FACTOR-1 IN TYPE 2 DIABETIC RATS

(2008) XH Wang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

(2008) Shusheng Wang et al.   DEVELOPMENTAL CELL

The “Metabolic Memory”: Is More Than Just Tight Glucose Control Necessary to Prevent Diabetic Complications?

(2008) Antonio Ceriello et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Stable knockdown of microRNA in vivo by lentiviral vectors

(2008) Bernhard Gentner et al.   NATURE METHODS

The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution

(2008) Katsutomo Okamura et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

(2008) Rury R. Holman et al.   NEW ENGLAND JOURNAL OF MEDICINE

The pathogenesis of diabetic nephropathy

(2008) Suma Dronavalli et al.   Nature clinical practice. Endocrinology & metabolism