MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes

AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity

(2011) Sarat Chandarlapaty et al.   CANCER CELL

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

Simvastatin induces derepression of PTEN expression via NFκB to inhibit breast cancer cell growth

(2010) Nayana Ghosh-Choudhury et al.   CELLULAR SIGNALLING

E-Cadherin Expression Is Regulated by miR-192/215 by a Mechanism That Is Independent of the Profibrotic Effects of Transforming Growth Factor- 

(2010) B. Wang et al.   DIABETES

Identification of MicroRNA-93 as a Novel Regulator of Vascular Endothelial Growth Factor in Hyperglycemic Conditions

(2010) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of miR-216a, Mediates TGF-β-induced Collagen Expression in Kidney Cells

(2010) Mitsuo Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes

(2010) Assaad A. Eid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy

(2010) Nirmalya Dey et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeted Deletion of Dicer from Proximal Tubules Protects against Renal Ischemia-Reperfusion Injury

(2010) Q. Wei et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

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(2010) Kirti Bhatt et al.   MOLECULAR MEDICINE

mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

(2010) R. J. O. Dowling et al.   SCIENCE

Intrarenal Expression of miRNAs in Patients With Hypertensive Nephrosclerosis

(2009) G. Wang et al.   AMERICAN JOURNAL OF HYPERTENSION

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

MicroRNAs and Their Role in Progressive Kidney Diseases

(2009) M. Kato et al.   Clinical Journal of the American Society of Nephrology

Evolution under canalization and the dual roles of microRNAs--A hypothesis

(2009) C.-I Wu et al.   GENOME RESEARCH

TSC2 Deficiency Increases PTEN via HIF1α

(2009) Lenin Mahimainathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrarenal expression of microRNAs in patients with IgA nephropathy

(2009) Gang Wang et al.   LABORATORY INVESTIGATION

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

(2009) Mitsuo Kato et al.   NATURE CELL BIOLOGY

MicroRNA MiR-17 retards tissue growth and represses fibronectin expression

(2009) Sze Wan Shan et al.   NATURE CELL BIOLOGY

The binding of PRAS40 to 14-3-3 proteins is not required for activation of mTORC1 signalling by phorbol esters/ERK

(2008) Bruno D. Fonseca et al.   BIOCHEMICAL JOURNAL

Fish oil targets PTEN to regulate NFκB for downregulation of anti-apoptotic genes in breast tumor growth

(2008) Triparna Ghosh-Choudhury et al.   BREAST CANCER RESEARCH AND TREATMENT

Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells

(2008) Shu Takakura et al.   CANCER SCIENCE

Diabetic Nephropathy: Mechanisms of Renal Disease Progression

(2008) Yashpal S. Kanwar et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

(2008) Qiang Wang et al.   FASEB JOURNAL

MicroRNA-target pairs in the rat kidney identified by microRNA microarray, proteomic, and bioinformatic analysis

(2008) Z. Tian et al.   GENOME RESEARCH

Glycogen Synthase Kinase 3β Is a Novel Regulator of High Glucose- and High Insulin-induced Extracellular Matrix Protein Synthesis in Renal Proximal Tubular Epithelial Cells

(2008) Meenalakshmi M. Mariappan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Podocyte-Specific Deletion of Dicer Alters Cytoskeletal Dynamics and Causes Glomerular Disease

(2008) S. J. Harvey et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocyte-Specific Loss of Functional MicroRNAs Leads to Rapid Glomerular and Tubular Injury

(2008) J. Ho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocyte-Selective Deletion of Dicer Induces Proteinuria and Glomerulosclerosis

(2008) S. Shi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

MicroRNAs Make Big Impression in Disease After Disease

(2008) J. Couzin   SCIENCE

Raptor-rictor axis in TGFβ-induced protein synthesis

(2007) Falguni Das et al.   CELLULAR SIGNALLING

Mitogen-Stimulated and Rapamycin-Sensitive Glucose Transporter 12 Targeting and Functional Glucose Transport in Renal Epithelial Cells

(2007) Amy L. Wilson-O’Brien et al.   ENDOCRINOLOGY