Current challenges facing the assessment of the allergenic capacity of food allergens in animal models

Comprehensive metabolomics identifies the alarmin uric acid as a critical signal for the induction of peanut allergy

(2015) J. Kong et al.   ALLERGY

Gut T cell receptor-γδ+intraepithelial lymphocytes are activated selectively by cholera toxin to break oral tolerance in mice

(2015) C. P. Frossard et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Food Allergens: Is There a Correlation between Stability to Digestion and Allergenicity?

(2015) Katrine Lindholm Bøgh et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Prebiotics, probiotics, synbiotics, and the immune system

(2015) Remo Frei et al.   CURRENT OPINION IN GASTROENTEROLOGY

Intestinal dendritic cells

(2015) Elisa Schiavi et al.   CURRENT OPINION IN GASTROENTEROLOGY

Food processing and allergenicity

(2015) Kitty C.M. Verhoeckx et al.   FOOD AND CHEMICAL TOXICOLOGY

Barrier Epithelial Cells and the Control of Type 2 Immunity

(2015) Hamida Hammad et al.   IMMUNITY

Supplementation of Mice with Specific Nondigestible Oligosaccharides during Pregnancy or Lactation Leads to Diminished Sensitization and Allergy in the Female Offspring

(2015) Astrid Hogenkamp et al.   JOURNAL OF NUTRITION

Characterization of the Immunogenicity and Allergenicity of Two Cow's Milk Hydrolysates - A Study in Brown Norway Rats

(2015) K. L. Bøgh et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Egg proteins as allergens and the effects of the food matrix and processing

(2015) S. Benedé et al.   Food & Function

Dietary ω3 fatty acid exerts anti-allergic effect through the conversion to 17,18-epoxyeicosatetraenoic acid in the gut

(2015) Jun Kunisawa et al.   Scientific Reports

EAACI Food Allergy and Anaphylaxis Guidelines. Primary prevention of food allergy

(2014) A. Muraro et al.   ALLERGY

Peanut allergens are rapidly transferred in human breast milk and can prevent sensitization in mice

(2014) H. Bernard et al.   ALLERGY

EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy

(2014) A. Muraro et al.   ALLERGY

Adjuvant effects of aluminium hydroxide-adsorbed allergens and allergoids - differencesin vivoandin vitro

(2014) B. Heydenreich et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Development and evolution of risk assessment for food allergens

(2014) René W.R. Crevel et al.   FOOD AND CHEMICAL TOXICOLOGY

Food allergy: Insights into etiology, prevention, and treatment provided by murine models

(2014) Michiko K. Oyoshi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin–basophil axis

(2014) Mario Noti et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Thymic stromal lymphopoietin–mediated epicutaneous inflammation promotes acute diarrhea and anaphylaxis

(2014) Hongwei Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Cholera toxin adjuvant promotes a balanced Th1/Th2/Th17 response independently of IL-12 and IL-17 by acting on Gsα in CD11b+ DCs

(2014) J Mattsson et al.   Mucosal Immunology

Assessment of the Sensitizing Potential of Processed Peanut Proteins in Brown Norway Rats: Roasting Does Not Enhance Allergenicity

(2014) Stine Kroghsbo et al.   PLoS One

No Adjuvant Effect of Bacillus thuringiensis-Maize on Allergic Responses in Mice

(2014) Daniela Reiner et al.   PLoS One

Acid Hydrolysis of Wheat Gluten Induces Formation of New Epitopes but Does Not Enhance Sensitizing Capacity by the Oral Route: A Study in “Gluten Free” Brown Norway Rats

(2014) Stine Kroghsbo et al.   PLoS One

Peyer’s Patches and Mesenteric Lymph Nodes Cooperatively Promote Enteropathy in a Mouse Model of Food Allergy

(2014) Haruyo Nakajima-Adachi et al.   PLoS One

Dermal Toxicity Studies

(2014) Sundeep A. Chandra et al.   TOXICOLOGIC PATHOLOGY

Exposure to High Doses of Lipopolysaccharide during Ovalbumin Sensitization Prevents the Development of Allergic Th2 Responses to a Dietary Antigen

(2014) Ikuko Torii et al.   Journal of Toxicologic Pathology

The impact of structural integrity and route of administration on the antibody specificity against three cow’s milk allergens - a study in Brown Norway rats

(2014) Jeanette Madsen et al.   Clinical and Translational Allergy

Allergic sensitization: host-immune factors

(2014) Ronald van Ree et al.   Clinical and Translational Allergy

Goat's milk allergy without cow's milk allergy: suppression of non-cross-reactive epitopes on caprine β-casein

(2013) S. Hazebrouck et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis

(2013) Lisa M. Bartnikas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Aluminum Hydroxide Influences Not Only the Extent but Also the Fine Specificity and Functional Activity of Antibody Responses to Tick-Borne Encephalitis Virus in Mice

(2013) J. Zlatkovic et al.   JOURNAL OF VIROLOGY

Clinical Manifestations of Food Allergy

(2013) Tamara T. Perry et al.   PEDIATRIC ANNALS

Immunomodulation by Bifidobacterium infantis 35624 in the Murine Lamina Propria Requires Retinoic Acid-Dependent and Independent Mechanisms

(2013) Patrycja Konieczna et al.   PLoS One

Lipids are required for the development of Brazil nut allergy: the role of mouse and human iNKT cells

(2012) L. Mirotti et al.   ALLERGY

Microbiota and dietary interactions - an update to the hygiene hypothesis?

(2012) R. Frei et al.   ALLERGY

Dietary medium-chain triglycerides promote oral allergic sensitization and orally induced anaphylaxis to peanut protein in mice

(2012) Jianing Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization

(2012) Derek K. Chu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

High fat food increases gastric residence and thus thresholds for objective symptoms in allergic patients

(2012) Alan Mackie et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Immunoglobulin-E-binding epitopes of wheat allergens in patients with food allergy to wheat and in mice experimentally sensitized to wheat proteins

(2011) S. Denery-Papini et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Bifidobacterium infantis35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells

(2011) Patrycja Konieczna et al.   GUT

Sensitization with 7S Globulins from Peanut, Hazelnut, Soy or Pea Induces IgE with Different Biological Activities Which Are Modified by Soy Tolerance

(2011) Stine Kroghsbo et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases

(2011) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergenic and immunogenic potential of cow's milk β-lactoglobulin and caseins evidenced without adjuvant in germ-free mice

(2011) Stéphanie Morin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A food matrix reduces digestion and absorption of food allergens in vivo

(2011) Veronique Schulten et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Wheat gliadins modified by deamidation are more efficient than native gliadins in inducing a Th2 response in Balb/c mice experimentally sensitized to wheat allergens

(2011) Pascal Gourbeyre et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Immunological and Metabolomic Impacts of Administration of Cry1Ab Protein and MON 810 Maize in Mouse

(2011) Karine Adel-Patient et al.   PLoS One

Contribution of Classic and Alternative Effector Pathways in Peanut-Induced Anaphylactic Responses

(2011) Joost J. Smit et al.   PLoS One

Regulation by intestinal γδ T cells during establishment of food allergic sensitization in mice

(2010) M. Bol-Schoenmakers et al.   ALLERGY

Diclofenac enhances allergic responses in a mouse peanut allergy model

(2010) M. Bol-Schoenmakers et al.   CLINICAL AND EXPERIMENTAL ALLERGY

IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling

(2010) Clinton B. Mathias et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epithelial decision makers: in search of the 'epimmunome'

(2010) Mahima Swamy et al.   NATURE IMMUNOLOGY

Montelukast treatment (cysteinyl leukotriene receptor antagonist) in a model of food allergy: modifications in lymphatic cell population from rectal mucosa

(2010) M. Vinuesa et al.   REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS

Modulation of pathogen-induced CCL20 secretion from HT-29 human intestinal epithelial cells by commensal bacteria

(2009) Shomik Sibartie et al.   BMC IMMUNOLOGY

Animal models of protein allergenicity: potential benefits, pitfalls and challenges

(2009) R. J. Dearman et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Digested Ara h 1 has sensitizing capacity in Brown Norway rats

(2009) K. L. Bøgh et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Scientific advancement of novel protein allergenicity evaluation: An overview of work from the HESI Protein Allergenicity Technical Committee (2000–2008)

(2009) Karluss Thomas et al.   FOOD AND CHEMICAL TOXICOLOGY

Household peanut consumption as a risk factor for the development of peanut allergy

(2009) Adam T. Fox et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An adjuvant-free mouse model to evaluate the allergenicity of milk whey protein

(2009) B. Gonipeta et al.   JOURNAL OF DAIRY SCIENCE

Acute allergic skin response as a new tool to evaluate the allergenicity of whey hydrolysates in a mouse model of orally induced cow’s milk allergy

(2009) Betty C. A. M. Van Esch et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Review of animal models designed to predict the potential allergenicity of novel proteins in genetically modified crops

(2009) G.S. Ladics et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Approaches to risk assessment in food allergy: Report from a workshop ‘‘developing a framework for assessing the risk from allergenic foods”

(2008) C.B. Madsen et al.   FOOD AND CHEMICAL TOXICOLOGY

Dose-dependent food allergy induction against ovalbumin under acid-suppression: A murine food allergy model

(2008) S.C. Diesner et al.   IMMUNOLOGY LETTERS

Acute Allergic Skin Reactions and Intestinal Contractility Changes in Mice Orally Sensitized against Casein or Whey

(2008) Bastiaan Schouten et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Allergic Sensitization to Bovine β-Lactoglobulin: Comparison between Germ-Free and Conventional BALB/c Mice

(2008) S. Hazebrouck et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

The role of protein digestibility and antacids on food allergy outcomes

(2008) Eva Untersmayr et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergens are distributed into few protein families and possess a restricted number of biochemical functions

(2008) Christian Radauer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Impairing oral tolerance promotes allergy and anaphylaxis: A new murine food allergy model

(2008) Kirthana Ganeshan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mast cell–expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis

(2008) Brian A. Zabel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

iPAC: An initiative to fight the burden of allergies in children

(2008) Philippe A. Eigenmann et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Commensal-Induced Regulatory T Cells Mediate Protection against Pathogen-Stimulated NF-κB Activation

(2008) Caitlin O'Mahony et al.   PLoS Pathogens

Characterization of intrinsic and extrinsic risk factors for celery allergy in immunosenescence

(2007) Eva Untersmayr et al.   MECHANISMS OF AGEING AND DEVELOPMENT