标题
Evaluation of Models of Parkinson's Disease
作者
关键词
-
出版物
Frontiers in Neuroscience
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2016-01-20
DOI
10.3389/fnins.2015.00503
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease
- (2015) Pan Chen et al. Metallomics
- Axon degeneration and PGC-1 -mediated protection in a zebrafish model of -synuclein toxicity
- (2014) K. C. O'Donnell et al. Disease Models & Mechanisms
- Long-Term Overexpression of Human Wild-Type and T240R Mutant Parkin in Rat Substantia Nigra Induces Progressive Dopaminergic Neurodegeneration
- (2014) Anne-Sophie Van Rompuy et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
- (2014) Mike A Nalls et al. NATURE GENETICS
- Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration
- (2014) Elpida Tsika et al. NEUROBIOLOGY OF DISEASE
- Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease
- (2014) Kuldip D. Dave et al. NEUROBIOLOGY OF DISEASE
- Methamphetamine-induced neurotoxicity: the road to Parkinson’s disease
- (2014) Bessy Thrash et al. Pharmacological Reports
- Defining Midbrain Dopaminergic Neuron Diversity by Single-Cell Gene Expression Profiling
- (2014) Jean-Francois Poulin et al. Cell Reports
- α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson’s disease and multiple system atrophy?
- (2013) Aoife P. Kiely et al. ACTA NEUROPATHOLOGICA
- Levodopa gains psychostimulant-like properties after nigral dopaminergic loss
- (2013) Michel Engeln et al. ANNALS OF NEUROLOGY
- Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity
- (2013) Bin Liu et al. EXPERIMENTAL NEUROLOGY
- DJR-1.2 of Caenorhabditis elegans is induced by DAF-16 in the dauer state
- (2013) Ju-young Lee et al. GENE
- PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
- (2013) Michael Lazarou et al. JOURNAL OF CELL BIOLOGY
- rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration
- (2013) Marusela Oliveras-Salvá et al. Molecular Neurodegeneration
- Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
- (2013) Silke Appel-Cresswell et al. MOVEMENT DISORDERS
- A zebrafish model of PINK1 deficiency reveals key pathway dysfunction including HIF signaling
- (2013) M. Priyadarshini et al. NEUROBIOLOGY OF DISEASE
- A novel -synuclein missense mutation in Parkinson disease
- (2013) C. Proukakis et al. NEUROLOGY
- Counteraction by Nitric Oxide Synthase Inhibitor of Neurochemical Alterations of Dopaminergic System in 6-OHDA-Lesioned Rats Under l-DOPA Treatment
- (2013) Elaine Del-Bel et al. NEUROTOXICITY RESEARCH
- Parkinsonism Due to Mutations in PINK1, Parkin, and DJ-1 and Oxidative Stress and Mitochondrial Pathways
- (2013) M. R. Cookson Cold Spring Harbor Perspectives in Medicine
- (G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD
- (2012) C-Y Chen et al. CELL DEATH AND DIFFERENTIATION
- Drosophila melanogaster in the Study of Human Neurodegeneration
- (2012) Frank Hirth CNS & Neurological Disorders-Drug Targets
- Inactivation ofPink1Genein VivoSensitizes Dopamine-producing Neurons to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and Can Be Rescued by Autosomal Recessive Parkinson Disease Genes,ParkinorDJ-1
- (2012) M. Emdadul Haque et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mimicking Phosphorylation at Serine 87 Inhibits the Aggregation of Human -Synuclein and Protects against Its Toxicity in a Rat Model of Parkinson's Disease
- (2012) A. Oueslati et al. JOURNAL OF NEUROSCIENCE
- Conditional Expression of Parkinson's Disease-Related Mutant -Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription Factor Nuclear Receptor Related 1
- (2012) X. Lin et al. JOURNAL OF NEUROSCIENCE
- LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors
- (2012) Kelly M Hinkle et al. Molecular Neurodegeneration
- The nigrostriatal system in the presymptomatic and symptomatic stages in the MPTP monkey model: A PET, histological and biochemical study
- (2012) J. Blesa et al. NEUROBIOLOGY OF DISEASE
- Overexpression of Parkin Ameliorates Dopaminergic Neurodegeneration Induced by 1- Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice
- (2012) Minjuan Bian et al. PLoS One
- Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease
- (2012) M. W. C. Rousseaux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of a Unilaterally-lesioned 6-OHDA Mouse Model of Parkinson's Disease
- (2012) Sherri L. Thiele et al. Jove-Journal of Visualized Experiments
- Hypokinesia and Reduced Dopamine Levels in Zebrafish Lacking β- and γ1-Synucleins
- (2011) Chiara Milanese et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Methamphetamine neurotoxicity decreases phasic, but not tonic, dopaminergic signaling in the rat striatum
- (2011) Christopher D. Howard et al. JOURNAL OF NEUROCHEMISTRY
- A Rat Model of Progressive Nigral Neurodegeneration Induced by the Parkinson's Disease-Associated G2019S Mutation in LRRK2
- (2011) J. Dusonchet et al. JOURNAL OF NEUROSCIENCE
- Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2
- (2011) David Ramonet et al. PLoS One
- Neuropathology in Mice Expressing Mouse Alpha-Synuclein
- (2011) Claus Rieker et al. PLoS One
- Low Concentrations of Methamphetamine Can Protect Dopaminergic Cells against a Larger Oxidative Stress Injury: Mechanistic Study
- (2011) Amina El Ayadi et al. PLoS One
- Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1
- (2010) Frits Kamp et al. EMBO JOURNAL
- Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease
- (2010) James B Koprich et al. Molecular Neurodegeneration
- Progression of dopaminergic depletion in a model of MPTP-induced Parkinsonism in non-human primates. An 18F-DOPA and 11C-DTBZ PET study
- (2010) Javier Blesa et al. NEUROBIOLOGY OF DISEASE
- Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
- (2010) H.L. Melrose et al. NEUROBIOLOGY OF DISEASE
- Parkin Is Protective against Proteotoxic Stress in a Transgenic Zebrafish Model
- (2010) Mareike E. Fett et al. PLoS One
- Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of -synuclein, and apoptotic cell death in aged mice
- (2010) Y. Tong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of the WD40 Domain of LRRK2 in Zebrafish Causes Parkinsonism-Like Loss of Neurons and Locomotive Defect
- (2010) Donglai Sheng et al. PLoS Genetics
- Murine Model for Parkinson's Disease: from 6-OH Dopamine Lesion to Behavioral Test
- (2010) Fabio S.L. da Conceição et al. Jove-Journal of Visualized Experiments
- Mitochondrial dysfunction in Parkinson's disease
- (2009) Konstanze F. Winklhofer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio)
- (2009) L. Flinn et al. BRAIN
- LRRK2 in Parkinson’s disease: biochemical functions
- (2009) Vasanti S. Anand et al. FEBS Journal
- Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease
- (2009) K. Venderova et al. HUMAN MOLECULAR GENETICS
- Caenorhabditits elegansLRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth
- (2009) Julia Sämann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice
- (2009) Tohru Kitada et al. JOURNAL OF NEUROCHEMISTRY
- α-Synuclein S129 Phosphorylation Mutants Do Not Alter Nigrostriatal Toxicity in a Rat Model of Parkinson Disease
- (2009) Nikolaus R. McFarland et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Parkin Protects against LRRK2 G2019S Mutant-Induced Dopaminergic Neurodegeneration in Drosophila
- (2009) C.-H. Ng et al. JOURNAL OF NEUROSCIENCE
- Bacterial Artificial Chromosome Transgenic Mice Expressing a Truncated Mutant Parkin Exhibit Age-Dependent Hypokinetic Motor Deficits, Dopaminergic Neuron Degeneration, and Accumulation of Proteinase K-Resistant -Synuclein
- (2009) X.-H. Lu et al. JOURNAL OF NEUROSCIENCE
- Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms
- (2009) Maria C Rodriguez-Oroz et al. LANCET NEUROLOGY
- Conditional transgenic mice expressing C-terminally truncated human α-synuclein (αSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons
- (2009) João Daher et al. Molecular Neurodegeneration
- Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
- (2009) Yanping Li et al. NATURE NEUROSCIENCE
- Stereotaxical Infusion of Rotenone: A Reliable Rodent Model for Parkinson's Disease
- (2009) Nian Xiong et al. PLoS One
- R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice
- (2009) Y. Tong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Persistent MDMA-induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice
- (2008) Noelia Granado et al. JOURNAL OF NEUROCHEMISTRY
- Neurodegeneration and Motor Dysfunction in a Conditional Model of Parkinson's Disease
- (2008) S. Nuber et al. JOURNAL OF NEUROSCIENCE
- Loss of PINK1 Function Affects Development and Results in Neurodegeneration in Zebrafish
- (2008) O. Anichtchik et al. JOURNAL OF NEUROSCIENCE
- The 6-hydroxydopamine model: News from the past
- (2008) Fabio Blandini et al. PARKINSONISM & RELATED DISORDERS
- A Drosophila model for LRRK2-linked parkinsonism
- (2008) Z. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function
- (2007) Jayanth S. Chandran et al. NEUROBIOLOGY OF DISEASE
- Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein in mice
- (2006) Masaki Wakamatsu et al. NEUROBIOLOGY OF AGING
- In Vivo Labeling of Mitochondrial Complex I (NADH:UbiquinoneOxidoreductase) in Rat Brain Using [3H]Dihydrorotenone
- (2003) Deepa J. Talpade et al. JOURNAL OF NEUROCHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search