Long-Term Overexpression of Human Wild-Type and T240R Mutant Parkin in Rat Substantia Nigra Induces Progressive Dopaminergic Neurodegeneration

Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity

(2013) Bin Liu et al.   EXPERIMENTAL NEUROLOGY

Mitochondrial quality control turns out to be the principal suspect in parkin and PINK1-related autosomal recessive Parkinson's disease

(2012) Olga Corti et al.   CURRENT OPINION IN NEUROBIOLOGY

Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9

(2011) A Van der Perren et al.   GENE THERAPY

Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy

(2011) Vinay Choubey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

(2011) Fanjun Meng et al.   Molecular Neurodegeneration

Progressive Neurodegeneration or Endogenous Compensation in an Animal Model of Parkinson's Disease Produced by Decreasing Doses of Alpha-Synuclein

(2011) James B. Koprich et al.   PLoS One

Parkin Directly Modulates 26S Proteasome Activity

(2010) J. W. Um et al.   JOURNAL OF NEUROSCIENCE

Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model

(2010) Preeti J Khandelwal et al.   Molecular Neurodegeneration

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

A comprehensive analysis of deletions, multiplications, and copy number variations in PARK2

(2010) D. M. Kay et al.   NEUROLOGY

Mitophagy: the latest problem for Parkinson's disease

(2010) Cristofol Vives-Bauza et al.   TRENDS IN MOLECULAR MEDICINE

Mendelian forms of Parkinson's disease

(2009) Thomas Gasser   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Bacterial Artificial Chromosome Transgenic Mice Expressing a Truncated Mutant Parkin Exhibit Age-Dependent Hypokinetic Motor Deficits, Dopaminergic Neuron Degeneration, and Accumulation of Proteinase K-Resistant  -Synuclein

(2009) X.-H. Lu et al.   JOURNAL OF NEUROSCIENCE

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

Parkin Deficiency Delays Motor Decline and Disease Manifestation in a Mouse Model of Synucleinopathy

(2009) Margot Fournier et al.   PLoS One