Endochondral Growth Defect and Deployment of Transient Chondrocyte Behaviors Underlie Osteoarthritis Onset in a Natural Murine Model

Plasma and synovial fluid sclerostin are inversely associated with radiographic severity of knee osteoarthritis

(2014) Thomas Mabey et al.   CLINICAL BIOCHEMISTRY

Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice

(2014) Jingming Zhou et al.   ARTHRITIS RESEARCH & THERAPY

Transcriptomics of Wild-Type Mice and Mice Lacking ADAMTS-5 Activity Identifies Genes Involved in Osteoarthritis Initiation and Cartilage Destruction

(2013) John F. Bateman et al.   ARTHRITIS AND RHEUMATISM

Cartilage to bone transitions in health and disease

(2013) K A Staines et al.   JOURNAL OF ENDOCRINOLOGY

Early decrease of serum biomarkers of type II collagen degradation (Coll2-1) and joint inflammation (Coll2-1 NO2) by hyaluronic acid intra-articular injections in patients with knee osteoarthritis: A research study part of the Biovisco study

(2013) Y. Henrotin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Post-traumatic osteoarthritis: from mouse models to clinical trials

(2013) Christopher B. Little et al.   Nature Reviews Rheumatology

Spontaneous osteoarthritis in Str/ort mice is unlikely due to greater vulnerability to mechanical trauma

(2013) B. Poulet et al.   OSTEOARTHRITIS AND CARTILAGE

Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis

(2012) Blandine Poulet et al.   ARTHRITIS AND RHEUMATISM

Sclerostin is expressed in articular cartilage but loss or inhibition does not affect cartilage remodeling during aging or following mechanical injury

(2012) Martine Roudier et al.   ARTHRITIS AND RHEUMATISM

Emerging Frontiers in cartilage and chondrocyte biology

(2012) Amanda J. Fosang et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

MEPE is a novel regulator of growth plate cartilage mineralization

(2012) K.A. Staines et al.   BONE

Cartilage development and degeneration: a Wnt Wnt situation

(2012) Katherine Ann Staines et al.   CELL BIOCHEMISTRY AND FUNCTION

Differential Age-Related Bone Architecture Changes between Female and Male STR/Ort Mice

(2012) Kentaro Uchida et al.   EXPERIMENTAL ANIMALS

Reduced expression of Sfrp1 during chondrogenesis and in articular chondrocytes correlates with osteoarthritis in STR/ort mice

(2012) Juliane Pasold et al.   EXPERIMENTAL CELL RESEARCH

The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling

(2012) Katherine A Staines et al.   JOURNAL OF ENDOCRINOLOGY

Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage

(2012) F. Wei et al.   OSTEOARTHRITIS AND CARTILAGE

Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism

(2011) Gerald J Atkins et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Simultaneously Typing Nine Serotypes of Enteroviruses Associated with Hand, Foot, and Mouth Disease by a GeXP Analyzer-Based Multiplex Reverse Transcription-PCR Assay

(2011) X. Hu et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification

(2011) E J Mackie et al.   JOURNAL OF ENDOCRINOLOGY

Identification of a quantitative trait locus for spontaneous osteoarthritis in STR/ort mice

(2011) Ken Watanabe et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance

(2011) Lin Xie et al.   LIVER TRANSPLANTATION

Cartilage biology in osteoarthritis—lessons from developmental biology

(2011) Andrew A. Pitsillides et al.   Nature Reviews Rheumatology

Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis

(2011) B.Y. Chan et al.   OSTEOARTHRITIS AND CARTILAGE

Coherent imaging at the Diamond beamline I13

(2011) Christoph Rau et al.   PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE

Improved tomographic reconstructions using adaptive time-dependent intensity normalization

(2010) Valeriy Titarenko et al.   JOURNAL OF SYNCHROTRON RADIATION

Quantitation of Microcomputed Tomography-Imaged Ocular Microvasculature

(2010) ROBERT C. ATWOOD et al.   MICROCIRCULATION

Calcification of articular cartilage in human osteoarthritis

(2009) M. Fuerst et al.   ARTHRITIS AND RHEUMATISM

Osteoarthritic Changes of the Patellofemoral Joint in STR/OrtCrlj Mice Are the Earliest Detectable Changes and may be Caused by Internal Tibial Torsion

(2009) Kouji Naruse et al.   CONNECTIVE TISSUE RESEARCH

Growth plate mechanics and mechanobiology. A survey of present understanding

(2009) Isabelle Villemure et al.   JOURNAL OF BIOMECHANICS

Wnt/β-catenin Signaling Regulates Cranial Base Development and Growth

(2009) M. Nagayama et al.   JOURNAL OF DENTAL RESEARCH

Comparison of two canine registry databases on the prevalence of hip dysplasia by breed and the relationship of dysplasia with body weight and height

(2008) Frank H. Comhaire et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy

(2008) C J Brew et al.   ANNALS OF THE RHEUMATIC DISEASES

A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis

(2008) Eiki Koyama et al.   DEVELOPMENTAL BIOLOGY

MEPE-ASARM Peptides Control Extracellular Matrix Mineralization by Binding to Hydroxyapatite: An Inhibition Regulated by PHEX Cleavage of ASARM

(2008) William N Addison et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Degradation of MEPE, DMP1, and Release of SIBLING ASARM-Peptides (Minhibins): ASARM-Peptide(s) Are Directly Responsible for Defective Mineralization in HYP

(2007) Aline Martin et al.   ENDOCRINOLOGY

Endochondral ossification: How cartilage is converted into bone in the developing skeleton

(2007) E.J. Mackie et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The genetics of osteoarthritis in STR/ort mice

(2007) K. Jaeger et al.   OSTEOARTHRITIS AND CARTILAGE