Transcriptomics of Wild-Type Mice and Mice Lacking ADAMTS-5 Activity Identifies Genes Involved in Osteoarthritis Initiation and Cartilage Destruction

Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis

(2012) Blandine Poulet et al.   ARTHRITIS AND RHEUMATISM

Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo

(2012) Annika Burleigh et al.   ARTHRITIS AND RHEUMATISM

Regulation and physiological roles of the calpain system in muscular disorders

(2012) H. Sorimachi et al.   CARDIOVASCULAR RESEARCH

Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis

(2012) Mary B. Goldring   Therapeutic Advances in Musculoskeletal Disease

Angiogenesis-Associated Crosstalk Between Collagens, CXC Chemokines, and Thrombospondin Domain-Containing Proteins

(2011) Corban G. Rivera et al.   ANNALS OF BIOMEDICAL ENGINEERING

Transcriptome analysis reveals specific changes in osteoarthritis synovial fibroblasts

(2011) Manuel J Del Rey et al.   ANNALS OF THE RHEUMATIC DISEASES

Genome-wide and species-wide dissection of the genetics of arthritis severity in heterogeneous stock mice

(2011) Alyssa K. Johnsen et al.   ARTHRITIS AND RHEUMATISM

Osteoarthritic change is delayed in a Ctsk-knockout mouse model of osteoarthritis

(2011) Eiji Kozawa et al.   ARTHRITIS AND RHEUMATISM

Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice

(2011) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Proteases involved in cartilage matrix degradation in osteoarthritis

(2011) Linda Troeberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Physiology and pathophysiology of nitrosative and oxidative stress in osteoarthritic joint destruction

(2011) Christoph Ziskoven et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage

(2011) Koji Takada et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

The Role of Alpha-Dystrobrevin in Striated Muscle

(2011) Masayuki Nakamori et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cartilage Intermediate Layer Protein 2 (CILP-2) Is Expressed in Articular and Meniscal Cartilage and Down-regulated in Experimental Osteoarthritis

(2011) Bianca C. Bernardo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NDRG2 Ameliorates Hepatic Fibrosis by Inhibiting the TGF-β1/Smad Pathway and Altering the MMP2/TIMP2 Ratio in Rats

(2011) Jiandong Yang et al.   PLoS One

Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis

(2011) Rhian S Thomas et al.   ARTHRITIS RESEARCH & THERAPY

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

(2010) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

Calpain is involved in C-terminal truncation of human aggrecan

(2010) André Struglics et al.   BIOCHEMICAL JOURNAL

Analysis of meniscal degeneration and meniscal gene expression

(2010) Yubo Sun et al.   BMC MUSCULOSKELETAL DISORDERS

Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilage

(2010) T. Wei et al.   OSTEOARTHRITIS AND CARTILAGE

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis

(2010) C. Karlsson et al.   OSTEOARTHRITIS AND CARTILAGE

Genome-Wide Analyses of Gene Expression during Mouse Endochondral Ossification

(2010) Claudine G. James et al.   PLoS One

Matrix metalloproteinase 13–deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development

(2009) C. B. Little et al.   ARTHRITIS AND RHEUMATISM

Global comparative transcriptome analysis of cartilage formation in vivo

(2009) Trevor L Cameron et al.   BMC DEVELOPMENTAL BIOLOGY

Cytokine Receptor-Like Factor 1 is Highly Expressed in Damaged Human Knee Osteoarthritic Cartilage and Involved in Osteoarthritis Downstream of TGF-β

(2009) Katsuki Tsuritani et al.   CALCIFIED TISSUE INTERNATIONAL

Rnd3 Regulation of the Actin Cytoskeleton Promotes Melanoma Migration and Invasive Outgrowth in Three Dimensions

(2009) R. M. Klein et al.   CANCER RESEARCH

Identification of differentially expressed genes in trabecular bone from the iliac crest of osteoarthritic patients

(2009) E. Sánchez-Sabaté et al.   OSTEOARTHRITIS AND CARTILAGE

Degradome expression profiling in human articular cartilage

(2009) Tracey E Swingler et al.   ARTHRITIS RESEARCH & THERAPY

Genome-wide Association Scan Identifies a Prostaglandin-Endoperoxide Synthase 2 Variant Involved in Risk of Knee Osteoarthritis

(2008) Ana M. Valdes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cleavage of Type II Collagen by Cathepsin K in Human Osteoarthritic Cartilage

(2008) Valeria M. Dejica et al.   AMERICAN JOURNAL OF PATHOLOGY

Differential expression of GADD45β in normal and osteoarthritic cartilage: Potential role in homeostasis of articular chondrocytes

(2008) Kosei Ijiri et al.   ARTHRITIS AND RHEUMATISM

Zonal gene expression of chondrocytes in osteoarthritic cartilage

(2008) Naoshi Fukui et al.   ARTHRITIS AND RHEUMATISM

Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis

(2008) Francesco Dell'Accio et al.   ARTHRITIS AND RHEUMATISM

Gene expression profile of the bone microenvironment in human fragility fracture bone

(2008) B. Hopwood et al.   BONE

The Degradome database: mammalian proteases and diseases of proteolysis

(2008) V. Quesada et al.   NUCLEIC ACIDS RESEARCH

Differential transcriptome analysis of intraarticular lesional vs intact cartilage reveals new candidate genes in osteoarthritis pathophysiology

(2008) M. Geyer et al.   OSTEOARTHRITIS AND CARTILAGE

Wnt–β-catenin signaling in the pathogenesis of osteoarthritis

(2008) Maripat Corr   Nature clinical practice. Rheumatology

WATER CHANNEL ACTIVITY OF PLASMA MEMBRANE AFFECTS CHONDROCYTE MIGRATION AND ADHESION

(2007) Hai-Tao Liang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY