The microbiome-metabolome crosstalk in the pathogenesis of respiratory fungal diseases

Gut Microbiota Predict Pulmonary Infiltrates after Allogeneic Hematopoietic Cell Transplantation

(2016) Bianca Harris et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Airway Microbiota Determines Innate Cell Inflammatory or Tissue Remodeling Profiles in Lung Transplantation

(2016) Eric Bernasconi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

(2016) Gerard E. Kaiko et al.   CELL

PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognition

(2016) Cecilia Garlanda et al.   CURRENT OPINION IN IMMUNOLOGY

Lung microbiome dynamics in COPD exacerbations

(2016) Zhang Wang et al.   EUROPEAN RESPIRATORY JOURNAL

Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation

(2016) Pawan Kumar et al.   IMMUNITY

Enhancement of Microbiota in Healthy Macaques Results in Beneficial Modulation of Mucosal and Systemic Immune Function

(2016) Jennifer A. Manuzak et al.   JOURNAL OF IMMUNOLOGY

Pulmonary Th17 Antifungal Immunity Is Regulated by the Gut Microbiome

(2016) Jeremy P. McAleer et al.   JOURNAL OF IMMUNOLOGY

The Lung Microbiome, Immunity, and the Pathogenesis of Chronic Lung Disease

(2016) David N. O’Dwyer et al.   JOURNAL OF IMMUNOLOGY

Aspergillus infections in cystic fibrosis

(2016) Jill King et al.   JOURNAL OF INFECTION

A tale of two sites: how inflammation can reshape the microbiomes of the gut and lungs

(2016) Brittan S. Scales et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The evolution of cooperation within the gut microbiota

(2016) Seth Rakoff-Nahoum et al.   NATURE

The microbiome and innate immunity

(2016) Christoph A. Thaiss et al.   NATURE

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

(2016) Bruno Lamas et al.   NATURE MEDICINE

Biogeography of a human oral microbiome at the micron scale

(2016) Jessica L. Mark Welch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Volatile Compounds Emitted by Pseudomonas aeruginosa Stimulate Growth of the Fungal Pathogen Aspergillus fumigatus

(2016) Benoit Briard et al.   mBio

Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype

(2016) Leopoldo N. Segal et al.   Nature Microbiology

Metagenomic Sequencing of the Chronic Obstructive Pulmonary Disease Upper Bronchial Tract Microbiome Reveals Functional Changes Associated with Disease Severity

(2016) Simon J. S. Cameron et al.   PLoS One

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells

(2015) Koji Atarashi et al.   CELL

PTX3Polymorphisms and Invasive Mold Infections After Solid Organ Transplant: Figure 1.

(2015) Agnieszka Wójtowicz et al.   CLINICAL INFECTIOUS DISEASES

PTX3-Based Genetic Testing for Risk of Aspergillosis After Lung Transplant: Table 1.

(2015) Cristina Cunha et al.   CLINICAL INFECTIOUS DISEASES

Editorial overview: Host-microbe interactions: fungi: Heterogeneity in fungal cells, populations, and communities

(2015) Deborah A Hogan et al.   CURRENT OPINION IN MICROBIOLOGY

Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management

(2015) David W. Denning et al.   EUROPEAN RESPIRATORY JOURNAL

Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolome

(2015) Robert A Quinn et al.   ISME Journal

Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses

(2015) Darren Ruane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GPR43 – A Prototypic Metabolite Sensor Linking Metabolic and Inflammatory Diseases

(2015) Craig I. McKenzie et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Application of a Neutral Community Model To Assess Structuring of the Human Lung Microbiome

(2015) Arvind Venkataraman et al.   mBio

Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals

(2015) Christine M. Bassis et al.   mBio

Global Analysis of the Fungal Microbiome in Cystic Fibrosis Patients Reveals Loss of Function of the Transcriptional Repressor Nrg1 as a Mechanism of Pathogen Adaptation

(2015) Sang Hu Kim et al.   PLoS Pathogens

The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease

(2015) Robert P. Dickson et al.   PLoS Pathogens

Regulation of lung immunity and host defense by the intestinal microbiota

(2015) Derrick R. Samuelson et al.   Frontiers in Microbiology

The lung mycobiome: an emerging field of the human respiratory microbiome

(2015) Linh D. N. Nguyen et al.   Frontiers in Microbiology

Paving the way for predictive diagnostics and personalized treatment of invasive aspergillosis

(2015) Ana Oliveira-Coelho et al.   Frontiers in Microbiology

The Upper Respiratory Tract as a Microbial Source for Pulmonary Infections in Cystic Fibrosis. Parallels from Island Biogeography

(2014) Katrine L. Whiteson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Gut Dysbiosis Promotes M2 Macrophage Polarization and Allergic Airway Inflammation via Fungi-Induced PGE2

(2014) Yun-Gi Kim et al.   Cell Host & Microbe

A Breath Fungal Secondary Metabolite Signature to Diagnose Invasive Aspergillosis

(2014) Sophia Koo et al.   CLINICAL INFECTIOUS DISEASES

The potential impact of the pulmonary microbiome on immunopathogenesis ofAspergillus-related lung disease

(2014) Eva Kolwijck et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Innate lymphoid cells and asthma

(2014) Sanhong Yu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammation

(2014) Jian Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of the microbiome in exacerbations of chronic lung diseases

(2014) Robert P Dickson et al.   LANCET

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Lung microbiota promotes tolerance to allergens in neonates via PD-L1

(2014) Eva S Gollwitzer et al.   NATURE MEDICINE

Genetic PTX3 Deficiency and Aspergillosis in Stem-Cell Transplantation

(2014) Cristina Cunha et al.   NEW ENGLAND JOURNAL OF MEDICINE

Importance of Aspergillus spp. isolation in Acute exacerbations of severe COPD: prevalence, factors and follow-up: the FUNGI-COPD study

(2014) Arturo Huerta et al.   RESPIRATORY RESEARCH

Characterization and quantification of the fungal microbiome in serial samples from individuals with cystic fibrosis

(2014) Sven D Willger et al.   Microbiome

Th17/Treg Imbalance in Murine Cystic Fibrosis Is Linked to Indoleamine 2,3-Dioxygenase Deficiency but Corrected by Kynurenines

(2013) Rossana G. Iannitti et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of the Respiratory Microbiome in Healthy Nonsmokers and Smokers

(2013) Alison Morris et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The interplay between the innate immune system and the microbiota

(2013) Christoph A Thaiss et al.   CURRENT OPINION IN IMMUNOLOGY

Sputum microbiota in moderate versus severe patients with COPD

(2013) A. Galiana et al.   EUROPEAN RESPIRATORY JOURNAL

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Control of pathogens and pathobionts by the gut microbiota

(2013) Nobuhiko Kamada et al.   NATURE IMMUNOLOGY

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Deep Dermatophytosis and Inherited CARD9 Deficiency

(2013) Fanny Lanternier et al.   NEW ENGLAND JOURNAL OF MEDICINE

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microbiota abnormalities in inflammatory airway diseases — Potential for therapy

(2013) Eva S. Gollwitzer et al.   PHARMACOLOGY & THERAPEUTICS

A Risk Prediction Score for Invasive Mold Disease in Patients with Hematological Malignancies

(2013) Marta Stanzani et al.   PLoS One

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

Intravenous antibiotics reduce the presence ofAspergillusin adult cystic fibrosis sputum

(2013) Caroline G Baxter et al.   THORAX

The emerging world of the fungal microbiome

(2013) Gary B. Huffnagle et al.   TRENDS IN MICROBIOLOGY

IL-22 and IDO1 Affect Immunity and Tolerance to Murine and Human Vaginal Candidiasis

(2013) Antonella De Luca et al.   PLoS Pathogens

Human Genetic Susceptibility to Invasive Aspergillosis

(2013) Cristina Cunha et al.   PLoS Pathogens

Enrichment of lung microbiome with supraglottic taxa is associated with increased pulmonary inflammation

(2013) Leopoldo N Segal et al.   Microbiome

Modulation of potential respiratory pathogens by pH1N1 viral infection

(2012) R.K.-K. Leung et al.   CLINICAL MICROBIOLOGY AND INFECTION

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity

(2012) Michael C. Abt et al.   IMMUNITY

Innate Lymphoid Cell Interactions with Microbiota: Implications for Intestinal Health and Disease

(2012) Gregory F. Sonnenberg et al.   IMMUNITY

Invasive pulmonary aspergillosis is a frequent complication of critically ill H1N1 patients: a retrospective study

(2012) Joost Wauters et al.   INTENSIVE CARE MEDICINE

Beneficial effects of probiotics in upper respiratory tract infections and their mechanical actions to antagonize pathogens

(2012) M. Popova et al.   JOURNAL OF APPLIED MICROBIOLOGY

The  -Glucan Receptor Dectin-1 Promotes Lung Immunopathology during Fungal Allergy via IL-22

(2012) L. M. Lilly et al.   JOURNAL OF IMMUNOLOGY

Reciprocal interactions of the intestinal microbiota and immune system

(2012) Craig L. Maynard et al.   NATURE

Genetic variation in Toll-like receptors and disease susceptibility

(2012) Mihai G Netea et al.   NATURE IMMUNOLOGY

Dectin-1 and DC-SIGN Polymorphisms Associated with Invasive Pulmonary Aspergillosis Infection

(2012) Juan Sainz et al.   PLoS One

The Airway Microbiota in Cystic Fibrosis: A Complex Fungal and Bacterial Community—Implications for Therapeutic Management

(2012) Laurence Delhaes et al.   PLoS One

Assessing Bacterial Populations in the Lung by Replicate Analysis of Samples from the Upper and Lower Respiratory Tracts

(2012) Emily S. Charlson et al.   PLoS One

Compartmentalized Control of Skin Immunity by Resident Commensals

(2012) S. Naik et al.   SCIENCE

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

The microbiome of the lung

(2012) James M. Beck et al.   Translational Research

Asthma Prevention byLactobacillus Rhamnosusin a Mouse Model is Associated With CD4+CD25+Foxp3+T Cells

(2012) Seong-Ok Jang et al.   Allergy Asthma & Immunology Research

Pseudomonas aeruginosaPopulation Diversity and Turnover in Cystic Fibrosis Chronic Infections

(2011) Eilidh Mowat et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract

(2011) Emily S. Charlson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Nonredundant Role for Plasmacytoid Dendritic Cells in Host Defense against the Human Fungal Pathogen Aspergillus fumigatus

(2011) Zaida G. Ramirez-Ortiz et al.   Cell Host & Microbe

The Y238X Stop Codon Polymorphism in the Human β-Glucan Receptor Dectin-1 and Susceptibility to Invasive Aspergillosis

(2011) Louis Y.A. Chai et al.   JOURNAL OF INFECTIOUS DISEASES

The skin microbiome

(2011) Elizabeth A. Grice et al.   NATURE REVIEWS MICROBIOLOGY

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emerging relationship between the airway microbiota and chronic respiratory disease: clinical implications

(2011) Yvonne J Huang et al.   Expert Review of Respiratory Medicine

Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity

(2010) C. Cunha et al.   BLOOD

The Changing Microbial Epidemiology in Cystic Fibrosis

(2010) J. J. LiPuma   CLINICAL MICROBIOLOGY REVIEWS

Epidemiology of Invasive Mycoses in North America

(2010) Michael A. Pfaller et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Pseudomonas aeruginosa and their small diffusible extracellular molecules inhibit Aspergillus fumigatus biofilm formation

(2010) Eilidh Mowat et al.   FEMS MICROBIOLOGY LETTERS

PTX3 genetic variations affect the risk of Pseudomonas aeruginosa airway colonization in cystic fibrosis patients

(2010) M Chiarini et al.   GENES AND IMMUNITY

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Aspergillosis

(2009) Brahm H. Segal   NEW ENGLAND JOURNAL OF MEDICINE

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lactobacillus reuteri–induced Regulatory T cells Protect against an Allergic Airway Response in Mice

(2008) Khalil Karimi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

(2008) Shahla Abdollahi-Roodsaz et al.   JOURNAL OF CLINICAL INVESTIGATION