Selenium and Metabolic Disorders: An Emphasis on Type 2 Diabetes Risk

Glutathione peroxidase 1 Pro198Leu variant contributes to the metabolic syndrome in men in a large Japanese cohort

(2018) Masafumi Kuzuya et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Regulation of Selenium Metabolism and Transport

(2015) Raymond F. Burk et al.   Annual Review of Nutrition

Diet-Induced Obesity in the Selenocysteine Lyase Knockout Mouse

(2015) Lucia A. Seale et al.   ANTIOXIDANTS & REDOX SIGNALING

No effect of modest selenium supplementation on insulin resistance in UK pregnant women, as assessed by plasma adiponectin concentration

(2015) Jinyuan Mao et al.   BRITISH JOURNAL OF NUTRITION

Epigenetic effects of selenium and their implications for health

(2015) Bodo Speckmann et al.   Epigenetics

Competition between the Brain and Testes under Selenium-Compromised Conditions: Insight into Sex Differences in Selenium Metabolism and Risk of Neurodevelopmental Disease

(2015) M. W. Pitts et al.   JOURNAL OF NEUROSCIENCE

Selenium Cycling Across Soil-Plant-Atmosphere Interfaces: A Critical Review

(2015) Lenny Winkel et al.   Nutrients

Role of selenium in male reproduction—A review

(2014) U. Ahsan et al.   ANIMAL REPRODUCTION SCIENCE

Selenoprotein S is involved in maintenance and transport of multiprotein complexes

(2014) Anton A. Turanov et al.   BIOCHEMICAL JOURNAL

Hepatic Oxidative Stress Promotes Insulin-STAT-5 Signaling and Obesity by Inactivating Protein Tyrosine Phosphatase N2

(2014) Esteban N. Gurzov et al.   Cell Metabolism

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

(2014) Nathalie Esser et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Mice Lacking Selenoprotein P and Selenocysteine Lyase Exhibit Severe Neurological Dysfunction, Neurodegeneration, and Audiogenic Seizures

(2014) China N. Byrns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiological role and regulation of iodothyronine deiodinases: A 2011 update

(2014) A. Marsili et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

12-Lipoxygenase Promotes Obesity-Induced Oxidative Stress in Pancreatic Islets

(2014) S. A. Tersey et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of adiponectin system in insulin resistance

(2014) Chiara Caselli   MOLECULAR GENETICS AND METABOLISM

Thyroid Hormone Regulation of Metabolism

(2014) Rashmi Mullur et al.   PHYSIOLOGICAL REVIEWS

Nonsense-mediated decay factors are involved in the regulation of selenoprotein mRNA levels during selenium deficiency

(2014) Ali Seyedali et al.   RNA

High-Fat-Fed Obese Glutathione Peroxidase 1-Deficient Mice Exhibit Defective Insulin Secretion but Protection from Hepatic Steatosis and Liver Damage

(2013) Troy L. Merry et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione Peroxidase Mimic Ebselen Improves Glucose-Stimulated Insulin Secretion in Murine Islets

(2013) Xinhui Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Identification of nucleotides and amino acids that mediate the interaction between ribosomal protein L30 and the SECIS element

(2013) Abby L Bifano et al.   BMC MOLECULAR BIOLOGY

The PACAP-Regulated Gene Selenoprotein T Is Abundantly Expressed in Mouse and Human β-Cells and Its Targeted Inactivation Impairs Glucose Tolerance

(2013) Gaëtan Prevost et al.   ENDOCRINOLOGY

Epidemiology of selenium and type 2 diabetes: Can we make sense of it?

(2013) Margaret P. Rayman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics

(2013) Jacklyn N. Hellwege et al.   GENE

Diet-induced obesity mediated by the JNK/DIO2 signal transduction pathway

(2013) S. Vernia et al.   GENES & DEVELOPMENT

Selenium Inhibits LPS-Induced Pro-inflammatory Gene Expression by Modulating MAPK and NF-κB Signaling Pathways in Mouse Mammary Epithelial Cells in Primary Culture

(2013) Wen Zhang et al.   INFLAMMATION

Deletion of Selenoprotein M Leads to Obesity without Cognitive Deficits

(2013) Matthew W. Pitts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Translational Redefinition of UGA Codons Is Regulated by Selenium Availability

(2013) Michael T. Howard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin Suppresses Expression of the Selenoprotein P Gene via an AMP-activated Kinase (AMPK)/FoxO3a Pathway in H4IIEC3 Hepatocytes

(2013) Hiroaki Takayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of hypothalamic and pituitary T3 production regulates TSH expression

(2013) Tatiana L. Fonseca et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular insulin resistance disrupts hypothalamic mHypoA-POMC/GFP neuronal signaling pathways

(2013) Anaies Nazarians-Armavil et al.   JOURNAL OF ENDOCRINOLOGY

Glucose sensing mechanisms in hypothalamic cell models: Glucose inhibition of AgRP synthesis and secretion

(2013) Jennifer A. Chalmers et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

High selenium impairs hepatic insulin sensitivity through opposite regulation of ROS

(2013) Xin Wang et al.   TOXICOLOGY LETTERS

Selenoproteins and Cancer Prevention

(2012) Cindy D. Davis et al.   Annual Review of Nutrition

A Bioinformatics Approach to Characterize Mammalian Selenoprotein T

(2012) Mohamed E. Moustafa et al.   BIOCHEMICAL GENETICS

Selenium Downregulates RAGE and NFκB Expression in Diabetic Rats

(2012) Sneha S. Pillai et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

An in vitro investigation of species-dependent intestinal transport of selenium and the impact of this process on selenium bioavailability

(2012) Celine Thiry et al.   BRITISH JOURNAL OF NUTRITION

Toenail Selenium and Incidence of Type 2 Diabetes in U.S. Men and Women

(2012) K. Park et al.   DIABETES CARE

Supranutritional selenium induces alterations in molecular targets related to energy metabolism in skeletal muscle and visceral adipose tissue of pigs

(2012) Antonio Pinto et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Localization and regulation of pancreatic selenoprotein P

(2012) Holger Steinbrenner et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Selenium and human health

(2012) Margaret P Rayman   LANCET

Disruption of the Selenocysteine Lyase-Mediated Selenium Recycling Pathway Leads to Metabolic Syndrome in Mice

(2012) L. A. Seale et al.   MOLECULAR AND CELLULAR BIOLOGY

Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes

(2012) Hirofumi Misu et al.   PLoS One

A Randomized Trial of Selenium Supplementation and Risk of Type-2 Diabetes, as Assessed by Plasma Adiponectin

(2012) Margaret P. Rayman et al.   PLoS One

Both Maximal Expression of Selenoproteins and Selenoprotein Deficiency Can Promote Development of Type 2 Diabetes-Like Phenotype in Mice

(2011) Vyacheslav M. Labunskyy et al.   ANTIOXIDANTS & REDOX SIGNALING

PLP-dependent H2S biogenesis

(2011) Sangita Singh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cellular Leptin Resistance Impairs the Leptin-Mediated Suppression of Neuropeptide Y Secretion in Hypothalamic Neurons

(2011) Sandeep S. Dhillon et al.   ENDOCRINOLOGY

The PACAP-Regulated Gene Selenoprotein T Is Highly Induced in Nervous, Endocrine, and Metabolic Tissues during Ontogenetic and Regenerative Processes

(2011) Yannick Tanguy et al.   ENDOCRINOLOGY

Vitamin E and the Risk of Prostate Cancer

(2011) Eric A. Klein et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Serum Selenoprotein P Levels in Patients with Type 2 Diabetes and Prediabetes: Implications for Insulin Resistance, Inflammation, and Atherosclerosis

(2011) S. J. Yang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A Human Model of Selenium that Integrates Metabolism from Selenite and Selenomethionine

(2011) Meryl E. Wastney et al.   JOURNAL OF NUTRITION

Mammalian Selenocysteine Lyase Is Involved in Selenoprotein Biosynthesis

(2011) Suguru KUROKAWA et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Selenium, selenoproteins and the thyroid gland: interactions in health and disease

(2011) Lutz Schomburg   Nature Reviews Endocrinology

Mice with a Targeted Deletion of the Type 2 Deiodinase Are Insulin Resistant and Susceptible to Diet Induced Obesity

(2011) Alessandro Marsili et al.   PLoS One

Establishing optimal selenium status: results of a randomized, double-blind, placebo-controlled trial

(2010) Rachel Hurst et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Selenium in Human Health and Disease

(2010) Susan J. Fairweather-Tait et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenium controls the sex-specific immune response and selenoprotein expression during the acute-phase response in mice

(2010) Mette Stoedter et al.   BIOCHEMICAL JOURNAL

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

(2010) Hirofumi Misu et al.   Cell Metabolism

Reaction Mechanism and Molecular Basis for Selenium/Sulfur Discrimination of Selenocysteine Lyase

(2010) Rie Omi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway

(2010) Marcelo A Christoffolete et al.   JOURNAL OF ENDOCRINOLOGY

Expression of the selenoprotein S (SELS) gene in subcutaneous adipose tissue and SELS genotype are associated with metabolic risk factors

(2010) Maja Olsson et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Plasma selenium and risk of dysglycemia in an elderly French population: results from the prospective Epidemiology of Vascular Ageing Study

(2010) Tasnime N Akbaraly et al.   Nutrition & Metabolism

Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery

(2010) X.-M. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Neuroprotective Functions of Selenoprotein M and its Role in Cytosolic Calcium Regulation

(2009) Mariclair A. Reeves et al.   ANTIOXIDANTS & REDOX SIGNALING

Attenuation of hepatic expression and secretion of selenoprotein P by metformin

(2009) Bodo Speckmann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium

(2009) Lutz Schomburg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Identification of Proteins Interacting with Selenocysteine Lyase

(2009) Ryuta TOBE et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance

(2009) Lale Ozcan et al.   Cell Metabolism

Serum Selenium Concentrations and Diabetes in U.S. Adults: National Health and Nutrition Examination Survey (NHANES) 2003–2004

(2009) Martin Laclaustra et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Selenium and Inflammation: Underlying Anti-inflammatory Mechanisms

(2009) L. H. Duntas   HORMONE AND METABOLIC RESEARCH

Food-chain selenium and human health: emphasis on intake

(2008) Margaret P. Rayman   BRITISH JOURNAL OF NUTRITION

Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice

(2008) X. D. Wang et al.   DIABETOLOGIA

Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion

(2008) Luca Grumolato et al.   FASEB JOURNAL

Selenium stimulates pancreatic beta-cell gene expression and enhances islet function

(2008) Susan C. Campbell et al.   FEBS LETTERS

Selenoprotein P expression is controlled through interaction of the coactivator PGC-1α with FoxO1a and hepatocyte nuclear factor 4α transcription factors

(2008) Bodo Speckmann et al.   HEPATOLOGY

Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers

(2008) Scott M. Lippman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of selenium on pancreatic proinflammatory cytokines in streptozotocin-induced diabetic mice

(2008) Jinhong Zeng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY