Selenium in Human Health and Disease

Functional effects of a common single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene: interaction with sex

(2018) Catherine Méplan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Selenium bioavailability: current knowledge and future research requirements

(2010) Susan J Fairweather-Tait et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Establishing optimal selenium status: results of a randomized, double-blind, placebo-controlled trial

(2010) Rachel Hurst et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Determination of selenomethionine, selenocysteine, and inorganic selenium in eggs by HPLC–inductively coupled plasma mass spectrometry

(2010) Elżbieta Lipiec et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Acute Selenium Toxicity Associated With a Dietary Supplement

(2010) Jennifer K. MacFarquhar   ARCHIVES OF INTERNAL MEDICINE

Comparative analysis of gene expression profiles between primary knee osteoarthritis and an osteoarthritis endemic to Northwestern China, Kashin-Beck disease

(2010) Chen Duan et al.   ARTHRITIS AND RHEUMATISM

Longitudinal association between toenail selenium levels and measures of subclinical atherosclerosis: The CARDIA trace element study

(2010) Pengcheng Xun et al.   ATHEROSCLEROSIS

Antioxidant defence systems and generation of reactive oxygen species in osteosarcoma cells with defective mitochondria: Effect of selenium

(2010) Marta Wojewoda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Regulation of Redox Signaling by Selenoproteins

(2010) Wayne Chris Hawkes et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Selenium Level Surveillance for the Year 2007 of Keshan Disease in Endemic Areas and Analysis on Surveillance Results Between 2003 and 2007

(2010) Jingyuan Yang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Toenail selenium status and DNA repair capacity among female BRCA1 mutation carriers

(2010) Joanne Kotsopoulos et al.   CANCER CAUSES & CONTROL

Ingestion of selenium and other antioxidants during prostate cancer radiotherapy: A good thing?

(2010) A. Tabassum et al.   CANCER TREATMENT REVIEWS

Genetic variants in selenoprotein genes increase risk of colorectal cancer

(2010) C. Meplan et al.   CARCINOGENESIS

Selenium and glutamine supplements: where are we heading? A critical care perspective

(2010) Peter JD Andrews   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Nutri-RecQuest: a web-based search engine on current micronutrient recommendations

(2010) A E J M Cavelaars et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Multicenter, Phase 3 Trial Comparing Selenium Supplementation With Observation in Gynecologic Radiation Oncology

(2010) Ralph Muecke et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The Effect of Short Tandem Repeat Loci and Low Selenium Levels on Endemic Osteoarthritis in China

(2010) Xiao W Shi et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Selenoprotein-Related Disease in a Young Girl Caused by Nonsense Mutations in theSBP2Gene

(2010) Monalisa Ferreira Azevedo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

mRNA transcripts as molecular biomarkers in medicine and nutrition☆

(2010) Roger A. Sunde   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Plasma selenium and risk of dysglycemia in an elderly French population: results from the prospective Epidemiology of Vascular Ageing Study

(2010) Tasnime N Akbaraly et al.   Nutrition & Metabolism

Association study between polymorphisms in selenoprotein genes and susceptibility to Kashin-Beck disease

(2010) Y.M. Xiong et al.   OSTEOARTHRITIS AND CARTILAGE

Eats roots and leaves. Can edible horticultural crops address dietary calcium, magnesium and potassium deficiencies?

(2010) Martin R. Broadley et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Methods of assessment of selenium status in humans: a systematic review

(2009) Kate Ashton et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Serum Selenium and Peripheral Arterial Disease: Results From the National Health and Nutrition Examination Survey, 2003-2004

(2009) J. Bleys et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Relative Abundance of Selenoprotein P Isoforms in Human Plasma Depends on Genotype, Se Intake, and Cancer Status

(2009) Catherine Méplan et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Regulation of Cell Survival by the Thioredoxin Superfamily: An Implication of Redox Gene Therapy in the Heart

(2009) Md. Kaimul Ahsan et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenoproteins and Protection against Oxidative Stress: Selenoprotein N as a Novel Player at the Crossroads of Redox Signaling and Calcium Homeostasis

(2009) Sandrine Arbogast et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenium and the Selenoprotein Thioredoxin Reductase in the Prevention, Treatment and Diagnostics of Cancer

(2009) Markus Selenius et al.   ANTIOXIDANTS & REDOX SIGNALING

In vitro evaluation of selenium genotoxic, cytotoxic, and protective effects: a review

(2009) Vanessa Valdiglesias et al.   ARCHIVES OF TOXICOLOGY

Serum selenium and prognosis in cardiovascular disease: results from the AtheroGene study

(2009) Edith Lubos et al.   ATHEROSCLEROSIS

Selenium and thyroid

(2009) Josef Köhrle et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Regulation and function of selenoproteins in human disease

(2009) Frederick P. Bellinger et al.   BIOCHEMICAL JOURNAL

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase

(2009) Valentina Gandin et al.   BIOCHEMICAL PHARMACOLOGY

Selenoprotein function and muscle disease

(2009) Alain Lescure et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Metabolism of selenium compounds catalyzed by the mammalian selenoprotein thioredoxin reductase

(2009) Jun Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Molecular mechanisms by which selenoproteins affect cancer risk and progression

(2009) Pin Zhuo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selenoproteins and human health: Insights from epidemiological data

(2009) Margaret P. Rayman   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium

(2009) Lutz Schomburg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Protection against reactive oxygen species by selenoproteins

(2009) Holger Steinbrenner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selenoprotein P—Expression, functions, and roles in mammals

(2009) Raymond F. Burk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selenoprotein S (SEPS1) gene -105G>A promoter polymorphism influences the susceptibility to gastric cancer in the Japanese population

(2009) Tomoyuki Shibata et al.   BMC GASTROENTEROLOGY

Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression

(2009) Bradley A Carlson et al.   BMC IMMUNOLOGY

Selenium Supplementation Reduced Oxidative DNA Damage in Adnexectomized BRCA1 Mutations Carriers

(2009) T. Dziaman et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Reduced Serum Selenoprotein P Concentrations in German Prostate Cancer Patients

(2009) H.-A. Meyer et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Selenium accumulation by forage and grain crops and volatilization from seleniferous soils amended with different organic materials

(2009) K.S. Dhillon et al.   CHEMOSPHERE

Level of selenoprotein transcripts in peripheral leukocytes of patients with bladder cancer and healthy individuals

(2009) Edyta Reszka et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Selenium in human and animal nutrition: Resolved and unresolved issues. A partly historical treatise in commemoration of the fiftieth anniversary of the discovery of the biological essentiality of selenium, dedicated to the memory of Klaus Schwarz (1914–1978) on the occasion of the thirtieth anniversary of his death

(2009) Gerhard N. Schrauzer et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Producing selenium-enriched eggs and meat to improve the selenium status of the general population

(2009) Vladimir I. Fisinin et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Selenium intake and cardiovascular risk: what is new?

(2009) Ana Navas-Acien et al.   CURRENT OPINION IN LIPIDOLOGY

Defining the Roles of the Iodothyronine Deiodinases: Current Concepts and Challenges

(2009) Donald L. St. Germain et al.   ENDOCRINOLOGY

The Sodium-Iodide Symporter NIS and Pendrin in Iodide Homeostasis of the Thyroid

(2009) Aigerim Bizhanova et al.   ENDOCRINOLOGY

Increased consumption of wheat biofortified with selenium does not modify biomarkers of cancer risk, oxidative stress, or immune function in healthy Australian males

(2009) Jing Wu et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Serum Selenium Concentrations and Diabetes in U.S. Adults: National Health and Nutrition Examination Survey (NHANES) 2003–2004

(2009) Martin Laclaustra et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Selenium Characterization in the Global Rice Supply Chain

(2009) Paul N. Williams et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Association between GPx1 Pro198Leu polymorphism, GPx1 activity and plasma selenium concentration in humans

(2009) E. Jablonska et al.   EUROPEAN JOURNAL OF NUTRITION

Selenoprotein P, Rather than Glutathione Peroxidase, as a Potential Marker of Septic Shock and Related Syndromes

(2009) X. Forceville et al.   EUROPEAN SURGICAL RESEARCH

Mitochondrial glutathione peroxidase 4 disruption causes male infertility

(2009) Manuela Schneider et al.   FASEB JOURNAL

Human-specific induction of glutathione peroxidase-3 by proteasome inhibition in cardiovascular cells

(2009) Kera Westphal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selenium in Intravenous Nutrition

(2009) Alan Shenkin   GASTROENTEROLOGY

Selenium Status and the Risk of Esophageal and Gastric Cancer Subtypes: The Netherlands Cohort Study

(2009) Jessie Steevens et al.   GASTROENTEROLOGY

Selenium and Inflammation: Underlying Anti-inflammatory Mechanisms

(2009) L. H. Duntas   HORMONE AND METABOLIC RESEARCH

Lack of Glutathione Peroxidase 1 Accelerates Cardiac-Specific Hypertrophy and Dysfunction in Angiotensin II Hypertension

(2009) Noelia Ardanaz et al.   HYPERTENSION

Selenium Supplementation Does Not Affect Testicular Selenium Status or Semen Quality in North American Men

(2009) W. C. Hawkes et al.   JOURNAL OF ANDROLOGY

Depletion of Selenoprotein GPx4 in Spermatocytes Causes Male Infertility in Mice

(2009) Hirotaka Imai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma Selenium, Manganese Superoxide Dismutase, and Intermediate- or High-Risk Prostate Cancer

(2009) June M. Chan et al.   JOURNAL OF CLINICAL ONCOLOGY

Rationale and Design of the Pediatric Critical Illness Stress-Induced Immune Suppression (CRISIS) Prevention Trial

(2009) Joseph Carcillo et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Total and Cancer Mortality After Supplementation With Vitamins and Minerals: Follow-up of the Linxian General Population Nutrition Intervention Trial

(2009) Y.-L. Qiao et al.   JNCI-Journal of the National Cancer Institute

Selenium and thyroid hormone axis in critical ill states: An overview of conflicting view points

(2009) Roland Gärtner   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Efficacy of Antioxidant Supplementation in Reducing Primary Cancer Incidence and Mortality: Systematic Review and Meta-analysis

(2009) Aditya Bardia et al.   MAYO CLINIC PROCEEDINGS

Novel structural determinants in human SECIS elements modulate the translational recoding of UGA as selenocysteine

(2009) Lynda Latrèche et al.   NUCLEIC ACIDS RESEARCH

Impact of sulphur fertilisation on crop response to selenium fertilisation

(2009) J. L. Stroud et al.   PLANT AND SOIL

Soil factors affecting selenium concentration in wheat grain and the fate and speciation of Se fertilisers applied to soil

(2009) J. L. Stroud et al.   PLANT AND SOIL

Selenium biofortification of high-yielding winter wheat (Triticum aestivum L.) by liquid or granular Se fertilisation

(2009) Martin R. Broadley et al.   PLANT AND SOIL

XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors

(2009) R. Schlaberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Symposium on ‘Geographical and geological influences on nutrition’ Factors controlling the distribution of selenium in the environment and their impact on health and nutrition

(2009) Christopher C. Johnson et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

A Medical Mystery in Middle China

(2009) R. Stone   SCIENCE

Simultaneous determination of arsenic and selenium species in fish tissues using microwave-assisted enzymatic extraction and ion chromatography–inductively coupled plasma mass spectrometry

(2009) Laura Hinojosa Reyes et al.   TALANTA

Osteo-Chondroprogenitor–Specific Deletion of the Selenocysteine tRNA Gene, Trsp, Leads to Chondronecrosis and Abnormal Skeletal Development: A Putative Model for Kashin-Beck Disease

(2009) Charlene M. Downey et al.   PLoS Genetics

Selenium and asthma: a complex relationship

(2008) P. R. Hoffmann   ALLERGY

A case-control study of the relation between plasma selenium and asthma in European populations: a GA2LEN project*

(2008) P. Burney et al.   ALLERGY

Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease

(2008) Renate Schnabel et al.   AMERICAN HEART JOURNAL

Genetic association of preeclampsia to the inflammatory response gene SEPS1

(2008) Eric K. Moses et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Selenium supplementation does not improve vascular responsiveness in healthy North American men

(2008) Wayne Chris Hawkes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Determination of selenocysteine and selenomethionine in edible animal tissues by 2D size-exclusion reversed-phase HPLC-ICP MS following carbamidomethylation and proteolytic extraction

(2008) Katarzyna Bierla et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Nutrigenomics and Selenium: Gene Expression Patterns, Physiological Targets, and Genetics

(2008) John Hesketh   Annual Review of Nutrition

Serum Selenium Levels and All-Cause, Cancer, and Cardiovascular Mortality Among US Adults

(2008) Joachim Bleys   ARCHIVES OF INTERNAL MEDICINE

Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination inSepp-knockout mice

(2008) Kostja Renko et al.   BIOCHEMICAL JOURNAL

High-Dose Sodium Selenite Can Induce Apoptosis of Lymphoma Cells in Adult Patients with Non-Hodgkin’s Lymphoma

(2008) Inas A. Asfour et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Polymorphisms in the selenoprotein S gene: lack of association with autoimmune inflammatory diseases

(2008) Alfonso Martinez et al.   BMC GENOMICS

Variation in the Selenoenzyme Genes and Risk of Advanced Distal Colorectal Adenoma

(2008) U. Peters et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Se-methylselenocysteine alters collagen gene and protein expression in human prostate cells

(2008) Rachel Hurst et al.   CANCER LETTERS

Interaction between Single Nucleotide Polymorphisms in Selenoprotein P and Mitochondrial Superoxide Dismutase Determines Prostate Cancer Risk

(2008) M. L. Cooper et al.   CANCER RESEARCH

Characteristics of transport of selenoamino acids by epithelial amino acid transporters

(2008) A. Nickel et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Interaction of glutathione peroxidase-1 and selenium in endemic dilated cardiomyopathy

(2008) Cong Lei et al.   CLINICA CHIMICA ACTA

Selenium and anticarcinogenesis: underlying mechanisms

(2008) Matthew I Jackson et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice

(2008) X. D. Wang et al.   DIABETOLOGIA

Minimising the population risk of micronutrient deficiency and over-consumption: a new approach using selenium as an example

(2008) Andrew G. Renwick et al.   EUROPEAN JOURNAL OF NUTRITION

Lung cancer risk associated with selenium status is modified in smoking individuals by Sep15 polymorphism

(2008) Ewa Jablonska et al.   EUROPEAN JOURNAL OF NUTRITION

Synergy between broccoli sprout extract and selenium in the upregulation of thioredoxin reductase in human hepatocytes

(2008) Dan Li et al.   FOOD CHEMISTRY

Serum selenium and glutathione peroxidase-3 activity: biomarkers of systemic inflammation in the critically ill?

(2008) William Manzanares et al.   INTENSIVE CARE MEDICINE

Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers

(2008) Scott M. Lippman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of dietary supplementation with selenium-enriched yeast or sodium selenite on selenium tissue distribution and meat quality in beef cattle1

(2008) D. T. Juniper et al.   JOURNAL OF ANIMAL SCIENCE

Thioredoxin Reductase-1 Negatively Regulates HIV-1 Transactivating Protein Tat-dependent Transcription in Human Macrophages

(2008) Parisa Kalantari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MsrB1(Methionine-R-sulfoxide Reductase 1) Knock-out Mice

(2008) Dmitri E. Fomenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Megalin Mediates Selenoprotein P Uptake by Kidney Proximal Tubule Epithelial Cells

(2008) Gary E. Olson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenoproteins

(2008) Jun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenoproteins Mediate T Cell Immunity through an Antioxidant Mechanism

(2008) Rajeev K. Shrimali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detection of serum proteomic changes and discovery of serum biomarkers for Kashin-Beck disease using surface-enhanced laser desorption ionization mass spectrometry (SELDI-TOF MS)

(2008) Shuang Wang et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Trace Element Loss in Urine and Effluent Following Traumatic Injury

(2008) Catherine J. Klein et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Effect of different selenium sources and levels on porcine circovirus type 2 replication in vitro

(2008) Qunxing Pan et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Efficacy of Selenium and/or N-Acetyl-Cysteine for Improving Semen Parameters in Infertile Men: A Double-Blind, Placebo Controlled, Randomized Study

(2008) Mohammad Reza Safarinejad et al.   JOURNAL OF UROLOGY

Promotion of the articular cartilage proteoglycan degradation by T-2 toxin and selenium protective effect

(2008) Si-yuan Li et al.   Journal of Zhejiang University-SCIENCE B

On the importance of selenium and iodine metabolism for thyroid hormone biosynthesis and human health

(2008) Lutz Schomburg et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Selenium attenuates pro-inflammatory gene expression in macrophages

(2008) Hema Vunta et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The influence of selenium on immune responses

(2008) Peter R. Hoffmann et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Nutritional Prevention of Cancer: 400 Mcg Per Day Selenium Treatment

(2008) Mary Reid et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis

(2008) W.Z. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

Selenium for preventing Kashin-Beck osteoarthropathy in children: a meta-analysis

(2008) K. Zou et al.   OSTEOARTHRITIS AND CARTILAGE

Articular cartilage metabolism in patients with Kashin–Beck Disease: an endemic osteoarthropathy in China

(2007) J. Cao et al.   OSTEOARTHRITIS AND CARTILAGE

Historical changes in the concentrations of selenium in soil and wheat grain from the Broadbalk experiment over the last 160 years

(2007) Ming-Sheng Fan et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Methylation and demethylation of intermediates selenide and methylselenol in the metabolism of selenium

(2007) Yuki Ohta et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Selenium content of Finnish oats in 1997-1999: effect of cultivars and cultivation techniques

(2005) M. EUROLA et al.   AGRICULTURAL AND FOOD SCIENCE