Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis

DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression

(2016) M. Borghesan et al.   CANCER RESEARCH

Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma

(2016) Simone Jueliger et al.   Epigenetics

Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leukocytosis and fear response in mice

(2016) Giulia Bolasco et al.   Aging-US

SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation

(2016) Valerio Pazienza et al.   Aging-US

MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory Phenotype

(2015) Hongshan Chen et al.   MOLECULAR CELL

Moderate calorie restriction to achieve normal weight reverses β-cell dysfunction in diet-induced obese mice: involvement of autophagy

(2015) Xiuying Gao et al.   Nutrition & Metabolism

Histone Variants and Epigenetics

(2015) Steven Henikoff et al.   Cold Spring Harbor Perspectives in Biology

Decellularized human liver as a natural 3D-scaffold for liver bioengineering and transplantation

(2015) Giuseppe Mazza et al.   Scientific Reports

Regulation of Adipogenesis and Key Adipogenic Gene Expression by 1, 25-Dihydroxyvitamin D in 3T3-L1 Cells

(2015) Shuhan Ji et al.   PLoS One

Histone variants and lipid metabolism

(2014) Michela Borghesan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

ChIPseek, a web-based analysis tool for ChIP data

(2014) Ting-Wen Chen et al.   BMC GENOMICS

Genetic ablation of macrohistone H2A1 leads to increased leanness, glucose tolerance and energy expenditure in mice fed a high-fat diet

(2014) F Sheedfar et al.   INTERNATIONAL JOURNAL OF OBESITY

DNA methylation and body-mass index: a genome-wide analysis

(2014) Katherine J Dick et al.   LANCET

Single-nucleotide polymorphisms and DNA methylation markers associated with central obesity and regulation of body weight

(2014) Leticia Goni et al.   NUTRITION REVIEWS

Non-Alcoholic Fatty Pancreas Disease Pathogenesis: A Role for Developmental Programming and Altered Circadian Rhythms

(2014) Rebeca Carter et al.   PLoS One

Epigenetics in Adipose Tissue, Obesity, Weight Loss, and Diabetes

(2014) J. Alfredo Martínez et al.   Advances in Nutrition

MacroH2A – An epigenetic regulator of cancer

(2013) Neus Cantariño et al.   CANCER LETTERS

p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity

(2013) A Molchadsky et al.   CELL DEATH AND DIFFERENTIATION

Redox Homeostasis and Epigenetics in Non-alcoholic Fatty Liver Disease (NAFLD)

(2013) Christine Podrini et al.   CURRENT PHARMACEUTICAL DESIGN

Histone variants in pluripotency and disease

(2013) P. J. Skene et al.   DEVELOPMENT

Visualization of inactive X chromosome in preimplantation embryos utilizing MacroH2A-EGFP transgenic mouse

(2013) Atsumi Soma et al.   GENESIS

Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma

(2013) Francesca Rappa et al.   PLoS One

MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency

(2013) Alexandre Gaspar-Maia et al.   Nature Communications

Macrohistone Variants Preserve Cell Identity by Preventing the Gain of H3K4me2 during Reprogramming to Pluripotency

(2013) María J. Barrero et al.   Cell Reports

Differential Regulation and Predictive Potential of MacroH2A1 Isoforms in Colon Cancer

(2012) Judith C. Sporn et al.   AMERICAN JOURNAL OF PATHOLOGY

Growth Factors, Nutrient Signaling, and Cardiovascular Aging

(2012) Luigi Fontana et al.   CIRCULATION RESEARCH

MacroH2A1 Regulates the Balance between Self-Renewal and Differentiation Commitment in Embryonic and Adult Stem Cells

(2012) C. Creppe et al.   MOLECULAR AND CELLULAR BIOLOGY

Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

(2012) Etienne Dardenne et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Murine 3T3-L1 Adipocyte Cell Differentiation Model: Validated Reference Genes for qPCR Gene Expression Analysis

(2012) Tatjana Arsenijevic et al.   PLoS One

QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation

(2011) L. Novikov et al.   MOLECULAR AND CELLULAR BIOLOGY

Fat tissue, aging, and cellular senescence

(2010) Tamara Tchkonia et al.   AGING CELL

Genome-Wide Distribution of MacroH2A1 Histone Variants in Mouse Liver Chromatin

(2010) L. N. Changolkar et al.   MOLECULAR AND CELLULAR BIOLOGY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Histone variants — ancient wrap artists of the epigenome

(2010) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone variant macroH2A1 deletion in mice causes female-specific steatosis

(2010) Mathieu Boulard et al.   Epigenetics & Chromatin

The Lou/C rat: a model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue

(2009) Christelle Veyrat-Durebex et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

(2009) M. J. Gamble et al.   GENES & DEVELOPMENT

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Histone macroH2A isoforms predict the risk of lung cancer recurrence

(2009) J C Sporn et al.   ONCOGENE

Sequential changes in genome-wide DNA methylation status during adipocyte differentiation

(2007) Hideki Sakamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS