Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma

Differential Regulation and Predictive Potential of MacroH2A1 Isoforms in Colon Cancer

(2012) Judith C. Sporn et al.   AMERICAN JOURNAL OF PATHOLOGY

Conflicting Roles of Molecules in Hepatocarcinogenesis: Paradigm or Paradox

(2012) Gen-Sheng Feng   CANCER CELL

MacroH2A1 Regulates the Balance between Self-Renewal and Differentiation Commitment in Embryonic and Adult Stem Cells

(2012) C. Creppe et al.   MOLECULAR AND CELLULAR BIOLOGY

Silibinin modulates lipid homeostasis and inhibits nuclear factor kappa B activation in experimental nonalcoholic steatohepatitis

(2012) Federico Salamone et al.   Translational Research

mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart

(2011) Manlio Vinciguerra et al.   AGING CELL

New genes involved in hepatic steatosis

(2011) José M Lou-Bonafonte et al.   CURRENT OPINION IN LIPIDOLOGY

The role of JNK in the development of hepatocellular carcinoma

(2011) Madhumita Das et al.   GENES & DEVELOPMENT

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice

(2011) Kristina M. Mueller et al.   HEPATOLOGY

QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation

(2011) L. Novikov et al.   MOLECULAR AND CELLULAR BIOLOGY

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

Multiple facets of the unique histone variant macroH2A: From genomics to cell biology

(2010) Matthew J. Gamble et al.   CELL CYCLE

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

Environmental and Genetic Determinants of Fatty Liver in Humans

(2010) Konstantinos Kantartzis et al.   DIGESTIVE DISEASES

SirT1 in muscle physiology and disease: lessons from mouse models

(2010) M. Vinciguerra et al.   Disease Models & Mechanisms

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

(2010) Avnish Kapoor et al.   NATURE

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

(2010) Daniel Herranz et al.   Nature Communications

A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma

(2009) Johannes Haybaeck et al.   CANCER CELL

Sensing NAD metabolites through macro domains

(2009) Susanne Till   Frontiers in Bioscience-Landmark

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

(2009) M. J. Gamble et al.   GENES & DEVELOPMENT

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

(2009) Igor P. Pogribny et al.   JOURNAL OF HEPATOLOGY

Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN

(2009) Manlio Vinciguerra et al.   JOURNAL OF HEPATOLOGY

Histone macroH2A isoforms predict the risk of lung cancer recurrence

(2009) J C Sporn et al.   ONCOGENE

Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes

(2008) Manlio Vinciguerra et al.   HEPATOLOGY

PTEN Down-Regulation by Unsaturated Fatty Acids Triggers Hepatic Steatosis via an NF-κBp65/mTOR-Dependent Mechanism

(2007) Manlio Vinciguerra et al.   GASTROENTEROLOGY