Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

Differential Regulation and Predictive Potential of MacroH2A1 Isoforms in Colon Cancer

(2012) Judith C. Sporn et al.   AMERICAN JOURNAL OF PATHOLOGY

The Atypical Histone MacroH2A1.2 Interacts with HER-2 Protein in Cancer Cells

(2012) Xiufen Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetics in Alternative Pre-mRNA Splicing

(2011) Reini F. Luco et al.   CELL

RNA helicases p68 and p72: multifunctional proteins with important implications for cancer development

(2011) Frances V Fuller-Pace et al.   Future Oncology

Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer

(2011) F. Valdes-Mora et al.   GENOME RESEARCH

RNA Helicase p68 (DDX5) Regulates tau Exon 10 Splicing by Modulating a Stem-Loop Structure at the 5' Splice Site

(2011) A. Kar et al.   MOLECULAR AND CELLULAR BIOLOGY

QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation

(2011) L. Novikov et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone onco-modifications

(2011) J Füllgrabe et al.   ONCOGENE

Understanding splicing regulation through RNA splicing maps

(2011) Joshua T. Witten et al.   TRENDS IN GENETICS

The Redox Basis of Epigenetic Modifications: From Mechanisms to Functional Consequences

(2010) Anthony R. Cyr et al.   ANTIOXIDANTS & REDOX SIGNALING

PARP inhibitors: New tools to protect from inflammation

(2010) Vincenzo Giansanti et al.   BIOCHEMICAL PHARMACOLOGY

Metastasis: cancer cell’s escape from oxidative stress

(2010) Giovambattista Pani et al.   CANCER AND METASTASIS REVIEWS

Exon-Based Clustering of Murine Breast Tumor Transcriptomes Reveals Alternative Exons Whose Expression Is Associated with Metastasis

(2010) M. Dutertre et al.   CANCER RESEARCH

Multiple facets of the unique histone variant macroH2A: From genomics to cell biology

(2010) Matthew J. Gamble et al.   CELL CYCLE

Redox metabolism and malignancy

(2010) Christina L Grek et al.   CURRENT OPINION IN PHARMACOLOGY

Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

(2010) C. J. David et al.   GENES & DEVELOPMENT

Pleiotropic Effects of p300-mediated Acetylation on p68 and p72 RNA Helicase

(2010) Steven M. Mooney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Histone Modifications and Variants in Regulating Gene Expression in Breast Cancer

(2010) Mathieu Dalvai et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets

(2010) Raga Krishnakumar et al.   MOLECULAR CELL

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

(2010) Avnish Kapoor et al.   NATURE

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Phosphorylated p68 RNA helicase activates snail1 transcription by promoting HDAC1 dissociation from the snail1 promoter

(2010) C L Carter et al.   ONCOGENE

Redox Regulation in Cancer: A Double-edged Sword with Therapeutic Potential

(2010) Asha Acharya et al.   Oxidative Medicine and Cellular Longevity

Exon-Level Transcriptome Profiling in Murine Breast Cancer Reveals Splicing Changes Specific to Tumors with Different Metastatic Abilities

(2010) Amandine Bemmo et al.   PLoS One

Alternative splicing and breast cancer

(2010) Martin Dutertre et al.   RNA Biology

Extracellular/Microenvironmental Redox State

(2009) Luksana Chaiswing et al.   ANTIOXIDANTS & REDOX SIGNALING

Sumoylation of p68 and p72 RNA Helicases Affects Protein Stability and Transactivation Potential

(2009) Steven M. Mooney et al.   BIOCHEMISTRY

Overexpression of Extracellular Superoxide Dismutase Attenuates Heparanase Expression and Inhibits Breast Carcinoma Cell Growth and Invasion

(2009) M. L.T. Teoh et al.   CANCER RESEARCH

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

(2009) M. J. Gamble et al.   GENES & DEVELOPMENT

Cancer-associated regulation of alternative splicing

(2009) Julian P Venables et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

(2009) Gyula Timinszky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The histone variant macroH2A is an epigenetic regulator of key developmental genes

(2009) Marcus Buschbeck et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The DEAD-box protein p72 regulates ERα-/oestrogen-dependent transcription and cell growth and is associated with improved survival in ERα-positive breast cancer

(2009) N C Wortham et al.   ONCOGENE

Histone macroH2A isoforms predict the risk of lung cancer recurrence

(2009) J C Sporn et al.   ONCOGENE

Regulation of Cancer Invasion by Reactive Oxygen Species and Tks Family Scaffold Proteins

(2009) A. M. Weaver   Science Signaling

The Role of Reactive Oxygen Species in Integrin and Matrix Metalloproteinase Expression and Function

(2008) Gunbjørg Svineng et al.   CONNECTIVE TISSUE RESEARCH

Cotranscriptional Splicing Potentiates the mRNA Production from a Subset of Estradiol-Stimulated Genes

(2008) D. Bittencourt et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of H2AX in DNA damage response and human cancers

(2008) Niloo Srivastava et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS