Histone variants and lipid metabolism

Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity

(2016) Manlio Vinciguerra et al.   Aging-US

SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation

(2016) Valerio Pazienza et al.   Aging-US

Non-Alcoholic Fatty Pancreas Disease Pathogenesis: A Role for Developmental Programming and Altered Circadian Rhythms

(2014) Rebeca Carter et al.   PLoS One

Organizing the genome with H2A histone variants

(2013) Catherine B. Millar   BIOCHEMICAL JOURNAL

MacroH2A – An epigenetic regulator of cancer

(2013) Neus Cantariño et al.   CANCER LETTERS

Redox Homeostasis and Epigenetics in Non-alcoholic Fatty Liver Disease (NAFLD)

(2013) Christine Podrini et al.   CURRENT PHARMACEUTICAL DESIGN

Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21

(2013) Yu Li et al.   GASTROENTEROLOGY

Maternal obesity programs offspring nonalcoholic fatty liver disease by innate immune dysfunction in mice

(2013) Angelina Mouralidarane et al.   HEPATOLOGY

Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma

(2013) Francesca Rappa et al.   PLoS One

Lipid Droplets Control the Maternal Histone Supply of Drosophila Embryos

(2012) Zhihuan Li et al.   CURRENT BIOLOGY

Current progress on structural studies of nucleosomes containing histone H3 variants

(2012) Hitoshi Kurumizaka et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The p400/Brd8 Chromatin Remodeling Complex Promotes Adipogenesis by Incorporating Histone Variant H2A.Z at PPARγ Target Genes

(2012) Jean-Philippe Couture et al.   ENDOCRINOLOGY

Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease

(2012) Aloysious Aravinthan et al.   JOURNAL OF HEPATOLOGY

Multigenerational epigenetic adaptation of the hepatic wound-healing response

(2012) Müjdat Zeybel et al.   NATURE MEDICINE

Chromatin replication and epigenome maintenance

(2012) Constance Alabert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart

(2011) Manlio Vinciguerra et al.   AGING CELL

Precise deposition of histone H2A.Z in chromatin for genome expression and maintenance

(2011) Pierre Billon et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The double face of the histone variant H3.3

(2011) Emmanuelle Szenker et al.   CELL RESEARCH

Chromatin higher-order structures and gene regulation

(2011) Guohong Li et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Decreased nucleotide excision repair in steatotic livers associates with myeloperoxidase-immunoreactivity

(2011) Marten A. Schults et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Sirtuins, Aging, and Medicine

(2011) Leonard Guarente   NEW ENGLAND JOURNAL OF MEDICINE

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

Approaching the molecular and physiological function of macroH2A variants

(2010) Marcus Buschbeck et al.   Epigenetics

Epigenetics and the origins of paternal effects

(2010) James P. Curley et al.   HORMONES AND BEHAVIOR

Maternal obesity during pregnancy and lactation programs the development of offspring non-alcoholic fatty liver disease in mice

(2010) Jude A. Oben et al.   JOURNAL OF HEPATOLOGY

Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155 and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

(2010) Igor P Pogribny et al.   LABORATORY INVESTIGATION

Genome-Wide Distribution of MacroH2A1 Histone Variants in Mouse Liver Chromatin

(2010) L. N. Changolkar et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin Environment of Histone Variant H3.3 Revealed by Quantitative Imaging and Genome-scale Chromatin and DNA Immunoprecipitation

(2010) Erwan Delbarre et al.   MOLECULAR BIOLOGY OF THE CELL

Histone variants — ancient wrap artists of the epigenome

(2010) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Synergism between DNA methylation and macroH2A1 occupancy in epigenetic silencing of the tumor suppressor gene p16(CDKN2A)

(2010) Michal Barzily-Rokni et al.   NUCLEIC ACIDS RESEARCH

Histone variant macroH2A1 deletion in mice causes female-specific steatosis

(2010) Mathieu Boulard et al.   Epigenetics & Chromatin

Histone modification patterns and epigenetic codes

(2009) Andreas Lennartsson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

(2009) Igor P. Pogribny et al.   JOURNAL OF HEPATOLOGY

Role of the Histone Variant H2A.Z/Htz1p in TBP Recruitment, Chromatin Dynamics, and Regulated Expression of Oleate-Responsive Genes

(2009) Y. Wan et al.   MOLECULAR AND CELLULAR BIOLOGY

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

(2009) Gyula Timinszky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Epigenetics at the Epicenter of Modern Medicine

(2008) Andrew P. Feinberg   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION