TRIB1 Is Regulated Post-Transcriptionally by Proteasomal and Non-Proteasomal Pathways

Role of Tribbles Pseudokinase 1 (TRIB1) in human hepatocyte metabolism

(2016) Sébastien Soubeyrand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner

(2015) Fiona P. Bailey et al.   BIOCHEMICAL JOURNAL

Tribbles-1: a novel regulator of hepatic lipid metabolism in humans

(2015) R. C. Bauer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Pausing on Polyribosomes: Make Way for Elongation in Translational Control

(2015) Joel D. Richter et al.   CELL

Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα

(2015) Robert C. Bauer et al.   JOURNAL OF CLINICAL INVESTIGATION

Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers

(2015) Romina Briffa et al.   PLoS One

TRIB1 Supports Prostate Tumorigenesis and Tumor-Propagating Cell Survival by Regulation of Endoplasmic Reticulum Chaperone Expression

(2014) Tetsuo Mashima et al.   CANCER RESEARCH

TRIB2 inhibits Wnt/β-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, β-TrCP, COP1 and Smurf1, in liver cancer cells

(2014) Shanshan Xu et al.   FEBS LETTERS

Regulation of protein turnover by heat shock proteins

(2014) Perinur Bozaykut et al.   FREE RADICAL BIOLOGY AND MEDICINE

TRIB1 downregulates hepatic lipogenesis and glycogenesis via multiple molecular interactions

(2014) Yuumi Ishizuka et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Functional Analysis of the TRIB 1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease

(2014) Adrianna Douvris et al.   Journal of the American Heart Association

Ubiquitin E3 ligase SCFβ-TRCP regulates TRIB2 stability in liver cancer cells

(2013) Yongxia Qiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The functionally diverse roles of tribbles

(2013) Fiona Lohan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

ERK1/2 regulates hepatocyte Trib1 in response to mitochondrial dysfunction

(2013) Sébastien Soubeyrand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Bortezomib therapy-related lung disease in Japanese patients with multiple myeloma: Incidence, mortality and clinical characterization

(2013) Kazutake Yoshizawa et al.   CANCER SCIENCE

MicroRNA-224 inhibits progression of human prostate cancer by downregulating TRIB1

(2013) Zhuo-Yuan Lin et al.   INTERNATIONAL JOURNAL OF CANCER

Impaired Phosphorylation and Ubiquitination by p70 S6 Kinase (p70S6K) and Smad Ubiquitination Regulatory Factor 1 (Smurf1) Promote Tribbles Homolog 2 (TRIB2) Stability and Carcinogenic Property in Liver Cancer

(2013) Jiayi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Cotranslational Ubiquitination Pathway for Quality Control of Misfolded Proteins

(2013) Feng Wang et al.   MOLECULAR CELL

Mechanisms and function of substrate recruitment by F-box proteins

(2013) Jeffrey R. Skaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia

(2012) T. Yokoyama et al.   BLOOD

Deep proteome and transcriptome mapping of a human cancer cell line

(2011) N. Nagaraj et al.   Molecular Systems Biology

Determinants of translation efficiency and accuracy

(2011) H. Gingold et al.   Molecular Systems Biology

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

(2011) John C Chambers et al.   NATURE GENETICS

Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis

(2010) T. Yokoyama et al.   BLOOD

Differential ability of Tribbles family members to promote degradation of C/EBP  and induce acute myelogenous leukemia

(2010) P. H. Dedhia et al.   BLOOD

Trib1 is a lipid- and myocardial infarction–associated gene that regulates hepatic lipogenesis and VLDL production in mice

(2010) Ralph Burkhardt et al.   JOURNAL OF CLINICAL INVESTIGATION

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells

(2008) L. V. Sharova et al.   DNA RESEARCH

Identification and Characterization of a General Nuclear Translocation Signal in Signaling Proteins

(2008) Dana Chuderland et al.   MOLECULAR CELL

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

(2008) Cristen J Willer et al.   NATURE GENETICS