Metformin Induces Cell Cycle Arrest, Reduced Proliferation, Wound Healing Impairment In Vivo and Is Associated to Clinical Outcomes in Diabetic Foot Ulcer Patients

Metformin attenuated the inflammation after renal ischemia/reperfusion and suppressed apoptosis of renal tubular epithelial cell in rats

(2015) Zhi-shun Wang et al.   Acta Cirurgica Brasileira

Selective Inhibition of Deactivated Mitochondrial Complex I by Biguanides

(2015) Satoshi Matsuzaki et al.   BIOCHEMISTRY

Predictors of Lower-Extremity Amputation in Patients With an Infected Diabetic Foot Ulcer

(2015) Kristy Pickwell et al.   DIABETES CARE

Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions

(2015) Alessandra Silvestri et al.   PLoS One

Immune-mediated antitumor effect by type 2 diabetes drug, metformin

(2015) Shingo Eikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene Network Analysis of Glucose Linked Signaling Pathways and Their Role in Human Hepatocellular Carcinoma Cell Growth and Survival in HuH7 and HepG2 Cell Lines

(2015) Emmanuelle Berger et al.   Biomed Research International

Use of insulin-like growth factor in the healing of open wounds in diabetic and non-diabetic rats

(2015) Rosi Aparecida Nunes Achar et al.   Acta Cirurgica Brasileira

Metformin Ameliorates Inflammatory Bowel Disease by Suppression of the STAT3 Signaling Pathway and Regulation of the between Th17/Treg Balance

(2015) Seon-Yeong Lee et al.   PLoS One

Metformin Suppresses Ovarian Cancer Growth and Metastasis with Enhancement of Cisplatin Cytotoxicity In Vivo

(2015) Ramandeep Rattan et al.   NEOPLASIA

Enhancement of Diabetic Wound Repair Using Biodegradable Nanofibrous Metformin-Eluting Membranes: in Vitro and in Vivo

(2014) Cheng-Hung Lee et al.   ACS Applied Materials & Interfaces

Triggering Factors of Primary Care Costs in the Years Following Type 2 Diabetes Diagnosis in Mexico

(2014) Angélica Castro-Ríos et al.   ARCHIVES OF MEDICAL RESEARCH

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria

(2014) Hannah R. Bridges et al.   BIOCHEMICAL JOURNAL

Metformin and Cancer Risk and Mortality: A Systematic Review and Meta-analysis Taking into Account Biases and Confounders

(2014) S. Gandini et al.   Cancer Prevention Research

Cost-of-illness studies of diabetes mellitus: A systematic review

(2014) Charmaine S. Ng et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Mechanism of Metformin-dependent Inhibition of Mammalian Target of Rapamycin (mTOR) and Ras Activity in Pancreatic Cancer

(2014) Vijayalekshmi Nair et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The independent contribution of diabetic foot ulcer on lower extremity amputation and mortality risk

(2014) Daniela Martins-Mendes et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

Metformin as adjunct antituberculosis therapy

(2014) A. Singhal et al.   Science Translational Medicine

Risk Factors Associated with Amputation-Free Survival in Patient with Diabetic Foot Ulcers

(2014) Sung Hun Won et al.   YONSEI MEDICAL JOURNAL

Metformin lowers Ser-129 phosphorylated α-synuclein levels via mTOR-dependent protein phosphatase 2A activation

(2014) B I Pérez-Revuelta et al.   Cell Death & Disease

Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancer

(2014) Kevin M. Schuler et al.   Cancer Medicine

Global estimates of diabetes prevalence for 2013 and projections for 2035

(2013) L. Guariguata et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Metformin and Breast Cancer Risk

(2013) Sara Gandini et al.   JOURNAL OF CLINICAL ONCOLOGY

Epidemiology of Foot Ulceration and Amputation

(2013) David J. Margolis et al.   MEDICAL CLINICS OF NORTH AMERICA

In vitro and in vivoanti-tumor effect of metformin as a novel therapeutic agent in human oral squamous cell carcinoma

(2012) Qingqiong Luo et al.   BMC CANCER

Health-Related Quality of Life Using the EuroQol 5D Questionnaire in Korean Patients with Type 2 Diabetes

(2012) Woo Je Lee et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Cancer Risk in Diabetic Patients Treated with Metformin: A Systematic Review and Meta-analysis

(2012) Hiroshi Noto et al.   PLoS One

The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells

(2011) Alejandro Vazquez-Martin et al.   CELL CYCLE

Cellular and molecular mechanisms of metformin: an overview

(2011) Benoit Viollet et al.   CLINICAL SCIENCE

Estimation of the impact of diabetes-related complications on health utilities for patients with type 2 diabetes in Ontario, Canada

(2011) Daria J. O’Reilly et al.   QUALITY OF LIFE RESEARCH

Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis

(2010) A. DeCensi et al.   Cancer Prevention Research

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

(2010) Adem Kalender et al.   Cell Metabolism

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

(2008) I Ben Sahra et al.   ONCOGENE