Metformin Ameliorates Inflammatory Bowel Disease by Suppression of the STAT3 Signaling Pathway and Regulation of the between Th17/Treg Balance

Metformin: Its emerging role in oncology

(2014) Dragan Micic et al.   Hormones-International Journal of Endocrinology and Metabolism

Red Ginseng Extract Ameliorates Autoimmune Arthritis via Regulation of STAT3 Pathway, Th17/Treg Balance, and Osteoclastogenesis in Mice and Human

(2014) JooYeon Jhun et al.   MEDIATORS OF INFLAMMATION

TGF-Beta Signaling Manipulation as Potential Therapy for IBD

(2013) Irene Marafini et al.   CURRENT DRUG TARGETS

Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth

(2013) H. A. Hirsch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Th17 Cells

(2012) Mohan S. Maddur et al.   AMERICAN JOURNAL OF PATHOLOGY

Th17 cells: interactions with predisposing factors in the immunopathogenesis of inflammatory bowel disease

(2012) Ali Raza et al.   Expert Review of Clinical Immunology

Identification of potent small-molecule inhibitors of STAT3 with anti-inflammatory properties in RAW 264.7 macrophages

(2012) Hemachander Capiralla et al.   FEBS Journal

Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers

(2012) Megan E. Himmel et al.   IMMUNOLOGY

Targeting IL-17 and TH17 cells in chronic inflammation

(2012) Pierre Miossec et al.   NATURE REVIEWS DRUG DISCOVERY

Autoimmunity in 2010

(2011) Carlo Selmi   AUTOIMMUNITY REVIEWS

Stat3 Phosphorylation Mediates Resistance of Primary Human T Cells to Regulatory T Cell Suppression

(2011) W. A. Goodman et al.   JOURNAL OF IMMUNOLOGY

Zinc suppresses Th17 development via inhibition of STAT3 activation

(2010) Chika Kitabayashi et al.   INTERNATIONAL IMMUNOLOGY

A Novel Mouse Model of Inflammatory Bowel Disease Links Mammalian Target of Rapamycin-Dependent Hyperproliferation of Colonic Epithelium to Inflammation-Associated Tumorigenesis

(2009) Lin Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease

(2009) Nicola Eastaff-Leung et al.   JOURNAL OF CLINICAL IMMUNOLOGY

VEGF-A Links Angiogenesis and Inflammation in Inflammatory Bowel Disease Pathogenesis

(2008) Franco Scaldaferri et al.   GASTROENTEROLOGY

STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25− effector T cells

(2008) Laura Passerini et al.   INTERNATIONAL IMMUNOLOGY

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

(2008) Liang Zhou et al.   NATURE