Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancer

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Effects of metformin on endometrial cancer cell growth in vivo: A preoperative prospective trial

(2014) Akira Mitsuhashi et al.   CANCER

Metabolic Reprogramming of Macrophages

(2014) Alex J. Freemerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemopreventive effects of metformin on obesity-associated endometrial proliferation

(2013) Qian Zhang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Metformin Lowers Plasma Triglycerides by Promoting VLDL-Triglyceride Clearance by Brown Adipose Tissue in Mice

(2013) J. J. Geerling et al.   DIABETES

Metformin use and endometrial cancer survival

(2013) Nicole S. Nevadunsky et al.   GYNECOLOGIC ONCOLOGY

Metformin is associated with improved survival in endometrial cancer

(2013) Emily M. Ko et al.   GYNECOLOGIC ONCOLOGY

Type I and II Endometrial Cancers: Have They Different Risk Factors?

(2013) Veronica Wendy Setiawan et al.   JOURNAL OF CLINICAL ONCOLOGY

Metformin Is Associated With Survival Benefit in Cancer Patients With Concurrent Type 2 Diabetes: A Systematic Review and Meta-Analysis

(2013) M. Yin et al.   ONCOLOGIST

Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review

(2013) Monica Franciosi et al.   PLoS One

Does Metformin affect ER, PR, IGF-1R, β-catenin and PAX-2 expression in women with diabetes mellitus and endometrial cancer?

(2013) Anna Markowska et al.   Diabetology & Metabolic Syndrome

Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study

(2012) Saroj Niraula et al.   BREAST CANCER RESEARCH AND TREATMENT

Obesity and Overfeeding Affecting Both Tumor and Systemic Metabolism Activates the Progesterone Receptor to Contribute to Postmenopausal Breast Cancer

(2012) E. D. Giles et al.   CANCER RESEARCH

Mortality After Incident Cancer in People With and Without Type 2 Diabetes: Impact of metformin on survival

(2012) C. J. Currie et al.   DIABETES CARE

Metformin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and modulation of the mTOR pathway

(2012) Rabbie K. Hanna et al.   GYNECOLOGIC ONCOLOGY

The inflammation highway: metabolism accelerates inflammatory traffic in obesity

(2012) Amy R. Johnson et al.   IMMUNOLOGICAL REVIEWS

Anti-diabetic activities of Acanthopanax senticosus polysaccharide (ASP) in combination with metformin

(2012) Jianfang Fu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Dual Effect of Metformin on Breast Cancer Proliferation in a Randomized Presurgical Trial

(2012) Bernardo Bonanni et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects

(2012) M A Pierotti et al.   ONCOGENE

Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects

(2012) Arian Emami Riedmaier et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Investigating Metformin for Cancer Prevention and Treatment: The End of the Beginning

(2012) Michael N. Pollak   Cancer Discovery

Understanding obesity and endometrial cancer risk: opportunities for prevention

(2011) Rosemarie E. Schmandt et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial

(2011) Sirwan Hadad et al.   BREAST CANCER RESEARCH AND TREATMENT

Emerging therapeutic targets in endometrial cancer

(2011) Konstantin J. Dedes et al.   Nature Reviews Clinical Oncology

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

(2011) Z. J. Reitman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser-554 and -induced lipolysis in human adipocytes

(2011) Jean Grisouard et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Metformin Activates AMP Kinase through Inhibition of AMP Deaminase

(2010) Jiangyong Ouyang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin promotes progesterone receptor expression via inhibition of mammalian target of rapamycin (mTOR) in endometrial cancer cells

(2010) Ya Xie et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

Dietary energy availability affects primary and metastatic breast cancer and metformin efficacy

(2009) Kathryn N. Phoenix et al.   BREAST CANCER RESEARCH AND TREATMENT

Endometrial cancer and obesity: Epidemiology, biomarkers, prevention and survivorship

(2009) Amanda Nickles Fader et al.   GYNECOLOGIC ONCOLOGY

Promising novel therapies for the treatment of endometrial cancer

(2009) Paola A. Gehrig et al.   GYNECOLOGIC ONCOLOGY

Metformin is a potent inhibitor of endometrial cancer cell proliferation—implications for a novel treatment strategy

(2009) Leigh A. Cantrell et al.   GYNECOLOGIC ONCOLOGY

Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth

(2008) C. Algire et al.   ENDOCRINE-RELATED CANCER

Mechanisms of metformin inhibiting lipolytic response to isoproterenol in primary rat adipocytes

(2008) Tingting Zhang et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Analysis of the adult human plasma metabolome

(2008) Kay A Lawton et al.   PHARMACOGENOMICS