Integrins regulate hERG1 dynamics by girdin-dependent Gαi3: signaling and modeling in cancer cells
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Integrins regulate hERG1 dynamics by girdin-dependent Gαi3: signaling and modeling in cancer cells
Authors
Keywords
-
Journal
Life Science Alliance
Volume 7, Issue 1, Pages e202302135
Publisher
Life Science Alliance, LLC
Online
2023-11-04
DOI
10.26508/lsa.202302135
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Combination Therapy with a Bispecific Antibody Targeting the hERG1/β1 Integrin Complex and Gemcitabine in Pancreatic Ductal Adenocarcinoma
- (2023) Tiziano Lottini et al. Cancers
- Cardiac safety assessment of a novel recombinant bispecific antibody targeting the ether-à-go-go related gene 1 (hERG1)-β1 integrin macromolecular complex
- (2023) Lorenzo Santini et al. Frontiers in Pharmacology
- Dynamics and physiological meaning of complexes between ion channels and integrin receptors: the case of Kv11.1
- (2022) Andrea Becchetti et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Prognostic role of hERG1 Potassium Channels in Neuroendocrine Tumours of the Ileum and Pancreas
- (2022) Jessica Iorio et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The role of potassium channels in tumours of the gastrointestinal tract: a focus on the human ether‐à‐go‐go related gene 1 channels
- (2022) Annarosa Arcangeli et al. JOURNAL OF PHYSIOLOGY-LONDON
- The Interaction between hERG1 and β1 Integrins Modulates hERG1 Current in Different Pathological Cell Models
- (2022) Ginevra Chioccioli Altadonna et al. Membranes
- The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function
- (2021) Ahmad F Alghanem et al. eLife
- Enhanced substrate stress relaxation promotes filopodia-mediated cell migration
- (2021) Kolade Adebowale et al. NATURE MATERIALS
- Harnessing the hERG1/β1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers
- (2021) Claudia Duranti et al. MOLECULAR CANCER THERAPEUTICS
- Differences in cortical contractility between healthy epithelial and cancerous mesenchymal breast cells
- (2021) Enrico Warmt et al. NEW JOURNAL OF PHYSICS
- Expression and purification of a novel single-chain diabody (scDb-hERG1/β1) from Pichia pastoris transformants
- (2021) Claudia Duranti et al. PROTEIN EXPRESSION AND PURIFICATION
- Cell–extracellular matrix dynamics
- (2021) Andrew D Doyle et al. PHYSICAL BIOLOGY
- Clarithromycin inhibits autophagy in colorectal cancer by regulating the hERG1 potassium channel interaction with PI3K
- (2020) Giulia Petroni et al. Cell Death & Disease
- Nonequilibrium Thermodynamics in Cell Biology: Extending Equilibrium Formalism to Cover Living Systems
- (2020) Xiaona Fang et al. Annual Review of Biophysics
- Actin Cell Cortex: Structure and Molecular Organization
- (2020) Tatyana M. Svitkina TRENDS IN CELL BIOLOGY
- Cytoskeletal Crosstalk in Cell Migration
- (2020) Shailaja Seetharaman et al. TRENDS IN CELL BIOLOGY
- KV11.1 Potassium Channel and the Na+/H+ Antiporter NHE1 Modulate Adhesion-Dependent Intracellular pH in Colorectal Cancer Cells
- (2020) Jessica Iorio et al. Frontiers in Pharmacology
- EMT‐Induced Cell‐Mechanical Changes Enhance Mitotic Rounding Strength
- (2020) Kamran Hosseini et al. Advanced Science
- Ion Channel Conformations Regulate Integrin-Dependent Signaling
- (2019) Andrea Becchetti et al. TRENDS IN CELL BIOLOGY
- The Activity of Kv 11.1 Potassium Channel Modulates F-Actin Organization During Cell Migration of Pancreatic Ductal Adenocarcinoma Cells
- (2019) Sagar Manoli et al. Cancers
- Integrin Signaling in Cancer: Mechanotransduction, Stemness, Epithelial Plasticity, and Therapeutic Resistance
- (2019) Jonathan Cooper et al. CANCER CELL
- HERG1 promotes esophageal squamous cell carcinoma growth and metastasis through TXNDC5 by activating the PI3K/AKT pathway
- (2019) Hongqiang Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1
- (2017) Tullio Genova et al. JOURNAL OF CELL BIOLOGY
- β -Arrestin-Mediated Regulation of the Human Ether-a-go-go -Related Gene Potassium Channel
- (2017) Matthew G. Sangoi et al. MOLECULAR PHARMACOLOGY
- The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression
- (2017) Andrea Becchetti et al. Science Signaling
- The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression
- (2017) Andrea Becchetti et al. Science Signaling
- Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time
- (2016) Nicolas Aznar et al. BIOESSAYS
- hERG quality control and the long QT syndrome
- (2016) Brian Foo et al. JOURNAL OF PHYSIOLOGY-LONDON
- Nonequilibrium Thermodynamics of Chemical Reaction Networks: Wisdom from Stochastic Thermodynamics
- (2016) Riccardo Rao et al. Physical Review X
- Modeling Signaling Networks to Advance New Cancer Therapies
- (2015) Julio Saez-Rodriguez et al. Annual Review of Biomedical Engineering
- hERG1 channels drive tumour malignancy and may serve as prognostic factor in pancreatic ductal adenocarcinoma
- (2015) E Lastraioli et al. BRITISH JOURNAL OF CANCER
- GIV/Girdin Transmits Signals from Multiple Receptors by Triggering Trimeric G Protein Activation
- (2015) Mikel Garcia-Marcos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin
- (2015) Anthony Leyme et al. JOURNAL OF CELL BIOLOGY
- Mechanical properties of fibroblasts depend on level of cancer transformation
- (2014) Yu.M. Efremov et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
- (2014) Zhaozhu Qiu et al. CELL
- hERG1 Channels Regulate VEGF-A Secretion in Human Gastric Cancer: Clinicopathological Correlations and Therapeutical Implications
- (2014) O. Crociani et al. CLINICAL CANCER RESEARCH
- Quantitative image analysis tool to study the plasma membrane localization of proteins and cortical actin in neuroendocrine cells
- (2014) Julia Kurps et al. JOURNAL OF NEUROSCIENCE METHODS
- Mechanotransduction and extracellular matrix homeostasis
- (2014) Jay D. Humphrey et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- hERG1 Channels and Glut-1 as Independent Prognostic Indicators of Worse Outcome in Stage I and II Colorectal Cancer: A Pilot Study
- (2014) Elena Lastraioli et al. Translational Oncology
- Integrins in mechanotransduction
- (2013) Tyler D Ross et al. CURRENT OPINION IN CELL BIOLOGY
- hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer
- (2013) Olivia Crociani et al. Scientific Reports
- Inside-out, outside-in, and inside–outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction
- (2012) Bo Shen et al. CURRENT OPINION IN CELL BIOLOGY
- Negative regulators of integrin activity
- (2012) J. Pouwels et al. JOURNAL OF CELL SCIENCE
- Sig1R Protein Regulates hERG Channel Expression through a Post-translational Mechanism in Leukemic Cells
- (2011) David Crottès et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Integrin Structure, Activation, and Interactions
- (2011) I. D. Campbell et al. Cold Spring Harbor Perspectives in Biology
- Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers
- (2010) S. Pillozzi et al. BLOOD
- G Protein Subunit G 13 Binds to Integrin IIb 3 and Mediates Integrin "Outside-In" Signaling
- (2010) H. Gong et al. SCIENCE
- An Actin-Binding Protein Girdin Regulates the Motility of Breast Cancer Cells
- (2008) P. Jiang et al. CANCER RESEARCH
- Activation of Gαi3 triggers cell migration via regulation of GIV
- (2008) Pradipta Ghosh et al. JOURNAL OF CELL BIOLOGY
- Identification of a Posttranslational Mechanism for the Regulation of hERG1 K+ Channel Expression and hERG1 Current Density in Tumor Cells
- (2008) L. Guasti et al. MOLECULAR AND CELLULAR BIOLOGY
- Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin
- (2008) Tomoya Kitamura et al. NATURE CELL BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started