HERG1 promotes esophageal squamous cell carcinoma growth and metastasis through TXNDC5 by activating the PI3K/AKT pathway

hERG1 channel expression associates with molecular subtypes and prognosis in breast cancer

(2018) Jessica Iorio et al.   Cancer Cell International

Novel carbazole sulfonamide microtubule-destabilizing agents exert potent antitumor activity against esophageal squamous cell carcinoma

(2018) Fangfei Niu et al.   CANCER LETTERS

Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast ActivationNovelty and Significance

(2018) Ying-Chun Shih et al.   CIRCULATION RESEARCH

Ether-à-go-go K+ channels: effective modulators of neuronal excitability

(2018) Christiane K. Bauer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell CarcinomaIn Vitroand Patient-Derived XenograftsIn Vivo

(2018) Mengqiu Song et al.   MOLECULAR CANCER THERAPEUTICS

Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study

(2018) Laura L. Perissinotti et al.   Frontiers in Physiology

MKRN2 inhibits migration and invasion of non-small-cell lung cancer by negatively regulating the PI3K/Akt pathway

(2018) Jun Jiang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells

(2017) Masahiro Yoshioka et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression

(2017) Andrea Becchetti et al.   Science Signaling

The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression

(2017) Andrea Becchetti et al.   Science Signaling

A Propensity-matched Analysis Comparing Survival After Esophagectomy Followed by Adjuvant Chemoradiation to Surgery Alone for Esophageal Squamous Cell Carcinoma

(2016) Jwu-Yun Hwang et al.   ANNALS OF SURGERY

Elevated Orai1 and STIM1 expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer

(2016) Jianling Xia et al.   CANCER LETTERS

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

hERG1 potassium channel in cancer cells: a tool to reprogram immortality

(2016) Saverio Gentile   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Voltage-gated sodium channel Nav1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1

(2016) Jianling Xia et al.   INTERNATIONAL JOURNAL OF CANCER

Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma

(2016) Jia-Jie Hao et al.   NATURE GENETICS

Silencing of hERG1 Gene Inhibits Proliferation and Invasion, and Induces Apoptosis in Human Osteosarcoma Cells by Targeting the NF-κB Pathway

(2016) Wenrong Zeng et al.   Journal of Cancer

hERG1 channels drive tumour malignancy and may serve as prognostic factor in pancreatic ductal adenocarcinoma

(2015) E Lastraioli et al.   BRITISH JOURNAL OF CANCER

Stimulation of hERG1 channel activity promotes a calcium-dependent degradation of cyclin E2, but not cyclin E1, in breast cancer cells

(2015) Mathew Perez-Neut et al.   Oncotarget

hERG1 Potassium Channels: Novel Biomarkers in Human Solid Cancers

(2015) Elena Lastraioli et al.   Biomed Research International

Re-trafficking of hERG reverses long QT syndrome 2 phenotype in human iPS-derived cardiomyocytes

(2014) Ashish Mehta et al.   CARDIOVASCULAR RESEARCH

hERG1 Channels Regulate VEGF-A Secretion in Human Gastric Cancer: Clinicopathological Correlations and Therapeutical Implications

(2014) O. Crociani et al.   CLINICAL CANCER RESEARCH

Recent advances in the understanding and management of long QT syndrome

(2014) Shashank P. Behere et al.   CURRENT OPINION IN PEDIATRICS

The role of TXNDC5 in castration-resistant prostate cancer—involvement of androgen receptor signaling pathway

(2014) L Wang et al.   ONCOGENE

An immunohistochemical study of thioredoxin domain-containing 5 expression in gastric adenocarcinoma

(2014) ZHIMING WU et al.   Oncology Letters

Investigating a pathogenic role for TXNDC5 in tumors

(2013) XIAOTIAN CHANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells

(2013) M. A. Nieto   SCIENCE

hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer

(2013) Olivia Crociani et al.   Scientific Reports

Regulation of the voltage-insensitive step of HERG activation by extracellular pH

(2010) Qinlian Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY