The chemistry and biology of guanidine natural products

Newts are Toxic, but They were Pressured into it: Butch Brodie’s Studies of Co-Evolutionary Arms Races

(2017) Craig R. Williams   TRANSACTIONS OF THE ROYAL SOCIETY OF SOUTH AUSTRALIA

Community Ecology and the Evolution of Molecules of Keystone Significance

(2016) Ryan P. Ferrer et al.   BIOLOGICAL BULLETIN

Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

(2014) Ulrike Leurs et al.   ACS Chemical Biology

Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome

(2014) Arren Z. Washington et al.   ACS Chemical Biology

Pseudoaeruginosins, Nonribosomal Peptides in Nodularia spumigena

(2014) Liwei Liu et al.   ACS Chemical Biology

Effect of side chain length on intrahelical interactions between carboxylate- and guanidinium-containing amino acids

(2014) Hsiou-Ting Kuo et al.   AMINO ACIDS

Cyanobacteria, microcystins and cylindrospermopsin in public drinking supply reservoirs of Brazil

(2014) MARIA DO CARMO BITTENCOURT-OLIVEIRA et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

NMR Fingerprints of the Drug-like Natural-Product Space Identify Iotrochotazine A: A Chemical Probe to Study Parkinson’s Disease

(2014) Tanja Grkovic et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C5-C10 Directly Bonded Tetrodotoxin Analogues: Possible Biosynthetic Precursors of Tetrodotoxin From Newts

(2014) Yuta Kudo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric NH Insertion of Secondary and Primary Anilines under the Catalysis of Palladium and Chiral Guanidine Derivatives

(2014) Yin Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Rapid Synthesis of 4-Oxazolidinones: Total Synthesis of Synoxazolidinones A and B

(2014) Nataliia V. Shymanska et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Paenilamicin: Structure and Biosynthesis of a Hybrid Nonribosomal Peptide/Polyketide Antibiotic from the Bee PathogenPaenibacillus larvae

(2014) Sebastian Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Saxitoxin

(2014) Arun P. Thottumkara et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biosynthesis of the β-Methylarginine Residue of Peptidyl Nucleoside Arginomycin in Streptomyces arginensis NRRL 15941

(2014) Jun Feng et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Guanidine Motif in Biologically Active Peptides

(2014) Juan V. Alegre-Requena et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Novel Tartrate-Based Guanidines for Enantioselective Fluorination of 1,3-Dicarbonyl and α-Cyano Carbonyl Compounds

(2014) Liwei Zou et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

The Chemistry of Guanidine, Guanidinium, and Guanidinate Compounds

(2014) Choon Hong Tan et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Development of Novel Guanidine–Bisurea Bifunctional Organocatalysts and their Application to Asymmetric α-Hydroxylation of Tetralone-derived β-Keto Esters

(2014) Minami Odagi et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Guanidino groups greatly enhance the action of antimicrobial peptidomimetics against bacterial cytoplasmic membranes

(2014) Konstantin Andreev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Synthesis and pharmacological evaluation of optically pure, novel carbonyl guanidine derivatives as dual 5-HT2B and 5-HT7 receptor antagonists

(2014) Ayako Moritomo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and structure–activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists. Part 2

(2014) Ayako Moritomo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and biological evaluation of scaffold-based tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4)

(2014) Zack G. Zachariassen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Effect of each guanidinium group on the RNA recognition and cellular uptake of Tat-derived peptides

(2014) Cheng-Hsun Wu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Imidazo[1,2- a ]pyridine-based peptidomimetics as inhibitors of Akt

(2014) Young B. Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Poly-guanidinoethylphenylethers organised around a benzene ring: Synthesis and evaluation of their antibacterial and cytotoxic properties

(2014) Hugues Massimba Dibama et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity

(2014) Giorgio Maccari et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Second generation, arginine-rich (R–X′–R)4-type cell-penetrating α–ω–α-peptides with constrained, chiral ω-amino acids (X′) for enhanced cargo delivery into cells

(2014) Kiran M. Patil et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The insulin secretory action of novel polycyclic guanidines: Discovery through open innovation phenotypic screening, and exploration of structure–activity relationships

(2014) Michael B. Shaghafi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Docking and Quantitative Structure Activity Relationship studies of Acyl Guanidines as β-Secretase (BACE1) Inhibitor

(2014) Yu Jin Hwang et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Total synthesis of (+)-cylindradine A

(2014) Makoto Iwata et al.   CHEMICAL COMMUNICATIONS

Highly enantioselective synthesis of α-azido-β-hydroxy methyl ketones catalyzed by a cooperative proline–guanidinium salt system

(2014) Ángel Martínez-Castañeda et al.   CHEMICAL COMMUNICATIONS

Novel tartrate-derived guanidine-catalyzed highly enantio- and diastereoselective Michael addition of 3-substituted oxindoles to nitroolefins

(2014) Liwei Zou et al.   CHEMICAL COMMUNICATIONS

Guanidines: from classical approaches to efficient catalytic syntheses

(2014) Carlos Alonso-Moreno et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of 5,6,11-Trideoxytetrodotoxin

(2014) Masaatsu Adachi et al.   CHEMISTRY LETTERS

1,6-Addition Reaction of 5H-Oxazol-4-ones to Conjugated Dienones Catalyzed by Chiral Guanidines

(2014) Akane Morita et al.   CHEMISTRY LETTERS

Total Synthesis of Chiriquitoxin, an Analogue of Tetrodotoxin Isolated from the Skin of a Dart Frog

(2014) Masaatsu Adachi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of 5- and 8-Deoxytetrodotoxin

(2014) Yoshiki Satake et al.   Chemistry-An Asian Journal

Development of the First Oral Bioprecursors of Bis-alkylguanidine Antimalarial Drugs

(2014) Mélissa Degardin et al.   ChemMedChem

Synthetic Approaches to Heterocyclic Guanidines with Biological Activity: An Update

(2014) Sandra Zarate et al.   CURRENT ORGANIC CHEMISTRY

Guanidinium-based derivatives: Searching for new kinase inhibitors

(2014) Elena Diez-Cecilia et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure–function relationships of Nile blue (EtNBS) derivatives as antimicrobial photosensitizers

(2014) Daniela Vecchio et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

7-Deoxy-desulfo-cylindrospermopsin and 7-deoxy-desulfo-12-acetylcylindrospermopsin: Two new cylindrospermopsin analogs isolated from a Thai strain of Cylindrospermopsis raciborskii

(2014) Katie M. Wimmer et al.   HARMFUL ALGAE

Catalytic Performance of Polystyrene-BoundChibaGDerivatives as Guanidine Organobases in AsymmetricMichaelAdditions

(2014) Tsutomu Ishikawa et al.   HELVETICA CHIMICA ACTA

First Total Synthesis ofN-(3-Guanidinopropyl)-2-(4-hydroxyphenyl)-2-oxoacetamide

(2014) Satish S. More et al.   HELVETICA CHIMICA ACTA

Military potential of biological toxins

(2014) Xiujuan Zhang et al.   Journal of Applied Biomedicine

Structure–Activity Relationship Studies of N-Methylated and N-Hydroxylated Spider Polyamine Toxins as Inhibitors of Ionotropic Glutamate Receptors

(2014) Niels G. Nørager et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nonpeptide Small Molecule Agonist and Antagonist Original Leads for Neuropeptide FF1 and FF2 Receptors

(2014) V. Blair Journigan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Propylene Cross-Bridged Macrocyclic Bifunctional Chelator: A New Design for Facile Bioconjugation and Robust 64Cu Complex Stability

(2014) Darpan N. Pandya et al.   JOURNAL OF MEDICINAL CHEMISTRY

Oseltamivir Analogues Bearing N-Substituted Guanidines as Potent Neuraminidase Inhibitors

(2014) Caitlin A. Mooney et al.   JOURNAL OF MEDICINAL CHEMISTRY

Physicochemically and Pharmacokinetically Stable Nonapeptide KISS1 Receptor Agonists with Highly Potent Testosterone-Suppressive Activity

(2014) Taiji Asami et al.   JOURNAL OF MEDICINAL CHEMISTRY

99mTc-Labeled Vasopressin Peptide as a Radiopharmaceutical for Small-Cell Lung Cancer (SCLC) Diagnosis

(2014) Ewa Gniazdowska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Selective Hexapeptide Agonists to Human Neuromedin U Receptors Types 1 and 2

(2014) Kentaro Takayama et al.   JOURNAL OF MEDICINAL CHEMISTRY

Amino Acid Modified Xanthone Derivatives: Novel, Highly Promising Membrane-Active Antimicrobials for Multidrug-Resistant Gram-Positive Bacterial Infections

(2014) Jun-Jie Koh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Transition State Mimetics of the Plasmodium Export Element Are Potent Inhibitors of Plasmepsin V from P. falciparum and P. vivax

(2014) Brad E. Sleebs et al.   JOURNAL OF MEDICINAL CHEMISTRY

Unexpected DNA Affinity and Sequence Selectivity through Core Rigidity in Guanidinium-Based Minor Groove Binders

(2014) Padraic S. Nagle et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli

(2014) Rasmus D. Jahnsen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nostosins, Trypsin Inhibitors Isolated from the Terrestrial Cyanobacterium Nostoc sp. Strain FSN

(2014) Liwei Liu et al.   JOURNAL OF NATURAL PRODUCTS

In Vitro Antibacterial Activity of Prenylated Guanidine Alkaloids from Pterogyne nitens and Synthetic Analogues

(2014) Aline Coqueiro et al.   JOURNAL OF NATURAL PRODUCTS

Isolation of 6-Deoxytetrodotoxin from the Pufferfish, Takifugu pardalis, and a Comparison of the Effects of the C-6 and C-11 Hydroxy Groups of Tetrodotoxin on Its Activity

(2014) Yuta Kudo et al.   JOURNAL OF NATURAL PRODUCTS

Autumnalamide, a Prenylated Cyclic Peptide from the Cyanobacterium Phormidium autumnale, Acts on SH-SY5Y Cells at the Mitochondrial Level

(2014) Coralie Audoin et al.   JOURNAL OF NATURAL PRODUCTS

Netamines H–N, Tricyclic Alkaloids from the Marine Sponge Biemna laboutei and Their Antimalarial Activity

(2014) Emmanuelle Gros et al.   JOURNAL OF NATURAL PRODUCTS

Antifouling Compounds from the Sub-Arctic Ascidian Synoicum pulmonaria: Synoxazolidinones A and C, Pulmonarins A and B, and Synthetic Analogues

(2014) Rozenn Trepos et al.   JOURNAL OF NATURAL PRODUCTS

On Guanidinium and Cellular Uptake

(2014) Ezequiel Wexselblatt et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis and Stereochemistry Revision of Mannopeptimycin Aglycone

(2014) Shinichiro Fuse et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-Permeable Bicyclic Peptide Inhibitors against Intracellular Proteins

(2014) Wenlong Lian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fundamental Molecular Mechanism for the Cellular Uptake of Guanidinium-Rich Molecules

(2014) Henry D. Herce et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tricyclic Guanidine Alkaloids from the Marine Sponge Acanthella cavernosa that Stabilize the Tumor Suppressor PDCD4

(2014) Tanja Grkovic et al.   Marine Drugs

Parallel Evolution of Tetrodotoxin Resistance in Three Voltage-Gated Sodium Channel Genes in the Garter Snake Thamnophis sirtalis

(2014) Joel W. McGlothlin et al.   MOLECULAR BIOLOGY AND EVOLUTION

An alternative, arginase-independent pathway for arginine metabolism inKluyveromyces lactisinvolves guanidinobutyrase as a key enzyme

(2014) G. Romagnoli et al.   MOLECULAR MICROBIOLOGY

Cell-Penetrating, Guanidinium-Rich Molecular Transporters for Overcoming Efflux-Mediated Multidrug Resistance

(2014) Jessica R. Vargas et al.   MOLECULAR PHARMACEUTICS

Recent progress in neuroactive marine natural products

(2014) Ryuichi Sakai et al.   NATURAL PRODUCT REPORTS

Catalytic, enantioselective vinylogous Michael reactions

(2014) Christoph Schneider et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A New Stereocontrolled Total Synthesis of the Mast Cell Inhibitory Alkaloid, (+)-Monanchorin, via the Wittig Reaction of a Stabilized Ylide with a Cyclic Guanidine Hemiaminal

(2014) Karl J. Hale et al.   ORGANIC LETTERS

Synthesis of Bicyclic Guanidines via Cascade Hydroamination/Michael Additions of Mono-N-acryloylpropargylguanidines

(2014) Ki-Hyeok Kwon et al.   ORGANIC LETTERS

A Mild Method for the Synthesis of Carbamate-Protected Guanidines Using the Burgess Reagent

(2014) Toshikatsu Maki et al.   ORGANIC LETTERS

Total Synthesis of Polydiscamides B, C, and D via a Convergent Native Chemical Ligation–Oxidation Strategy

(2014) Gajan Santhakumar et al.   ORGANIC LETTERS

Chlorocatechelins A and B from Streptomyces sp.: New Siderophores Containing Chlorinated Catecholate Groups and an Acylguanidine Structure

(2014) Shinji Kishimoto et al.   ORGANIC LETTERS

Catalytic α-Monoallylation of Aryl Acetonitriles

(2014) Tapan Maji et al.   ORGANIC LETTERS

Agelamadins A and B, Dimeric Bromopyrrole Alkaloids from a Marine Sponge Agelas sp.

(2014) Taishi Kusama et al.   ORGANIC LETTERS

A Unified Bioinspired “Aplysinopsin Cascade”: Total Synthesis of (±)-Tubastrindole B and Related Biosynthetic Congeners

(2014) Adam Skiredj et al.   ORGANIC LETTERS

Urupocidin A: A New, Inducing iNOS Expression Bicyclic Guanidine Alkaloid from the Marine Sponge Monanchora pulchra

(2014) Tatyana N. Makarieva et al.   ORGANIC LETTERS

Total Synthesis of Callipeltin B and M, Peptidyl Marine Natural Products

(2014) Mari Kikuchi et al.   ORGANIC LETTERS

Alchornedine, a New Anti-Trypanosomal Guanidine Alkaloid from Alchornea glandulosa

(2014) Kaidu Barrosa et al.   PLANTA MEDICA

Confirmation and Distribution of Tetrodotoxin for the First Time in Terrestrial Invertebrates: Two Terrestrial Flatworm Species (Bipalium adventitium and Bipalium kewense)

(2014) Amber N. Stokes et al.   PLoS One

Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives

(2014) Liang Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure–activity relationships of guanylated antimicrobial polymethacrylates

(2014) Katherine E.S. Locock et al.   PURE AND APPLIED CHEMISTRY

Direct Guanylation of Amino Groups by Cyanamide in Water: Catalytic Generation and Activation of Unsubstituted Carbodiimide by Scandium(III) Triflate

(2014) Katsunori Tanaka et al.   SYNLETT

Convenient Synthesis of Acyclic Guanidines from Isothiouronium Iodides and Amines without Protection of the Amino Groups

(2014) Takeshi Endo et al.   SYNLETT

A Short Synthesis of Partially Protected l- and d-β-Hydroxyenduracididines and a Structurally Simplified Dipeptide Analogue

(2014) Markus Oberthür et al.   SYNTHESIS-STUTTGART

Iodocyclisations reactions of Boc- and Cbz-protected N-allylguanidines

(2014) Zainab Al Shuhaib et al.   TETRAHEDRON

Direct Ras inhibitors identified from a structurally rigidified bicyclic peptide library

(2014) Punit Upadhyaya et al.   TETRAHEDRON

Three aeruginosins and a microviridin from a bloom assembly of Microcystis spp. collected from a fishpond near Kibbutz Lehavot HaBashan, Israel

(2014) Margarita Vegman et al.   TETRAHEDRON

Facile solid phase synthesis of N-cycloguanidinyl-formyl peptides

(2014) Xiaoxiao Yang et al.   TETRAHEDRON LETTERS

Microwave-assisted guanidinylation in solid phase peptide synthesis: comparison of various reagents

(2014) Ewa Witkowska et al.   TETRAHEDRON LETTERS

Enantioselective Michael addition of isobutyraldehyde to nitroalkenes organocatalyzed by chiral primary amine-guanidines

(2014) Angel Avila et al.   TETRAHEDRON-ASYMMETRY

Sulfonamides with Potent Inhibitory Action and Selectivity against the α-Carbonic Anhydrase from Vibrio cholerae

(2014) Mariangela Ceruso et al.   ACS Medicinal Chemistry Letters

Expansion of Antibacterial Spectrum of Muraymycins toward Pseudomonas aeruginosa

(2014) Yusuke Takeoka et al.   ACS Medicinal Chemistry Letters

Synthesis of N-urethane protected amino alkyl (S-methyl)-isothiouronium compounds and carbodiimide tethered peptidomimetics: an application for guanidino and substituted guanidino peptidomimetics synthesis

(2014) Basavaprabhu Hosamani et al.   RSC Advances

Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection

(2014) Vaishali Bane et al.   Toxins

Asymmetric Michael Reaction of Nitroolefins with β-Dicarbonyl Compounds Catalysed by 1,3-Diamine-Tethered Guanidine-Thiourea Bifunctional Organocatalysts

(2014) Natsuko Horitsugi et al.   Asian Journal of Organic Chemistry

Fifteen Years of Cell-Penetrating, Guanidinium-Rich Molecular Transporters: Basic Science, Research Tools, and Clinical Applications

(2013) Erika Geihe Stanzl et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Common Origin for Guanidinobutanoate Starter Units in Antifungal Natural Products

(2013) Hui Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Very Strong Organosuperbases Formed by Combining Imidazole and Guanidine Bases: Synthesis, Structure, and Basicity

(2013) Katarina Vazdar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Neuraminidase inhibitors for influenza B virus infection: Efficacy and resistance

(2013) Andrew J. Burnham et al.   ANTIVIRAL RESEARCH

Evolutionary Acquisition and Loss of Saxitoxin Biosynthesis in Dinoflagellates: the Second “Core” Gene,sxtG

(2013) Russell J. S. Orr et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Guanylated Polymethacrylates: A Class of Potent Antimicrobial Polymers with Low Hemolytic Activity

(2013) Katherine E. S. Locock et al.   BIOMACROMOLECULES

Synthesis and structure–activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists

(2013) Ayako Moritomo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

N-terminal guanidinylation of TIPP (Tyr-Tic-Phe-Phe) peptides results in major changes of the opioid activity profile

(2013) Grazyna Weltrowska et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecules of Keystone Significance

(2013) Ryan P. Ferrer et al.   BIOSCIENCE

Mechanism of cytotoxic action of crambescidin-816 on human liver-derived tumour cells

(2013) J A Rubiolo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Synthesis of highly substituted oxetanes via [2+2] cycloaddition reactions of allenoates catalyzed by a guanidine Lewis base

(2013) Philipp Selig et al.   CHEMICAL COMMUNICATIONS

Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation: direct access to pyrroloindolines and furoindolines

(2013) Wenchao Chen et al.   CHEMICAL COMMUNICATIONS

Guanidine bridged nucleic acid (GuNA): an effect of a cationic bridged nucleic acid on DNA binding affinity

(2013) Ajaya R. Shrestha et al.   CHEMICAL COMMUNICATIONS

Synthesis of Tetrodotoxin, a Classic but Still Fascinating Natural Product

(2013) Toshio Nishikawa et al.   CHEMICAL RECORD

Nitro-Mannich Reaction

(2013) Adam Noble et al.   CHEMICAL REVIEWS

Bisguanidines with Biphenyl, Binaphthyl, and Bipyridyl Cores: Proton-Sponge Properties and Coordination Chemistry

(2013) Astrid Maronna et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric α-Hydroxylation of Tetralone-Derived β-Ketoesters by Using a Guanidine-Urea Bifunctional Organocatalyst in the Presence of Cumene Hydroperoxide

(2013) Minami Odagi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric α-Hydroxylation of a Lactone with Vinylogous Pyridone by Using a Guanidine-Urea Bifunctional Organocatalyst: Catalytic Enantioselective Synthesis of a Key Intermediate for (20S)-Camptothecin Analogues

(2013) Tatsuya Watanabe et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bicyclic-Guanidine-Catalyzed Asymmetric Michael Addition of 3-Substituted Oxindoles to 2-Cyclopentenone

(2013) Caiyun Yang et al.   Chemistry-An Asian Journal

Synthesis of Guanidines from Amines and Carbodiimides Catalyzed by Mono-Indenyl-Ligated Rare Earth Metal Bis(silylamide) Complexes

(2013) Jue Chen et al.   CHINESE JOURNAL OF CHEMISTRY

Thiourea and Guanidine Derivatives as Antimalarial and Antimicrobial Agents§

(2013) Amita Mishra et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Asymmetric niobium guanidinates as intermediates in the catalytic guanylation of amines

(2013) David Elorriaga et al.   DALTON TRANSACTIONS

Early physiological and biochemical responses of rice seedlings to low concentration of microcystin-LR

(2013) Catarina C. Azevedo et al.   ECOTOXICOLOGY

Synthesis and biological evaluation of guanidino analogues of roscovitine

(2013) Iva Dolečková et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N′-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII

(2013) Beata Żołnowska et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective Synthesis of Succinimides by Michael Addition of Aldehydes to Maleimides Organocatalyzed by Chiral Primary Amine-Guanidines

(2013) Angel Avila et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Biological activities of guanidine compounds, 2008 – 2012 update

(2013) Franciszek Sączewski et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Microcystins and two new micropeptin cyanopeptides produced by unprecedented Microcystis aeruginosa blooms in North Carolina's Cape Fear River

(2013) Justin D. Isaacs et al.   HARMFUL ALGAE

Puffer smells tetrodotoxin

(2013) Kogen Okita et al.   ICHTHYOLOGICAL RESEARCH

Spatial and Temporal Instability of Local Biotic Community Mediate a Form of Aposematic Defense in Newts, Consisting of Carotenoid-Based Coloration and Tetrodotoxin

(2013) Koji Mochida et al.   JOURNAL OF CHEMICAL ECOLOGY

Aminoalkyl Derivatives of Guanidine Diaromatic Minor Groove Binders with Antiprotozoal Activity

(2013) Caitriona McKeever et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cyclic Enkephalins with a Diversely Substituted Guanidine Bridge or a Thiourea Bridge: Synthesis, Biological and Structural Evaluations

(2013) Youness Touati-Jallabe et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure–Activity Relationship Studies of Argiotoxins: Selective and Potent Inhibitors of Ionotropic Glutamate Receptors

(2013) Mette H. Poulsen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Guanidine Alkaloids from Plumbago zeylanica

(2013) Hai-Jian Cong et al.   JOURNAL OF NATURAL PRODUCTS

Structural Characterization of the Heterobactin Siderophores from Rhodococcus erythropolis PR4 and Elucidation of Their Biosynthetic Machinery

(2013) Mattia Bosello et al.   JOURNAL OF NATURAL PRODUCTS

An Improved Synthesis of (−)-5,11-Dideoxytetrodotoxin

(2013) Masaatsu Adachi et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Stereoselective Synthesis of Trisubstituted Cyclohexanols Using a Guanidine-Catalyzed Tandem Henry–Michael Reaction

(2013) Qipu Dai et al.   JOURNAL OF ORGANIC CHEMISTRY

Design of Superbasic Guanidines: The Role of Multiple Intramolecular Hydrogen Bonds

(2013) Danijela Barić et al.   JOURNAL OF ORGANIC CHEMISTRY

Maleimide Conjugates of Saxitoxin as Covalent Inhibitors of Voltage-Gated Sodium Channels

(2013) William H. Parsons et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Activity of Biomimetic Biofilm Disruptors

(2013) Thomas Böttcher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interdigitated Hydrogen Bonds: Electrophile Activation for Covalent Capture and Fluorescence Turn-On Detection of Cyanide

(2013) Junyong Jo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crambescidin-816 Acts as a Fungicidal with More Potency than Crambescidin-800 and -830, Inducing Cell Cycle Arrest, Increased Cell Size and Apoptosis in Saccharomyces cerevisiae

(2013) Juan Rubiolo et al.   Marine Drugs

New Azalomycin F Analogs from Mangrove Streptomyces sp. 211726 with Activity against Microbes and Cancer Cells

(2013) Ganjun Yuan et al.   Marine Drugs

Evolution and Distribution of Saxitoxin Biosynthesis in Dinoflagellates

(2013) Russell Orr et al.   Marine Drugs

An Overview on the Marine Neurotoxin, Saxitoxin: Genetics, Molecular Targets, Methods of Detection and Ecological Functions

(2013) Kathleen Cusick et al.   Marine Drugs

2-Aminoimidazoles in Medicinal Chemistry

(2013) AleŠ Žula et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Lichen species identity and diversity of cyanobacterial toxins in symbiosis

(2013) Ulla Kaasalainen et al.   NEW PHYTOLOGIST

Synthesis and biological studies of neopetrosiamides as inhibitors of cancer cell invasion

(2013) Kaitlyn M. Towle et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of acylguanidine zanamivir derivatives as neuraminidase inhibitors and the evaluation of their bio-activities

(2013) Chien-Hung Lin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties

(2013) Balakrishna Dulla et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of saxitoxin derivatives bearing guanidine and urea groups at C13 and evaluation of their inhibitory activity on voltage-gated sodium channels

(2013) Takafumi Akimoto et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Sequential enantiodivergent organocatalysis: reversibility in enantioswitching controlled by a conformationally flexible guanidine/bisthiourea organocatalyst

(2013) Yoshihiro Sohtome et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of crambescin B carboxylic acid, a potent inhibitor of voltage-gated sodium channels

(2013) Atsuo Nakazaki et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of c-di-GMP Analogs with Thiourea, Urea, Carbodiimide, and Guanidinium Linkages

(2013) Barbara L. Gaffney et al.   ORGANIC LETTERS

Synthesis of Plantazolicin Analogues Enables Dissection of Ligand Binding Interactions of a Highly Selective Methyltransferase

(2013) Abhishek Sharma et al.   ORGANIC LETTERS

Synthesis of Cyclic Guanidines via Pd-Catalyzed Alkene Carboamination

(2013) Blane P. Zavesky et al.   ORGANIC LETTERS

Development of Tartaric Acid Derived Chiral Guanidines and Their Application to Catalytic Enantioselective α-Hydroxylation of β-Dicarbonyl Compounds

(2013) Liwei Zou et al.   ORGANIC LETTERS

Nagelamides X–Z, Dimeric Bromopyrrole Alkaloids from a Marine Sponge Agelas sp.

(2013) Naonobu Tanaka et al.   ORGANIC LETTERS

Synthesis of guanidinium-based anion exchange membranes and their stability assessment

(2013) Syed D Sajjad et al.   POLYMERS FOR ADVANCED TECHNOLOGIES

Mechanism-Based Covalent Neuraminidase Inhibitors with Broad-Spectrum Influenza Antiviral Activity

(2013) J.-H. Kim et al.   SCIENCE

Anion transport across phospholipid bilayers promoted by a guanidinium calix[4]arene conjugate

(2013) Sabina Licen et al.   SUPRAMOLECULAR CHEMISTRY

Organic Superbases: The Concept at a Glance

(2013) Tsutomu Ishikawa et al.   SYNLETT

Synthesis of Aroylguanidines by an Unexpected Demethylation-Addition Cascade

(2013) Zhen Guo et al.   SYNTHESIS-STUTTGART

Guanidine Organocatalysis

(2013) Philipp Selig   SYNTHESIS-STUTTGART

Eight micropeptins from a Microcystis spp. bloom collected from a fishpond near Kibbutz Lehavot HaBashan, Israel

(2013) Margarita Vegman et al.   TETRAHEDRON

Synthesis and biological activity of analogues of batzelladine F

(2013) Elliot L. Bennett et al.   TETRAHEDRON

Sequential- and tandem-oxidation–epoxidation reactions employing guanidine bases

(2013) David J. Phillips et al.   TETRAHEDRON

Concise total synthesis of phidianidine A and B

(2013) Jacob C. Buchanan et al.   TETRAHEDRON LETTERS

Pulchranin A, isolated from the Far-Eastern marine sponge, Monanchora pulchra: the first marine non-peptide inhibitor of TRPV-1 channels

(2013) Alla G. Guzii et al.   TETRAHEDRON LETTERS

Asymmetric synthesis of aminopyrimidine and cyclic guanidine amino acids

(2013) Vicki D. Möschwitzer et al.   TETRAHEDRON LETTERS

Nagelamides U–W, bromopyrrole alkaloids from a marine sponge Agelas sp.

(2013) Naonobu Tanaka et al.   TETRAHEDRON LETTERS

Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach

(2013) Roland Geyer et al.   MedChemComm

A single betaproteobacterium dominates the microbial community of the crambescidine-containing sponge Crambe crambe

(2013) Julie Croué et al.   Scientific Reports

Antitumor Effects of EGFR Antisense Guanidine-Based Peptide Nucleic Acids in Cancer Models

(2012) Sufi M. Thomas et al.   ACS Chemical Biology

Total Synthesis and Biological Evaluation of Phidianidines A and B Uncovers Unique Pharmacological Profiles at CNS Targets

(2012) John T. Brogan et al.   ACS Chemical Neuroscience

Asymmetric Total Synthesis of (+)-Merobatzelladine B

(2012) Nicholas R. Babij et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and evaluation of new guanidine-thiourea organocatalyst for the nitro-Michael reaction: Theoretical studies on mechanism and enantioselectivity

(2012) Tatyana E Shubina et al.   Beilstein Journal of Organic Chemistry

Discovery of benzothiazole guanidines as novel inhibitors of thrombin and trypsin IV

(2012) Michael Karle et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Solid-phase synthesis of fusaricidin/li-f class of cyclic lipopeptides: Guanidinylation of resin-bound peptidyl amines

(2012) Nina Bionda et al.   BIOPOLYMERS

Guanidine/Azole Binary System as an Efficient Catalyst for Morita-Baylis-Hillman Reaction

(2012) Masahiro Terada et al.   ChemCatChem

Guanidines: Highly Nucleophilic Organocatalysts

(2012) Biplab Maji et al.   ChemCatChem

Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides

(2012) Lixin Li et al.   CHEMICAL COMMUNICATIONS

Chiral guanidine-catalyzed asymmetric direct vinylogous Michael reaction of α,β-unsaturated γ-butyrolactams with alkylidene malonates

(2012) Yang Yang et al.   CHEMICAL COMMUNICATIONS

Guanidine catalyzed aerobic reduction: a selective aerobic hydrogenation of olefins using aqueous hydrazine

(2012) Manjunath Lamani et al.   CHEMICAL COMMUNICATIONS

Transition metal-catalyzed N-arylations of amidines and guanidines

(2012) Tom R. M. Rauws et al.   CHEMICAL SOCIETY REVIEWS

Amidines, isothioureas, and guanidines as nucleophilic catalysts

(2012) James E. Taylor et al.   CHEMICAL SOCIETY REVIEWS

Putative Binding Sites, and Pathways to Them, for Amidine and Guanidine Current Inhibitors on Acid-Sensing Ion Channels (ASIC). A Theoretical Approach with hASIC1a Homology Model

(2012) Francesco Pietra   CHEMISTRY & BIODIVERSITY

Chiral Guanidine-catalyzed 1,4-Addition Reaction of 5H-Oxazol-4-ones to Alkynones

(2012) Tomonori Misaki et al.   CHEMISTRY LETTERS

Heterocyclic superbases: retrospective and current trends

(2012) A. F. Pozharskii et al.   Chemistry of Heterocyclic Compounds

Orthogonal CN Plus CC Tandem Reaction of Iodoanilines Leading to Styrylguanidines Catalyzed by Supported Palladium Nanoparticles

(2012) Abdessamad Grirrane et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Synthesis of 2,3-Dihydroquinolin-4-one Derivatives Catalyzed by a Chiral Bisguanidium Salt

(2012) Xiao Xiao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Selectively Guanidinylated Aminoglycosides as Antibiotics

(2012) Richard J. Fair et al.   ChemMedChem

Recent Advances in Neuraminidase Inhibitor Development as Anti-influenza Drugs

(2012) Enguang Feng et al.   ChemMedChem

Aluminum chloride: A highly efficient catalyst for addition of amines to carbodiimides to synthesize substituted guanidines

(2012) XueHua Zhu et al.   CHINESE SCIENCE BULLETIN

Phylogeny of Microcystins: Evidence of a Biogeographical Trend?

(2012) Cristiana Moreira et al.   CURRENT MICROBIOLOGY

Environmental conditions that influence toxin biosynthesis in cyanobacteria

(2012) Brett A. Neilan et al.   ENVIRONMENTAL MICROBIOLOGY

Strong Organic Bases as Building Blocks of Mesoporous Hybrid Catalysts for C-C Forming Bond Reactions

(2012) Enrica Gianotti et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Antifungal Diterpene Alkaloids from the Caribbean Sponge Agelas citrina: Unified Configurational Assignments of Agelasidines and Agelasines

(2012) E. Paige Stout et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Microwave-Assisted Synthesis of Guanidine Organocatalysts Bearing a Tetrahydroisoquinoline Framework and Their Evaluation in Michael Addition Reactions

(2012) Tricia Naicker et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Design and Development of Bioinspired Guanine-Based Organic Catalyst for Asymmetric Catalysis

(2012) Gal Suez et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

High in vitro antimicrobial activity of β-peptoid–peptide hybrid oligomers against planktonic and biofilm cultures of Staphylococcus epidermidis

(2012) Yang Liu et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Nodularin, a cyanobacterial toxin, is synthesized in planta by symbiotic Nostoc sp.

(2012) Michelle M Gehringer et al.   ISME Journal

Predatory Caddisfly Larvae Sequester Tetrodotoxin from Their Prey, Eggs of the Rough-Skinned Newt (Taricha granulosa)

(2012) Brian G. Gall et al.   JOURNAL OF CHEMICAL ECOLOGY

Depuration of Tetrodotoxin and Changes in Bacterial Communities in Pleurobranchea maculata Adults and Egg Masses Maintained in Captivity

(2012) Susanna A. Wood et al.   JOURNAL OF CHEMICAL ECOLOGY

Akwaton, polyhexamethylene-guanidine hydrochloride-based sporicidal disinfectant: a novel tool to fight bacterial spores and nosocomial infections

(2012) M. K. Oule et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Selective Mode of Action of Guanidine-Containing Non-Peptides at Human NPFF Receptors

(2012) Maria Findeisen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Acyl Guanidine Inhibitors of β-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis

(2012) Samuel W. Gerritz et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Bactericidal Guanidinomethyl Biaryl That Alters the Dynamics of Bacterial FtsZ Polymerization

(2012) Malvika Kaul et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cytotoxic Cyclic Depsipeptides from the Australian Marine Sponge Neamphius huxleyi

(2012) Trong D. Tran et al.   JOURNAL OF NATURAL PRODUCTS

Metabolites of Microcystis aeruginosa Bloom Material from Lake Kinneret, Israel

(2012) Marina Lifshits et al.   JOURNAL OF NATURAL PRODUCTS

Palau’amine and Related Oroidin Alkaloids Dibromophakellin and Dibromophakellstatin Inhibit the Human 20S Proteasome

(2012) Theresa A. Lansdell et al.   JOURNAL OF NATURAL PRODUCTS

Synthesis of Phidianidines A and B

(2012) Hong-Yu Lin et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Symmetrical and Unsymmetrical N,N′-Diaryl Guanidines via Copper/N-Methylglycine-Catalyzed Arylation of Guanidine Nitrate

(2012) Hui Xing et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Ureidomuraymycidine Derivatives for Structure– Activity Relationship Studies of Muraymycins

(2012) Bilal A. Aleiwi et al.   JOURNAL OF ORGANIC CHEMISTRY

Origin of Asymmetric Induction in Bicyclic Guanidine-Catalyzed Thio-Michael Reaction: A Bifunctional Mode of Lewis Acid-Brønsted Acid Activation

(2012) Bokun Cho et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of short cationic antimicrobial peptidomimetics containing arginine analogues

(2012) Leonardo Baldassarre et al.   JOURNAL OF PEPTIDE SCIENCE

Molecular Basis for Nanoscopic Membrane Curvature Generation from Quantum Mechanical Models and Synthetic Transporter Sequences

(2012) Nathan W. Schmidt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of Amination of β-Keto Esters by Azadicarboxylates Catalyzed by an Axially Chiral Guanidine: Acyclic Keto Esters React through an E Enolate

(2012) Luis Simón et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor

(2012) Tracy C. Holmes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cyclic Guanidines as Efficient Organocatalysts for the Synthesis of Polyurethanes

(2012) Jérome Alsarraf et al.   MACROMOLECULES

Isolation and Structural Determination of the First 8-epi-type Tetrodotoxin Analogs from the Newt, Cynops ensicauda popei, and Comparison of Tetrodotoxin Analogs Profiles of This Newt and the Puffer Fish, Fugu poecilonotus

(2012) Yuta Kudo et al.   Marine Drugs

Tetrodotoxin (TTX) as a Therapeutic Agent for Pain

(2012) Francisco Rafael Nieto et al.   Marine Drugs

Evolution of Saxitoxin Synthesis in Cyanobacteria and Dinoflagellates

(2012) Jeremiah D. Hackett et al.   MOLECULAR BIOLOGY AND EVOLUTION

The chemistry and biology of organic guanidine derivatives

(2012) Roberto G. S. Berlinck et al.   NATURAL PRODUCT REPORTS

A stand-alone adenylation domain forms amide bonds in streptothricin biosynthesis

(2012) Chitose Maruyama et al.   Nature Chemical Biology

Non-peptidic cell-penetrating agents: synthesis of oligomeric chiral bicyclic guanidinium vectors

(2012) Julián Valero et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Exploring the effect of aminoglycoside guanidinylation on ligands for Tau exon 10 splicing regulatory element RNA

(2012) Paula López-Senín et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Latent catalysts based on guanidine templates for polyurethane synthesis

(2012) Jérome Alsarraf et al.   Polymer Chemistry

Adaptive evolution of voltage-gated sodium channels: The first 800 million years

(2012) H. H. Zakon   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes

(2012) C. R. Feldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis of saxitoxins

(2012) Osamu Iwamoto et al.   PURE AND APPLIED CHEMISTRY

Total Synthesis of (±)-Dragmacidin E; Problems Solved and Lessons Learned

(2012) Ken Feldman et al.   SYNLETT

Catalytic guanylation of aliphatic, aromatic, heterocyclic primary and secondary amines using nanocrystalline zinc(II) oxide

(2012) M. Lakshmi Kantam et al.   TETRAHEDRON

Antioxidant benzylidene 2-aminoimidazolones from the Mediterranean sponge Phorbas topsenti

(2012) Tien Dat Nguyen et al.   TETRAHEDRON

New bioactive alkaloids from the marine sponge Stylissa sp.

(2012) Mostafa A. Fouad et al.   TETRAHEDRON

Generation of diverse 1-(isoquinolin-1-yl)guanidines via a sequential multi-component/cross-coupling reaction

(2012) Chao Ye et al.   TETRAHEDRON

A facile IL–DMSO assisted synthesis of 5-, 6-, and 7-membered benzo-annelated cyclic guanidines

(2012) Amit Verma et al.   TETRAHEDRON LETTERS

o-Iodoxybenzoic acid mediated oxidative condensation: synthesis of guanidines using 1,-3-disubstituted thiourea precursors

(2012) Prasad S. Dangate et al.   TETRAHEDRON LETTERS

Corrigendum to: “Donnazoles A and B from Axinella donnani sponge: very close derivatives from the postulated intermediate ‘pre-axinellamine’” [Tetrahedron Lett. 53(44) (2012) 5828–5832]

(2012) Julie Muñoz et al.   TETRAHEDRON LETTERS

First iron-catalyzed guanylation of amines: a simple and highly efficient protocol to guanidines

(2012) Srinivas Pottabathula et al.   TETRAHEDRON LETTERS

Donnazoles A and B from Axinella donnani sponge: very close derivatives from the postulated intermediate ‘pre-axinellamine’

(2012) Julie Muñoz et al.   TETRAHEDRON LETTERS

Monanchomycalins A and B, unusual guanidine alkaloids from the sponge Monanchora pulchra

(2012) Tatyana N. Makarieva et al.   TETRAHEDRON LETTERS

Microwave-assisted synthesis of highly functionalized guanidines on soluble polymer support

(2012) Chih-Hau Chen et al.   TETRAHEDRON LETTERS

Enantioselective Michael addition of α,α-disubstituted aldehydes to maleimides organocatalyzed by chiral primary amine-guanidines

(2012) Angel Avila et al.   TETRAHEDRON-ASYMMETRY

Tetrodotoxin does not protect red-spotted newts, Notophthalmus viridescens, from intestinal parasites

(2012) Dietrich Mebs et al.   TOXICON

Female newts (Taricha granulosa) produce tetrodotoxin laden eggs after long term captivity

(2012) Brian G. Gall et al.   TOXICON

The molecular mystique of tetrodotoxin

(2012) Edward G. Moczydlowski   TOXICON

Additional bioactive guanidine alkaloids from the Mediterranean sponge Crambe crambe

(2012) Stéphanie Bondu et al.   RSC Advances

Unprecedented spiro-annelated sugar isoureas, guanidines and amidines as new families of glycosidase inhibitors

(2012) Penélope Merino-Montiel et al.   RSC Advances

Synthesis of Guanidinium Functionalized Polycarbodiimides and Their Antibacterial Activities

(2012) Januka Budhathoki-Uprety et al.   ACS Macro Letters

Recognition of Double-Stranded RNA by Guanidine-Modified Peptide Nucleic Acids

(2011) Pankaj Gupta et al.   BIOCHEMISTRY

Arginine Mimetics Using α-Guanidino Acids: Introduction of Functional Groups and Stereochemistry Adjacent to Recognition Guanidiniums in Peptides

(2011) Shalini Balakrishnan et al.   CHEMBIOCHEM

Synthesis and Pharmacological Evaluation of Novel Arginine Analogs as Potential Inhibitors of Acetylcholine-Induced Relaxation in Rat Thoracic Aortic Rings

(2011) Manish Jain et al.   Chemical Biology & Drug Design

Garter snakes do not respond to TTX via chemoreception

(2011) Leleña A. Avila et al.   CHEMOECOLOGY

Chemical investigations of defensive steroid sequestration by the Asian snake Rhabdophis tigrinus

(2011) Deborah A. Hutchinson et al.   CHEMOECOLOGY

Accumulation and phytotoxicity of microcystin-LR in rice (Oryza sativa)

(2011) Jian Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Analysis of microcystins and microcystin genes in 60–170-year-old dried herbarium specimens of cyanobacteria

(2011) J.S. Metcalf et al.   HARMFUL ALGAE

Simple methods for the preparation of N-triflyl guanidines and the structure of compounds with the CF3SO2NCN fragment

(2011) Bagrat A. Shainyan et al.   JOURNAL OF FLUORINE CHEMISTRY

Direct Guanidinylation of Aryl and Heteroaryl Halides via Copper-Catalyzed Cross-Coupling Reaction

(2011) Hassan Hammoud et al.   JOURNAL OF ORGANIC CHEMISTRY

Determining the Absolute Configuration of Two Marine Compounds Using Vibrational Chiroptical Spectroscopy

(2011) Kathrin H. Hopmann et al.   JOURNAL OF ORGANIC CHEMISTRY

An efficient approach to dispacamide A and its derivatives

(2011) Solène Guihéneuf et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Anion mediated activation of guanidine rich small molecules

(2011) Abhigyan Som et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Plantazolicin A and B: Structure Elucidation of Ribosomally Synthesized Thiazole/Oxazole Peptides fromBacillus amyloliquefaciensFZB42

(2011) Bahar Kalyon et al.   ORGANIC LETTERS

Discovery of Nuclear-Encoded Genes for the Neurotoxin Saxitoxin in Dinoflagellates

(2011) Anke Stüken et al.   PLoS One

Variability of tetrodotoxin and of its analogues in the red-spotted newt, Notophthalmus viridescens (Amphibia: Urodela: Salamandridae)

(2011) Mari Yotsu-Yamashita et al.   TOXICON

Plantazolicin, a Novel Microcin B17/Streptolysin S-Like Natural Product from Bacillus amyloliquefaciens FZB42

(2010) R. Scholz et al.   JOURNAL OF BACTERIOLOGY