NMR Fingerprints of the Drug-like Natural-Product Space Identify Iotrochotazine A: A Chemical Probe to Study Parkinson’s Disease

Conithiaquinones A and B, Tetracyclic Cytotoxic Meroterpenes from the Mediterranean AscidianAplidium conicum

(2013) Marialuisa Menna et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Thiaplakortones A–D: Antimalarial Thiazine Alkaloids from the Australian Marine Sponge Plakortis lita

(2013) Rohan A. Davis et al.   JOURNAL OF ORGANIC CHEMISTRY

The Vps35 D620N Mutation Linked to Parkinson's Disease Disrupts the Cargo Sorting Function of Retromer

(2013) Jordan Follett et al.   TRAFFIC

Total Synthesis of Thiaplakortone A: Derivatives as Metabolically Stable Leads for the Treatment of Malaria

(2013) Rebecca H. Pouwer et al.   ACS Medicinal Chemistry Letters

Drug-like Properties: Guiding Principles for the Design of Natural Product Libraries

(2011) David Camp et al.   JOURNAL OF NATURAL PRODUCTS

Similar interactions of natural products with biosynthetic enzymes and therapeutic targets could explain why nature produces such a large proportion of existing drugs

(2011) Esther Kellenberger et al.   NATURAL PRODUCT REPORTS

NRF2 Activation Restores Disease Related Metabolic Deficiencies in Olfactory Neurosphere-Derived Cells from Patients with Sporadic Parkinson's Disease

(2011) Anthony L. Cook et al.   PLoS One

Disease-specific, neurosphere-derived cells as models for brain disorders

(2010) N. Matigian et al.   Disease Models & Mechanisms

Evolving Trends in the Dereplication of Natural Product Extracts: New Methodology for Rapid, Small-Scale Investigation of Natural Product Extracts

(2008) Gerhard Lang et al.   JOURNAL OF NATURAL PRODUCTS

Developing a Drug-like Natural Product Library⊥

(2008) Ronald J. Quinn et al.   JOURNAL OF NATURAL PRODUCTS