Transition metal-catalyzed N-arylations of amidines and guanidines

On the Importance of an Acid Additive in the Synthesis of Pyrido[1,2-a]benzimidazoles by Direct Copper-Catalyzed Amination

(2011) Kye-Simeon Masters et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Protocol to 2-Aminobenzimidazoles via Copper-Catalyzed Cascade Addition and Cyclization ofo-Haloanilines and Carbodiimides

(2011) Fei Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Mediated Synthesis of Substituted 2-Aryl-N-benzylbenzimidazoles and 2-Arylbenzoxazoles via C–H Functionalization/C–N/C–O Bond Formation

(2011) Murali Mohan Guru et al.   JOURNAL OF ORGANIC CHEMISTRY

Ligand-Free Copper-Catalyzed Arylation of Amidines

(2011) Michelle Cortes-Salva et al.   JOURNAL OF ORGANIC CHEMISTRY

Chemical and Pharmacological Significance of Natural Guanidines from Marine Invertebrates

(2011) S. S. Ebada et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Copper(II) Acetate/Oxygen-Mediated Nucleophilic Addition and Intramolecular CH Activation/CN or CC Bond Formation: One-Pot Synthesis of Benzimidazoles or Quinazolines

(2010) Hua-Feng He et al.   ADVANCED SYNTHESIS & CATALYSIS

Regioselective Functionalization of the Imidazole Ring via Transition Metal-Catalyzed CN and CC Bond Forming Reactions

(2010) Fabio Bellina et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper-Catalyzed One-Pot Synthesis of Substituted Benzimidazoles

(2010) Hongwei Jin et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Benzoxazole and Benzimidazole Derivatives via Ligand-Free Copper(I)-Catalyzed Cross-Coupling Reaction of o-Halophenols or o-Haloanilines with Carbodiimides

(2010) Guodong Shen et al.   ADVANCED SYNTHESIS & CATALYSIS

Design and synthesis of new anticancer pyrimidines with multiple-kinase inhibitory effect

(2010) Ibrahim Mustafa El-Deeb et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives

(2010) Cheryl S. Leung et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

N-Aryltriazole ribonucleosides with potent antiproliferative activity against drug-resistant pancreatic cancer

(2010) Yang Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase

(2010) Cristina Maccallini et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A flow-based synthesis of Imatinib: the API of Gleevec

(2010) Mark D. Hopkin et al.   CHEMICAL COMMUNICATIONS

Properties of a novel acid dye 1-amino-4-[(6-nitro-2-benzothiazolyl)amino]-9,10-anthraquinone-2-sulfonic acid with anti-UV capability

(2010) Hao Fei Huang et al.   CHINESE CHEMICAL LETTERS

The mechanism of the modified Ullmann reaction

(2010) Elena Sperotto et al.   DALTON TRANSACTIONS

Lanthanide Complexes Coordinated by a Dianionic Bis(amidinate) Ligand with a Rigid Naphthalene Linker

(2010) Marina V. Yakovenko et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Copper-Catalyzed Intramolecular C−N Bond Formation: A Straightforward Synthesis of Benzimidazole Derivatives in Water

(2010) Jinsong Peng et al.   JOURNAL OF ORGANIC CHEMISTRY

A Direct Intramolecular C−H Amination Reaction Cocatalyzed by Copper(II) and Iron(III) as Part of an Efficient Route for the Synthesis of Pyrido[1,2-a]benzimidazoles fromN-Aryl-2-aminopyridines

(2010) Honggen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ziconotide for treatment of severe chronic pain

(2010) Achim Schmidtko et al.   LANCET

Cobalt-catalyzed intramolecular C–N and C–O cross-coupling reactions: synthesis of benzimidazoles and benzoxazoles

(2010) Prasenjit Saha et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Copper-Catalyzed Guanidinylation of Aryl Iodides: The Formation ofN,N′-Disubstituted Guanidines

(2010) Michelle Cortes-Salva et al.   ORGANIC LETTERS

Rhodium(NHC)-Catalyzed Amination of Aryl Bromides

(2010) Min Kim et al.   ORGANIC LETTERS

Reactions of an Aluminum Amide with Aromatic Nitriles: Formation of Al−N−C Frameworks

(2010) K. Maheswari et al.   ORGANOMETALLICS

A novel and practical synthesis of substituted 2-ethoxy benzimidazole: candesartan cilexetil

(2010) Ping Wang et al.   TETRAHEDRON

Synthesis of new tetracyclic azaheteroaromatic cores via auto-tandem Pd-catalyzed and one-pot Pd- and Cu-catalyzed double C–N bond formation

(2010) Tom R.M. Rauws et al.   TETRAHEDRON

Synthesis and properties of bis(pyrazino[2′,3′:4,5]imidazole)-fused 1,2,5,6-tetrahydro-1,4,5,8,9,10-hexaazaanthracenes: a new fluorescent nitrogen-rich heterocycle

(2010) Sojiro Hachiya et al.   TETRAHEDRON LETTERS

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

(2010) Timothy Noël et al.   Chemical Science

Dialkylbiaryl phosphines in Pd-catalyzed amination: a user's guide

(2010) David S. Surry et al.   Chemical Science

Copper-Catalyzed Synthesis of 1,2,4-Benzothiadiazine 1,1-Dioxide Derivatives by Coupling of 2-Halobenzenesulfonamides with Amidines

(2009) Daoshan Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

On the Role of Metal Contaminants in Catalyses with FeCl3

(2009) Stephen L. Buchwald et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic CC, CN, and CO Ullmann-Type Coupling Reactions

(2009) Florian Monnier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Domino Direct Arylation/N-Arylation: Convenient Synthesis of Phenanthridines

(2009) David A. Candito et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery and structure–activity relationships of a novel class of quinazoline glucokinase activators

(2009) Tomoharu Iino et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1-(3-Aryloxyaryl)benzimidazole sulfones are liver X receptor agonists

(2009) Jeremy M. Travins et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Small molecule probes that target Ablkinase

(2009) Karunakaran A. Kalesh et al.   CHEMICAL COMMUNICATIONS

Direct Imidation to Construct 1H-Benzo[d]imidazole through PdII-Catalyzed CH Activation Promoted by Thiourea

(2009) Qing Xiao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Coordination of neutral, methylene bridged bis-guanidyls at palladium

(2009) Majid S. Khalaf et al.   DALTON TRANSACTIONS

Synthesis and cytotoxic activity of 2-methylimidazo[1,2-a]pyridine- and quinoline-substituted 2-aminopyrimidine derivatives

(2009) Miguel Angel Vilchis-Reyes et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 1-Substituted Benzimidazoles fromo-Bromophenyl Isocyanide and Amines

(2009) Alexander V. Lygin et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Reactivity-Controlled Regioselectivity: A Regiospecific Synthesis of 1,2-Disubstituted Benzimidazoles

(2009) Xiaohu Deng et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Microwave-assisted synthesis of quinazolinone derivatives by efficient and rapid iron-catalyzed cyclization in water

(2009) Xiaodong Zhang et al.   GREEN CHEMISTRY

Ligand-free iron/copper cocatalyzed N-arylations of aryl halides with amines under microwave irradiation

(2009) Diliang Guo et al.   GREEN CHEMISTRY

Cu-Mediated SelectiveN-Arylation of Aminotriazole Acyclonucleosides

(2009) Wei Li et al.   HELVETICA CHIMICA ACTA

Syntheses of new quinoline-containing heterocyclic scaffolds using inter- and intramolecular Pd-catalyzed amination

(2009) Borbála Bogányi et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

CuI-Catalyzed Amination of Arylhalides with Guanidines or Amidines: A Facile Synthesis of 1-H-2-Substituted Benzimidazoles

(2009) Xiaohu Deng et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper(I)-Catalyzed Synthesis of Substituted 2-Mercapto Benzimidazoles

(2009) Siva Murru et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Synthesis of 2-Unsubstituted,N-Substituted Benzimidazoles

(2009) Keiichi Hirano et al.   JOURNAL OF ORGANIC CHEMISTRY

Efficient Routes to Pyrazolo[3,4-b]indoles and Pyrazolo[1,5-a]benzimidazoles via Palladium- and Copper-Catalyzed Intramolecular C−C and C−N Bond Formation†

(2009) Sarvesh Kumar et al.   JOURNAL OF ORGANIC CHEMISTRY

Ligand-Free Copper-Catalyzed Synthesis of Substituted Benzimidazoles, 2-Aminobenzimidazoles, 2-Aminobenzothiazoles, and Benzoxazoles

(2009) Prasenjit Saha et al.   JOURNAL OF ORGANIC CHEMISTRY

Facile Synthesis of 1,2,4-Triazoles via a Copper-Catalyzed Tandem Addition−Oxidative Cyclization

(2009) Satoshi Ueda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient and Reusable Copper-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles with Aryl Halides

(2009) A Young Kim et al.   MOLECULES

Rapid synthesis of Abelson tyrosine kinase inhibitors using click chemistry

(2009) Karunakaran A. Kalesh et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A site selective C–H arylation of free-(NH2) adenines with aryl chlorides: Application to the synthesis of 6,8-disubstituted adenines

(2009) Sophian Sahnoun et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A practical strategy for the synthesis of 2-dialkylamino-4-arylamino-6-aminopyrimidines

(2009) Chaomin Li et al.   TETRAHEDRON LETTERS

Mild and efficient ligand-free copper-catalyzed condensation for the synthesis of quinazolines

(2009) Vouy Linh Truong et al.   TETRAHEDRON LETTERS

CH Functionalization/CN Bond Formation: Copper-Catalyzed Synthesis of Benzimidazoles from Amidines

(2008) Gordon Brasche et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biaryl Phosphane Ligands in Palladium-Catalyzed Amination

(2008) David S. Surry et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Simple and Efficient Approach to Quinazolinones under Mild Copper-Catalyzed Conditions

(2008) Xiaowei Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly efficient copper-catalyzed cascade synthesis of quinazoline and quinazolinone derivatives

(2008) Cheng Huang et al.   CHEMICAL COMMUNICATIONS

Discovery and Biological Evaluation of 5-Aryl-2-furfuramides, Potent and Selective Blockers of the Nav1.8 Sodium Channel with Efficacy in Models of Neuropathic and Inflammatory Pain

(2008) Michael E. Kort et al.   JOURNAL OF MEDICINAL CHEMISTRY

Copper-Catalyzed Synthesis of Benzimidazoles via Cascade Reactions ofo-Haloacetanilide Derivatives with Amidine Hydrochlorides

(2008) Daoshan Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Domino Annulation Approaches to the Synthesis of Benzoxazoles under Microwave-Accelerated and Conventional Thermal Conditions

(2008) Russell D. Viirre et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Synthesis of Primary Arylamines via Cascade Reactions of Aryl Halides with Amidine Hydrochlorides

(2008) Xiaoting Gao et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Amination of Aryl and Heteroaryl Tosylates at Room Temperature

(2008) Tokutaro Ogata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Highly Active Catalyst for Pd-Catalyzed Amination Reactions: Cross-Coupling Reactions Using Aryl Mesylates and the Highly Selective Monoarylation of Primary Amines Using Aryl Chlorides

(2008) Brett P. Fors et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Reactive, General and Long-Lived Catalysts for Palladium-Catalyzed Amination of Heteroaryl and Aryl Chlorides, Bromides, and Iodides: Scope and Structure–Activity Relationships

(2008) Qilong Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of New N-Arylpyrimidin-2-amine Derivatives Using a Palladium Catalyst

(2008) Ibrahim El-Deeb et al.   MOLECULES

[(CyPF-tBu)PdCl2]: An Air-Stable, One-Component, Highly Efficient Catalyst for Amination of Heteroaryl and Aryl Halides

(2008) Qilong Shen et al.   ORGANIC LETTERS

A Facile Total Synthesis of Imatinib Base and Its Analogues

(2008) Yi-Feng Liu et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Synthesis of pyrazino[1,2-a]benzimidazol-1(2H)ones via a microwave assisted Buchwald–Hartwig type reaction

(2008) Jo Alen et al.   TETRAHEDRON

First Total Synthesis of Trimeric Indole Alkaloid, Psychotrimine

(2007) Yohei Matsuda et al.   ORGANIC LETTERS